Published in J Immunol Methods on July 01, 2002
Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci U S A (2004) 2.85
Nephritogenic lupus antibodies recognize glomerular basement membrane-associated chromatin fragments released from apoptotic intraglomerular cells. Am J Pathol (2006) 1.32
Structural antitumoral activity relationships of synthetic chalcones. Int J Mol Sci (2009) 1.22
Effects of exercise intensity on lymphocyte apoptosis induced by oxidative stress in men. Eur J Appl Physiol (2005) 1.05
Features of programmed cell death in intact Xenopus oocytes and early embryos revealed by near-infrared fluorescence and real-time monitoring. Cell Death Differ (2010) 0.93
Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus? Arthritis Res Ther (2006) 0.93
FAK and p38-MAP kinase-dependent activation of apoptosis and caspase-3 in retinal endothelial cells by alpha1(IV)NC1. Invest Ophthalmol Vis Sci (2009) 0.91
Activation of the lutropin/choriogonadotropin receptor inhibits apoptosis of immature Leydig cells in primary culture. Endocrinology (2009) 0.88
Cell-to-cell variability in cell death: can systems biology help us make sense of it all? Cell Death Dis (2014) 0.87
Systemic hypoxia promotes lymphocyte apoptosis induced by oxidative stress during moderate exercise. Eur J Appl Physiol (2009) 0.86
Yessotoxin as a tool to study induction of multiple cell death pathways. Toxins (Basel) (2012) 0.83
Molecular mechanisms of apoptosis induced by Scorpio water extract in human hepatoma HepG2 cells. World J Gastroenterol (2005) 0.83
Insulin deprivation decreases caspase-dependent apoptotic signaling in cultured rat sertoli cells. ISRN Urol (2013) 0.80
TNFR1-dependent pulmonary apoptosis during ischemic acute kidney injury. Am J Physiol Lung Cell Mol Physiol (2012) 0.78
Antiproliferative effect of alpinetin in BxPC-3 pancreatic cancer cells. Int J Mol Med (2012) 0.78
Skin sensitizers differentially regulate signaling pathways in MUTZ-3 cells in relation to their individual potency. BMC Pharmacol Toxicol (2014) 0.78
An Investigation of the Cytotoxicity and Caspase-Mediated Apoptotic Effect of Green Synthesized Zinc Oxide Nanoparticles Using Eclipta prostrata on Human Liver Carcinoma Cells. Nanomaterials (Basel) (2015) 0.78
Zebrafish as an Emerging Model Organism to Study Angiogenesis in Development and Regeneration. Front Physiol (2016) 0.77
Apoptosis of epithelial cells and macrophages due to nonpigmented Serratia marcescens strains. ScientificWorldJournal (2012) 0.77
Eliminating caspase-7 and cathepsin B cross-reactivity on fluorogenic caspase-3 substrates. Mol Biosyst (2016) 0.77
Molecular mechanism of apoptosis induction in skin cancer cells by the centipedegrass extract. BMC Complement Altern Med (2013) 0.75
Designing caspase-3 sensors for imaging of apoptosis in living cells. Chemistry (2009) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Regulation of cell death: the calcium-apoptosis link. Nat Rev Mol Cell Biol (2003) 9.07
Mitochondria, oxidative stress and cell death. Apoptosis (2007) 4.29
Mitochondrial oxidative stress: implications for cell death. Annu Rev Pharmacol Toxicol (2007) 3.90
Cytochrome c release from mitochondria proceeds by a two-step process. Proc Natl Acad Sci U S A (2002) 3.57
Mitochondria in cancer cells: what is so special about them? Trends Cell Biol (2008) 2.97
Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci U S A (2004) 2.85
Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis. J Biol Chem (2002) 2.46
DNA damage-induced apoptosis. Oncogene (2004) 2.32
Role of mitochondria in toxic oxidative stress. Mol Interv (2005) 1.76
Cysteine protease mcII-Pa executes programmed cell death during plant embryogenesis. Proc Natl Acad Sci U S A (2005) 1.72
Mitochondrial regulation of cell death: processing of apoptosis-inducing factor (AIF). Biochem Biophys Res Commun (2010) 1.70
Caspase-2 function in response to DNA damage. Biochem Biophys Res Commun (2005) 1.60
Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome. Nat Cell Biol (2009) 1.60
A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis. J Immunol (2002) 1.56
Metacaspase-dependent programmed cell death is essential for plant embryogenesis. Curr Biol (2004) 1.56
Multiple pathways of cytochrome c release from mitochondria in apoptosis. Biochim Biophys Acta (2006) 1.54
Mechanisms of Interferon-alpha induced apoptosis in malignant cells. Oncogene (2002) 1.50
Mathematical modelling of cell-fate decision in response to death receptor engagement. PLoS Comput Biol (2010) 1.49
Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity. Cancer Res (2006) 1.48
Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes. Blood (2005) 1.44
Cell death mechanisms and their implications in toxicology. Toxicol Sci (2010) 1.43
Hsp72 mediates TAp73α anti-apoptotic effects in small cell lung carcinoma cells. J Cell Mol Med (2011) 1.42
Calcium and cell death mechanisms: a perspective from the cell death community. Cell Calcium (2011) 1.39
The Warburg effect and mitochondrial stability in cancer cells. Mol Aspects Med (2009) 1.37
Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells. Exp Hematol (2008) 1.34
The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis. Arch Biochem Biophys (2004) 1.33
Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis. Mol Biol Cell (2005) 1.29
Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway. J Biol Chem (2004) 1.24
Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity. EMBO Rep (2004) 1.21
Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release. Biochem Biophys Res Commun (2005) 1.21
Mitochondria as targets for chemotherapy. Apoptosis (2009) 1.20
Caspase-2 permeabilizes the outer mitochondrial membrane and disrupts the binding of cytochrome c to anionic phospholipids. J Biol Chem (2004) 1.20
Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment. Oncogene (2002) 1.20
Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation. Autophagy (2012) 1.19
The unpredictable caspase-2: what can it do? Trends Cell Biol (2010) 1.19
Mitochondria as targets for cancer chemotherapy. Semin Cancer Biol (2008) 1.14
Free radicals in cross talk between autophagy and apoptosis. Antioxid Redox Signal (2014) 1.13
Role of alterations in the apoptotic machinery in sensitivity of cancer cells to treatment. Curr Pharm Des (2006) 1.12
Cardiolipin is not required for Bax-mediated cytochrome c release from yeast mitochondria. J Biol Chem (2003) 1.11
Apoptosis-inducing factor determines the chemoresistance of non-small-cell lung carcinomas. Oncogene (2004) 1.10
Drug-induced death of the asexual blood stages of Plasmodium falciparum occurs without typical signs of apoptosis. Microbes Infect (2006) 1.09
Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL. Carcinogenesis (2011) 1.07
Cardiolipin oxidation sets cytochrome c free. Nat Chem Biol (2005) 1.07
Concern Chromosomal breaks during mitotic catastrophe trigger γH2AX-ATM-p53-mediated apoptosis. J Cell Sci (2011) 1.03
A quantitative assay for the monitoring of autophagosome accumulation in different phases of the cell cycle. Autophagy (2011) 1.02
Proteases in autophagy. Biochim Biophys Acta (2011) 1.01
Mitochondrial regulation of apoptotic cell death. Chem Biol Interact (2006) 0.99
Autophagy and metacaspase determine the mode of cell death in plants. J Cell Biol (2013) 0.99
Visualization of the compartmentalization of glutathione and protein-glutathione mixed disulfides in cultured cells. FASEB J (2002) 0.98
Endothelial cell surface ATP synthase-triggered caspase-apoptotic pathway is essential for k1-5-induced antiangiogenesis. Cancer Res (2004) 0.97
The mitochondrial TOM complex is required for tBid/Bax-induced cytochrome c release. J Biol Chem (2007) 0.97
Plasma membrane sequestration of apoptotic protease-activating factor-1 in human B-lymphoma cells: a novel mechanism of chemoresistance. Blood (2005) 0.97
The transcriptosomal response of human A549 lung cells to a hydrogen peroxide-generating system: relationship to DNA damage, cell cycle arrest, and caspase activation. Free Radic Biol Med (2004) 0.97
Dexamethasone-induced apoptosis in acute lymphoblastic leukemia involves differential regulation of Bcl-2 family members. Haematologica (2007) 0.97
Peroxiredoxin V is essential for protection against apoptosis in human lung carcinoma cells. Exp Cell Res (2006) 0.97
Carcinogenesis and apoptosis: paradigms and paradoxes. Carcinogenesis (2006) 0.96
Sorafenib has potent antitumor activity against multiple myeloma in vitro, ex vivo, and in vivo in the 5T33MM mouse model. Cancer Res (2012) 0.96
Caspase-2 activation in neural stem cells undergoing oxidative stress-induced apoptosis. Apoptosis (2008) 0.96
Reactive oxygen species generated in different compartments induce cell death, survival, or senescence. Free Radic Biol Med (2013) 0.96
Full-length p73alpha represses drug-induced apoptosis in small cell lung carcinoma cells. J Biol Chem (2005) 0.95
Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processing. Free Radic Biol Med (2010) 0.94
Cell death mechanisms: cross-talk and role in disease. Exp Cell Res (2010) 0.93
Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis. EMBO J (2010) 0.93
Inhibitors of the PI3-kinase/Akt pathway induce mitotic catastrophe in non-small cell lung cancer cells. Int J Cancer (2006) 0.93
Differential regulation of the mitochondrial and death receptor pathways in neural stem cells. Eur J Neurosci (2004) 0.92
Caspases: determination of their activities in apoptotic cells. Methods Enzymol (2008) 0.92
Downregulation of peroxiredoxin V stimulates formation of etoposide-induced double-strand DNA breaks. FEBS Lett (2004) 0.92
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs. Cancer Res (2009) 0.92
Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells. Exp Cell Res (2002) 0.91
Antiapoptotic role of growth factors in the myelodysplastic syndromes: concordance between in vitro and in vivo observations. Clin Cancer Res (2005) 0.90
Autophagy in toxicology: cause or consequence? Annu Rev Pharmacol Toxicol (2012) 0.90
HAMLET, protein folding, and tumor cell death. Biochem Biophys Res Commun (2006) 0.89
Role of mitochondria in toxic cell death. Toxicology (2002) 0.89
Coding polymorphisms in Casp5, Casp8 and DR4 genes may play a role in predisposition to lung cancer. Cancer Lett (2009) 0.89
Expression of caspase-3 and -7 does not correlate with the extent of apoptosis in primary breast carcinomas. Cell Cycle (2002) 0.89
Targeting hepatoma using nitric oxide donor strategies. Antioxid Redox Signal (2012) 0.89
Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF. Br J Haematol (2010) 0.89
Apoptotic pathways and therapy resistance in human malignancies. Adv Cancer Res (2005) 0.89
Phosphoproteomic profiling of NSCLC cells reveals that ephrin B3 regulates pro-survival signaling through Akt1-mediated phosphorylation of the EphA2 receptor. J Proteome Res (2011) 0.89
Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy. Free Radic Biol Med (2011) 0.88