Published in J Biol Chem on July 09, 2002
Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium. Proc Natl Acad Sci U S A (2007) 1.85
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels. Proc Natl Acad Sci U S A (2004) 1.11
Insight into the self-association of key enzymes from pathogenic species. Eur Biophys J (2005) 1.09
Protein dynamics explain the allosteric behaviors of hemoglobin. Biochim Biophys Acta (2008) 1.07
Macromolecular neutron crystallography at the Protein Crystallography Station (PCS). Acta Crystallogr D Biol Crystallogr (2010) 1.05
Computing phenomenologic Adair-Klotz constants from microscopic MWC parameters. BMC Syst Biol (2009) 0.99
Modulation of reactivity and conformation within the T-quaternary state of human hemoglobin: the combined use of mutagenesis and sol-gel encapsulation. Biochemistry (2006) 0.98
Molecular dynamics simulations of hemoglobin A in different states and bound to DPG: effector-linked perturbation of tertiary conformations and HbA concerted dynamics. Biophys J (2007) 0.94
Molecular controls of the oxygenation and redox reactions of hemoglobin. Antioxid Redox Signal (2013) 0.92
Interfacial and distal-heme pocket mutations exhibit additive effects on the structure and function of hemoglobin. Biochemistry (2008) 0.89
Effector-induced structural fluctuation regulates the ligand affinity of an allosteric protein: binding of inositol hexaphosphate has distinct dynamic consequences for the T and R states of hemoglobin. Biochemistry (2008) 0.88
New look at hemoglobin allostery. Chem Rev (2015) 0.87
Experiments on Hemoglobin in Single Crystals and Silica Gels Distinguish among Allosteric Models. Biophys J (2015) 0.86
Liganded hemoglobin structural perturbations by the allosteric effector L35. Biophys J (2004) 0.84
Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions. Blood Transfus (2010) 0.83
Differential control of heme reactivity in alpha and beta subunits of hemoglobin: a combined Raman spectroscopic and computational study. J Am Chem Soc (2014) 0.83
Heme reactivity is uncoupled from quaternary structure in gel-encapsulated hemoglobin: a resonance Raman spectroscopic study. J Am Chem Soc (2012) 0.83
Insights into the solution structure of human deoxyhemoglobin in the absence and presence of an allosteric effector. Biochemistry (2007) 0.83
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels. Protein Sci (2006) 0.82
Reverse engineering the cooperative machinery of human hemoglobin. PLoS One (2013) 0.82
Experimental basis for a new allosteric model for multisubunit proteins. Proc Natl Acad Sci U S A (2014) 0.82
An investigation of the distal histidyl hydrogen bonds in oxyhemoglobin: effects of temperature, pH, and inositol hexaphosphate. Biochemistry (2010) 0.82
Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling. ACS Chem Biol (2014) 0.81
Quaternary structures of intermediately ligated human hemoglobin a and influences from strong allosteric effectors: resonance Raman investigation. Biophys J (2005) 0.81
Solution structure and dynamics of human hemoglobin in the carbonmonoxy form. Biochemistry (2013) 0.81
Structure of fully liganded Hb ζ2β2s trapped in a tense conformation. Acta Crystallogr D Biol Crystallogr (2013) 0.78
Oxidative effects of gemfibrozil on anion influx and metabolism in normal and Beta-thalassemic erythrocytes: physiological implications. J Membr Biol (2008) 0.77
From protein structure to function via single crystal optical spectroscopy. Front Mol Biosci (2015) 0.77
Steric factors moderate conformational fluidity and contribute to the high proton sensitivity of Root effect hemoglobins. Biochim Biophys Acta (2011) 0.76
Oximetry with the NMR signals of hemoglobin Val E11 and Tyr C7. Eur J Appl Physiol (2009) 0.75
Protonation states of histidine and other key residues in deoxy normal human adult hemoglobin by neutron protein crystallography. Acta Crystallogr D Biol Crystallogr (2010) 0.75
Modulation of Hemoglobin Dynamics by an Allosteric Effector. Protein Sci (2016) 0.75
Phthalide Derivatives from Angelica Sinensis Decrease Hemoglobin Oxygen Affinity: A New Allosteric-Modulating Mechanism and Potential Use as 2,3-BPG Functional Substitutes. Sci Rep (2017) 0.75
Using the MWC model to describe heterotropic interactions in hemoglobin. PLoS One (2017) 0.75
Haem conformation of amphibian nytrosylhaemoglobins detected by XANES spectroscopy. Eur Phys J E Soft Matter (2005) 0.75
Involvement of a bifunctional fatty-acyl desaturase in the biosynthesis of the silkmoth, Bombyx mori, sex pheromone. Proc Natl Acad Sci U S A (2004) 1.28
Clotrimazole binds to heme and enhances heme-dependent hemolysis: proposed antimalarial mechanism of clotrimazole. J Biol Chem (2001) 1.03
Pyrene is highly emissive when attached to the RNA duplex but not to the DNA duplex: the structural basis of this difference. Nucleic Acids Res (2005) 1.02
Neutralization of toxic heme by Plasmodium falciparum histidine-rich protein 2. J Biochem (2003) 1.02
Functional characterization of the Bombyx mori fatty acid transport protein (BmFATP) within the silkmoth pheromone gland. J Biol Chem (2008) 0.98
Two-metal ion, Ni(II) and Cu(II), binding alpha-helical coiled coil peptide. J Am Chem Soc (2004) 0.95
R-state haemoglobin with low oxygen affinity: crystal structures of deoxy human and carbonmonoxy horse haemoglobin bound to the effector molecule L35. J Mol Biol (2005) 0.92
Sex pheromone production in the silkworm, Bombyx mori, is mediated by store-operated Ca2+ channels. Biosci Biotechnol Biochem (2007) 0.88
Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure. J Am Coll Cardiol (2008) 0.88
Structural and oxygen binding properties of dimeric horse myoglobin. Dalton Trans (2012) 0.86
Effect of antifungal azoles on the heme detoxification system of malarial parasite. J Biochem (2002) 0.85
The cooperativity of human fetal and adult hemoglobins is optimized: a consideration based on the effectiveness of the Bohr shift. Zoolog Sci (2003) 0.83
Semihemoglobins, high oxygen affinity dimeric forms of human hemoglobin respond efficiently to allosteric effectors without forming tetramers. J Biol Chem (2004) 0.83
Erythrocytes with T-state-stabilized hemoglobin as a therapeutic tool for postischemic liver dysfunction. Antioxid Redox Signal (2006) 0.82
Molecular insight into intrinsic heme distortion in ligand binding in hemoprotein. Biochemistry (2010) 0.82
A new paramagnetic intermediate formed during the reaction of nitrite with deoxyhemoglobin. J Am Chem Soc (2011) 0.82
Contribution of cooperativity and the Bohr effect to efficient oxygen transport by hemoglobins from five mammalian species. Zoolog Sci (2006) 0.81
The global allostery model of hemoglobin: an allosteric mechanism involving homotropic and heterotropic interactions. C R Biol (2003) 0.81
Allosteric effectors influence the tetramer stability of both R- and T-states of hemoglobin A. J Biol Chem (2006) 0.81
Effect of heme modification on oxygen affinity of myoglobin and equilibrium of the acid-alkaline transition in metmyoglobin. J Am Chem Soc (2010) 0.80
Creation of a type 1 blue copper site within a de novo coiled-coil protein scaffold. J Am Chem Soc (2010) 0.80
ADP reduces the oxygen-binding affinity of a sensory histidine kinase, FixL: the possibility of an enhanced reciprocating kinase reaction. Proc Natl Acad Sci U S A (2004) 0.80
Interaction of gymnemic acid with cyclodextrins analyzed by isothermal titration calorimetry, NMR and dynamic light scattering. FEBS J (2005) 0.80
The uncoupling of oxygen sensing, phosphorylation signalling and transcriptional activation in oxygen sensor FixL and FixJ mutants. Mol Microbiol (2003) 0.80
Effect of reversed heme orientation on circular dichroism and cooperative oxygen binding of human adult hemoglobin. Biochemistry (2007) 0.79
Creation of a binuclear purple copper site within a de novo coiled-coil protein. Biochemistry (2012) 0.79
Circular dichroism of hemoglobin and myoglobin. Chirality (2014) 0.79
Oxygen equilibrium and EPR studies on alpha1beta1 hemoglobin dimer. J Biochem (2004) 0.79
Significance of affinity and cooperativity in oxygen binding to hemoglobin of horse fetal and maternal blood. Zoolog Sci (2003) 0.79
Chemical identification and ethological function of soldier-specific secretion in Japanese subterranean termite Reticulitermes speratus (Rhinotermitidae). Biosci Biotechnol Biochem (2011) 0.79
How does hemoglobin generate such diverse functionality of physiological relevance? Biochim Biophys Acta (2013) 0.78
Hb KOCHI [beta141(H19)Leu-->Val (g.1404 C-->G); 144-->146(HC1-3)Lys-Tyr-His-->0 (g.1413 A-->T)]: a new variant with increased oxygen affinity. Hemoglobin (2005) 0.78
The Bombyx mori sex pheromone biosynthetic pathway is not mediated by cAMP. J Insect Physiol (2007) 0.78
A cysteine residue near the propionate side chain of heme is the radical site in ascorbate peroxidase. FEBS J (2007) 0.78
Near-UV circular dichroism and UV resonance Raman spectra of individual tryptophan residues in human hemoglobin and their changes upon the quaternary structure transition. Biochemistry (2012) 0.78
Functional evaluation of iron oxypyriporphyrin in protein heme pocket. Inorg Chem (2008) 0.78
Description of hemoglobin oxygenation under universal solution conditions by a global allostery model with a single adjustable parameter. Biophys Chem (2002) 0.78
Method for determination of association and dissociation rate constants of reversible bimolecular reactions by isothermal titration calorimeters. Anal Chem (2007) 0.77
The swinging movement of the distal histidine residue and the autoxidation reaction for midge larval hemoglobins. Eur J Biochem (2003) 0.77
Liposome-encapsulated hemoglobin alleviates hearing loss after transient cochlear ischemia and reperfusion in the gerbil. Artif Organs (2011) 0.77
The roles of conserved amino acids on substrate binding and conformational integrity of ClpB N-terminal domain. Biochemistry (2006) 0.77
Influence of allosteric effectors and temperature on oxygen binding properties and the Bohr effect of bovine hemoglobin. Zoolog Sci (2006) 0.76
Differences in coordination states of substituted tyrosine residues and quaternary structures among hemoglobin M probed by resonance Raman spectroscopy. J Biol Inorg Chem (2009) 0.76
Selective formation of AAB- and ABC-type heterotrimeric alpha-helical coiled coils. Chemistry (2004) 0.76
Iron hemiporphycene as a functional prosthetic group for myoglobin. Inorg Chem (2003) 0.76
Solution structure and stability of the DNA undecamer duplexes containing oxanine mismatch. Nucleic Acids Res (2011) 0.75
T-quaternary structure of oxy human adult hemoglobin in the presence of two allosteric effectors, L35 and IHP. Biochim Biophys Acta (2011) 0.75
Significance of the molecular shape of iron corrphycene in a protein pocket. Inorg Chem (2006) 0.75
Heme orientational disorder in human adult hemoglobin reconstituted with a ring fluorinated heme and its functional consequences. Biochem Biophys Res Commun (2007) 0.75
Electronic control of discrimination between O2 and CO in myoglobin lacking the distal histidine residue. Inorg Chem (2013) 0.75
Change of the isoelectric point of hemoglobin at the air/water interface probed by the orientational flip-flop of water molecules. Phys Chem Chem Phys (2017) 0.75
Hb Buzen [beta138(H16)Ala --> Thr (g.1395 G -->A)]: a new beta chain variant. Hemoglobin (2003) 0.75
Identification of an antiamyloidogenic substance from mulberry leaves. Neuroreport (2009) 0.75
Relationship between oxygen affinity and autoxidation of myoglobin. Inorg Chem (2012) 0.75
UV luminescent organic-capped ZnO quantum dots synthesized by alkoxide hydrolysis with dilute water. J Colloid Interface Sci (2010) 0.75
Oxygenation properties of extracellular giant hemoglobin from Oligobrachia mashikoi. Biochem Biophys Res Commun (2007) 0.75
Formation of a fairly stable diazoate intermediate of 5-methyl-2'-deoxycytidine by HNO2 and NO, and its implication to a novel mutation mechanism in CpG site. Bioorg Med Chem (2002) 0.75
Relationship between the electron density of the heme Fe atom and the vibrational frequencies of the Fe-bound carbon monoxide in myoglobin. Inorg Chem (2013) 0.75
Nitration of 2'-deoxyguanosine by a NO/O2 gas mixture: identification and characterization of N2-nitro-2'-deoxyguanosine. Org Lett (2003) 0.75
Involvement of propionate side chains of the heme in circular dichroism of myoglobin: experimental and theoretical analyses. J Phys Chem B (2015) 0.75
Functional tolerance of Streptomyces subtilisin inhibitor toward conformational and stability changes caused by single-point mutations in the hydrophobic core. J Biochem (2002) 0.75