Published in Mol Vis on January 15, 2009
Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. Mol Vis (2009) 1.44
Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors. Mol Vis (2011) 1.00
Development of diagnostic and treatment strategies for glaucoma through understanding and modification of scleral and lamina cribrosa connective tissue. Cell Tissue Res (2013) 0.92
Expression profile of the matricellular protein osteopontin in primary open-angle glaucoma and the normal human eye. Invest Ophthalmol Vis Sci (2011) 0.87
Differential gene expression in glaucoma. Cold Spring Harb Perspect Med (2014) 0.81
Tools and resources for analyzing gene expression changes in glaucomatous neurodegeneration. Exp Eye Res (2015) 0.79
Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells. BMC Ophthalmol (2014) 0.79
Integrins in trabecular meshwork and optic nerve head: possible association with the pathogenesis of glaucoma. Biomed Res Int (2013) 0.78
The role of epigenetics in the fibrotic processes associated with glaucoma. J Ophthalmol (2014) 0.77
Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma. Cell Cycle (2016) 0.76
The stereotypical molecular cascade in neovascular age-related macular degeneration: the role of dynamic reciprocity. Eye (Lond) (2015) 0.75
Bioinformatics analysis to identify the differentially expressed genes of glaucoma. Mol Med Rep (2015) 0.75
Life under pressure: The role of ocular cribriform cells in preventing glaucoma. Exp Eye Res (2016) 0.75
Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells. PLoS One (2016) 0.75
Major review: Molecular genetics of primary open-angle glaucoma. Exp Eye Res (2017) 0.75
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89
Identifying biological themes within lists of genes with EASE. Genome Biol (2003) 31.72
Number of people with glaucoma worldwide. Br J Ophthalmol (1996) 14.31
Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma. Science (2007) 7.55
The impact of ocular blood flow in glaucoma. Prog Retin Eye Res (2002) 5.76
The optic nerve head as a biomechanical structure: a new paradigm for understanding the role of IOP-related stress and strain in the pathophysiology of glaucomatous optic nerve head damage. Prog Retin Eye Res (2005) 4.76
Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons. Invest Ophthalmol Vis Sci (2000) 4.19
periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol (2005) 2.94
Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport. Invest Ophthalmol Vis Sci (1980) 2.55
The optic nerve head in glaucoma: role of astrocytes in tissue remodeling. Prog Retin Eye Res (2000) 2.44
Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk. J Biol Chem (2003) 2.25
Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic properties. Eur J Biochem (1990) 2.13
Understanding mechanisms of pressure-induced optic nerve damage. Prog Retin Eye Res (2005) 1.79
Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model. Invest Ophthalmol Vis Sci (2007) 1.73
Estimation of the binding force of the collagen molecule-decorin core protein complex in collagen fibril. J Biomech (2005) 1.70
Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo. Kidney Int (2004) 1.44
Predominant expression of human zic in cerebellar granule cell lineage and medulloblastoma. Cancer Res (1996) 1.36
Connective tissue growth factor is a regulator for fibrosis in human chronic pancreatitis. Ann Surg (1999) 1.34
The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia. J Biol Chem (2003) 1.33
Type VI collagen induces cardiac myofibroblast differentiation: implications for postinfarction remodeling. Am J Physiol Heart Circ Physiol (2005) 1.31
Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells. J Appl Physiol (1985) (2004) 1.31
Expression of bone morphogenetic proteins (BMP), BMP receptors, and BMP associated proteins in human trabecular meshwork and optic nerve head cells and tissues. Mol Vis (2002) 1.28
Increased collagen type III synthesis by fibroblasts isolated from strictures of patients with Crohn's disease. Gastroenterology (1992) 1.27
The optic nerve head in glaucomatous optic neuropathy. Arch Ophthalmol (1997) 1.26
Human tissue inhibitor of metalloproteinases 3 interacts with both the N- and C-terminal domains of gelatinases A and B. Regulation by polyanions. J Biol Chem (1999) 1.23
Periostin and periostin-like factor in the human heart: possible therapeutic targets. Cardiovasc Pathol (2006) 1.22
In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury. J Biol Chem (2004) 1.20
Bone morphogenetic protein-1/tolloid-related metalloproteinases process osteoglycin and enhance its ability to regulate collagen fibrillogenesis. J Biol Chem (2004) 1.16
The interaction of dystrophin with beta-dystroglycan is regulated by tyrosine phosphorylation. Cell Signal (2001) 1.13
Cell culture of the human lamina cribrosa. Invest Ophthalmol Vis Sci (1988) 1.10
A hyaluronan binding link protein gene family whose members are physically linked adjacent to chondroitin sulfate proteoglycan core protein genes: the missing links. J Biol Chem (2003) 1.09
Beta ig-h3 interacts directly with biglycan and decorin, promotes collagen VI aggregation, and participates in ternary complexing with these macromolecules. J Biol Chem (2006) 1.08
Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells. Glia (2005) 1.07
Neurotrophin and neurotrophin receptor expression by cells of the human lamina cribrosa. Invest Ophthalmol Vis Sci (2001) 1.05
Glaucoma: changes in extracellular matrix in the optic nerve head. Ann Med (1993) 1.02
Induction of HLA-DR expression in human lamina cribrosa astrocytes by cytokines and simulated ischemia. Invest Ophthalmol Vis Sci (2001) 1.02
Clinical significance of thrombospondin 1 expression in hepatocellular carcinoma. Clin Cancer Res (2004) 1.01
Pleiotrophin exhibits a trophic effect on survival of dopaminergic neurons in vitro. Eur J Neurosci (2003) 1.00
Use of a mathematical model to estimate stress and strain during elevated pressure induced lamina cribrosa deformation. Curr Eye Res (2001) 0.97
Gene expression profiling of epithelial ovarian tumours correlated with malignant potential. Mol Cancer (2004) 0.94
Collagen type IV gene expression in human optic nerve heads with primary open angle glaucoma. Exp Eye Res (1994) 0.92
Hyaluronic acid in the normal and glaucomatous optic nerve. Exp Eye Res (1997) 0.91
Collagen type I mRNA levels in cultured human lamina cribrosa cells: effects of elevated hydrostatic pressure. Exp Eye Res (1993) 0.91
The association between changes in skin echogenicity and the fibroblast production of biglycan and versican in systemic sclerosis. Clin Exp Rheumatol (2002) 0.90
Hypoxic induction of cox-2 regulates proliferation of human pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol (2002) 0.90
Transcript profiling of periodontal fibroblasts and osteoblasts. J Periodontol (2005) 0.87
Differential expression of neural cell adhesion molecule isoforms in normal and glaucomatous human optic nerve heads. Brain Res Mol Brain Res (1999) 0.81
A subtractive approach to characterize genes with regionalized expression in the gliogenic ventral neuroepithelium: identification of chick sulfatase 1 as a new oligodendrocyte lineage gene. Mol Cell Neurosci (2004) 0.80
Distribution of N-cadherin in human cerebral cortex during prenatal development. Histochem Cell Biol (2004) 0.78
A forensic path to RGC-5 cell line identification: lessons learned. Invest Ophthalmol Vis Sci (2013) 3.31
Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration. Vis Neurosci (2005) 2.86
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma. J Clin Invest (2011) 2.25
TGFbeta2-induced changes in human trabecular meshwork: implications for intraocular pressure. Invest Ophthalmol Vis Sci (2006) 2.02
Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma. Invest Ophthalmol Vis Sci (2007) 1.97
Noninvasive measurement of rodent intraocular pressure with a rebound tonometer. Invest Ophthalmol Vis Sci (2005) 1.75
The role of steroids in outflow resistance. Exp Eye Res (2008) 1.71
Rodent models for glaucoma retinopathy and optic neuropathy. J Glaucoma (2007) 1.70
Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma. J Clin Invest (2011) 1.69
Bone morphogenetic proteins and their receptors in the eye. Exp Biol Med (Maywood) (2007) 1.65
Transforming growth factor-beta induces extracellular matrix protein cross-linking lysyl oxidase (LOX) genes in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 1.60
Adenoviral gene transfer of active human transforming growth factor-{beta}2 elevates intraocular pressure and reduces outflow facility in rodent eyes. Invest Ophthalmol Vis Sci (2009) 1.56
Existence of the canonical Wnt signaling pathway in the human trabecular meshwork. Invest Ophthalmol Vis Sci (2012) 1.53
Tissue transglutaminase expression and activity in normal and glaucomatous human trabecular meshwork cells and tissues. Invest Ophthalmol Vis Sci (2008) 1.49
Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma. J Clin Invest (2012) 1.44
Glaucoma-causing myocilin mutants require the Peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure. Hum Mol Genet (2007) 1.44
Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure. J Clin Invest (2008) 1.39
Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro. Mol Vis (2005) 1.28
Expression of bone morphogenetic proteins (BMP), BMP receptors, and BMP associated proteins in human trabecular meshwork and optic nerve head cells and tissues. Mol Vis (2002) 1.28
Assessment of aqueous humor dynamics in the mouse by a novel method of constant-flow infusion. Invest Ophthalmol Vis Sci (2011) 1.27
Cross-linked actin networks (CLANs) in the trabecular meshwork of the normal and glaucomatous human eye in situ. Invest Ophthalmol Vis Sci (2008) 1.27
Dexamethasone inhibition of trabecular meshwork cell phagocytosis and its modulation by glucocorticoid receptor beta. Exp Eye Res (2006) 1.25
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death. Neurobiol Dis (2012) 1.25
Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-beta. Invest Ophthalmol Vis Sci (2005) 1.17
Pigment epithelium-derived factor protects retinal ganglion cells. BMC Neurosci (2007) 1.17
Importance of quantitative PCR primer location for short interfering RNA efficacy determination. Anal Biochem (2005) 1.14
FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor beta and glucocorticoid responsiveness. Invest Ophthalmol Vis Sci (2008) 1.11
Worldwide geographical distribution of ophthalmology publications. Int Ophthalmol (2008) 1.11
Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damage. Invest Ophthalmol Vis Sci (2005) 1.08
Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells. Glia (2005) 1.07
Connective tissue growth factor is increased in pseudoexfoliation glaucoma. Invest Ophthalmol Vis Sci (2011) 1.06
Role of TGFbeta/Smad signaling in gremlin induction of human trabecular meshwork extracellular matrix proteins. Invest Ophthalmol Vis Sci (2011) 1.05
Human optic nerve head astrocytes as a target for endothelin-1. Invest Ophthalmol Vis Sci (2002) 1.04
Exon-level expression profiling of ocular tissues. Exp Eye Res (2013) 1.04
Soluble CD44 is cytotoxic to trabecular meshwork and retinal ganglion cells in vitro. Invest Ophthalmol Vis Sci (2005) 1.02
Quantitative proteomics: TGFβ₂ signaling in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 1.02
Semiquantitative optic nerve grading scheme for determining axonal loss in experimental optic neuropathy. Invest Ophthalmol Vis Sci (2006) 1.02
Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma. J Clin Invest (2014) 1.00
Focus on molecules: gremlin. Exp Eye Res (2007) 0.99
Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head. J Glaucoma (2004) 0.99
Transforming growth factor-beta2 utilizes the canonical Smad-signaling pathway to regulate tissue transglutaminase expression in human trabecular meshwork cells. Exp Eye Res (2011) 0.99
A novel antioxidant function for the tumor-suppressor gene p53 in the retinal ganglion cell. Invest Ophthalmol Vis Sci (2008) 0.98
Gene expression profile of the adult human retinal ganglion cell layer. Mol Vis (2006) 0.97
The role of TGF-β2 and bone morphogenetic proteins in the trabecular meshwork and glaucoma. J Ocul Pharmacol Ther (2014) 0.97
Expression of matrix metalloproteinases and their inhibitors in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2003) 0.97
A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. PLoS One (2013) 0.97
A key role for calpains in retinal ganglion cell death. Invest Ophthalmol Vis Sci (2007) 0.96
Mutant human myocilin induces strain specific differences in ocular hypertension and optic nerve damage in mice. Exp Eye Res (2012) 0.96
Progressive morphological changes and impaired retinal function associated with temporal regulation of gene expression after retinal ischemia/reperfusion injury in mice. Mol Neurodegener (2013) 0.95
Acute effects of glaucoma medications on rat intraocular pressure. Exp Eye Res (2005) 0.95
Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model. BMC Neurosci (2007) 0.94
Heat shock protein 90 is an essential molecular chaperone for nuclear transport of glucocorticoid receptor beta. Invest Ophthalmol Vis Sci (2006) 0.94
Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells. Exp Eye Res (2012) 0.94
Effect of immunomodulation with anti-CD40L antibody on adenoviral-mediated transgene expression in mouse anterior segment. Mol Vis (2008) 0.92
Inducers of cross-linked actin networks in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2011) 0.92
Aqueous outflow-enhancing effect of tert-butylhydroquinone: involvement of AP-1 activation and MMP-3 expression. Invest Ophthalmol Vis Sci (2003) 0.91
Comparison of expression profile of neurotrophins and their receptors in primary and transformed rat retinal ganglion cells. Mol Vis (2007) 0.90
Transforming growth factor-β2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway. Mol Vis (2011) 0.89
Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo. J Neurochem (2007) 0.89
Spliceosome protein (SRp) regulation of glucocorticoid receptor isoforms and glucocorticoid response in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2012) 0.89
Focus on molecules: SFRP1. Exp Eye Res (2010) 0.89
Fibulin-5 distribution in human eyes: relevance to age-related macular degeneration. Exp Eye Res (2006) 0.89
Cellular fibronectin expression in human trabecular meshwork and induction by transforming growth factor-β2. Invest Ophthalmol Vis Sci (2013) 0.88
Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders. Mol Vis (2010) 0.87
Altered endothelin-1 vasoreactivity in patients with untreated normal-pressure glaucoma. Invest Ophthalmol Vis Sci (2006) 0.87
Increased expression of serum amyloid A in glaucoma and its effect on intraocular pressure. Invest Ophthalmol Vis Sci (2008) 0.87
Proteomic similarities in steroid responsiveness in normal and glaucomatous trabecular meshwork cells. Mol Vis (2012) 0.87
Glutamate stimulates neurotrophin expression in cultured Müller cells. Brain Res Mol Brain Res (2003) 0.87
Perfusion-cultured bovine anterior segments as an ex vivo model for studying glucocorticoid-induced ocular hypertension and glaucoma. Invest Ophthalmol Vis Sci (2011) 0.86
Characterization of a spontaneously immortalized bovine trabecular meshwork cell line. Exp Eye Res (2012) 0.86
Smad3 is necessary for transforming growth factor-beta2 induced ocular hypertension in mice. Exp Eye Res (2013) 0.85
The effect of postmortem time on the RNA quality of human ocular tissues. Mol Vis (2013) 0.85
Protein macroarray profiling of serum autoantibodies in pseudoexfoliation glaucoma. Invest Ophthalmol Vis Sci (2010) 0.85
Involvement of AP-1 in interleukin-1alpha-stimulated MMP-3 expression in human trabecular meshwork cells. Invest Ophthalmol Vis Sci (2003) 0.85
Anterior juxtascleral delivery of anecortave acetate in eyes with primary open-angle glaucoma: a pilot investigation. Am J Ophthalmol (2008) 0.85