Published in Methods Enzymol on January 01, 2002
Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev (2003) 3.51
The molecular function of Ase1p: evidence for a MAP-dependent midzone-specific spindle matrix. Microtubule-associated proteins. J Cell Biol (2003) 2.39
Molecular control of kinetochore-microtubule dynamics and chromosome oscillations. Nat Cell Biol (2010) 1.61
Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1. J Cell Biol (2010) 1.59
Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore. Nat Cell Biol (2012) 1.25
Bod1, a novel kinetochore protein required for chromosome biorientation. J Cell Biol (2007) 1.22
Microtubule-sliding activity of a kinesin-8 promotes spindle assembly and spindle-length control. Nat Cell Biol (2013) 1.14
Structure and activity of full-length formin mDia1. Cytoskeleton (Hoboken) (2012) 0.93
The Saccharomyces cerevisiae homolog of p24 is essential for maintaining the association of p150Glued with the dynactin complex. Genetics (2008) 0.92
A TOGL domain specifically targets yeast CLASP to kinetochores to stabilize kinetochore microtubules. J Cell Biol (2014) 0.81
Saccharomyces cerevisiae Kelch proteins and Bud14 protein form a stable 520-kDa formin regulatory complex that controls actin cable assembly and cell morphogenesis. J Biol Chem (2014) 0.79
Absolute quantification of somatic DNA alterations in human cancer. Nat Biotechnol (2012) 10.87
A mechanism linking extra centrosomes to chromosomal instability. Nature (2009) 9.45
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature (2005) 6.86
DNA breaks and chromosome pulverization from errors in mitosis. Nature (2012) 5.19
Tetraploidy, aneuploidy and cancer. Curr Opin Genet Dev (2007) 4.96
From polyploidy to aneuploidy, genome instability and cancer. Nat Rev Mol Cell Biol (2004) 4.72
An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol (2002) 4.52
Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance. Cell (2010) 4.37
Causes and consequences of aneuploidy in cancer. Nat Rev Genet (2012) 4.08
Yeast formins regulate cell polarity by controlling the assembly of actin cables. Nat Cell Biol (2002) 3.81
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes. Genes Dev (2008) 3.79
Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture. Cell (2004) 3.51
Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle. Nat Cell Biol (2006) 3.39
Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes. Nat Cell Biol (2002) 3.34
Genome-wide genetic analysis of polyploidy in yeast. Nature (2006) 2.85
A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin. Mol Biol Cell (2003) 2.77
Surfing on microtubule ends. Trends Cell Biol (2003) 2.61
Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation. Dev Cell (2004) 2.60
Determinants of S. cerevisiae dynein localization and activation: implications for the mechanism of spindle positioning. Curr Biol (2003) 2.56
Centrosomes and cilia in human disease. Trends Genet (2011) 2.42
The molecular function of Ase1p: evidence for a MAP-dependent midzone-specific spindle matrix. Microtubule-associated proteins. J Cell Biol (2003) 2.39
Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat Chem Biol (2010) 2.26
Polo-like kinase Cdc5 controls the local activation of Rho1 to promote cytokinesis. Science (2006) 1.73
Limiting the proliferation of polyploid cells. Cell (2007) 1.72
Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements. Genes Dev (2013) 1.61
A little CIN may cost a lot: revisiting aneuploidy and cancer. Curr Opin Genet Dev (2009) 1.57
Centrosomes and cancer: how cancer cells divide with too many centrosomes. Cancer Metastasis Rev (2009) 1.52
Mechanisms underlying the dual-mode regulation of microtubule dynamics by Kip3/kinesin-8. Mol Cell (2011) 1.51
The differential roles of budding yeast Tem1p, Cdc15p, and Bub2p protein dynamics in mitotic exit. Mol Biol Cell (2004) 1.49
Linking abnormal mitosis to the acquisition of DNA damage. J Cell Biol (2012) 1.48
Yeast formins Bni1 and Bnr1 utilize different modes of cortical interaction during the assembly of actin cables. Mol Biol Cell (2007) 1.46
Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors. Mol Cell Biol (2007) 1.38
Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells. J Clin Invest (2010) 1.38
Cell biology: aneuploidy and cancer. Nature (2007) 1.33
Defects arising from whole-genome duplications in Saccharomyces cerevisiae. Genetics (2004) 1.32
Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. J Clin Invest (2008) 1.29
Mechanisms for concentrating Rho1 during cytokinesis. Genes Dev (2009) 1.28
Processing, localization, and requirement of human separase for normal anaphase progression. Proc Natl Acad Sci U S A (2003) 1.24
Cancer genomes evolve by pulverizing single chromosomes. Cell (2011) 1.20
HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells. J Cell Biol (2010) 1.18
Microtubule-sliding activity of a kinesin-8 promotes spindle assembly and spindle-length control. Nat Cell Biol (2013) 1.14
Move in for the kill: motile microtubule regulators. Trends Cell Biol (2012) 1.08
Proteasomal degradation resolves competition between cell polarization and cellular wound healing. Cell (2012) 1.05
Inhibition of Cdc42 during mitotic exit is required for cytokinesis. J Cell Biol (2013) 0.98
Bub1, Sgo1, and Mps1 mediate a distinct pathway for chromosome biorientation in budding yeast. Mol Biol Cell (2011) 0.95
G1/S cyclin-dependent kinase regulates small GTPase Rho1p through phosphorylation of RhoGEF Tus1p in Saccharomyces cerevisiae. Mol Biol Cell (2008) 0.93
Regulation of the formin Bnr1 by septins anda MARK/Par1-family septin-associated kinase. Mol Biol Cell (2012) 0.89
Erratum: Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. Sci Data (2014) 0.83
APC and colon cancer: two hits for one. Nat Med (2007) 0.81
Mitotic spindle: laser microsurgery in yeast cells. Curr Biol (2004) 0.81
MEN signaling: daughter bound pole must escape her mother to be fully active. Dev Cell (2005) 0.78
Plugging the GAP between cell polarity and cell cycle. EMBO Rep (2008) 0.78
"Two" much of a good thing: telomere damage-induced genome doubling drives tumorigenesis. Cancer Cell (2012) 0.77
Symmetry breaking: scaffold plays matchmaker for polarity signaling proteins. Curr Biol (2008) 0.76
Cell biology. Aneuploidy in the balance. Science (2007) 0.76
David Pellman: Grasping the geometry of cancer. Interviewed by Caitlin Sedwick. J Cell Biol (2010) 0.75