Published in Nucleic Acids Res on July 15, 2002
Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference. Nucleic Acids Res (2004) 1.99
Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoform. Mol Cell Biol (2003) 1.79
Destabilization of interleukin-6 mRNA requires a putative RNA stem-loop structure, an AU-rich element, and the RNA-binding protein AUF1. Mol Cell Biol (2006) 1.77
The role of AUF1 in regulated mRNA decay. Wiley Interdiscip Rev RNA (2011) 1.34
Tumor necrosis factor activates a conserved innate antiviral response to hepatitis B virus that destabilizes nucleocapsids and reduces nuclear viral DNA. J Virol (2007) 1.27
Assembly of AUF1 with eIF4G-poly(A) binding protein complex suggests a translation function in AU-rich mRNA decay. RNA (2006) 1.22
Post-transcriptional control of gene expression by AUF1: mechanisms, physiological targets, and regulation. Biochim Biophys Acta (2012) 1.16
FRET-detectable interactions between the ARE binding proteins, HuR and p37AUF1. RNA (2007) 1.08
Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1. Front Biosci (Landmark Ed) (2011) 1.06
Chaperone Hsp27 modulates AUF1 proteolysis and AU-rich element-mediated mRNA degradation. Mol Cell Biol (2011) 1.01
Association of the von Hippel-Lindau protein with AUF1 and posttranscriptional regulation of VEGFA mRNA. Mol Cancer Res (2011) 0.97
Members of the NuRD chromatin remodeling complex interact with AUF1 in developing cortical neurons. Cereb Cortex (2008) 0.95
Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region. Mol Cancer Ther (2008) 0.93
AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 mRNA stability. Mol Cell Biol (2006) 0.90
Differential effects of hnRNP D/AUF1 isoforms on HIV-1 gene expression. Nucleic Acids Res (2011) 0.90
The Regulation of Synaptic Protein Turnover. J Biol Chem (2015) 0.87
Suppression of HPV-16 late L1 5'-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs. Nucleic Acids Res (2013) 0.83
Concurrent binding and modifications of AUF1 and HuR mediate the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in kidney cells. Am J Physiol Renal Physiol (2012) 0.83
AUF-1 and YB-1 are critical determinants of β-globin mRNA expression in erythroid cells. Blood (2011) 0.80
Impairment of FOS mRNA stabilization following translation arrest in granulocytes from myelodysplastic syndrome patients. PLoS One (2013) 0.76
Reduction of c-Fos via Overexpression of miR-34a Results in Enhancement of TNF- Production by LPS in Neutrophils from Myelodysplastic Syndrome Patients. PLoS One (2016) 0.75
AU-rich elements: characterization and importance in mRNA degradation. Trends Biochem Sci (1995) 14.81
Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain. Cell (1994) 8.65
HuR and mRNA stability. Cell Mol Life Sci (2001) 8.06
AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell (2001) 7.79
Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J (1998) 7.62
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown. J Biol Chem (1983) 7.03
RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein. EMBO J (1998) 6.68
The cap-to-tail guide to mRNA turnover. Nat Rev Mol Cell Biol (2001) 6.67
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol Cell Biol (1999) 5.55
Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1. Mol Cell Biol (1993) 5.24
Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev (1997) 5.22
Regulation of mRNA stability in mammalian cells. Gene (2001) 4.55
An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro. Mol Cell Biol (1991) 4.31
HuR binding to cytoplasmic mRNA is perturbed by heat shock. Proc Natl Acad Sci U S A (2000) 4.14
Control of mRNA decay by heat shock-ubiquitin-proteasome pathway. Science (1999) 4.10
Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay. EMBO J (1997) 3.91
Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability. Blood (2000) 3.86
Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element. Genes Dev (1999) 3.59
ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system. Genes Dev (1999) 3.45
The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene. Nature (1993) 3.33
mRNA stability in eukaryotes. Curr Opin Genet Dev (2000) 3.01
Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome. Semin Cell Dev Biol (2000) 2.85
Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Mol Cell Biol (1993) 2.84
AUF1 binding affinity to A+U-rich elements correlates with rapid mRNA degradation. J Biol Chem (1996) 2.67
Ubiquitin-activating enzyme. Mechanism and role in protein-ubiquitin conjugation. J Biol Chem (1982) 2.65
Functional heterogeneity of ubiquitin carrier proteins. J Biol Chem (1985) 2.53
Structure and genomic organization of the human AUF1 gene: alternative pre-mRNA splicing generates four protein isoforms. Genomics (1998) 2.17
Inhibition of the 26 S proteasome by polyubiquitin chains synthesized to have defined lengths. J Biol Chem (1997) 2.14
Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway. Mol Cell Biol (2000) 2.12
The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR. Mol Cell Biol (2001) 2.09
In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome. EMBO J (1997) 2.03
The search for trans-acting factors controlling messenger RNA decay. Prog Nucleic Acid Res Mol Biol (1999) 1.93
Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnover. Mol Cell Biol (2001) 1.92
Identification of AUF1 (heterogeneous nuclear ribonucleoprotein D) as a component of the alpha-globin mRNA stability complex. Mol Cell Biol (1997) 1.83
Adenovirus inhibition of cellular protein synthesis involves inactivation of cap-binding protein. Cell (1991) 1.82
UBPY: a growth-regulated human ubiquitin isopeptidase. EMBO J (1998) 1.76
Adhesion-dependent regulation of an A+U-rich element-binding activity associated with AUF1. Mol Cell Biol (1997) 1.59
Nucleolin is one component of the B cell-specific transcription factor and switch region binding protein, LR1. Proc Natl Acad Sci U S A (1997) 1.52
The UUAG-specific RNA binding protein, heterogeneous nuclear ribonucleoprotein D0. Common modular structure and binding properties of the 2xRBD-Gly family. J Biol Chem (1995) 1.50
SUMO-1 conjugation to human DNA topoisomerase II isozymes. J Biol Chem (2000) 1.48
A ubiquitin C-terminal isopeptidase that acts on polyubiquitin chains. Role in protein degradation. J Biol Chem (1992) 1.48
Degradation of the proto-oncogene product c-Fos by the ubiquitin proteolytic system in vivo and in vitro: identification and characterization of the conjugating enzymes. Mol Cell Biol (1995) 1.48
Ubiquitin-dependent mechanism regulates rapid turnover of AU-rich cytokine mRNAs. Proc Natl Acad Sci U S A (2002) 1.46
Regulation of the mRNA-binding protein AUF1 by activation of the beta-adrenergic receptor signal transduction pathway. J Biol Chem (1996) 1.42
In vitro properties of the conserved mammalian protein hnRNP D suggest a role in telomere maintenance. Mol Cell Biol (2000) 1.34
A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: canonical RNA binding motifs in a sequence-specific duplex DNA binding protein. J Biol Chem (1998) 1.31
The ubiquitin-mediated proteolytic pathway as a therapeutic area. J Mol Med (Berl) (1997) 1.29
Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation. Mol Cell Biol (1996) 1.24
Regulation of the Epstein-Barr virus C promoter by AUF1 and the cyclic AMP/protein kinase A signaling pathway. J Virol (2000) 1.23
Kinetic studies of isopeptidase T: modulation of peptidase activity by ubiquitin. Biochemistry (1995) 1.07
The human HNRPD locus maps to 4q21 and encodes a highly conserved protein. Genomics (1998) 1.06
The Unp proto-oncogene encodes a nuclear protein. Oncogene (1994) 1.05
Relationships between proteasomes and RNA. Mol Biol Rep (1995) 1.05
Unp, a mouse gene related to the tre oncogene. Oncogene (1993) 1.02
LR1 regulates c-myc transcription in B-cell lymphomas. Proc Natl Acad Sci U S A (1994) 1.02
Elevated expression of Unph, a proto-oncogene at 3p21.3, in human lung tumors. Oncogene (1995) 1.01
Polyamine analogues inhibit the ubiquitination of spermidine/spermine N1-acetyltransferase and prevent its targeting to the proteasome for degradation. Biochem J (2001) 0.99
Protein degradation: de-ubiquitinate to decide your fate. Curr Biol (1996) 0.92
Identification and initial characterization of a specific proteasome (prosome) associated RNase activity. J Biol Chem (1995) 0.83
Translational control in cancer. Nat Rev Cancer (2010) 4.59
The enigmatic X gene of hepatitis B virus. J Virol (2004) 2.98
Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells. J Immunol (2008) 2.61
Radiotherapy treatment of early-stage prostate cancer with IMRT and protons: a treatment planning comparison. Int J Radiat Oncol Biol Phys (2007) 2.55
A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer. Mol Cell (2007) 2.44
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. J Cell Biol (2008) 2.26
Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer. Nat Cell Biol (2009) 1.99
Transforming growth factor-beta and microRNA:mRNA regulatory networks in epithelial plasticity. Cells Tissues Organs (2007) 1.95
mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription. Mol Cell (2012) 1.86
Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoform. Mol Cell Biol (2003) 1.79
Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells. Mol Cell Biol (2006) 1.76
Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs. Genes Dev (2006) 1.74
Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay. J Biol Chem (2004) 1.63
Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR. J Biol Chem (2002) 1.61
Ethical, legal, and social issues related to genomics and cancer research: the impending crisis. J Am Coll Radiol (2005) 1.60
Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid Integrity through activation of NF-kappaB. J Virol (2003) 1.55
Nuclear import and export functions in the different isoforms of the AUF1/heterogeneous nuclear ribonucleoprotein protein family. J Biol Chem (2003) 1.54
Regulation of protein synthesis by ionizing radiation. Mol Cell Biol (2009) 1.52
Hepatitis B virus DNA replication is coordinated by core protein serine phosphorylation and HBx expression. J Virol (2005) 1.47
Ubiquitin-dependent mechanism regulates rapid turnover of AU-rich cytokine mRNAs. Proc Natl Acad Sci U S A (2002) 1.46
Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation. Clin Cancer Res (2010) 1.43
Tethering of eIF4G to adenoviral mRNAs by viral 100k protein drives ribosome shunting. Genes Dev (2004) 1.30
Activation and inhibition of cellular calcium and tyrosine kinase signaling pathways identify targets of the HBx protein involved in hepatitis B virus replication. J Virol (2003) 1.28
Tumor necrosis factor activates a conserved innate antiviral response to hepatitis B virus that destabilizes nucleocapsids and reduces nuclear viral DNA. J Virol (2007) 1.27
Assembly of AUF1 with eIF4G-poly(A) binding protein complex suggests a translation function in AU-rich mRNA decay. RNA (2006) 1.22
Preoperative concurrent paclitaxel-radiation in locally advanced breast cancer: pathologic response correlates with five-year overall survival. Breast Cancer Res Treat (2010) 1.12
Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease. J Invest Dermatol (2008) 1.10
Mitotic raptor promotes mTORC1 activity, G(2)/M cell cycle progression, and internal ribosome entry site-mediated mRNA translation. Mol Cell Biol (2010) 1.09
Intra- and interfractional patient motion for a variety of immobilization devices. Med Phys (2005) 1.09
Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kilodalton protein. J Virol (2004) 1.03
Low-dose radiation augments vasculogenesis signaling through HIF-1-dependent and -independent SDF-1 induction. Blood (2010) 1.03
Lsm proteins bind and stabilize RNAs containing 5' poly(A) tracts. Nat Struct Mol Biol (2007) 1.02
The cochaperone p23 differentially regulates estrogen receptor target genes and promotes tumor cell adhesion and invasion. Mol Cell Biol (2006) 1.02
Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication. J Virol (2006) 1.01
DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs. Proc Natl Acad Sci U S A (2012) 1.00
Regulation of translation by ribosome shunting through phosphotyrosine-dependent coupling of adenovirus protein 100k to viral mRNAs. J Virol (2005) 0.99
Inflammatory breast cancer cells are constitutively adapted to hypoxia. Cell Cycle (2009) 0.98
UV-induction of keratinocyte endothelin-1 downregulates E-cadherin in melanocytes and melanoma cells. J Clin Invest (2002) 0.98
Human cytomegalovirus infection enhances NF-κB/p65 signaling in inflammatory breast cancer patients. PLoS One (2013) 0.98
High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance. Cancer Res (2010) 0.97
Members of the NuRD chromatin remodeling complex interact with AUF1 in developing cortical neurons. Cereb Cortex (2008) 0.95
AUF1 is involved in splenic follicular B cell maintenance. BMC Immunol (2010) 0.94
Acquisition of stable inducible up-regulation of nuclear factor-kappaB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells. Mol Cancer Res (2008) 0.92
Similar regulation of human inducible nitric-oxide synthase expression by different isoforms of the RNA-binding protein AUF1. J Biol Chem (2008) 0.91
Targeting the mTOR/4E-BP pathway in endometrial cancer. Clin Cancer Res (2011) 0.90
Androgen receptor coactivator p44/Mep50 in breast cancer growth and invasion. J Cell Mol Med (2010) 0.90
Atypical ezrin localization as a marker of locally advanced breast cancer. Breast Cancer Res Treat (2012) 0.89
Cutaneous low-dose radiation increases tissue vascularity through upregulation of angiogenic and vasculogenic pathways. J Vasc Res (2010) 0.88
The role of health system factors in delaying final diagnosis and treatment of breast cancer in Mexico City, Mexico. Breast (2011) 0.87
Dyskerin depletion increases VEGF mRNA internal ribosome entry site-mediated translation. Nucleic Acids Res (2013) 0.87
Childhood abuse and intake severity in alcohol disorder patients. J Trauma Stress (2006) 0.86
Anti-tumor effects of Ganoderma lucidum (reishi) in inflammatory breast cancer in in vivo and in vitro models. PLoS One (2013) 0.86
Interstitial fluid pressure correlates with intravoxel incoherent motion imaging metrics in a mouse mammary carcinoma model. NMR Biomed (2011) 0.86
Vitronectin-αvβ3 integrin engagement directs hypoxia-resistant mTOR activity and sustained protein synthesis linked to invasion by breast cancer cells. Cancer Res (2013) 0.85
Alcohol relapses associated with September 11, 2001: a case report. Subst Abus (2003) 0.84
Physiological networks and disease functions of RNA-binding protein AUF1. Wiley Interdiscip Rev RNA (2014) 0.84
Dose-dependent effect of radiation on angiogenic and angiostatic CXC chemokine expression in human endothelial cells. Cytokine (2009) 0.83
Randomized trial of a computer-tailored intervention for patients with depression. Am J Health Promot (2011) 0.82
The regulation of protein synthesis in cancer. Prog Mol Biol Transl Sci (2009) 0.81
Endothelin-1 upregulates MCAM in melanocytes. J Invest Dermatol (2004) 0.78
Akt and PI3K-dependent but CREB-independent upregulation of MCAM by endothelin-3 in human melanocytes. Melanoma Res (2014) 0.77
Endothelin-1 in the tumor microenvironment correlates with melanoma invasion. Melanoma Res (2016) 0.77
Distinct function of androgen receptor coactivator ARA70α and ARA70β in mammary gland development, and in breast cancer. Breast Cancer Res Treat (2010) 0.77
Glioma-like proliferation within tissues excised as tubers in patients with tuberous sclerosis complex. Acta Neuropathol (2008) 0.75