Published in J Clin Immunol on July 01, 2002
Changing the energy of an immune response. Am J Clin Exp Immunol (2013) 0.88
Dietary fat modifies mitochondrial and plasma membrane apoptotic signaling in skeletal muscle of calorie-restricted mice. Age (Dordr) (2012) 0.81
Cellular metabolism as a basis for immune privilege. J Immune Based Ther Vaccines (2006) 0.79
Apoptosis by death factor. Cell (1997) 14.42
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell (1993) 14.39
The Fas death factor. Science (1995) 13.81
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature (1992) 12.92
Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell (1993) 10.83
Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell (1993) 9.06
Gene expression profile of aging and its retardation by caloric restriction. Science (1999) 8.06
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell (1994) 7.23
Features of apoptotic cells measured by flow cytometry. Cytometry (1992) 6.45
Oxidative stress as a mediator of apoptosis. Immunol Today (1994) 5.80
Double identity for proteins of the Bcl-2 family. Nature (1997) 5.60
Programmed cell death and extrathymic reduction of Vbeta8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature (1991) 5.56
Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J Immunol (1983) 5.07
Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science (1993) 4.53
The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity (1994) 4.26
The pathogenesis of autoimmunity in New Zealand black mice. Curr Top Microbiol Immunol (1974) 3.98
The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J Immunol (1992) 3.66
Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med (1994) 3.11
Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Ageing Dev (1994) 2.96
Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis. J Immunol (1999) 2.92
Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J Immunol (1994) 2.53
Effect of bcl-2 on Fas antigen-mediated cell death. J Immunol (1993) 2.50
Regulation of lymphocyte survival by the bcl-2 gene family. Annu Rev Immunol (1995) 2.48
Influence of diet on survival of mice. Proc Natl Acad Sci U S A (1976) 2.45
Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. J Clin Invest (1996) 2.07
Cell death mechanisms and the immune system. Immunol Rev (1991) 2.07
In vitro apoptosis and expression of apoptosis-related molecules in lymphocytes from patients with systemic lupus erythematosus and other autoimmune diseases. Arthritis Rheum (1997) 1.95
Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J Neurosci (1997) 1.81
bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine. Cancer Res (1995) 1.75
The cellular and subcellular bases of immunosenescence. Adv Immunol (1989) 1.59
Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice. J Clin Invest (1981) 1.58
Fas/Apo1 mutations and autoimmune lymphoproliferative syndrome in a patient with type 2 autoimmune hepatitis. Gastroenterology (1997) 1.58
Mitochondria and programmed cell death: back to the future. FEBS Lett (1996) 1.52
Influence of dietary restriction on immunologic function and renal disease in (NZB x NZW) F1 mice. Proc Natl Acad Sci U S A (1978) 1.52
Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes. Cancer Res (1996) 1.46
Correlation of increased susceptibility to apoptosis of CD4+ T cells with lymphocyte activation and activity of disease in patients with primary Sjögren's syndrome. Arthritis Rheum (1999) 1.44
Activation-induced apoptosis in lymphocytes. Curr Opin Immunol (1994) 1.34
Retinoic acids regulate apoptosis of T lymphocytes through an interplay between RAR and RXR receptors. Cell Death Differ (1998) 1.23
Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes. J Immunol (1998) 1.14
Deficiency of the Fas apoptosis pathway without Fas gene mutations in pediatric patients with autoimmunity/lymphoproliferation. Blood (1997) 1.10
Decreased pro-inflammatory cytokines and increased antioxidant enzyme gene expression by omega-3 lipids in murine lupus nephritis. Biochem Biophys Res Commun (1994) 1.09
Increased TNF-alpha-induced apoptosis in lymphocytes from aged humans: changes in TNF-alpha receptor expression and activation of caspases. J Immunol (1999) 1.08
Caloric restriction: conservation of in vivo cellular replicative capacity accompanies life-span extension in mice. Exp Cell Res (1995) 0.98
Autoimmunity and apoptosis. J Exp Med (1994) 0.97
A role for metals and free radicals in the induction of apoptosis in thymocytes. FEBS Lett (1994) 0.96
Life span is prolonged in food-restricted autoimmune-prone (NZB x NZW)F(1) mice fed a diet enriched with (n-3) fatty acids. J Nutr (2001) 0.96
Apoptosis regulated by a death factor and its receptor: Fas ligand and Fas. Philos Trans R Soc Lond B Biol Sci (1994) 0.90
Increased TGF-beta and decreased oncogene expression by omega-3 fatty acids in the spleen delays onset of autoimmune disease in B/W mice. J Immunol (1994) 0.90
Effects of administration of monoclonal antibodies (anti-CD4 or anti-CD8) on the development of autoimmune diseases in (NZW x BXSB)F1 mice. Immunobiology (1998) 0.89
Increased expression of functional Fas-ligand in activated T cells from patients with systemic lupus erythematosus. Autoimmunity (1997) 0.89
Exercise and diet modulate cardiac lipid peroxidation and antioxidant defenses. Free Radic Biol Med (1996) 0.86
Inhibition of Fas-induced apoptosis by Bcl-2. Oncogene (1998) 0.84
Dietary (n-6) and (n-3) fatty acids and energy restriction modulate mesenteric lymph node lymphocyte function in autoimmune-prone (NZB x NZW)F1 mice. J Nutr (2000) 0.84
Effects of calorie restriction on transforming growth factor beta 1 and proinflammatory cytokines in murine Sjogren's syndrome. Clin Immunol Immunopathol (1995) 0.83
Modulation of gene expression in autoimmune disease and aging by food restriction and dietary lipids. Proc Soc Exp Biol Med (1990) 0.83
Maintenance of NF-kappaB activation in T-lymphocytes and a naive T-cell population in autoimmune-prone (NZB/NZW)F(1) mice by feeding a food-restricted diet enriched with n-3 fatty acids. Cell Immunol (2001) 0.82
Dietary lipids and calorie restriction affect mammary tumor incidence and gene expression in mouse mammary tumor virus/v-Ha-ras transgenic mice. Proc Natl Acad Sci U S A (1995) 0.82
Modulation of antioxidant enzymes and apoptosis in mice by dietary lipids and treadmill exercise. J Clin Immunol (1999) 0.82
Effects of energy intake on type 1 plasminogen activator inhibitor levels in glomeruli of lupus-prone B/W mice. Am J Pathol (1995) 0.80
Increased lymphocyte apoptosis in Fas ligand transgenic mice. J Immunol (1997) 0.80
Treatment of lupus in NZB/W F1 mice with monoclonal antibody against Fas ligand. J Autoimmun (2000) 0.79
Modulation of antioxidant activities and immune response by food restriction in aging Fisher-344 rats. Aging (Milano) (1995) 0.78
Induction of apoptosis and apoptotic mediators in Balb/C splenic lymphocytes by dietary n-3 and n-6 fatty acids. Lipids (1999) 0.78
Differential expression of Fas antigen and Bcl-2 protein on CD4+ T cells, CD8+ T cells, and monocytes. Cell Immunol (1995) 0.77
Calorie restriction decreases platelet-derived growth factor (PDGF)-A and thrombin receptor mRNA expression in autoimmune murine lupus nephritis. Clin Exp Immunol (1997) 0.77
Lymphocyte apoptosis and apoptosis-associated gene expression in Sjögren's syndrome. Arthritis Rheum (1996) 0.77
Modulation of oxidative DNA damage levels by dietary fat and calories. Mutat Res (1993) 0.75
Biological effects of conjugated linoleic acids in health and disease. J Nutr Biochem (2006) 1.60
Dietary n-3 fatty acids decrease osteoclastogenesis and loss of bone mass in ovariectomized mice. J Bone Miner Res (2003) 1.38
High fat diet-induced animal model of age-associated obesity and osteoporosis. J Nutr Biochem (2010) 1.36
Docosahexaenoic acid-enriched fish oil attenuates kidney disease and prolongs median and maximal life span of autoimmune lupus-prone mice. J Immunol (2010) 1.22
Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice. Exp Gerontol (2010) 1.20
CC chemokine receptor 5 influences late-stage atherosclerosis. Atherosclerosis (2007) 1.16
Docosahexaenoic acid is more potent inhibitor of osteoclast differentiation in RAW 264.7 cells than eicosapentaenoic acid. J Cell Physiol (2008) 1.12
Inhibition of inflammatory response in transgenic fat-1 mice on a calorie-restricted diet. Biochem Biophys Res Commun (2006) 1.07
Fish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth. Breast Cancer Res Treat (2008) 1.06
Conjugated linoleic acid inhibits osteoclast differentiation of RAW264.7 cells by modulating RANKL signaling. J Lipid Res (2006) 1.01
Endogenous n-3 fatty acids protect ovariectomy induced bone loss by attenuating osteoclastogenesis. J Cell Mol Med (2009) 0.99
Effect of fish oil on bone mineral density in aging C57BL/6 female mice. J Nutr Biochem (2006) 0.97
Anti-inflammatory action of dietary fish oil and calorie restriction. Life Sci (2006) 0.96
Effect of dietary n-3 and n-6 oils with and without food restriction on activity of antioxidant enzymes and lipid peroxidation in livers of cyclophosphamide treated autoimmune-prone NZB/W female mice. J Am Coll Nutr (2003) 0.94
Differential effects of conjugated linoleic acid isomers in insulin-resistant female C57Bl/6J mice. J Nutr Biochem (2009) 0.94
Different ratios of eicosapentaenoic and docosahexaenoic omega-3 fatty acids in commercial fish oils differentially alter pro-inflammatory cytokines in peritoneal macrophages from C57BL/6 female mice. J Nutr Biochem (2006) 0.90
The combination of dietary conjugated linoleic acid and treadmill exercise lowers gain in body fat mass and enhances lean body mass in high fat-fed male Balb/C mice. J Nutr (2005) 0.90
Phellodendron amurense bark extract prevents progression of prostate tumors in transgenic adenocarcinoma of mouse prostate: potential for prostate cancer management. Anticancer Res (2010) 0.90
Regulation of immune function by calorie restriction and cyclophosphamide treatment in lupus-prone NZB/NZW F1 mice. Cell Immunol (2004) 0.89
Effects of n-3 fatty acids on autoimmunity and osteoporosis. Front Biosci (2008) 0.88
Alternative therapies for the prevention and treatment of osteoporosis. Nutr Rev (2012) 0.88
Inhibition of osteoporosis in autoimmune disease prone MRL/Mpj-Fas(lpr) mice by N-3 fatty acids. J Am Coll Nutr (2005) 0.88
Conjugated linoleic acid protects against age-associated bone loss in C57BL/6 female mice. J Nutr Biochem (2006) 0.87
The mechanism of the enhanced antioxidant effects against superoxide anion radicals of reduced water produced by electrolysis. Biophys Chem (2004) 0.87
The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. Oxid Med Cell Longev (2010) 0.87
Food restriction and fish oil suppress atherogenic risk factors in lupus-prone (NZB x NZW) F1 mice. J Clin Immunol (2003) 0.86
DHA is a more potent inhibitor of breast cancer metastasis to bone and related osteolysis than EPA. Breast Cancer Res Treat (2013) 0.85
Effects of conjugated linoleic acid and exercise on bone mass in young male Balb/C mice. Lipids Health Dis (2006) 0.85
Conjugated linoleic acid and chromium lower body weight and visceral fat mass in high-fat-diet-fed mice. Lipids (2006) 0.85
Glutathione peroxidase activity in selenium-deficient rat liver. 1976. Biochem Biophys Res Commun (2012) 0.85
Beneficial effects of conjugated linoleic acid and exercise on bone of middle-aged female mice. J Bone Miner Metab (2008) 0.84
Conjugated linoleic acid (CLA) prevents age-associated skeletal muscle loss. Biochem Biophys Res Commun (2009) 0.84
Lovastatin inhibits bone marrow-derived dendritic cell maturation and upregulates proinflammatory cytokine production. Cell Immunol (2003) 0.84
Combination of conjugated linoleic acid with fish oil prevents age-associated bone marrow adiposity in C57Bl/6J mice. J Nutr Biochem (2010) 0.83
Effect of CLA isomers and their mixture on aging C57Bl/6J mice. Eur J Nutr (2009) 0.83
t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposity. J Cell Physiol (2011) 0.82
Fish oil concentrate delays sensitivity to thermal nociception in mice. Pharmacol Res (2011) 0.80
Concentrated fish oil (Lovaza(R)) extends lifespan and attenuates kidney disease in lupus-prone short-lived (NZBxNZW)F1 mice. Exp Biol Med (Maywood) (2013) 0.80
An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: the GRACE-IMMUNE study. BMC Med (2010) 0.79
The modulation of prostate cancer risk with alpha-tocopherol: a pilot randomized, controlled clinical trial. J Urol (2005) 0.79
Fish oil decreases inflammation and reduces cardiac remodeling in rosiglitazone treated aging mice. Pharmacol Res (2010) 0.78
Age associated alterations in costimulatory and adhesion molecule expression in lupus-prone mice are attenuated by food restriction with n-6 and n-3 fatty acids. J Clin Immunol (2004) 0.77
Dietary coral calcium and zeolite protects bone in a mouse model for postmenopausal bone loss. Nutr Res (2012) 0.77
Endogenously produced n-3 fatty acids protect against ovariectomy induced bone loss in fat-1 transgenic mice. J Bone Miner Metab (2010) 0.77
Inhibition of H2O2-induced apoptosis of lymphocytes by calorie restriction during aging. Microsc Res Tech (2002) 0.77
Inhibition of Bone Loss by Cissus quadrangularis in Mice: A Preliminary Report. J Osteoporos (2012) 0.77
Conjugated linoleic Acid prevents ovariectomy-induced bone loss in mice by modulating both osteoclastogenesis and osteoblastogenesis. Lipids (2013) 0.75