Published in Chromosoma on July 24, 2008
Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts. Genome Biol (2010) 1.38
Non-random organization of the Biomphalaria glabrata genome in interphase Bge cells and the spatial repositioning of activated genes in cells co-cultured with Schistosoma mansoni. Int J Parasitol (2010) 1.02
Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues. BMC Cell Biol (2012) 0.89
HAC stability in murine cells is influenced by nuclear localization and chromatin organization. BMC Cell Biol (2009) 0.87
Hierarchical radial and polar organisation of chromosomes in human sperm. Chromosome Res (2012) 0.82
Tissue-of-origin-specific gene repositioning in breast and prostate cancer. Histochem Cell Biol (2016) 0.82
The nucleus introduced. Cold Spring Harb Perspect Biol (2011) 0.78
Spatial Genome Organization and Its Emerging Role as a Potential Diagnosis Tool. Front Genet (2016) 0.75
Progeria Research Day at Brunel University. Nucleus (2011) 0.75
Systems-level chromosomal parameters represent a suprachromosomal basis for the non-random chromosomal arrangement in human interphase nuclei. Sci Rep (2016) 0.75
A method for simultaneously delineating multiple targets in 3D-FISH using limited channels, lasers, and fluorochromes. Eur Biophys J (2013) 0.75
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
Beyond the sequence: cellular organization of genome function. Cell (2007) 10.32
Nuclear organization of the genome and the potential for gene regulation. Nature (2007) 8.22
Differences in the localization and morphology of chromosomes in the human nucleus. J Cell Biol (1999) 6.35
Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions. Nat Rev Genet (2007) 6.14
Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps. Science (2005) 5.47
Transcriptional repression mediated by repositioning of genes to the nuclear lamina. Nature (2008) 4.92
The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells. Hum Mol Genet (2001) 4.79
Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol (2005) 4.33
Chromosome territories--a functional nuclear landscape. Curr Opin Cell Biol (2006) 3.82
Recruitment to the nuclear periphery can alter expression of genes in human cells. PLoS Genet (2008) 3.75
A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence. J Cell Biol (2008) 3.39
Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells. Chromosome Res (2001) 2.89
Tissue-specific spatial organization of genomes. Genome Biol (2004) 2.57
Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates. Proc Natl Acad Sci U S A (2002) 2.53
Cell biology: chromosome territories. Nature (2007) 2.47
Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH. J Cell Biol (2002) 2.40
Non-random radial arrangements of interphase chromosome territories: evolutionary considerations and functional implications. Mutat Res (2002) 2.24
Nuclear organization of mammalian genomes. Polar chromosome territories build up functionally distinct higher order compartments. J Cell Biol (1999) 2.19
Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories. Hum Genet (1985) 2.14
Inheritance of gene density-related higher order chromatin arrangements in normal and tumor cell nuclei. J Cell Biol (2003) 2.12
Spatial genome organization in the formation of chromosomal translocations. Semin Cancer Biol (2006) 2.12
Coregulated human globin genes are frequently in spatial proximity when active. J Cell Biol (2006) 2.12
Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells. Proc Natl Acad Sci U S A (1977) 1.97
Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes. Chromosome Res (2003) 1.94
Spatial organization of active and inactive genes and noncoding DNA within chromosome territories. J Cell Biol (2002) 1.92
Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts. Curr Biol (2000) 1.84
Common themes and cell type specific variations of higher order chromatin arrangements in the mouse. BMC Cell Biol (2005) 1.75
A genetic analysis of chromosome territory looping: diverse roles for distal regulatory elements. Chromosome Res (2003) 1.67
Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP. Genes Dev (2008) 1.62
Locus-specific and activity-independent gene repositioning during early tumorigenesis. J Cell Biol (2008) 1.56
The genome and the nucleus: a marriage made by evolution. Genome organisation and nuclear architecture. Chromosoma (2005) 1.45
Radial chromatin positioning is shaped by local gene density, not by gene expression. Chromosoma (2007) 1.45
Primary laminopathy fibroblasts display altered genome organization and apoptosis. Aging Cell (2007) 1.43
Size-dependent positioning of human chromosomes in interphase nuclei. Biophys J (2000) 1.43
Construction of mouse A9 clones containing a single human chromosome tagged with neomycin-resistance gene via microcell fusion. Jpn J Cancer Res (1989) 1.40
Gene silencing at the nuclear periphery. FEBS J (2007) 1.36
Human acrocentric chromosomes with transcriptionally silent nucleolar organizer regions associate with nucleoli. EMBO J (2001) 1.35
Movement of the X chromosome in epilepsy. Science (1988) 1.30
Topology of genes and nontranscribed sequences in human interphase nuclei. Exp Cell Res (2004) 1.29
Spatial genome organization during T-cell differentiation. Cytogenet Genome Res (2004) 1.22
Construction and characterization of a highly stable human: rodent monochromosomal hybrid panel for genetic complementation and genome mapping studies. Cytogenet Cell Genet (1995) 1.21
The nuclear lamina. Both a structural framework and a platform for genome organization. FEBS J (2007) 1.17
Association of pKi-67 with satellite DNA of the human genome in early G1 cells. Chromosome Res (1998) 1.16
Alteration of chromosome positioning during adipocyte differentiation. J Cell Sci (2004) 1.13
Evolutionarily conserved, cell type and species-specific higher order chromatin arrangements in interphase nuclei of primates. Chromosoma (2007) 1.13
Alterations to nuclear architecture and genome behavior in senescent cells. Ann N Y Acad Sci (2007) 1.11
Nuclear organization of centromeric domains is not perturbed by inhibition of histone deacetylases. Chromosome Res (2004) 1.11
Non-random chromosome positioning in mammalian sperm nuclei, with migration of the sex chromosomes during late spermatogenesis. J Cell Sci (2005) 1.07
Chromosome territory reorganization in a human disease with altered DNA methylation. Proc Natl Acad Sci U S A (2007) 1.06
Microcell-mediated chromosome transfer (MMCT): small cells with huge potential. Mamm Genome (2003) 1.03
The architecture of interphase chromosomes and gene positioning are altered by changes in DNA methylation and histone acetylation. J Cell Sci (2002) 1.03
The manipulation of chromosomes by mankind: the uses of microcell-mediated chromosome transfer. Chromosoma (2005) 1.02
Local gene density predicts the spatial position of genetic loci in the interphase nucleus. Exp Cell Res (2005) 1.00
Inter- and intra-specific gene-density-correlated radial chromosome territory arrangements are conserved in Old World monkeys. Cytogenet Genome Res (2005) 0.99
Artificially introduced aneuploid chromosomes assume a conserved position in colon cancer cells. PLoS One (2007) 0.97
The architecture of chicken chromosome territories changes during differentiation. BMC Cell Biol (2004) 0.96
Perturbation of mammalian cell division. II. Studies on the isolation and characterization of human mini segregant cells. J Cell Sci (1975) 0.90
Chromosome territory positioning of conserved homologous chromosomes in different primate species. Chromosoma (2006) 0.85
Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations. Biochem Soc Trans (2005) 0.84
Identification of human tumour suppressor genes by monochromosome transfer: rapid growth-arrest response mapped to 9p21 is mediated solely by the cyclin-D-dependent kinase inhibitor gene, CDKN2A (p16INK4A). Carcinogenesis (1996) 0.84
Tumor suppressor genes studied by cell hybridization and chromosome transfer. FASEB J (1993) 0.83
Changes in chromosome positioning may contribute to the development of diseases related to X-chromosome aneuploidy. J Cell Physiol (2007) 0.81
Transcription-dependent spatial arrangements of CFTR and conserved adjacent loci are not conserved in human and murine nuclei. Chromosoma (2008) 0.80
Human monochromosome hybrid cell panel characterized by FISH in the JCRB/HSRRB. Chromosome Res (2000) 0.80
Complementation of mismatch repair gene defects by chromosome transfer. Mutat Res (1998) 0.79
The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. Cell (2003) 2.71
Mutant mitochondrial elongation factor G1 and combined oxidative phosphorylation deficiency. N Engl J Med (2004) 2.17
Mutation of C20orf7 disrupts complex I assembly and causes lethal neonatal mitochondrial disease. Am J Hum Genet (2008) 1.58
Gene identification for the cblD defect of vitamin B12 metabolism. N Engl J Med (2008) 1.46
The genome and the nucleus: a marriage made by evolution. Genome organisation and nuclear architecture. Chromosoma (2005) 1.45
Primary laminopathy fibroblasts display altered genome organization and apoptosis. Aging Cell (2007) 1.43
FISH glossary: an overview of the fluorescence in situ hybridization technique. Biotechniques (2008) 1.41
Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts. Genome Biol (2010) 1.38
The spatial repositioning of adipogenesis genes is correlated with their expression status in a porcine mesenchymal stem cell adipogenesis model system. Chromosoma (2009) 1.20
Histone-modifier gene expression profiles are associated with pathological and clinical outcomes in human breast cancer. Anticancer Res (2011) 1.15
Alterations to nuclear architecture and genome behavior in senescent cells. Ann N Y Acad Sci (2007) 1.11
Genetic polymorphisms in the DNA repair genes XRCC1, XRCC2 and XRCC3 and risk of breast cancer in Cyprus. Breast Cancer Res Treat (2008) 1.09
Non-random chromosome positioning in mammalian sperm nuclei, with migration of the sex chromosomes during late spermatogenesis. J Cell Sci (2005) 1.07
Chromosomes 6 and 18 induce neoplastic suppression in epithelial ovarian cancer cells. Int J Cancer (2009) 1.02
Non-random organization of the Biomphalaria glabrata genome in interphase Bge cells and the spatial repositioning of activated genes in cells co-cultured with Schistosoma mansoni. Int J Parasitol (2010) 1.02
The manipulation of chromosomes by mankind: the uses of microcell-mediated chromosome transfer. Chromosoma (2005) 1.02
Association of adipogenic genes with SC-35 domains during porcine adipogenesis. Chromosome Res (2010) 0.98
The expression of gene transcripts of telomere-associated genes in human breast cancer: correlation with clinico-pathological parameters and clinical outcome. Breast Cancer Res Treat (2007) 0.97
Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells. Genome Biol (2011) 0.96
A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitivity in a patient with xeroderma pigmentosum. J Med Genet (2009) 0.96
Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes. PLoS Genet (2010) 0.95
Mapping of a candidate colorectal cancer tumor-suppressor gene to a 900-kilobase region on the short arm of chromosome 8. Genes Chromosomes Cancer (2004) 0.95
Will all scientists working on snails and the diseases they transmit please stand up? PLoS Negl Trop Dis (2012) 0.94
Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population. Breast Cancer Res Treat (2009) 0.91
DNA-repair genetic polymorphisms and risk of breast cancer in Cyprus. Breast Cancer Res Treat (2008) 0.90
The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer. Cell Mol Biol Lett (2013) 0.89
Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues. BMC Cell Biol (2012) 0.89
The mRNA expression of inhibitors of DNA binding-1 and -2 is associated with advanced tumour stage and adverse clinical outcome in human breast cancer. Anticancer Res (2013) 0.88
Revised karyotyping and gene mapping of the Biomphalaria glabrata embryonic (Bge) cell line. Int J Parasitol (2008) 0.87
Exploring the effects of a dysfunctional nuclear matrix. Biochem Soc Trans (2008) 0.86
Exploring the relationship between interphase gene positioning, transcriptional regulation and the nuclear matrix. Biochem Soc Trans (2010) 0.86
Nuclear motors and nuclear structures containing A-type lamins and emerin: is there a functional link? Biochem Soc Trans (2008) 0.84
Progeria, the nucleolus and farnesyltransferase inhibitors. Biochem Soc Trans (2010) 0.83
A mortality gene(s) for the human adenocarcinoma line HeLa maps to a 130-kb region of human chromosome 4q22-q23. Neoplasia (2002) 0.82
Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells. Mutat Res (2013) 0.82
The fetal mouse is a sensitive genotoxicity model that exposes lentiviral-associated mutagenesis resulting in liver oncogenesis. Mol Ther (2012) 0.82
A chromosome 3-encoded repressor of the human telomerase reverse transcriptase (hTERT) gene controls the state of hTERT chromatin. Cancer Res (2003) 0.81
Towards a Drosophila model of Hutchinson-Gilford progeria syndrome. Biochem Soc Trans (2008) 0.81
Lamins A and C are present in the nuclei of early porcine embryos, with lamin A being distributed in large intranuclear foci. Chromosome Res (2007) 0.81
FISH on chromosomes derived from the snail model organism Biomphalaria glabrata. Methods Mol Biol (2010) 0.80
Functional evidence for a squamous cell carcinoma mortality gene(s) on human chromosome 4. Oncogene (2002) 0.79
Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs. Mutagenesis (2011) 0.79
Fluorescence in situ hybridization on early porcine embryos. Methods Mol Biol (2010) 0.78
An activity associated with human chromosome 21 permits nuclear colocalization of the adenovirus E1B-55K and E4orf6 proteins and promotes viral late gene expression. J Virol (2003) 0.78
There is no correlation between c-Myc mRNA expression and telomerase activity in human breast cancer. Int Semin Surg Oncol (2004) 0.77
The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression. J Carcinog (2004) 0.77
Genomic imbalances are confined to non-proliferating cells in paediatric patients with acute myeloid leukaemia and a normal or incomplete karyotype. PLoS One (2011) 0.75
Is telomerase reactivation associated with the down-regulation of TGF beta receptor-II expression in human breast cancer? Cancer Cell Int (2003) 0.75
Fluorescence in situ hybridization on DNA halo preparations and extended chromatin fibres. Methods Mol Biol (2010) 0.75
Corrigendum: Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nat Commun (2017) 0.75
Functional evidence from microcell-mediated chromosome transfer of myeloid leukemia suppressor genes on human chromosomes 7 and 11. Genes Chromosomes Cancer (2002) 0.75
P14ARF is down-regulated during tumour progression and predicts the clinical outcome in human breast cancer. Anticancer Res (2013) 0.75