Published in J Biol Chem on July 26, 2002
The family feud: turning off Sp1 by Sp1-like KLF proteins. Biochem J (2005) 1.83
Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes. Mol Cell Biol (2004) 1.57
FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner. J Clin Invest (2005) 1.25
Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity. Immunity (2009) 1.22
Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor. J Biol Chem (2008) 1.10
The BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system. J Immunol (2011) 1.04
Site-specific proteolysis of the transcriptional coactivator HCF-1 can regulate its interaction with protein cofactors. Proc Natl Acad Sci U S A (2006) 1.04
The promyelocytic leukemia zinc finger protein: two decades of molecular oncology. Front Oncol (2012) 1.03
The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation. J Biol Chem (2008) 0.98
Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2. Mol Cell Biol (2004) 0.95
FHL1 interacts with oestrogen receptors and regulates breast cancer cell growth. J Cell Mol Med (2011) 0.92
Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer. Br J Cancer (2013) 0.88
FHL2 mediates tooth development and human dental pulp cell differentiation into odontoblasts, partially by interacting with Runx2. J Mol Histol (2016) 0.85
The expression pattern of FHL2 during mouse molar development. J Mol Histol (2012) 0.84
Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice. PLoS One (2010) 0.82
Immunohistochemical localization of four and a half LIM domains 2 in the odontoblasts of mature human teeth. J Mol Histol (2011) 0.79
FHL2 switches MITF from activator to repressor of Erbin expression during cardiac hypertrophy. Int J Cardiol (2015) 0.79
FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia. Blood Cancer J (2011) 0.77
FHL2 regulates hematopoietic stem cell functions under stress conditions. Leukemia (2014) 0.77
The LIM-only protein FHL2 mediates ras-induced transformation through cyclin D1 and p53 pathways. PLoS One (2008) 0.77
Interaction of TACC proteins with the FHL family: implications for ERK signaling. J Cell Commun Signal (2007) 0.76
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell (2010) 15.20
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature (2008) 10.73
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia. Nat Genet (2003) 5.16
Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. Immunity (2013) 4.08
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. Blood (2009) 4.00
The kinase domain of titin controls muscle gene expression and protein turnover. Science (2005) 3.68
S100 proteins: structure, functions and pathology. Front Biosci (2002) 3.28
Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling. Trends Cell Biol (2005) 3.14
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation. Cancer Cell (2013) 3.13
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells. Nat Med (2004) 3.10
Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev Cell (2005) 2.95
The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells. Blood (2010) 2.71
Histone deacetylase inhibitors in cancer therapy: is transcription the primary target? Cancer Cell (2003) 2.61
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. Blood (2007) 2.58
Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain. Mol Cell (2003) 2.20
Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study. Blood (2011) 2.18
Sprouty1 regulates reversible quiescence of a self-renewing adult muscle stem cell pool during regeneration. Cell Stem Cell (2010) 2.03
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. J Clin Invest (2010) 2.00
Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis. Mol Cell Biol (2003) 2.00
Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance. J Clin Invest (2010) 1.97
Sequential myofibrillar breakdown accompanies mitotic division of mammalian cardiomyocytes. J Cell Sci (2004) 1.96
WNT-3, expressed by motoneurons, regulates terminal arborization of neurotrophin-3-responsive spinal sensory neurons. Neuron (2002) 1.81
Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis. Dev Cell (2009) 1.81
miR-27b controls venous specification and tip cell fate. Blood (2011) 1.79
Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2. J Cell Sci (2002) 1.77
The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo. Genes Dev (2003) 1.73
CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors. Am J Pathol (2004) 1.72
Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors. Mol Cell Biol (2002) 1.70
Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia. Nat Med (2012) 1.69
Establishment of cardiac cytoarchitecture in the developing mouse heart. Dev Biol (2005) 1.68
Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1. Cancer Res (2004) 1.67
Branching morphogenesis of the ureteric epithelium during kidney development is coordinated by the opposing functions of GDNF and Sprouty1. Dev Biol (2006) 1.61
Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression. Mol Cell Biol (2003) 1.61
Survivin is not required for the endomitotic cell cycle of megakaryocytes. Blood (2009) 1.57
A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions. Heart Rhythm (2011) 1.54
The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. Mol Cell (2013) 1.54
Dilated cardiomyopathy: a disease of the intercalated disc? Trends Cardiovasc Med (2003) 1.52
SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant. Cancer Res (2004) 1.51
The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity. J Biol Chem (2005) 1.44
Emerging epigenetic targets and therapies in cancer medicine. Cancer Discov (2012) 1.43
From A to Z and back? Multicompartment proteins in the sarcomere. Trends Cell Biol (2005) 1.43
Kidney development in the absence of Gdnf and Spry1 requires Fgf10. PLoS Genet (2010) 1.40
Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia. Blood (2004) 1.39
PLZF is a regulator of homeostatic and cytokine-induced myeloid development. Genes Dev (2009) 1.35
A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep (2013) 1.33
Thymosin beta4 facilitates epicardial neovascularization of the injured adult heart. Ann N Y Acad Sci (2010) 1.33
An integrated genome screen identifies the Wnt signaling pathway as a major target of WT1. Proc Natl Acad Sci U S A (2009) 1.26
The sensitive giant: the role of titin-based stretch sensing complexes in the heart. Trends Cell Biol (2004) 1.26
Histone deacetylases as therapeutic targets in hematologic malignancies. Curr Opin Hematol (2002) 1.26
Subtype and prognostic classification of rhabdomyosarcoma by immunohistochemistry. J Clin Oncol (2006) 1.25
Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance. J Cell Biol (2010) 1.24
Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop. Mol Biol Cell (2004) 1.24
Deregulation of H3K27 methylation in cancer. Nat Genet (2010) 1.23
CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres. PLoS One (2011) 1.22
Prediction of chromosomal aneuploidy from gene expression data. Genes Chromosomes Cancer (2007) 1.22
Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity. Immunity (2009) 1.22
Prox1 maintains muscle structure and growth in the developing heart. Development (2008) 1.21
HOX deregulation in acute myeloid leukemia. J Clin Invest (2007) 1.20
ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein. Blood (2003) 1.19
Expression analysis of S100 proteins and RAGE in human tumors using tissue microarrays. Biochem Biophys Res Commun (2003) 1.19
WT1 induces apoptosis through transcriptional regulation of the proapoptotic Bcl-2 family member Bak. Cancer Res (2005) 1.18
Estrogen receptor alpha up-regulation and redistribution in human heart failure. FASEB J (2006) 1.18
WT1 activates a glomerular-specific enhancer identified from the human nephrin gene. J Am Soc Nephrol (2004) 1.17
Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities. Cancer Res (2008) 1.17
PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions. Exp Cell Res (2003) 1.16
Physical and functional interactions of human endogenous retrovirus proteins Np9 and rec with the promyelocytic leukemia zinc finger protein. J Virol (2007) 1.14
Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP. Exp Cell Res (2006) 1.14
Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy. Hum Mol Genet (2008) 1.13
Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family. Genomics (2002) 1.13
Targets for cancer therapy in childhood sarcomas. Cancer Treat Rev (2010) 1.12
M-band: a safeguard for sarcomere stability? J Muscle Res Cell Motil (2003) 1.12
The receptor tyrosine kinase regulator Sprouty1 is a target of the tumor suppressor WT1 and important for kidney development. J Biol Chem (2003) 1.12
Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3. Proc Natl Acad Sci U S A (2012) 1.12
Design of artificial myocardial microtissues. Tissue Eng (2004) 1.12
DNMT3A mutations in acute myeloid leukemia. Nat Genet (2011) 1.11
S100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells. Biochem Biophys Res Commun (2004) 1.11
Rhabdomyosarcoma: current challenges and their implications for developing therapies. Cold Spring Harb Perspect Med (2014) 1.10
Palladin interacts with SH3 domains of SPIN90 and Src and is required for Src-induced cytoskeletal remodeling. Exp Cell Res (2007) 1.09
Dimerisation of myomesin: implications for the structure of the sarcomeric M-band. J Mol Biol (2005) 1.09
Myomesin 3, a novel structural component of the M-band in striated muscle. J Mol Biol (2007) 1.09
CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function. J Cell Sci (2010) 1.08
The PAX5 oncogene is expressed in N-type neuroblastoma cells and increases tumorigenicity of a S-type cell line. Carcinogenesis (2004) 1.08
Involvement of palladin and alpha-actinin in targeting of the Abl/Arg kinase adaptor ArgBP2 to the actin cytoskeleton. Exp Cell Res (2005) 1.07
Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC. Blood (2009) 1.06
Sprouty proteins inhibit receptor-mediated activation of phosphatidylinositol-specific phospholipase C. Mol Biol Cell (2010) 1.06
Novel role for p90 ribosomal S6 kinase in the regulation of cardiac myofilament phosphorylation. J Biol Chem (2010) 1.05
Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells. Blood (2008) 1.04
Measles virus spreads in rat hippocampal neurons by cell-to-cell contact and in a polarized fashion. J Virol (2002) 1.04
Proteomics analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution. Mol Cell Proteomics (2009) 1.04
Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy. J Mol Cell Cardiol (2010) 1.02
Ca2+ -dependent interaction of S100A1 with the sarcoplasmic reticulum Ca2+ -ATPase2a and phospholamban in the human heart. Biochem Biophys Res Commun (2003) 1.02
Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma. Int J Cancer (2012) 1.01
Muscle Research and Gene Ontology: New standards for improved data integration. BMC Med Genomics (2009) 1.01
BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit. J Biol Chem (2003) 1.00
VEGF profiling and angiogenesis in human microtissues. J Biotechnol (2005) 1.00
Furin targeted drug delivery for treatment of rhabdomyosarcoma in a mouse model. PLoS One (2010) 1.00
PLZF induces megakaryocytic development, activates Tpo receptor expression and interacts with GATA1 protein. Oncogene (2002) 0.98
Re-expression of proteins involved in cytokinesis during cardiac hypertrophy. Exp Cell Res (2007) 0.98