Published in JAMA on July 22, 2002
Discontinuation of statins in routine care settings: a cohort study. Ann Intern Med (2013) 5.87
Why don't diabetes patients achieve recommended risk factor targets? Poor adherence versus lack of treatment intensification. J Gen Intern Med (2008) 3.99
Factors affecting therapeutic compliance: A review from the patient's perspective. Ther Clin Risk Manag (2008) 3.75
Primary medication non-adherence: analysis of 195,930 electronic prescriptions. J Gen Intern Med (2010) 3.57
Coronary Heart Disease Mortality Declines in the United States From 1979 Through 2011: Evidence for Stagnation in Young Adults, Especially Women. Circulation (2015) 3.56
New prescription medication gaps: a comprehensive measure of adherence to new prescriptions. Health Serv Res (2009) 2.63
The significance of compliance and persistence in the treatment of diabetes, hypertension and dyslipidaemia: a review. Int J Clin Pract (2007) 2.51
Increasing levels of restriction in pharmacoepidemiologic database studies of elderly and comparison with randomized trial results. Med Care (2007) 2.31
Depression and medication adherence in outpatients with coronary heart disease: findings from the Heart and Soul Study. Arch Intern Med (2005) 2.28
The Lifestyle Interventions and Independence for Elders Study: design and methods. J Gerontol A Biol Sci Med Sci (2011) 2.26
Impact of a prescription copayment increase on lipid-lowering medication adherence in veterans. Circulation (2009) 2.06
The impracticality of biomedical rejuvenation therapies: translational and pharmacological barriers. Rejuvenation Res (2014) 2.02
Suboptimal statin adherence and discontinuation in primary and secondary prevention populations. J Gen Intern Med (2004) 2.01
Measuring concurrent adherence to multiple related medications. Am J Manag Care (2009) 1.88
Medication adherence: a call for action. Am Heart J (2011) 1.85
Cardiovascular health disparities: a systematic review of health care interventions. Med Care Res Rev (2007) 1.83
Lipid profile components and risk of ischemic stroke: the Northern Manhattan Study (NOMAS). Arch Neurol (2009) 1.74
Association of clinical symptomatic hypoglycemia with cardiovascular events and total mortality in type 2 diabetes: a nationwide population-based study. Diabetes Care (2012) 1.67
Predictors of nonadherence to statins: a systematic review and meta-analysis. Ann Pharmacother (2010) 1.66
Falling into the coverage gap: Part D drug costs and adherence for Medicare Advantage prescription drug plan beneficiaries with diabetes. Health Serv Res (2009) 1.66
Secondary preventive medication persistence and adherence 1 year after stroke. Neurology (2011) 1.62
Adherence to cardiovascular disease medications: does patient-provider race/ethnicity and language concordance matter? J Gen Intern Med (2010) 1.59
Effect of exposure to evidence-based pharmacotherapy on outcomes after acute myocardial infarction in older adults. J Am Geriatr Soc (2012) 1.58
Antimuscarinic persistence patterns in newly treated patients with overactive bladder: a retrospective comparative analysis. Int Urogynecol J (2013) 1.57
The clinical implications of ageing for rational drug therapy. Eur J Clin Pharmacol (2008) 1.56
Effects of increased patient cost sharing on socioeconomic disparities in health care. J Gen Intern Med (2008) 1.56
The 2003 Canadian recommendations for dyslipidemia management: revisions are needed. CMAJ (2005) 1.49
Trends in adherence to secondary prevention medications in elderly post-myocardial infarction patients. Pharmacoepidemiol Drug Saf (2008) 1.45
Defining an evidence-based cutpoint for medication adherence in heart failure. Am Heart J (2008) 1.44
Foot pain in rheumatoid arthritis prevalence, risk factors and management: an epidemiological study. Clin Rheumatol (2009) 1.42
Developments in post-marketing comparative effectiveness research. Clin Pharmacol Ther (2007) 1.42
Standardizing terminology and definitions of medication adherence and persistence in research employing electronic databases. Med Care (2013) 1.38
Predictors of medication adherence using a multidimensional adherence model in patients with heart failure. J Card Fail (2008) 1.37
Unintentional non-adherence to chronic prescription medications: how unintentional is it really? BMC Health Serv Res (2012) 1.37
Adherence to cardioprotective medications and mortality among patients with diabetes and ischemic heart disease. BMC Cardiovasc Disord (2006) 1.35
Racial differences in medication adherence: A cross-sectional study of Medicare enrollees. Am J Geriatr Pharmacother (2010) 1.30
Persistence and determinants of statin therapy among middle-aged patients for primary and secondary prevention. Br J Clin Pharmacol (2005) 1.29
Hospital discharge instructions: comprehension and compliance among older adults. J Gen Intern Med (2014) 1.27
Bisphosphonates in the management of postmenopausal osteoporosis--optimizing efficacy in clinical practice. Clin Interv Aging (2008) 1.22
How do we improve patient compliance and adherence to long-term statin therapy? Curr Atheroscler Rep (2013) 1.20
Racial and ethnic disparities in cardiovascular medication use among older adults in the United States. Pharmacoepidemiol Drug Saf (2010) 1.19
Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training. Compr Physiol (2013) 1.17
Relationship between adherence to hepatitis C virus therapy and virologic outcomes: a cohort study. Ann Intern Med (2011) 1.17
Long term persistence with statin treatment in daily medical practice. Heart (2004) 1.13
Associations of kidney function with cardiovascular medication use after myocardial infarction. Clin J Am Soc Nephrol (2008) 1.12
Patients' perspectives on nonadherence to statin therapy: a focus-group study. Perm J (2010) 1.12
Interventions to improve adherence to lipid lowering medication. Cochrane Database Syst Rev (2004) 1.12
How should we measure medication adherence in clinical trials and practice? Ther Clin Risk Manag (2007) 1.12
Study protocol: the Adherence and Intensification of Medications (AIM) study--a cluster randomized controlled effectiveness study. Trials (2010) 1.11
Reducing Medication Costs to Prevent Cardiovascular Disease: A Community Guide Systematic Review. Prev Chronic Dis (2015) 1.11
Impact of better adherence to statin agents in the primary prevention of coronary artery disease. Eur J Clin Pharmacol (2009) 1.11
Impact of adherence to statins on coronary artery disease in primary prevention. Br J Clin Pharmacol (2007) 1.11
Association between adherence to statin therapy and lipid control in Hong Kong Chinese patients at high risk of coronary heart disease. Br J Clin Pharmacol (2004) 1.10
Prevalence and correlates of self-reported medication non-adherence among older adults with coronary heart disease, diabetes mellitus, and/or hypertension. Res Social Adm Pharm (2013) 1.10
Use of statins and beta-blockers after acute myocardial infarction according to income and education. J Epidemiol Community Health (2007) 1.09
Adherence to cardiovascular medications: lessons learned and future directions. Prog Cardiovasc Dis (2013) 1.08
Adherence to statin or aspirin or both in patients with established cardiovascular disease: exploring healthy behaviour vs. drug effects and 10-year follow-up of outcome. Br J Clin Pharmacol (2008) 1.06
Provider-patient adherence dialogue in HIV care: results of a multisite study. AIDS Behav (2013) 1.06
Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease. Eur J Clin Pharmacol (2005) 1.05
Medication adherence and cognition. Medical, personal and economic factors influence level of adherence in older adults. Geriatrics (2006) 1.05
Patient compliance based on genetic medicine: a literature review. J Community Genet (2013) 1.04
Benefits of statin therapy and compliance in high risk cardiovascular patients. Vasc Health Risk Manag (2010) 1.03
Drug development and use in the elderly: search for the right dose and dosing regimen (Parts I and II). Br J Clin Pharmacol (2004) 1.02
Cost-related nonadherence by medication type among Medicare Part D beneficiaries with diabetes. Med Care (2013) 1.02
Medication adherence after myocardial infarction: a long way left to go. J Gen Intern Med (2008) 1.01
Impact of prescription size on statin adherence and cholesterol levels. BMC Health Serv Res (2007) 1.00
Adherence with single-pill amlodipine/atorvastatin vs a two-pill regimen. Vasc Health Risk Manag (2008) 1.00
The association between compliance and persistence with bisphosphonate therapy and fracture risk: a review. BMC Musculoskelet Disord (2007) 0.99
Age-specific nonpersistence of endocrine therapy in postmenopausal patients diagnosed with hormone receptor-positive breast cancer: a TEAM study analysis. Oncologist (2011) 0.99
Lifestyle and psychosocial risk factors predict non-adherence to medication. Ann Behav Med (2010) 0.98
Primary adherence to controller medications for asthma is poor. Ann Am Thorac Soc (2015) 0.98
Cholesterol treatment with statins: who is left out and who makes it to goal? BMC Health Serv Res (2010) 0.97
Regimen complexity and medication nonadherence in elderly patients. Ther Clin Risk Manag (2009) 0.96
Mortality and recurrence risk in relation to the use of lipid-lowering drugs in a prospective breast cancer patient cohort. PLoS One (2013) 0.96
Do patients' expectations influence their use of medications? Qualitative study. Can Fam Physician (2008) 0.96
Adherence to beta-blocker therapy under drug cost-sharing in patients with and without acute myocardial infarction. Am J Manag Care (2007) 0.96
Improving the validity of determining medication adherence from electronic health record medications orders. J Am Med Inform Assoc (2011) 0.95
Kidney function and long-term medication adherence after myocardial infarction in the elderly. Clin J Am Soc Nephrol (2011) 0.95
Medication adherence among rural, low-income hypertensive adults: a randomized trial of a multimedia community-based intervention. Am J Health Promot (2011) 0.95
Elderly patients' adherence to statin therapy. JAMA (2002) 0.94
Family practice patients' adherence to statin medications. Can Fam Physician (2007) 0.94
Can improved prescription medication labeling influence adherence to chronic medications? An evaluation of the Target pharmacy label. J Gen Intern Med (2009) 0.93
Facilitating Clinical Research through the Health Information Exchange: Lipid Control as an Example. AMIA Annu Symp Proc (2010) 0.93
Adherence to alendronate in male veterans. Osteoporos Int (2007) 0.92
Rationale and design of the Post-MI FREEE trial: a randomized evaluation of first-dollar drug coverage for post-myocardial infarction secondary preventive therapies. Am Heart J (2008) 0.92
A "hot" topic in dyslipidemia management--"how to beat a flush": optimizing niacin tolerability to promote long-term treatment adherence and coronary disease prevention. Mayo Clin Proc (2010) 0.91
A cross-national study of the persistence of antihypertensive medication use in the elderly. J Hypertens (2008) 0.91
Adherence with statins in a real-life setting is better when associated cardiovascular risk factors increase: a cohort study. BMC Cardiovasc Disord (2011) 0.91
Risk of pneumonia in patients taking statins: population-based nested case-control study. Br J Gen Pract (2011) 0.90
Barriers to detecting and treating hypercholesterolaemia in patients with ischaemic heart disease: primary care perceptions. Br J Gen Pract (2005) 0.90
Tailored Information and Automated Reminding to Improve Medication Adherence in Spanish- and English-Speaking Elders Treated for Memory Impairment. Clin Gerontol (2012) 0.90
n-3 Polyunsaturated fatty acids supplementation in peripheral artery disease: the OMEGA-PAD trial. Vasc Med (2013) 0.89
Adherence to lipid-lowering treatment: the patient perspective. Patient Prefer Adherence (2012) 0.89
Initiation and persistence to statin treatment in patients with diabetes receiving glucose-lowering medications 1997- 2006. Open Cardiovasc Med J (2009) 0.89
Cardiac medication prescribing and adherence after acute myocardial infarction in Chinese and South Asian Canadian patients. BMC Cardiovasc Disord (2011) 0.88
Outcomes after switching from one bisphosphonate to another in 146 patients at a single university hospital. Osteoporos Int (2008) 0.88
Racial differences in antilipemic use and lipid control in high-risk older adults: post-Medicare Part D. Am Heart J (2013) 0.87
The combination of pill count and self-reported adherence is a strong predictor of first-line ART failure for adults in South Africa. Curr HIV Res (2014) 0.87
Discontinuation and switching of therapy after initiation of lipid-lowering drugs: the effects of comorbidities and patient characteristics. Br J Clin Pharmacol (2003) 0.87
A nested case-control study of adjuvant hormonal therapy persistence and compliance, and early breast cancer recurrence in women with stage I-III breast cancer. Br J Cancer (2013) 0.87
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med (2008) 43.36
Variable selection for propensity score models. Am J Epidemiol (2006) 10.68
Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet (2009) 10.52
A review of uses of health care utilization databases for epidemiologic research on therapeutics. J Clin Epidemiol (2005) 8.77
Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism. N Engl J Med (2003) 8.65
Expanded screening for HIV in the United States--an analysis of cost-effectiveness. N Engl J Med (2005) 8.49
Risk of death in elderly users of conventional vs. atypical antipsychotic medications. N Engl J Med (2005) 8.44
Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 8.32
High-dimensional propensity score adjustment in studies of treatment effects using health care claims data. Epidemiology (2009) 7.40
A review of the application of propensity score methods yielded increasing use, advantages in specific settings, but not substantially different estimates compared with conventional multivariable methods. J Clin Epidemiol (2005) 7.31
The survival benefits of AIDS treatment in the United States. J Infect Dis (2006) 7.08
Accuracy of Medicare claims-based diagnosis of acute myocardial infarction: estimating positive predictive value on the basis of review of hospital records. Am Heart J (2004) 6.57
Results of multivariable logistic regression, propensity matching, propensity adjustment, and propensity-based weighting under conditions of nonuniform effect. Am J Epidemiol (2005) 6.20
The lifetime cost of current human immunodeficiency virus care in the United States. Med Care (2006) 5.87
Cost-effectiveness of HIV treatment in resource-poor settings--the case of Côte d'Ivoire. N Engl J Med (2006) 5.62
Expanded HIV screening in the United States: effect on clinical outcomes, HIV transmission, and costs. Ann Intern Med (2006) 5.53
A randomized study of how physicians interpret research funding disclosures. N Engl J Med (2012) 5.47
Multivitamins in the prevention of cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 5.25
Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 5.13
Antidepressant use in pregnancy and the risk of cardiac defects. N Engl J Med (2014) 4.99
Nonadherence to adjuvant tamoxifen therapy in women with primary breast cancer. J Clin Oncol (2003) 4.95
Does preventive care save money? Health economics and the presidential candidates. N Engl J Med (2008) 4.78
Risk of death and cardiovascular events in initially healthy women with new-onset atrial fibrillation. JAMA (2011) 4.73
Self-management education programs in chronic disease: a systematic review and methodological critique of the literature. Arch Intern Med (2004) 4.68
Full coverage for preventive medications after myocardial infarction. N Engl J Med (2011) 4.51
The comparative safety of analgesics in older adults with arthritis. Arch Intern Med (2010) 4.47
Cardiovascular benefits and diabetes risks of statin therapy in primary prevention: an analysis from the JUPITER trial. Lancet (2012) 4.46
Economic savings versus health losses: the cost-effectiveness of generic antiretroviral therapy in the United States. Ann Intern Med (2013) 4.43
Multivitamins in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 4.40
When to start antiretroviral therapy in resource-limited settings. Ann Intern Med (2009) 4.31
New FDA breakthrough-drug category--implications for patients. N Engl J Med (2014) 4.30
Medicare and cost-effectiveness analysis. N Engl J Med (2005) 4.20
Adherence to therapy with oral antineoplastic agents. J Natl Cancer Inst (2002) 4.16
HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial. Lancet (2010) 4.07
Outcomes of reference pricing for angiotensin-converting-enzyme inhibitors. N Engl J Med (2002) 4.07
Depression and risk of sudden cardiac death and coronary heart disease in women: results from the Nurses' Health Study. J Am Coll Cardiol (2009) 3.99
A combined comorbidity score predicted mortality in elderly patients better than existing scores. J Clin Epidemiol (2011) 3.98
Use of antidepressants near delivery and risk of postpartum hemorrhage: cohort study of low income women in the United States. BMJ (2013) 3.88
Anticonvulsant medications and the risk of suicide, attempted suicide, or violent death. JAMA (2010) 3.85
Adherence to lipid-lowering therapy and the use of preventive health services: an investigation of the healthy user effect. Am J Epidemiol (2007) 3.82
The epidemiology of prescriptions abandoned at the pharmacy. Ann Intern Med (2010) 3.78
The implications of choice: prescribing generic or preferred pharmaceuticals improves medication adherence for chronic conditions. Arch Intern Med (2006) 3.64
Burden of changes in pill appearance for patients receiving generic cardiovascular medications after myocardial infarction: cohort and nested case-control studies. Ann Intern Med (2014) 3.62
Cardiovascular disease prevention with a multidrug regimen in the developing world: a cost-effectiveness analysis. Lancet (2006) 3.60
Updating cost-effectiveness--the curious resilience of the $50,000-per-QALY threshold. N Engl J Med (2014) 3.57
Effect of smoking on comparative efficacy of antiplatelet agents: systematic review, meta-analysis, and indirect comparison. BMJ (2013) 3.43
Examining the value and quality of health economic analyses: implications of utilizing the QHES. J Manag Care Pharm (2003) 3.34
The quality of pharmacologic care for vulnerable older patients. Ann Intern Med (2004) 3.34
Analytic strategies to adjust confounding using exposure propensity scores and disease risk scores: nonsteroidal antiinflammatory drugs and short-term mortality in the elderly. Am J Epidemiol (2005) 3.33
Racial and sex disparities in life expectancy losses among HIV-infected persons in the united states: impact of risk behavior, late initiation, and early discontinuation of antiretroviral therapy. Clin Infect Dis (2009) 3.30
The implications of therapeutic complexity on adherence to cardiovascular medications. Arch Intern Med (2011) 3.27
Cost-effectiveness of treatment for chronic hepatitis C infection in an evolving patient population. JAMA (2003) 3.25
Rethinking the use of physicians as hired expert lecturers. Ann Intern Med (2014) 3.22
Blood pressure and risk of developing type 2 diabetes mellitus: the Women's Health Study. Eur Heart J (2007) 3.21
Drug-review deadlines and safety problems. N Engl J Med (2008) 3.16
Variations in pill appearance of antiepileptic drugs and the risk of nonadherence. JAMA Intern Med (2013) 3.13
Projected clinical benefits and cost-effectiveness of a human papillomavirus 16/18 vaccine. J Natl Cancer Inst (2004) 3.11
Cost-effectiveness of HIV treatment as prevention in serodiscordant couples. N Engl J Med (2013) 3.10
Impact of referral patterns on the use of chemotherapy for lung cancer. J Clin Oncol (2002) 3.09
Cardiovascular outcomes and mortality in patients using clopidogrel with proton pump inhibitors after percutaneous coronary intervention or acute coronary syndrome. Circulation (2009) 3.09
Balancing innovation, access, and profits--market exclusivity for biologics. N Engl J Med (2009) 3.08
Using real-world data for coverage and payment decisions: the ISPOR Real-World Data Task Force report. Value Health (2007) 3.05
Tumor necrosis factor alpha antagonist use and cancer in patients with rheumatoid arthritis. Arthritis Rheum (2006) 3.04
High-density lipoprotein cholesterol, size, particle number, and residual vascular risk after potent statin therapy. Circulation (2013) 3.03
Confounding control in healthcare database research: challenges and potential approaches. Med Care (2010) 3.01
Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults. Circulation (2004) 2.98
Scaling up antiretroviral therapy in South Africa: the impact of speed on survival. J Infect Dis (2008) 2.96
University-based science and biotechnology products: defining the boundaries of intellectual property. JAMA (2005) 2.95
Compliance with osteoporosis medications. Arch Intern Med (2005) 2.91
Noncompliance with antihypertensive medications: the impact of depressive symptoms and psychosocial factors. J Gen Intern Med (2002) 2.85
Cost-effectiveness of computed tomography screening for lung cancer in the United States. J Thorac Oncol (2011) 2.83
Nonsteroidal anti-inflammatory drug use and acute myocardial infarction. Arch Intern Med (2002) 2.82
Selective prescribing led to overestimation of the benefits of lipid-lowering drugs. J Clin Epidemiol (2006) 2.81
HER-2 testing and trastuzumab therapy for metastatic breast cancer: a cost-effectiveness analysis. J Clin Oncol (2004) 2.78
Internet marketing of herbal products. JAMA (2003) 2.77
Economic implications of evidence-based prescribing for hypertension: can better care cost less? JAMA (2004) 2.77
Treatment effects in the presence of unmeasured confounding: dealing with observations in the tails of the propensity score distribution--a simulation study. Am J Epidemiol (2010) 2.74