Published in J Immunol on July 15, 2002
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol (2007) 3.51
The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models. Arthritis Res Ther (2004) 2.54
Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1. Am J Pathol (2005) 2.26
Bone marrow mesenchymal stem cells are abnormal in multiple myeloma. Leukemia (2007) 1.86
IL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils. PLoS Pathog (2012) 1.84
IL-17 family member cytokines: regulation and function in innate immunity. Cytokine Growth Factor Rev (2010) 1.76
Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines. Curr Rheumatol Rep (2007) 1.69
IL-17 family: cytokines, receptors and signaling. Cytokine (2013) 1.66
Signaling of interleukin-17 family cytokines in immunity and inflammation. Cell Signal (2010) 1.66
The octopus genome and the evolution of cephalopod neural and morphological novelties. Nature (2015) 1.39
IL-17 cytokines in immunity and inflammation. Emerg Microbes Infect (2013) 1.37
The influence of polymorphisms of interleukin-17A and interleukin-17F genes on the susceptibility to ulcerative colitis. J Clin Immunol (2007) 1.34
Up for Mischief? IL-17/Th17 in the tumour microenvironment. Oncogene (2010) 1.32
Genomic expression profiling of human inflammatory cardiomyopathy (DCMi) suggests novel therapeutic targets. J Mol Med (Berl) (2006) 1.12
Cardiovascular diabetology in the core of a novel interleukins classification: the bad, the good and the aloof. Cardiovasc Diabetol (2003) 1.09
Helper T cell differentiation enters a new era: le roi est mort; vive le roi! J Exp Med (2006) 1.03
Lamprey (Lethenteron japonicum) IL-17 upregulated by LPS-stimulation in the skin cells. Immunogenetics (2007) 1.01
Interleukin-17D mediates tumor rejection through recruitment of natural killer cells. Cell Rep (2014) 0.98
IL-17A and Th17 cells in lung inflammation: an update on the role of Th17 cell differentiation and IL-17R signaling in host defense against infection. Clin Dev Immunol (2013) 0.97
Transcriptional profiling of the murine cutaneous response during initial and subsequent infestations with Ixodes scapularis nymphs. Parasit Vectors (2012) 0.91
Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction. PLoS One (2012) 0.88
Interleukin 17A promotes gastric cancer invasiveness via NF-κB mediated matrix metalloproteinases 2 and 9 expression. PLoS One (2014) 0.88
A knowledgebase resource for interleukin-17 family mediated signaling. J Cell Commun Signal (2015) 0.87
Genetic polymorphisms of interleukin 17A and interleukin 17F and their association with inflammatory bowel disease in a Chinese Han population. Inflamm Res (2013) 0.87
Potential involvement of IL-17F in asthma. J Immunol Res (2014) 0.85
Interleukins and interleukin receptors in rheumatoid arthritis: Research, diagnostics and clinical implications. World J Orthop (2014) 0.82
IL-17F Induces CCL20 in Bronchial Epithelial Cells. J Allergy (Cairo) (2011) 0.81
Involvement of the IL-23/IL-17 axis and the Th17/Treg balance in the pathogenesis and control of autoimmune arthritis. Cytokine (2015) 0.81
Genetic determinants of P wave duration and PR segment. Circ Cardiovasc Genet (2014) 0.80
Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis. Mediators Inflamm (2015) 0.79
Interleukin and interleukin receptor gene polymorphisms in inflammatory bowel diseases susceptibility. World J Gastroenterol (2014) 0.79
MicroRNAs and other mechanisms regulate interleukin-17 cytokines and receptors. Front Biosci (Elite Ed) (2012) 0.79
Characterization of Lamprey IL-17 Family Members and Their Receptors. J Immunol (2015) 0.78
Gene expression profile analysis of Manila clam (Ruditapes philippinarum) hemocytes after a Vibrio alginolyticus challenge using an immune-enriched oligo-microarray. BMC Genomics (2014) 0.78
Antibody blockade of IL-17 family cytokines in immunity to acute murine oral mucosal candidiasis. J Leukoc Biol (2016) 0.78
IL-17B Can Impact on Endothelial Cellular Traits Linked to Tumour Angiogenesis. J Oncol (2010) 0.77
Therapeutic Potential of IL-17-Mediated Signaling Pathway in Autoimmune Liver Diseases. Mediators Inflamm (2015) 0.76
Investigation of Pathogenesis of H1N1 Influenza Virus and Swine Streptococcus suis Serotype 2 Co-Infection in Pigs by Microarray Analysis. PLoS One (2015) 0.76
Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphoma. J Clin Oncol (2006) 4.87
In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs. Mayo Clin Proc (2015) 4.70
Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood (2003) 4.19
NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J Biol Chem (2003) 3.98
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat Immunol (2010) 3.97
Modulation of hematopoietic stem cell homing and engraftment by CD26. Science (2004) 3.92
Umbilical cord blood transplantation: the first 25 years and beyond. Blood (2013) 2.79
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell (2008) 2.67
Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol (2007) 2.60
A noncytotoxic DsRed variant for whole-cell labeling. Nat Methods (2008) 2.34
The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair. Proc Natl Acad Sci U S A (2005) 2.15
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation. Cell Stem Cell (2013) 2.12
Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining. Proc Natl Acad Sci U S A (2010) 1.94
Rituximab, bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: safety, biomarker and pharmacokinetic analysis. Leuk Lymphoma (2006) 1.89
Immune responses in 4-1BB (CD137)-deficient mice. J Immunol (2002) 1.74
Metnase mediates chromosome decatenation in acute leukemia cells. Blood (2009) 1.74
Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist. Transfusion (2005) 1.71
Drug Repurposing from an Academic Perspective. Drug Discov Today Ther Strateg (2011) 1.68
SDF-1/CXCL12 enhances survival and chemotaxis of murine embryonic stem cells and production of primitive and definitive hematopoietic progenitor cells. Stem Cells (2005) 1.68
More forks on the road to replication stress recovery. J Mol Cell Biol (2011) 1.64
Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells. J Immunol (2002) 1.63
Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells. J Immunol (2006) 1.56
The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression. Proc Natl Acad Sci U S A (2002) 1.52
Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice. Stem Cells Dev (2007) 1.50
Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability. Blood (2007) 1.48
Placebo-controlled phase III trial of patient-specific immunotherapy with mitumprotimut-T and granulocyte-macrophage colony-stimulating factor after rituximab in patients with follicular lymphoma. J Clin Oncol (2009) 1.46
New approaches for improving engraftment after cord blood transplantation. Biol Blood Marrow Transplant (2009) 1.46
Synthetic lethality: exploiting the addiction of cancer to DNA repair. Blood (2011) 1.42
Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking. Am J Respir Crit Care Med (2010) 1.42
Cell surface peptidase CD26/DPPIV mediates G-CSF mobilization of mouse progenitor cells. Blood (2003) 1.40
P21waf-1-Chk1 pathway monitors G1 phase microtubule integrity and is crucial for restriction point transition. Cell Cycle (2002) 1.40
The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation. Nucleic Acids Res (2008) 1.38
SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse. Blood (2010) 1.36
Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow. Stem Cells (2008) 1.33
Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin. Stem Cells (2007) 1.30
Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis. Blood (2009) 1.29
Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines. Blood (2002) 1.26
Upregulation of nascent mitochondrial biogenesis in mouse hematopoietic stem cells parallels upregulation of CD34 and loss of pluripotency: a potential strategy for reducing oxidative risk in stem cells. Cell Cycle (2010) 1.25
Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancer. Cancer Res (2007) 1.24
Metnase promotes restart and repair of stalled and collapsed replication forks. Nucleic Acids Res (2010) 1.21
BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production. Blood (2004) 1.20
Flt3 ligand and the Flt3 receptor regulate hematopoietic cell migration by modulating the SDF-1alpha(CXCL12)/CXCR4 axis. Blood (2004) 1.20
Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells. PLoS One (2009) 1.20
Epigenetic regulation of NANOG by miR-302 cluster-MBD2 completes induced pluripotent stem cell reprogramming. Stem Cells (2013) 1.19
SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress. Stem Cells (2014) 1.19
Implications of DPP4 modification of proteins that regulate stem/progenitor and more mature cell types. Blood (2013) 1.18
In vivo DPP-4 inhibition to enhance engraftment of single-unit cord blood transplants in adults with hematological malignancies. Stem Cells Dev (2013) 1.17
Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist. Support Cancer Ther (2004) 1.16
Enhanced green fluorescent protein is a nearly ideal long-term expression tracer for hematopoietic stem cells, whereas DsRed-express fluorescent protein is not. Stem Cells (2006) 1.15
Improved Peptide and Protein Torsional Energetics with the OPLSAA Force Field. J Chem Theory Comput (2015) 1.13
Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34(+) NOD/SCID-repopulating cells. Exp Hematol (2008) 1.13
Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. J Immunol (2012) 1.13
The chemokine CXCL14 (BRAK) stimulates activated NK cell migration: implications for the downregulation of CXCL14 in malignancy. Exp Hematol (2006) 1.12
Sirtuin 1, stem cells, aging, and stem cell aging. Curr Opin Hematol (2008) 1.11
Murine embryonic stem cells secrete cytokines/growth modulators that enhance cell survival/anti-apoptosis and stimulate colony formation of murine hematopoietic progenitor cells. Stem Cells (2005) 1.09
Impaired development of human Th1 cells in patients with deficient expression of STAT4. Blood (2009) 1.07
Metnase/SETMAR: a domesticated primate transposase that enhances DNA repair, replication, and decatenation. Genetica (2010) 1.06
Mechanisms of leukemia translocations. Curr Opin Hematol (2008) 1.06
Mouse hematopoietic cell-targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging-like phenotype. Blood (2012) 1.05
Phase II clinical trial of interleukin-12 in patients with relapsed and refractory non-Hodgkin's lymphoma and Hodgkin's disease. Clin Cancer Res (2004) 1.05
CD26 is essential for normal G-CSF-induced progenitor cell mobilization as determined by CD26-/- mice. Exp Hematol (2003) 1.05
Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation. Blood (2009) 1.04
Macrophage colony-stimulating factor drives cord blood monocyte differentiation into IL-10(high)IL-12absent dendritic cells with tolerogenic potential. J Immunol (2005) 1.04
SIRT1 deficiency downregulates PTEN/JNK/FOXO1 pathway to block reactive oxygen species-induced apoptosis in mouse embryonic stem cells. Stem Cells Dev (2011) 1.02
Targeting the transposase domain of the DNA repair component Metnase to enhance chemotherapy. Cancer Res (2012) 1.01
Identification of a human B-cell/myeloid common progenitor by the absence of CXCR4. Blood (2005) 1.00
Enhancement of cell survival by stromal cell-derived factor-1/CXCL12 involves activation of CREB and induction of Mcl-1 and c-Fos in factor-dependent human cell line MO7e. Stem Cells Dev (2004) 1.00
Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis. Blood (2003) 1.00
Expression levels of the human DNA repair protein metnase influence lentiviral genomic integration. Biochimie (2008) 0.99
Ex vivo rapamycin treatment of human cord blood CD34+ cells enhances their engraftment of NSG mice. Blood Cells Mol Dis (2011) 0.99
AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice. Exp Hematol (2008) 0.98
The homeoprotein Hex is required for hemangioblast differentiation. Blood (2003) 0.98
Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression. Mol Cell Biol (2009) 0.97
Depsipeptide (FK228) preferentially induces apoptosis in BCR/ABL-expressing cell lines and cells from patients with chronic myelogenous leukemia in blast crisis. Stem Cells Dev (2007) 0.97
STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis. Blood (2011) 0.97
PARP1 is required for chromosomal translocations. Blood (2013) 0.96
Transforming growth factor-{beta}1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/CXCL12. Blood (2005) 0.96
Muscle-derived Gr1(dim)CD11b(+) cells enhance neovascularization in an ischemic hind limb mouse model. Blood (2010) 0.95
CCR5 ligands modulate CXCL12-induced chemotaxis, adhesion, and Akt phosphorylation of human cord blood CD34+ cells. J Immunol (2009) 0.95
Primary pancreatic follicle center-derived lymphoma masquerading as carcinoma. Gastroenterol Hepatol (N Y) (2011) 0.95
CD26 inhibition and hematopoiesis: a novel approach to enhance transplantation. Front Biosci (2008) 0.94
Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45. Blood Cells Mol Dis (2006) 0.94
Superoxide flashes, reactive oxygen species, and the mitochondrial permeability transition pore: potential implications for hematopoietic stem cell function. Curr Opin Hematol (2011) 0.94
TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC. Blood (2011) 0.93
Transplantation of mouse HSCs genetically modified to express a CD4-restricted TCR results in long-term immunity that destroys tumors and initiates spontaneous autoimmunity. J Clin Invest (2010) 0.93
Protein phosphatase 2A plays an important role in stromal cell-derived factor-1/CXC chemokine ligand 12-mediated migration and adhesion of CD34+ cells. J Immunol (2007) 0.93
The DDN catalytic motif is required for Metnase functions in non-homologous end joining (NHEJ) repair and replication restart. J Biol Chem (2014) 0.92
Immune regulatory cells in umbilical cord blood and their potential roles in transplantation tolerance. Crit Rev Oncol Hematol (2010) 0.92
P-selectin enhances generation of CD14+CD16+ dendritic-like cells and inhibits macrophage maturation from human peripheral blood monocytes. J Immunol (2003) 0.92
Modulation of cord blood CD8+ T-cell effector differentiation by TGF-beta1 and 4-1BB costimulation. Blood (2004) 0.91
Redox regulation of the embryonic stem cell transcription factor oct-4 by thioredoxin. Stem Cells (2004) 0.91
SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl. Blood (2006) 0.91
5-Aminoimidazole-4-carboxyamide ribonucleoside induces G(1)/S arrest and Nanog downregulation via p53 and enhances erythroid differentiation. Stem Cells (2012) 0.90
Tip110 maintains expression of pluripotent factors in and pluripotency of human embryonic stem cells. Stem Cells Dev (2012) 0.90
4-1BB ligand stimulation enhances myeloid dendritic cell maturation from human umbilical cord blood CD34+ progenitor cells. J Hematother Stem Cell Res (2002) 0.89