|
1
|
Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation.
|
Am J Respir Crit Care Med
|
2007
|
2.17
|
|
2
|
Role of alphavbeta6 integrin in acute biliary fibrosis.
|
Hepatology
|
2007
|
1.80
|
|
3
|
Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.
|
Am J Pathol
|
2007
|
1.79
|
|
4
|
Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis.
|
Am J Respir Crit Care Med
|
2007
|
1.79
|
|
5
|
Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice.
|
J Cell Sci
|
2009
|
1.75
|
|
6
|
Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms.
|
Circ Res
|
2008
|
1.73
|
|
7
|
Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism.
|
Cancer Res
|
2008
|
1.73
|
|
8
|
Function-blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes.
|
J Biol Chem
|
2004
|
1.72
|
|
9
|
Stromal features are predictive of disease mortality in oral cancer patients.
|
J Pathol
|
2011
|
1.54
|
|
10
|
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
|
Am J Respir Crit Care Med
|
2014
|
1.54
|
|
11
|
Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).
|
Am J Pathol
|
2009
|
1.50
|
|
12
|
Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6.
|
Mol Cell Biol
|
2007
|
1.41
|
|
13
|
The coagulation system contributes to alphaVbeta6 integrin expression and liver fibrosis induced by cholestasis.
|
Am J Pathol
|
2010
|
1.21
|
|
14
|
The alpha(v)beta6 integrin receptor for Foot-and-mouth disease virus is expressed constitutively on the epithelial cells targeted in cattle.
|
J Gen Virol
|
2005
|
1.20
|
|
15
|
Structure-function analysis of Arg-Gly-Asp helix motifs in alpha v beta 6 integrin ligands.
|
J Biol Chem
|
2007
|
1.18
|
|
16
|
Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β.
|
Am J Pathol
|
2012
|
1.03
|
|
17
|
Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice.
|
Am J Respir Crit Care Med
|
2009
|
1.01
|
|
18
|
Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapy.
|
Cancer Res
|
2006
|
1.01
|
|
19
|
Overexpression of the alphavbeta6 integrin in endometrial cancer.
|
Appl Immunohistochem Mol Morphol
|
2008
|
1.01
|
|
20
|
Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis.
|
J Pathol
|
2010
|
1.00
|
|
21
|
Effect of wound type on Smad 2 and 4 translocation.
|
Invest Ophthalmol Vis Sci
|
2005
|
0.99
|
|
22
|
Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2.
|
Cancer Res
|
2014
|
0.97
|
|
23
|
Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion.
|
Cancer Res
|
2006
|
0.95
|
|
24
|
Proteomic identification of lynchpin urokinase plasminogen activator receptor protein interactions associated with epithelial cancer malignancy.
|
J Proteome Res
|
2007
|
0.91
|
|
25
|
Role of integrin alphav beta6 in acute lung injury induced by Pseudomonas aeruginosa.
|
Infect Immun
|
2008
|
0.87
|
|
26
|
α(V)β(6) integrin expression is induced in the POET and Pten(pc-/-) mouse models of prostatic inflammation and prostatic adenocarcinoma.
|
Am J Transl Res
|
2012
|
0.87
|
|
27
|
Blocking TGFβ via Inhibition of the αvβ6 Integrin: A Possible Therapy for Systemic Sclerosis Interstitial Lung Disease.
|
Int J Rheumatol
|
2011
|
0.87
|
|
28
|
Connective tissue growth factor and integrin αvβ6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice.
|
Hepatology
|
2015
|
0.86
|
|
29
|
Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis.
|
Am J Physiol Lung Cell Mol Physiol
|
2014
|
0.83
|
|
30
|
Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010.
|
Proc Am Thorac Soc
|
2011
|
0.83
|
|
31
|
A cell-free electrochemiluminescence assay for measuring beta1-integrin-ligand interactions.
|
Anal Biochem
|
2002
|
0.76
|
|
32
|
Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents.
|
Bioorg Med Chem Lett
|
2003
|
0.75
|
|
33
|
Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.
|
JCI Insight
|
2017
|
0.75
|