Published in JAMA on November 09, 2008
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Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2011) 11.02
Dietary supplements and mortality rate in older women: the Iowa Women's Health Study. Arch Intern Med (2011) 6.69
Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med (2009) 6.16
Multivitamins in the prevention of cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 5.25
Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 5.13
Multivitamins in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 4.40
Therapeutic targeting of mitochondrial superoxide in hypertension. Circ Res (2010) 3.16
Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer. J Natl Cancer Inst (2009) 2.53
Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalent. Arch Intern Med (2011) 2.43
Long-term multivitamin supplementation and cognitive function in men: a randomized trial. Ann Intern Med (2013) 2.39
Antioxidants in Translational Medicine. Antioxid Redox Signal (2015) 2.32
Reactive oxygen species in cardiovascular disease. Free Radic Biol Med (2011) 2.29
A randomized trial of beta carotene supplementation and cognitive function in men: the Physicians' Health Study II. Arch Intern Med (2007) 2.20
Vitamins C and E: beneficial effects from a mechanistic perspective. Free Radic Biol Med (2011) 1.93
Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials. Am J Clin Nutr (2012) 1.79
Novel Biomarker of Oxidative Stress Is Associated With Risk of Death in Patients With Coronary Artery Disease. Circulation (2015) 1.69
Calorie restriction and prevention of age-associated chronic disease. FEBS Lett (2011) 1.69
Physiological levels of reactive oxygen species are required to maintain genomic stability in stem cells. Stem Cells (2010) 1.63
Age-related cataract in a randomized trial of vitamins E and C in men. Arch Ophthalmol (2010) 1.60
Greater variety in fruit and vegetable intake is associated with lower inflammation in Puerto Rican adults. Am J Clin Nutr (2010) 1.56
Effect of oral vitamin C supplementation on serum uric acid: a meta-analysis of randomized controlled trials. Arthritis Care Res (Hoboken) (2011) 1.56
Nutrition and physical activity in NAFLD: an overview of the epidemiological evidence. World J Gastroenterol (2011) 1.48
Fruits, vegetables and coronary heart disease. Nat Rev Cardiol (2009) 1.47
Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries. Adv Nutr (2011) 1.45
Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials. BMJ (2010) 1.43
Trends in Dietary Supplement Use Among US Adults From 1999-2012. JAMA (2016) 1.42
Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype. Pharmacogenomics (2010) 1.42
Use of supplements of multivitamins, vitamin C, and vitamin E in relation to mortality. Am J Epidemiol (2009) 1.42
Cysteine/cystine redox signaling in cardiovascular disease. Free Radic Biol Med (2010) 1.42
Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers. J Hematol Oncol (2013) 1.42
Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in Hypertension. Circ Res (2015) 1.40
Self-medication among children and adolescents in Germany: results of the National Health Survey for Children and Adolescents (KiGGS). Br J Clin Pharmacol (2009) 1.32
Oxidative Stress and Inflammation in Heart Disease: Do Antioxidants Have a Role in Treatment and/or Prevention? Int J Inflam (2011) 1.30
Nox5 and the regulation of cellular function. Antioxid Redox Signal (2009) 1.28
NADPH oxidases in heart failure: poachers or gamekeepers? Antioxid Redox Signal (2012) 1.27
Raw and processed fruit and vegetable consumption and 10-year coronary heart disease incidence in a population-based cohort study in the Netherlands. PLoS One (2010) 1.24
p53, oxidative stress, and aging. Antioxid Redox Signal (2011) 1.18
Redox signaling in cardiovascular health and disease. Free Radic Biol Med (2013) 1.16
Obesity-associated oxidative stress: strategies finalized to improve redox state. Int J Mol Sci (2013) 1.15
The role of oxidized low-density lipoproteins in atherosclerosis: the myths and the facts. Mediators Inflamm (2013) 1.15
Mediterranean diet and cognitive decline in women with cardiovascular disease or risk factors. J Acad Nutr Diet (2012) 1.15
Reactive oxygen species, vascular Noxs, and hypertension: focus on translational and clinical research. Antioxid Redox Signal (2013) 1.14
Vitamin and mineral supplements: do we really need them? Int J Prev Med (2012) 1.14
Mitochondrial longevity pathways. Biochim Biophys Acta (2011) 1.11
Effects of aging on angiogenesis. Circ Res (2012) 1.10
Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death. Circ Arrhythm Electrophysiol (2013) 1.10
OLA1, an Obg-like ATPase, suppresses antioxidant response via nontranscriptional mechanisms. Proc Natl Acad Sci U S A (2009) 1.09
The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes. Atherosclerosis (2010) 1.08
The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes. Diabetologia (2010) 1.06
Chronic kidney disease and the risk of heart failure in men. Circ Heart Fail (2011) 1.05
Regulation of cell physiology and pathology by protein S-glutathionylation: lessons learned from the cardiovascular system. Antioxid Redox Signal (2012) 1.03
A flood of health functional foods: what is to be recommended? J Menopausal Med (2015) 1.03
The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication. Am J Transl Res (2010) 1.03
Plasma and dietary antioxidant status as cardiovascular disease risk factors: a review of human studies. Nutrients (2013) 1.02
Vitamin E and all-cause mortality: a meta-analysis. Curr Aging Sci (2011) 1.01
Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS). Dose Response (2014) 1.00
Effect of citrus flavonoids, naringin and naringenin, on metabolic syndrome and their mechanisms of action. Adv Nutr (2014) 0.99
Vitamin E in the prevention of cardiovascular disease: the importance of proper patient selection. J Lipid Res (2013) 0.99
Oral tocotrienols are transported to human tissues and delay the progression of the model for end-stage liver disease score in patients. J Nutr (2012) 0.99
Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself. Am J Clin Nutr (2012) 0.98
Natural antioxidants and hypertension: promise and challenges. Cardiovasc Ther (2010) 0.98
Perspectives of Targeting mTORC1-S6K1 in Cardiovascular Aging. Front Physiol (2012) 0.97
Role of vitamin C in the function of the vascular endothelium. Antioxid Redox Signal (2013) 0.97
Effect of antioxidant vitamin supplementation on cardiovascular outcomes: a meta-analysis of randomized controlled trials. PLoS One (2013) 0.96
Plasma and dietary omega-3 fatty acids, fish intake, and heart failure risk in the Physicians' Health Study. Am J Clin Nutr (2012) 0.93
Isoforms of vitamin E differentially regulate inflammation. Endocr Metab Immune Disord Drug Targets (2010) 0.93
Prostate-specific membrane antigen protein expression in tumor tissue and risk of lethal prostate cancer. Cancer Epidemiol Biomarkers Prev (2013) 0.93
The 2015 Dutch food-based dietary guidelines. Eur J Clin Nutr (2016) 0.92
Dietary habits and behaviors associated with nonalcoholic fatty liver disease. World J Gastroenterol (2014) 0.91
Effects of multivitamin supplement on cataract and age-related macular degeneration in a randomized trial of male physicians. Ophthalmology (2013) 0.91
Atherosclerosis in chronic kidney disease: the role of macrophages. Nat Rev Nephrol (2010) 0.91
Red blood cell membrane concentration of cis-palmitoleic and cis-vaccenic acids and risk of coronary heart disease. Am J Cardiol (2012) 0.90
Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications. Antioxid Redox Signal (2015) 0.89
Alcohol consumption and functional outcome after stroke in men. Stroke (2009) 0.89
Modification of the effect of vitamin E supplementation on the mortality of male smokers by age and dietary vitamin C. Am J Epidemiol (2009) 0.89
Chemoprevention of prostate cancer: an updated view. World J Urol (2012) 0.89
A study of pyrimidine base damage in relation to oxidative stress and cancer. Br J Cancer (2009) 0.88
Empirically-derived dietary patterns, diet quality scores, and markers of inflammation and endothelial dysfunction. Curr Nutr Rep (2013) 0.88
Reactive oxygen species-targeted therapeutic interventions for atrial fibrillation. Front Physiol (2012) 0.88
Isoforms of Vitamin E Differentially Regulate PKC α and Inflammation: A Review. J Clin Cell Immunol (2013) 0.87
Alpha-tocopherol is ineffective in preventing the decomposition of preformed lipid peroxides and may promote the accumulation of toxic aldehydes: a potential explanation for the failure of antioxidants to affect human atherosclerosis. Antioxid Redox Signal (2009) 0.87
Antioxidant vitamins and their use in preventing cardiovascular disease. Molecules (2010) 0.87
Clinical and experimental evidence for oxidative stress as an exacerbating factor of diabetes mellitus. J Clin Biochem Nutr (2010) 0.87
Pathogenesis of target organ damage in hypertension: role of mitochondrial oxidative stress. Int J Mol Sci (2014) 0.87
Engineering biodegradable polyester elastomers with antioxidant properties to attenuate oxidative stress in tissues. Biomaterials (2014) 0.87
Antioxidant Supplementation in the Treatment of Aging-Associated Diseases. Front Pharmacol (2016) 0.86
SIRT1, p66(Shc), and Set7/9 in vascular hyperglycemic memory: bringing all the strands together. Diabetes (2013) 0.86
Current treatment options for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Can J Gastroenterol (2012) 0.86
Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox? Oxid Med Cell Longev (2016) 0.86
Cellular and Molecular Mechanisms of Arrhythmia by Oxidative Stress. Cardiol Res Pract (2016) 0.85
Vitamin C intake, circulating vitamin C and risk of stroke: a meta-analysis of prospective studies. J Am Heart Assoc (2013) 0.85
Functional foods and nutraceuticals in the primary prevention of cardiovascular diseases. J Nutr Metab (2012) 0.84
Supplementation with tocotrienol-rich fraction alters the plasma levels of Apolipoprotein A-I precursor, Apolipoprotein E precursor, and C-reactive protein precursor from young and old individuals. Eur J Nutr (2013) 0.84
Dietary antioxidant capacity is associated with improved serum antioxidant status and decreased serum C-reactive protein and plasma homocysteine concentrations. Eur J Nutr (2013) 0.84
Oxidative Stress and the Use of Antioxidants in Stroke. Antioxidants (Basel) (2014) 0.84
Antioxidant therapy in nonalcoholic steatohepatitis. Hepat Res Treat (2012) 0.83
Regulatory metabolites of vitamin E and their putative relevance for atherogenesis. Redox Biol (2014) 0.83
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Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Multivitamins and Probucol Study Group. N Engl J Med (1997) 4.51
The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals. Arch Intern Med (2004) 4.47
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Dietary antioxidant vitamins and death from coronary heart disease in postmenopausal women. N Engl J Med (1996) 3.34
Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT). J Natl Cancer Inst (2005) 2.99
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Dietary supplement use and mortality in a cohort of Swedish men. Br J Nutr (2007) 1.73
Vitamin C deficiency and depletion in the United States: the Third National Health and Nutrition Examination Survey, 1988 to 1994. Am J Public Health (2004) 1.73
New developments and novel therapeutic perspectives for vitamin C. J Nutr (2007) 1.57
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Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. Am J Clin Nutr (2004) 1.35
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Dietary antioxidants and risk of myocardial infarction in the elderly: the Rotterdam Study. Am J Clin Nutr (1999) 1.04
Vitamins C and E prolong time to arterial thrombosis in rats. J Nutr (1999) 1.01
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Possible prevention of postangioplasty restenosis by ascorbic acid. Am J Cardiol (1996) 0.91
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med (2008) 43.36
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Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med (2002) 16.23
Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score. JAMA (2007) 15.32
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2008) 13.35
The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab (2010) 13.29
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 12.44
Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med (2006) 12.09
Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. JAMA (2005) 12.09
Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA (2004) 11.69
Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2011) 11.02
Variable selection for propensity score models. Am J Epidemiol (2006) 10.68
Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet (2009) 10.52
Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA (2007) 10.50
Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA (2003) 10.05
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA (2007) 9.68
A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med (2003) 9.24
Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial. JAMA (2005) 9.03
Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med (2006) 8.73
Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism. N Engl J Med (2003) 8.65
Adiposity as compared with physical activity in predicting mortality among women. N Engl J Med (2004) 8.63
High-dimensional propensity score adjustment in studies of treatment effects using health care claims data. Epidemiology (2009) 7.40
A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care (2003) 7.40
C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men. Circulation (2008) 7.33
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A review of the application of propensity score methods yielded increasing use, advantages in specific settings, but not substantially different estimates compared with conventional multivariable methods. J Clin Epidemiol (2005) 7.31
Long-term persistence in use of statin therapy in elderly patients. JAMA (2002) 7.19
Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA (2010) 7.12
C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women. Circulation (2003) 6.99
Calcium/vitamin D supplementation and cardiovascular events. Circulation (2007) 6.63
Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation (2003) 6.62
Accuracy of Medicare claims-based diagnosis of acute myocardial infarction: estimating positive predictive value on the basis of review of hospital records. Am Heart J (2004) 6.57
Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 6.51
Body-mass index and mortality among adults with incident type 2 diabetes. N Engl J Med (2014) 6.51
Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals. Arch Intern Med (2010) 6.48
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation (2007) 6.34
Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Arch Intern Med (2007) 6.29
Results of multivariable logistic regression, propensity matching, propensity adjustment, and propensity-based weighting under conditions of nonuniform effect. Am J Epidemiol (2005) 6.20
Migraine and risk of cardiovascular disease in women. JAMA (2006) 6.16
Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med (2009) 6.16
Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3. Ann Intern Med (2009) 6.00
Hemoglobin A1c predicts diabetes but not cardiovascular disease in nondiabetic women. Am J Med (2007) 5.95
Inflammatory markers and the risk of coronary heart disease in men and women. N Engl J Med (2004) 5.86
C-reactive protein and the risk of developing hypertension. JAMA (2003) 5.75
Low-fat dietary pattern and weight change over 7 years: the Women's Health Initiative Dietary Modification Trial. JAMA (2006) 5.75
Non-HDL cholesterol, apolipoproteins A-I and B100, standard lipid measures, lipid ratios, and CRP as risk factors for cardiovascular disease in women. JAMA (2005) 5.74
The effect of including C-reactive protein in cardiovascular risk prediction models for women. Ann Intern Med (2006) 5.69
Coffee consumption and risk for type 2 diabetes mellitus. Ann Intern Med (2004) 5.67
Laboratory-based versus non-laboratory-based method for assessment of cardiovascular disease risk: the NHANES I Follow-up Study cohort. Lancet (2008) 5.49
A randomized study of how physicians interpret research funding disclosures. N Engl J Med (2012) 5.47
Measures of obesity and cardiovascular risk among men and women. J Am Coll Cardiol (2008) 5.28
Physical activity and weight gain prevention. JAMA (2010) 5.27
Multivitamins in the prevention of cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 5.25
Oestrogen plus progestin and lung cancer in postmenopausal women (Women's Health Initiative trial): a post-hoc analysis of a randomised controlled trial. Lancet (2009) 5.22
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14
Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 5.13
Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular events. Ann Intern Med (2010) 5.05
Migraine and cardiovascular disease: systematic review and meta-analysis. BMJ (2009) 4.98
Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med (2014) 4.94
Physical activity, including walking, and cognitive function in older women. JAMA (2004) 4.90
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Effects of estrogen plus progestin on health-related quality of life. N Engl J Med (2003) 4.83
Breast cancer after use of estrogen plus progestin in postmenopausal women. N Engl J Med (2009) 4.80
Risk of death and cardiovascular events in initially healthy women with new-onset atrial fibrillation. JAMA (2011) 4.73
Red meat consumption and mortality: results from 2 prospective cohort studies. Arch Intern Med (2012) 4.72