Published in Genes Chromosomes Cancer on August 01, 2002
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet (2007) 11.62
The European dimension for the mouse genome mutagenesis program. Nat Genet (2004) 3.84
The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. Cell (2003) 2.71
Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nat Genet (2003) 2.21
Mutant mitochondrial elongation factor G1 and combined oxidative phosphorylation deficiency. N Engl J Med (2004) 2.17
Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice. Hum Mol Genet (2008) 2.00
A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans. PLoS Biol (2007) 1.77
Apc mice: models, modifiers and mutants. Pathol Res Pract (2008) 1.59
Mutation of C20orf7 disrupts complex I assembly and causes lethal neonatal mitochondrial disease. Am J Hum Genet (2008) 1.58
Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes. J Clin Invest (2008) 1.50
Gene identification for the cblD defect of vitamin B12 metabolism. N Engl J Med (2008) 1.46
An update on the genetics of colorectal cancer. Hum Mol Genet (2004) 1.39
The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression. Gastroenterology (2009) 1.28
CABAS: a freely available PC program for fitting calibration curves in chromosome aberration dosimetry. Radiat Prot Dosimetry (2007) 1.25
Mutations of the PU.1 Ets domain are specifically associated with murine radiation-induced, but not human therapy-related, acute myeloid leukaemia. Oncogene (2005) 1.19
Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice. Cancer Res (2004) 1.19
Histone-modifier gene expression profiles are associated with pathological and clinical outcomes in human breast cancer. Anticancer Res (2011) 1.15
Refining molecular analysis in the pathways of colorectal carcinogenesis. Clin Gastroenterol Hepatol (2005) 1.14
R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion. Nat Cell Biol (2007) 1.12
Behavior, movements, and demographics of rabid raccoons in Ontario, Canada: management implications. J Wildl Dis (2006) 1.09
Genetic polymorphisms in the DNA repair genes XRCC1, XRCC2 and XRCC3 and risk of breast cancer in Cyprus. Breast Cancer Res Treat (2008) 1.09
Association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations. J Am Soc Nephrol (2007) 1.07
Chromosomes 6 and 18 induce neoplastic suppression in epithelial ovarian cancer cells. Int J Cancer (2009) 1.02
The elimination of raccoon rabies from Wolfe Island, Ontario: animal density and movements. J Wildl Dis (2007) 1.02
Effective and structural connectivity in the human auditory cortex. J Neurosci (2008) 1.01
Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer. Gastroenterology (2006) 0.98
The expression of gene transcripts of telomere-associated genes in human breast cancer: correlation with clinico-pathological parameters and clinical outcome. Breast Cancer Res Treat (2007) 0.97
G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes. Diabetes (2008) 0.96
A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitivity in a patient with xeroderma pigmentosum. J Med Genet (2009) 0.96
European rational approach for the genetics of diabetic complications--EURAGEDIC: patient populations and strategy. Nephrol Dial Transplant (2007) 0.96
Mapping of a candidate colorectal cancer tumor-suppressor gene to a 900-kilobase region on the short arm of chromosome 8. Genes Chromosomes Cancer (2004) 0.95
Function and connectivity in human primary auditory cortex: a combined fMRI and DTI study at 3 Tesla. Cereb Cortex (2006) 0.94
Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice. Proc Natl Acad Sci U S A (2005) 0.93
Oral rapamycin reduces tumour burden and vascularization in Lkb1(+/-) mice. J Pathol (2009) 0.93
APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'. Hum Mol Genet (2006) 0.92
Positioning of human chromosomes in murine cell hybrids according to synteny. Chromosoma (2008) 0.91
Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population. Breast Cancer Res Treat (2009) 0.91
DNA-repair genetic polymorphisms and risk of breast cancer in Cyprus. Breast Cancer Res Treat (2008) 0.90
Mutations within Wnt pathway genes in sporadic colorectal cancers and cell lines. Int J Cancer (2006) 0.90
Activation of AKT and nuclear accumulation of wild type TP53 and MDM2 in anal squamous cell carcinoma. Int J Cancer (2007) 0.88
The mRNA expression of inhibitors of DNA binding-1 and -2 is associated with advanced tumour stage and adverse clinical outcome in human breast cancer. Anticancer Res (2013) 0.88
DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid. Inflamm Bowel Dis (2014) 0.87
In vivo biostability of a poly(carbonate-urea)urethane graft. Biomaterials (2003) 0.86
Defects in the adherens junction complex (E-cadherin/ β-catenin) in inflammatory bowel disease. Cell Tissue Res (2014) 0.86
Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion. Mol Cancer (2013) 0.85
Intestinal tumours induced in Apc(Min/+) mice by X-rays and neutrons. Int J Radiat Biol (2011) 0.84
Osteogenic tumours in Lkb1-deficient mice. Exp Mol Pathol (2008) 0.83
Macrophages from BALB/c and CBA/Ca mice differ in their cellular responses to Streptococcus pneumoniae. J Leukoc Biol (2009) 0.83
A novel exon duplication event leading to a truncating germ-line mutation of the APC gene in a familial adenomatous polyposis family. Fam Cancer (2006) 0.83
Management of colorectal cancer: a role for genetics in prevention and treatment? Pathol Res Pract (2008) 0.82
The fetal mouse is a sensitive genotoxicity model that exposes lentiviral-associated mutagenesis resulting in liver oncogenesis. Mol Ther (2012) 0.82
Dietary cystine level affects metabolic rate and glycaemic control in adult mice. J Nutr Biochem (2011) 0.82
A mortality gene(s) for the human adenocarcinoma line HeLa maps to a 130-kb region of human chromosome 4q22-q23. Neoplasia (2002) 0.82
Low Serum Levels of MicroRNA-19 Are Associated with a Stricturing Crohn's Disease Phenotype. Inflamm Bowel Dis (2015) 0.82
Microsatellite instability in radiation-induced murine tumours; influence of tumour type and radiation quality. Int J Radiat Biol (2010) 0.82
A chromosome 3-encoded repressor of the human telomerase reverse transcriptase (hTERT) gene controls the state of hTERT chromatin. Cancer Res (2003) 0.81
NCF1 (p47phox) and ncf1 pseudogenes are not associated with inflammatory bowel disease. Inflamm Bowel Dis (2004) 0.81
A mitotic recombination map proximal to the APC locus on chromosome 5q and assessment of influences on colorectal cancer risk. BMC Med Genet (2009) 0.81
HSP27 expression in primary colorectal cancers is dependent on mutation of KRAS and PI3K/AKT activation status and is independent of TP53. Exp Mol Pathol (2012) 0.81
Elevation of WNT5A expression in polyp formation in Lkb1+/- mice and Peutz-Jeghers syndrome. J Pathol (2011) 0.80
Pregnancy does not influence colonic polyp multiplicity but may modulate upper gastrointestinal disease in patients with FAP. J Med Genet (2007) 0.80
Intestinal fibrosis in Crohn's disease: role of microRNAs as fibrogenic modulators, serum biomarkers, and therapeutic targets. Inflamm Bowel Dis (2015) 0.79
Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs. Mutagenesis (2011) 0.79
In vitro stability of a novel compliant poly(carbonate-urea)urethane to oxidative and hydrolytic stress. J Biomed Mater Res (2002) 0.79
Functional evidence for a squamous cell carcinoma mortality gene(s) on human chromosome 4. Oncogene (2002) 0.79
Adenoma multiplicity in irradiated Apc(Min) mice is modified by chromosome 16 segments from BALB/c. Cancer Res (2003) 0.79
A mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutation. PLoS One (2012) 0.78
The combination of nebulized sodium cromoglycate and salbutamol in the treatment of moderate-to-severe asthma in children. Pediatr Allergy Immunol (2002) 0.78
An activity associated with human chromosome 21 permits nuclear colocalization of the adenovirus E1B-55K and E4orf6 proteins and promotes viral late gene expression. J Virol (2003) 0.78
A major breakpoint cluster domain in murine radiation-induced acute myeloid leukemia. Mol Carcinog (2002) 0.77
There is no correlation between c-Myc mRNA expression and telomerase activity in human breast cancer. Int Semin Surg Oncol (2004) 0.77
Direct single gene mutational events account for radiation-induced intestinal adenoma yields in Apc(Min/+) mice. Radiat Res (2005) 0.77
The rate of X-ray-induced DNA double-strand break repair in the embryonic mouse brain is unaffected by exposure to 50 Hz magnetic fields. Int J Radiat Biol (2015) 0.77
Non-apoptotic function of caspases in a cellular model of hydrogen peroxide-associated colitis. J Cell Mol Med (2013) 0.77
The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression. J Carcinog (2004) 0.77
A two-mutation model of radiation-induced acute myeloid leukemia using historical mouse data. Radiat Environ Biophys (2010) 0.76
Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice. PLoS One (2009) 0.76
Repeated H2 O2 exposure drives cell cycle progression in an in vitro model of ulcerative colitis. J Cell Mol Med (2013) 0.76
A mouse model for osseous heteroplasia. PLoS One (2012) 0.76
Positive association to IgE levels and a physical map of the 13q14 atopy locus. Eur J Hum Genet (2002) 0.76
Internal dosimetry and tritium--the ICRP position. J Radiol Prot (2008) 0.75
Is telomerase reactivation associated with the down-regulation of TGF beta receptor-II expression in human breast cancer? Cancer Cell Int (2003) 0.75
The value of physical examination in conjunction with a survey for identifying youth pitchers with arm pain. Iowa Orthop J (2011) 0.75
Mechanistic and genetic studies of radiation tumorigenesis in the mouse--implications for low dose risk estimation. J Radiol Prot (2002) 0.75
How radiosensitive are the developing embryo and fetus? Ann ICRP (2003) 0.75