Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair.

PubWeight™: 3.04‹?› | Rank: Top 1%

🔗 View Article (PMID 12154119)

Published in Genes Dev on August 01, 2002

Authors

Satya Prakash1, Louise Prakash

Author Affiliations

1: Sealy Center for Molecular Science, University of Texas Medical Branch, Galveston, Texas 77555-1061, USA.

Articles citing this

(truncated to the top 100)

Homologous recombination in DNA repair and DNA damage tolerance. Cell Res (2008) 3.86

Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism. Microbiol Mol Biol Rev (2004) 3.67

Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Microbiol Mol Biol Rev (2009) 3.62

Inhibition of mutation and combating the evolution of antibiotic resistance. PLoS Biol (2005) 3.47

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res (2008) 3.15

Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis. EMBO J (2003) 2.69

Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1. Proc Natl Acad Sci U S A (2005) 2.62

Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae. Mol Cell Biol (2004) 2.49

Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. EMBO J (2009) 2.37

Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site. EMBO J (2004) 2.14

The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase. Proc Natl Acad Sci U S A (2006) 1.92

DNA interstrand crosslink repair during G1 involves nucleotide excision repair and DNA polymerase zeta. EMBO J (2006) 1.89

Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis. Proc Natl Acad Sci U S A (2006) 1.86

The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm. Mol Cell Biol (2004) 1.68

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling. EMBO J (2006) 1.65

The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex. Mol Cell Biol (2006) 1.65

Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa. Mol Cell Biol (2004) 1.64

Evolving views of DNA replication (in)fidelity. Cold Spring Harb Symp Quant Biol (2009) 1.62

Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions. Mol Cell Biol (2006) 1.61

The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins. Nucleic Acids Res (2006) 1.57

DNA repair deficiency in neurodegeneration. Prog Neurobiol (2011) 1.55

Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. Mol Cell Biol (2009) 1.54

DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ. J Biol Chem (2012) 1.50

Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta. Mol Cell Biol (2004) 1.47

Defining the position of the switches between replicative and bypass DNA polymerases. EMBO J (2004) 1.44

The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast. Nucleic Acids Res (2004) 1.41

A novel function of DNA polymerase zeta regulated by PCNA. EMBO J (2006) 1.40

Mutational specificity and genetic control of replicative bypass of an abasic site in yeast. Proc Natl Acad Sci U S A (2008) 1.39

Complex formation of yeast Rev1 and Rev7 proteins: a novel role for the polymerase-associated domain. Mol Cell Biol (2005) 1.33

Enzymatic switching for efficient and accurate translesion DNA replication. Nucleic Acids Res (2004) 1.30

TOR signaling is a determinant of cell survival in response to DNA damage. Mol Cell Biol (2007) 1.28

Yeast DNA polymerase zeta is an efficient extender of primer ends opposite from 7,8-dihydro-8-Oxoguanine and O6-methylguanine. Mol Cell Biol (2003) 1.22

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Nat Struct Mol Biol (2010) 1.21

Circadian clock control of the cellular response to DNA damage. FEBS Lett (2010) 1.20

Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa. Mol Cell Biol (2005) 1.19

Disruption of the AtREV3 gene causes hypersensitivity to ultraviolet B light and gamma-rays in Arabidopsis: implication of the presence of a translesion synthesis mechanism in plants. Plant Cell (2003) 1.17

REV1 restrains DNA polymerase zeta to ensure frame fidelity during translesion synthesis of UV photoproducts in vivo. Nucleic Acids Res (2008) 1.15

A role for yeast and human translesion synthesis DNA polymerases in promoting replication through 3-methyl adenine. Mol Cell Biol (2007) 1.15

Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae. Genetics (2009) 1.14

The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. Mol Cell Biol (2005) 1.14

The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination. Biochemistry (2006) 1.13

Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance. Nucleic Acids Res (2012) 1.10

Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase iota. Proc Natl Acad Sci U S A (2005) 1.09

Roles of Saccharomyces cerevisiae DNA polymerases Poleta and Polzeta in response to irradiation by simulated sunlight. Nucleic Acids Res (2003) 1.09

Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. BMC Biol (2004) 1.08

Complex formation of yeast Rev1 with DNA polymerase eta. Mol Cell Biol (2007) 1.06

A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair. Genes Dev (2003) 1.05

Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis. Biochemistry (2008) 1.05

Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase eta. Biochemistry (2008) 1.04

Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA. Proc Natl Acad Sci U S A (2011) 1.04

Roles of Arabidopsis AtREV1 and AtREV7 in translesion synthesis. Plant Physiol (2005) 1.03

Processing of DNA lesions by archaeal DNA polymerases from Sulfolobus solfataricus. Nucleic Acids Res (2003) 1.02

PCNA structure and function: insights from structures of PCNA complexes and post-translationally modified PCNA. Subcell Biochem (2012) 1.01

The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability. Mutat Res (2012) 0.99

The mismatch repair system promotes DNA polymerase zeta-dependent translesion synthesis in yeast. Proc Natl Acad Sci U S A (2009) 0.99

Human DNA polymerase kappa uses template-primer misalignment as a novel means for extending mispaired termini and for generating single-base deletions. Genes Dev (2003) 0.98

Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini. Proc Natl Acad Sci U S A (2006) 0.97

The in vivo characterization of translesion synthesis across UV-induced lesions in Saccharomyces cerevisiae: insights into Pol zeta- and Pol eta-dependent frameshift mutagenesis. Genetics (2005) 0.96

A single domain in human DNA polymerase iota mediates interaction with PCNA: implications for translesion DNA synthesis. Mol Cell Biol (2005) 0.96

Lesion bypass by S. cerevisiae Pol ζ alone. DNA Repair (Amst) (2011) 0.95

Chemical synthesis and translesion replication of a cis-syn cyclobutane thymine-uracil dimer. Nucleic Acids Res (2004) 0.94

Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase zeta. Nucleic Acids Res (2009) 0.94

Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity. J Immunol (2012) 0.94

Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis. Biochemistry (2014) 0.93

Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link. EMBO J (2015) 0.93

Role of the ubiquitin-binding domain of Polη in Rad18-independent translesion DNA synthesis in human cell extracts. Nucleic Acids Res (2010) 0.93

Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene. Nucleic Acids Res (2003) 0.93

Mutator phenotypes due to DNA replication infidelity. Semin Cancer Biol (2010) 0.93

Essential functions of iron-requiring proteins in DNA replication, repair and cell cycle control. Protein Cell (2014) 0.92

Regulation of error-prone translesion synthesis by Spartan/C1orf124. Nucleic Acids Res (2012) 0.92

Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites. Mol Biol Cell (2011) 0.92

Two distinct translesion synthesis pathways across a lipid peroxidation-derived DNA adduct in mammalian cells. J Biol Chem (2008) 0.92

DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae. Environ Mol Mutagen (2012) 0.92

Multiple functions of DNA polymerases. CRC Crit Rev Plant Sci (2007) 0.92

Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent. DNA Repair (Amst) (2008) 0.91

In vitro replication studies of carboxymethylated DNA lesions with Saccharomyces cerevisiae polymerase η. Biochemistry (2011) 0.90

Processivity factor of DNA polymerase and its expanding role in normal and translesion DNA synthesis. Biochim Biophys Acta (2009) 0.89

Translesion synthesis across 1,N6-(2-hydroxy-3-hydroxymethylpropan-1,3-diyl)-2'-deoxyadenosine (1,N6-γ-HMHP-dA) adducts by human and archebacterial DNA polymerases. J Biol Chem (2012) 0.88

2'-deoxyribonolactone lesion produces G->A transitions in Escherichia coli. Nucleic Acids Res (2004) 0.88

Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct. Carcinogenesis (2014) 0.87

dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants. Proc Natl Acad Sci U S A (2015) 0.86

RNA∶DNA hybrids initiate quasi-palindrome-associated mutations in highly transcribed yeast DNA. PLoS Genet (2013) 0.86

Quantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis. Nucleic Acids Res (2010) 0.85

PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}. J Biochem (2009) 0.85

The C-terminal domain of human Rev1 contains independent binding sites for DNA polymerase η and Rev7 subunit of polymerase ζ. FEBS Lett (2012) 0.84

8-Hydroxyguanine: From its discovery in 1983 to the present status. Proc Jpn Acad Ser B Phys Biol Sci (2006) 0.84

Error-prone DNA repair activity during somatic hypermutation in shark B lymphocytes. J Immunol (2010) 0.84

PCNA trimer instability inhibits translesion synthesis by DNA polymerase η and by DNA polymerase δ. DNA Repair (Amst) (2013) 0.83

Pre-steady state kinetic studies show that an abasic site is a cognate lesion for the yeast Rev1 protein. DNA Repair (Amst) (2011) 0.82

8-Hydroxyguanine in a mutational hotspot of the c-Ha-ras gene causes misreplication, 'action-at-a-distance' mutagenesis and inhibition of replication. Nucleic Acids Res (2003) 0.82

An archaeal family-B DNA polymerase variant able to replicate past DNA damage: occurrence of replicative and translesion synthesis polymerases within the B family. Nucleic Acids Res (2014) 0.82

Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replication of (5'S)-8,5'-cyclopurine-2'-deoxynucleosides in vitro by DNA polymerase IV, exo-free Klenow fragment, and Dpo4. Chem Res Toxicol (2014) 0.81

Accurate and efficient bypass of 8,5'-cyclopurine-2'-deoxynucleosides by human and yeast DNA polymerase η. Chem Res Toxicol (2012) 0.81

Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation. J Nucleic Acids (2010) 0.81

Evidence for base excision repair processing of DNA interstrand crosslinks. Mutat Res (2012) 0.80

DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2015) 0.80

Lesion bypass DNA polymerases replicate across non-DNA segments. Proc Natl Acad Sci U S A (2003) 0.80

FF483-484 motif of human Polη mediates its interaction with the POLD2 subunit of Polδ and contributes to DNA damage tolerance. Nucleic Acids Res (2015) 0.80

A novel variant of DNA polymerase ζ, Rev3ΔC, highlights differential regulation of Pol32 as a subunit of polymerase δ versus ζ in Saccharomyces cerevisiae. DNA Repair (Amst) (2014) 0.79

Substitution of a residue contacting the triphosphate moiety of the incoming nucleotide increases the fidelity of yeast DNA polymerase zeta. Nucleic Acids Res (2008) 0.79

Articles by these authors

Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu Rev Biochem (2005) 8.13

Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature (2004) 3.57

Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression. Mol Cell (2007) 3.51

Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae. Mol Cell Biol (2004) 2.49

Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Mol Cell (2007) 2.46

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta. Nat Struct Mol Biol (2009) 2.44

Requirement of RAD5 and MMS2 for postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae. Mol Cell Biol (2002) 2.37

Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science (2005) 2.37

Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA. Mol Cell Biol (2002) 2.15

Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen. Proc Natl Acad Sci U S A (2006) 2.06

Yeast Rev1 protein is a G template-specific DNA polymerase. J Biol Chem (2002) 1.86

Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis. Proc Natl Acad Sci U S A (2006) 1.86

Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair. Structure (2005) 1.80

Structural basis for the suppression of skin cancers by DNA polymerase eta. Nature (2010) 1.73

Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase. Structure (2008) 1.72

Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme. Proc Natl Acad Sci U S A (2008) 1.71

Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Proc Natl Acad Sci U S A (2008) 1.66

Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa. Mol Cell Biol (2004) 1.64

Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells. Proc Natl Acad Sci U S A (2009) 1.62

Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions. Mol Cell Biol (2006) 1.61

Mms2-Ubc13-dependent and -independent roles of Rad5 ubiquitin ligase in postreplication repair and translesion DNA synthesis in Saccharomyces cerevisiae. Mol Cell Biol (2006) 1.61

Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini. Proc Natl Acad Sci U S A (2002) 1.59

Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nat Struct Mol Biol (2006) 1.58

Role of human DNA polymerase kappa as an extender in translesion synthesis. Proc Natl Acad Sci U S A (2002) 1.51

Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ. Proc Natl Acad Sci U S A (2012) 1.50

Yeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycol. Genes Dev (2003) 1.48

Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis. Proc Natl Acad Sci U S A (2008) 1.47

Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta. Mol Cell Biol (2004) 1.47

Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase eta. Proc Natl Acad Sci U S A (2003) 1.45

Requirement of RAD52 group genes for postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae. Mol Cell Biol (2007) 1.42

Translesion synthesis past acrolein-derived DNA adduct, gamma -hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta. J Biol Chem (2002) 1.40

Mutational specificity and genetic control of replicative bypass of an abasic site in yeast. Proc Natl Acad Sci U S A (2008) 1.39

Crystal structure of the catalytic core of human DNA polymerase kappa. Structure (2004) 1.35

Yeast and human translesion DNA synthesis polymerases: expression, purification, and biochemical characterization. Methods Enzymol (2006) 1.34

Complex formation of yeast Rev1 and Rev7 proteins: a novel role for the polymerase-associated domain. Mol Cell Biol (2005) 1.33

An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure (2006) 1.31

Requirement of Watson-Crick hydrogen bonding for DNA synthesis by yeast DNA polymerase eta. Mol Cell Biol (2003) 1.27

Requirement of yeast RAD2, a homolog of human XPG gene, for efficient RNA polymerase II transcription. implications for Cockayne syndrome. Cell (2002) 1.27

Error-free replicative bypass of (6-4) photoproducts by DNA polymerase zeta in mouse and human cells. Genes Dev (2010) 1.26

Dpo4 is hindered in extending a G.T mismatch by a reverse wobble. Nat Struct Mol Biol (2004) 1.24

Yeast DNA polymerase zeta is an efficient extender of primer ends opposite from 7,8-dihydro-8-Oxoguanine and O6-methylguanine. Mol Cell Biol (2003) 1.22

The stalling of transcription at abasic sites is highly mutagenic. Mol Cell Biol (2003) 1.22

Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa. Mol Cell Biol (2005) 1.19

Human DNA polymerase iota utilizes different nucleotide incorporation mechanisms dependent upon the template base. Mol Cell Biol (2004) 1.19

A role for yeast and human translesion synthesis DNA polymerases in promoting replication through 3-methyl adenine. Mol Cell Biol (2007) 1.15

Yeast DNA polymerase eta makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate. Proc Natl Acad Sci U S A (2003) 1.12

Structure of the human Rev1-DNA-dNTP ternary complex. J Mol Biol (2009) 1.12

Trf4 and Trf5 proteins of Saccharomyces cerevisiae exhibit poly(A) RNA polymerase activity but no DNA polymerase activity. Mol Cell Biol (2005) 1.12

ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol (2007) 1.09

Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase iota. Proc Natl Acad Sci U S A (2005) 1.09

Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. PLoS One (2009) 1.09

Requirement of yeast Rad1-Rad10 nuclease for the removal of 3'-blocked termini from DNA strand breaks induced by reactive oxygen species. Genes Dev (2004) 1.08

Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa. Mol Cell Biol (2006) 1.08

Yeast Rev1 protein promotes complex formation of DNA polymerase zeta with Pol32 subunit of DNA polymerase delta. Proc Natl Acad Sci U S A (2009) 1.07

Complex formation of yeast Rev1 with DNA polymerase eta. Mol Cell Biol (2007) 1.06

PCNA binding domains in all three subunits of yeast DNA polymerase δ modulate its function in DNA replication. Proc Natl Acad Sci U S A (2011) 1.06

Stimulation of 3'-->5' exonuclease and 3'-phosphodiesterase activities of yeast apn2 by proliferating cell nuclear antigen. Mol Cell Biol (2002) 1.06

Role of DNA damage-induced replication checkpoint in promoting lesion bypass by translesion synthesis in yeast. Genes Dev (2009) 1.06

Human DNA polymerase iota promotes replication through a ring-closed minor-groove adduct that adopts a syn conformation in DNA. Mol Cell Biol (2005) 1.06

Yeast RAD26, a homolog of the human CSB gene, functions independently of nucleotide excision repair and base excision repair in promoting transcription through damaged bases. Mol Cell Biol (2002) 1.06

Requirement of ELC1 for RNA polymerase II polyubiquitylation and degradation in response to DNA damage in Saccharomyces cerevisiae. Mol Cell Biol (2006) 1.05

A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair. Genes Dev (2003) 1.05

Complex formation with damage recognition protein Rad14 is essential for Saccharomyces cerevisiae Rad1-Rad10 nuclease to perform its function in nucleotide excision repair in vivo. Mol Cell Biol (2006) 1.05

Requirement of Rad5 for DNA polymerase zeta-dependent translesion synthesis in Saccharomyces cerevisiae. Genetics (2008) 1.05

Mutations in the ubiquitin binding UBZ motif of DNA polymerase eta do not impair its function in translesion synthesis during replication. Mol Cell Biol (2007) 1.05

DNA synthesis across an abasic lesion by human DNA polymerase iota. Structure (2009) 1.04

Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy. Nat Struct Mol Biol (2012) 1.02

Structural insights into yeast DNA polymerase delta by small angle X-ray scattering. J Mol Biol (2009) 1.02

Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells. Proc Natl Acad Sci U S A (2010) 1.02

The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. Mol Cell Biol (2003) 1.01

Human DNA polymerase kappa uses template-primer misalignment as a novel means for extending mispaired termini and for generating single-base deletions. Genes Dev (2003) 0.98

DNA polymerase eta lacking the ubiquitin-binding domain promotes replicative lesion bypass in humans cells. Proc Natl Acad Sci U S A (2010) 0.97

Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini. Proc Natl Acad Sci U S A (2006) 0.97

Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase eta. Proc Natl Acad Sci U S A (2005) 0.97

A single domain in human DNA polymerase iota mediates interaction with PCNA: implications for translesion DNA synthesis. Mol Cell Biol (2005) 0.96

Replication across template T/U by human DNA polymerase-iota. Structure (2009) 0.94

Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase η. Structure (2010) 0.92

Human DNA polymerase η is pre-aligned for dNTP binding and catalysis. J Mol Biol (2011) 0.91

A role for DNA polymerase θ in promoting replication through oxidative DNA lesion, thymine glycol, in human cells. J Biol Chem (2014) 0.90

Requirement of Rad18 protein for replication through DNA lesions in mouse and human cells. Proc Natl Acad Sci U S A (2012) 0.89

Role of hoogsteen edge hydrogen bonding at template purines in nucleotide incorporation by human DNA polymerase iota. Mol Cell Biol (2006) 0.87

The architecture of yeast DNA polymerase ζ. Cell Rep (2013) 0.87

Requirement of Nse1, a subunit of the Smc5-Smc6 complex, for Rad52-dependent postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae. Mol Cell Biol (2007) 0.85

DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. J Mol Biol (2010) 0.85

Deoxynucleotide triphosphate binding mode conserved in Y family DNA polymerases. Mol Cell Biol (2003) 0.85

Requirement of replication checkpoint protein kinases Mec1/Rad53 for postreplication repair in yeast. MBio (2011) 0.83

Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer. J Mol Biol (2011) 0.81

Identification of two functional PCNA-binding domains in human DNA polymerase κ. Genes Cells (2014) 0.78

Genetic control of translesion synthesis on leading and lagging DNA strands in plasmids derived from Epstein-Barr virus in human cells. MBio (2012) 0.78

A novel ubiquitin binding mode in the S. cerevisiae translesion synthesis DNA polymerase η. Mol Biosyst (2011) 0.77