Published in J Am Soc Nephrol on August 01, 2002
OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies. Br J Pharmacol (2012) 1.74
Physiology, structure, and regulation of the cloned organic anion transporters. Xenobiotica (2008) 1.40
Loss of epidermal growth factor receptor in vascular smooth muscle cells and cardiomyocytes causes arterial hypotension and cardiac hypertrophy. Hypertension (2012) 1.54
Nuclear shuttling precedes dimerization in mineralocorticoid receptor signaling. Chem Biol (2012) 1.50
Aldosterone stimulates surface expression of NHE3 in renal proximal brush borders. Pflugers Arch (2003) 1.47
Ca2+ but not H2O2 modulates GRE-element activation by the human mineralocorticoid receptor in HEK cells. Mol Cell Endocrinol (2006) 1.46
Nephrotoxicity of platinum complexes is related to basolateral organic cation transport. Kidney Int (2004) 1.24
Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical N(G), N(G)-dimethylarginine in human essential hypertension. Am J Hypertens (2002) 1.19
Megalin is essential for renal proximal tubule reabsorption of (111)In-DTPA-octreotide. J Nucl Med (2005) 1.07
Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs. Neoplasia (2006) 1.02
Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1) in vitro and in vivo by increasing the activity of the p-glycoprotein via activation of p38. Int J Cancer (2008) 1.02
Aldosterone-induced EGFR expression: interaction between the human mineralocorticoid receptor and the human EGFR promoter. Am J Physiol Endocrinol Metab (2007) 1.01
Albumin induces NF-kappaB expression in human proximal tubule-derived cells (IHKE-1). Cell Physiol Biochem (2002) 0.97
Aldosterone stimulates epidermal growth factor receptor expression. J Biol Chem (2003) 0.96
Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions. Mol Endocrinol (2005) 0.96
Cyclical mechanical stretch modulates expression of collagen I and collagen III by PKC and tyrosine kinase in cardiac fibroblasts. Am J Physiol Regul Integr Comp Physiol (2007) 0.95
Acidic environment leads to ROS-induced MAPK signaling in cancer cells. PLoS One (2011) 0.94
Long-term application of the aldosterone antagonist spironolactone prevents stiff endothelial cell syndrome. FASEB J (2013) 0.94
Implementation of an in vitro model system for investigation of reperfusion damage after renal ischemia. Cell Physiol Biochem (2009) 0.94
Metabolism and cytotoxic effects of T-2 toxin and its metabolites on human cells in primary culture. Toxicology (2009) 0.92
Evidence for epidermal growth factor receptor as negative-feedback control in aldosterone-induced Na+ reabsorption. Am J Physiol Renal Physiol (2004) 0.91
Inhibition of cardiac pacemaker channel hHCN2 depends on intercalation of lipopolysaccharide into channel-containing membrane microdomains. J Physiol (2013) 0.90
Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling. J Biol Chem (2002) 0.88
EF domains are sufficient for nongenomic mineralocorticoid receptor actions. J Biol Chem (2008) 0.88
Mineralocorticoid receptor inhibits CREB signaling by calcineurin activation. FASEB J (2010) 0.88
Nongenotropic aldosterone effects and the EGFR: interaction and biological relevance. Steroids (2007) 0.87
Hypoxia-induced extracellular acidosis increases p-glycoprotein activity and chemoresistance in tumors in vivo via p38 signaling pathway. Adv Exp Med Biol (2011) 0.86
Role of the tumor microenvironment in the activity and expression of the p-glycoprotein in human colon carcinoma cells. Oncol Rep (2007) 0.85
Cisplatin-induced apoptosis is enhanced by hypoxia and by inhibition of mitochondria in renal collecting duct cells. Toxicol Sci (2005) 0.85
Activity of drug efflux transporters in tumor cells under hypoxic conditions. Adv Exp Med Biol (2008) 0.84
Aldosterone stimulates activity and surface expression of NHE3 in human primary proximal tubule epithelial cells (RPTEC). Cell Physiol Biochem (2006) 0.84
Protein uptake disturbs collagen homeostasis in proximal tubule-derived cells. Kidney Int Suppl (2003) 0.84
Prostaglandin E2 inhibits its own renal transport by downregulation of organic anion transporters rOAT1 and rOAT3. J Am Soc Nephrol (2005) 0.84
Transient activation and delayed inhibition of Na+,K+,Cl- cotransport in ATP-treated C11-MDCK cells involve distinct P2Y receptor subtypes and signaling mechanisms. J Biol Chem (2006) 0.84
Long-term effects of ochratoxin A on fibrosis and cell death in human proximal tubule or fibroblast cells in primary culture. Toxicology (2006) 0.83
Short-term regulation of basolateral organic anion uptake in proximal tubular opossum kidney cells: prostaglandin E2 acts via receptor-mediated activation of protein kinase A. J Am Soc Nephrol (2003) 0.83
Colocalization of mineralocorticoid and EGF receptor at the plasma membrane. Biochim Biophys Acta (2010) 0.82
Role of epidermal growth factor receptor in vascular structure and function. Curr Opin Nephrol Hypertens (2014) 0.82
Effects of the mycotoxin deoxynivalenol on human primary hepatocytes. Mol Nutr Food Res (2008) 0.82
Impact of hypoxic and acidic extracellular conditions on cytotoxicity of chemotherapeutic drugs. Adv Exp Med Biol (2007) 0.81
Chloroacetaldehyde- and acrolein-induced death of human proximal tubule cells. Pediatr Nephrol (2005) 0.81
Activation of cell migration with fibroblast growth factor-2 requires calcium-sensitive potassium channels. Pflugers Arch (2008) 0.81
Non-classical actions of the mineralocorticoid receptor: misuse of EGF receptors? Mol Cell Endocrinol (2007) 0.81
Disturbed Ca2+-signaling by chloroacetaldehyde: a possible cause for chronic ifosfamide nephrotoxicity. Kidney Int (2005) 0.81
The nephrotoxin ochratoxin A induces key parameters of chronic interstitial nephropathy in renal proximal tubular cells. Cell Physiol Biochem (2005) 0.81
Aldosterone/NaCl-induced renal and cardiac fibrosis is modulated by TGF-β responsiveness of T cells. Hypertens Res (2011) 0.81
Mesna or cysteine prevents chloroacetaldehyde-induced cell death of human proximal tubule cells. Pediatr Nephrol (2007) 0.81
Cytotoxicity, metabolism and cellular uptake of the mycotoxin deoxynivalenol in human proximal tubule cells and lung fibroblasts in primary culture. Toxicology (2007) 0.80
Differential reduction of HCN channel activity by various types of lipopolysaccharide. J Mol Cell Cardiol (2011) 0.80
Consequences of epidermal growth factor receptor (ErbB1) loss for vascular smooth muscle cells from mice with targeted deletion of ErbB1. Arterioscler Thromb Vasc Biol (2011) 0.80
Mechanism of cell death of rat cardiac fibroblasts induced by serum depletion. Mol Cell Biochem (2003) 0.80
Exposure to nephrotoxic ochratoxin A enhances collagen secretion in human renal proximal tubular cells. Mol Nutr Food Res (2005) 0.79
A rapid screening method to test apoptotic synergisms of ochratoxin A with other nephrotoxic substances. Toxicol In Vitro (2005) 0.79
Neurotoxic potential and cellular uptake of T-2 toxin in human astrocytes in primary culture. Chem Res Toxicol (2013) 0.79
The food contaminant and nephrotoxin ochratoxin A enhances Wnt1 inducible signaling protein 1 and tumor necrosis factor-α expression in human primary proximal tubule cells. Mol Nutr Food Res (2012) 0.78
Cl- secretion in ATP-treated renal epithelial C7-MDCK cells is mediated by activation of P 2Y1 receptors, phospholipase A2 and protein kinase A. J Physiol (2005) 0.78
Impact of hypoxia-related tumor acidosis on cytotoxicity of different chemotherapeutic drugs in vitro and in vivo. Adv Exp Med Biol (2014) 0.78
Differential effect of COX1 and COX2 inhibitors on renal outcomes following ischemic acute kidney injury. Am J Nephrol (2014) 0.77
Modulation of transcriptional mineralocorticoid receptor activity by nitrosative stress. Free Radic Biol Med (2012) 0.77
Aldosterone rapidly induces leukocyte adhesion to endothelial cells: a new link between aldosterone and arteriosclerosis? Hypertension (2007) 0.77
Interaction between mineralocorticoid receptor and epidermal growth factor receptor signaling. Mol Cell Endocrinol (2011) 0.77
Acidic priming enhances metastatic potential of cancer cells. Pflugers Arch (2014) 0.77
Identification and apoptotic potential of T-2 toxin metabolites in human cells. J Agric Food Chem (2012) 0.77
Inhibition of mitochondria prevents cell death in kidney epithelial cells by intra- and extracellular acidification. Kidney Int (2003) 0.77
Chloroacetaldehyde as a sulfhydryl reagent: the role of critical thiol groups in ifosfamide nephropathy. Kidney Blood Press Res (2006) 0.76
The phosphatase calcineurin PP2BAβ mediates part of mineralocorticoid receptor transcriptional activity. FASEB J (2012) 0.76
Effect of the mycotoxin, ochratoxin A, on hormone-stimulated ion transport in a cultured cell model of the renal principal cell. Pflugers Arch (2005) 0.76
Apical expression or expression in a non polarized cell of hOAT1 inverses regulation by epidermal growth factor (EGF) as compared to basolateral hOAT1. Cell Physiol Biochem (2004) 0.76
Effect of ochratoxin A on cell survival and collagen homeostasis in human mesangial cells in primary culture. Food Chem Toxicol (2008) 0.76
Impact of extracellular acidosis on intracellular pH control and cell signaling in tumor cells. Adv Exp Med Biol (2013) 0.76
Albumin and glucose effects on cell growth parameters, albumin uptake and Na(+)/H(+)-exchanger Isoform 3 in OK cells. Cell Physiol Biochem (2003) 0.76
Mineralocorticoid receptor interaction with SP1 generates a new response element for pathophysiologically relevant gene expression. Nucleic Acids Res (2013) 0.76
Interaction between mineralocorticoid receptor and cAMP/CREB signaling. Steroids (2009) 0.76
Regulation of Expression of Renal Organic Anion Transporters OAT1 and OAT3 in a Model of Ischemia/Reperfusion Injury. Cell Physiol Biochem (2015) 0.75
Answer to comment. Toxicology (2015) 0.75
The nephrotoxic Ifosfamide-metabolite chloroacetaldehyde interferes with renal extracellular matrix homeostasis. Cell Physiol Biochem (2014) 0.75
NOS1 induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes. Basic Res Cardiol (2015) 0.75
Inhibition of mitochondria and extracellular acidification enhance achratoxin A-induced apoptosis in renal collecting duct-derived MDCK-C7 cells. Cell Physiol Biochem (2004) 0.75
Influence of aldosterone and salt or ouabain in a10 rat aorta smooth muscle cells. J Vasc Res (2012) 0.75