Published in Structure on April 01, 2006
Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells. Proc Natl Acad Sci U S A (2009) 1.62
Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal. Chem Res Toxicol (2009) 1.38
Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota. EMBO J (2009) 1.33
Translesion DNA polymerases. Cold Spring Harb Perspect Biol (2013) 1.33
Lesion bypass of N2-ethylguanine by human DNA polymerase iota. J Biol Chem (2008) 1.28
A role for yeast and human translesion synthesis DNA polymerases in promoting replication through 3-methyl adenine. Mol Cell Biol (2007) 1.15
Structure of the human Rev1-DNA-dNTP ternary complex. J Mol Biol (2009) 1.12
Variations on a theme: eukaryotic Y-family DNA polymerases. Biochim Biophys Acta (2009) 1.10
Structural diversity of the Y-family DNA polymerases. Biochim Biophys Acta (2010) 1.10
DNA synthesis across an abasic lesion by human DNA polymerase iota. Structure (2009) 1.04
Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota. Proc Natl Acad Sci U S A (2011) 1.03
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. EMBO J (2010) 0.98
DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesions. Curr Opin Struct Biol (2011) 0.96
Replication across template T/U by human DNA polymerase-iota. Structure (2009) 0.94
Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota. J Biol Chem (2010) 0.94
DNA adduct structure-function relationships: comparing solution with polymerase structures. Chem Res Toxicol (2007) 0.94
Separate roles of structured and unstructured regions of Y-family DNA polymerases. Adv Protein Chem Struct Biol (2009) 0.93
Human DNA polymerase η is pre-aligned for dNTP binding and catalysis. J Mol Biol (2011) 0.91
Biochemical analysis of six genetic variants of error-prone human DNA polymerase ι involved in translesion DNA synthesis. Chem Res Toxicol (2014) 0.90
Kinetic analysis of base-pairing preference for nucleotide incorporation opposite template pyrimidines by human DNA polymerase iota. J Mol Biol (2009) 0.89
Recent insight into the kinetic mechanisms and conformational dynamics of Y-Family DNA polymerases. Biochemistry (2014) 0.88
Role of hoogsteen edge hydrogen bonding at template purines in nucleotide incorporation by human DNA polymerase iota. Mol Cell Biol (2006) 0.87
Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing? Biochemistry (2009) 0.86
Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases. J Biol Chem (2012) 0.84
Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer. J Mol Biol (2011) 0.81
Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chem Res Toxicol (2012) 0.80
Identification of two functional PCNA-binding domains in human DNA polymerase κ. Genes Cells (2014) 0.78
Influence of local sequence context on damaged base conformation in human DNA polymerase iota: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion. Nucleic Acids Res (2009) 0.78
Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase ι. J Biol Chem (2016) 0.78
Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι. Sci Rep (2017) 0.75
Mouse DNA polymerase ι lacking the forty-two amino acids encoded by exon-2 is catalytically inactive in vitro. DNA Repair (Amst) (2016) 0.75
Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu Rev Biochem (2005) 8.13
The break-even point: when medical advances are less important than improving the fidelity with which they are delivered. Ann Fam Med (2005) 3.84
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature (2003) 3.72
Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature (2004) 3.57
Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression. Mol Cell (2007) 3.51
Functional specificity of a Hox protein mediated by the recognition of minor groove structure. Cell (2007) 3.34
Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase. Mol Cell (2002) 3.28
Gonorrhea and chlamydia in the United States among persons 14 to 39 years of age, 1999 to 2002. Ann Intern Med (2007) 3.20
Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair. Genes Dev (2002) 3.04
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature (2010) 2.91
Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae. Mol Cell Biol (2004) 2.49
Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Mol Cell (2007) 2.46
Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta. Nat Struct Mol Biol (2009) 2.44
Requirement of RAD5 and MMS2 for postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae. Mol Cell Biol (2002) 2.37
Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science (2005) 2.37
Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA. Mol Cell Biol (2002) 2.15
Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen. Proc Natl Acad Sci U S A (2006) 2.06
The health impact of resolving racial disparities: an analysis of US mortality data. Am J Public Health (2004) 1.98
Population-based genetic and evolutionary analysis of Chlamydia trachomatis urogenital strain variation in the United States. J Bacteriol (2004) 1.94
Risk factors for Plantar fasciitis: a matched case-control study. J Bone Joint Surg Am (2003) 1.92
Giving everyone the health of the educated: an examination of whether social change would save more lives than medical advances. Am J Public Health (2007) 1.90
Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis. Proc Natl Acad Sci U S A (2006) 1.86
Yeast Rev1 protein is a G template-specific DNA polymerase. J Biol Chem (2002) 1.86
Head-to-head multicenter comparison of DNA probe and nucleic acid amplification tests for Chlamydia trachomatis infection in women performed with an improved reference standard. J Clin Microbiol (2002) 1.85
Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair. Structure (2005) 1.80
Structural basis for the suppression of skin cancers by DNA polymerase eta. Nature (2010) 1.73
Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase. Structure (2008) 1.72
Seroprevalence and coinfection with herpes simplex virus type 1 and type 2 in the United States, 1988-1994. J Infect Dis (2002) 1.72
Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme. Proc Natl Acad Sci U S A (2008) 1.71
The relative importance of patient-reported barriers to colorectal cancer screening. Am J Prev Med (2010) 1.68
Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination. Proc Natl Acad Sci U S A (2008) 1.66
Crystal structure of PU.1/IRF-4/DNA ternary complex. Mol Cell (2002) 1.64
Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa. Mol Cell Biol (2004) 1.64
BstYI bound to noncognate DNA reveals a "hemispecific" complex: implications for DNA scanning. Structure (2007) 1.63
Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells. Proc Natl Acad Sci U S A (2009) 1.62
Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions. Mol Cell Biol (2006) 1.61
Mms2-Ubc13-dependent and -independent roles of Rad5 ubiquitin ligase in postreplication repair and translesion DNA synthesis in Saccharomyces cerevisiae. Mol Cell Biol (2006) 1.61
Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini. Proc Natl Acad Sci U S A (2002) 1.59
Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nat Struct Mol Biol (2006) 1.58
Crystal structure of the SF3 helicase from adeno-associated virus type 2. Structure (2003) 1.56
Title VII funding and physician practice in rural or low-income areas. J Rural Health (2005) 1.54
Role of human DNA polymerase kappa as an extender in translesion synthesis. Proc Natl Acad Sci U S A (2002) 1.51
Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ. Proc Natl Acad Sci U S A (2012) 1.50
Interactive preventive health record to enhance delivery of recommended care: a randomized trial. Ann Fam Med (2012) 1.49
Yeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycol. Genes Dev (2003) 1.48
Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis. Proc Natl Acad Sci U S A (2008) 1.47
Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta. Mol Cell Biol (2004) 1.47