Published in J Physiol on August 01, 2002
Mitochondria-derived reactive oxygen species dilate cerebral arteries by activating Ca2+ sparks. Circ Res (2005) 2.29
Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heart. J Physiol (2003) 2.09
Muscle KATP channels: recent insights to energy sensing and myoprotection. Physiol Rev (2010) 2.06
Evidence for mitochondrial K+ channels and their role in cardioprotection. Circ Res (2004) 2.06
Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function. Antioxid Redox Signal (2009) 1.89
The role of mitochondria in protection of the heart by preconditioning. Biochim Biophys Acta (2007) 1.74
The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration. J Physiol (2002) 1.68
Multiprotein complex containing succinate dehydrogenase confers mitochondrial ATP-sensitive K+ channel activity. Proc Natl Acad Sci U S A (2004) 1.60
Cardioprotection and mitochondrial S-nitrosation: effects of S-nitroso-2-mercaptopropionyl glycine (SNO-MPG) in cardiac ischemia-reperfusion injury. J Mol Cell Cardiol (2007) 1.59
Mitochondria and Ca(2+) signaling: old guests, new functions. Pflugers Arch (2007) 1.47
Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria. J Physiol (2003) 1.43
Halothane, isoflurane and sevoflurane inhibit NADH:ubiquinone oxidoreductase (complex I) of cardiac mitochondria. J Physiol (2002) 1.41
Biochemical dysfunction in heart mitochondria exposed to ischaemia and reperfusion. Biochem J (2005) 1.40
Potential therapeutic benefits of strategies directed to mitochondria. Antioxid Redox Signal (2010) 1.40
Mitochondrial K(ATP) channels in cell survival and death. J Mol Cell Cardiol (2005) 1.38
Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts. J Mol Cell Cardiol (2011) 1.34
Hypoxia-induced preconditioning in adult stimulated cardiomyocytes is mediated by the opening and trafficking of sarcolemmal KATP channels. FASEB J (2004) 1.30
Cardiac mitochondria and arrhythmias. Cardiovasc Res (2010) 1.29
Sildenafil and vardenafil but not nitroglycerin limit myocardial infarction through opening of mitochondrial K(ATP) channels when administered at reperfusion following ischemia in rabbits. J Mol Cell Cardiol (2006) 1.27
Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat. J Physiol (2005) 1.24
KATP channels and cardiovascular disease: suddenly a syndrome. Circ Res (2013) 1.23
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Mitochondrial approaches to protect against cardiac ischemia and reperfusion injury. Front Physiol (2011) 1.14
Sulfonylurea receptor-dependent and -independent pathways mediate vasodilation induced by ATP-sensitive K+ channel openers. Mol Pharmacol (2008) 1.13
Volatile anesthetic-induced cardiac preconditioning. J Anesth (2007) 1.12
Mitochondrial targets for volatile anesthetics against cardiac ischemia-reperfusion injury. Front Physiol (2014) 1.10
Mitochondrial potassium ATP channels and retinal ischemic preconditioning. Invest Ophthalmol Vis Sci (2006) 1.08
Platelet P2Y₁₂ blockers confer direct postconditioning-like protection in reperfused rabbit hearts. J Cardiovasc Pharmacol Ther (2012) 1.04
Pharmacological activation of plasma-membrane KATP channels reduces reoxygenation-induced Ca(2+) overload in cardiac myocytes via modulation of the diastolic membrane potential. Br J Pharmacol (2004) 1.04
Beta-oxidation of 5-hydroxydecanoate, a putative blocker of mitochondrial ATP-sensitive potassium channels. J Physiol (2003) 1.03
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Diazoxide maintenance of myocyte volume and contractility during stress: evidence for a non-sarcolemmal K(ATP) channel location. J Thorac Cardiovasc Surg (2010) 0.99
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5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids. J Physiol (2004) 0.98
Mitochondrial-mediated suppression of ROS production upon exposure of neurons to lethal stress: mitochondrial targeted preconditioning. Adv Drug Deliv Rev (2008) 0.97
Multiplicity of effectors of the cardioprotective agent, diazoxide. Pharmacol Ther (2013) 0.95
Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis. J Neuroinflammation (2011) 0.92
NRF2 and the Phase II Response in Acute Stress Resistance Induced by Dietary Restriction. J Clin Exp Pathol (2012) 0.92
Mitochondrial ATP-sensitive K+ channels, protectors of the heart. J Physiol (2010) 0.91
Defects in beta cell Ca²+ signalling, glucose metabolism and insulin secretion in a murine model of K(ATP) channel-induced neonatal diabetes mellitus. Diabetologia (2011) 0.91
KATP channel openers have opposite effects on mitochondrial respiration under different energetic conditions. J Cardiovasc Pharmacol (2008) 0.91
SUR2A C-terminal fragments reduce KATP currents and ischaemic tolerance of rat cardiac myocytes. J Physiol (2004) 0.90
The intracellular localization and function of the ATP-sensitive K+ channel subunit Kir6.1. J Membr Biol (2010) 0.89
Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression. J Physiol (2003) 0.89
Nitrite as a mediator of ischemic preconditioning and cytoprotection. Nitric Oxide (2011) 0.88
Role of adenosine A1 and A3 receptors in regulation of cardiomyocyte homeostasis after mitochondrial respiratory chain injury. Am J Physiol Heart Circ Physiol (2005) 0.87
Lack of manifestations of diazoxide/5-hydroxydecanoate-sensitive KATP channel in rat brain nonsynaptosomal mitochondria. J Physiol (2005) 0.87
Adenine nucleotide translocase mediates the K(ATP)-channel-openers-induced proton and potassium flux to the mitochondrial matrix. J Bioenerg Biomembr (2003) 0.86
Nox2 as a potential target of mitochondrial superoxide and its role in endothelial oxidative stress. Am J Physiol Heart Circ Physiol (2013) 0.86
Roles of KATP channels in delayed cardioprotection and intracellular Ca(2+) in the rat heart as revealed by kappa-opioid receptor stimulation with U50488H. Br J Pharmacol (2003) 0.86
Inhibition of Succinate Dehydrogenase by Diazoxide Is Independent of the ATP-Sensitive Potassium Channel Subunit Sulfonylurea Type 1 Receptor. J Am Coll Surg (2013) 0.86
Minoxidil opens mitochondrial K(ATP) channels and confers cardioprotection. Br J Pharmacol (2003) 0.86
Regulated production of free radicals by the mitochondrial electron transport chain: Cardiac ischemic preconditioning. Adv Drug Deliv Rev (2009) 0.85
Nicorandil attenuates the mitochondrial Ca2+ overload with accompanying depolarization of the mitochondrial membrane in the heart. Naunyn Schmiedebergs Arch Pharmacol (2003) 0.84
Study of the mechanism of action of diazoxide on rat heart mitochondria under calcium loading. Dokl Biochem Biophys (2006) 0.84
Cardioprotective mechanism of diazoxide involves the inhibition of succinate dehydrogenase. Ann Thorac Surg (2013) 0.84
Peroxynitrite decreases arrhythmias induced by ischaemia reperfusion in anaesthetized dogs, without involving mitochondrial KATP channels. Br J Pharmacol (2008) 0.84
Stimulation of neuronal KATP channels by cGMP-dependent protein kinase: involvement of ROS and 5-hydroxydecanoate-sensitive factors in signal transduction. Am J Physiol Cell Physiol (2010) 0.84
Complex I and ATP synthase mediate membrane depolarization and matrix acidification by isoflurane in mitochondria. Eur J Pharmacol (2012) 0.84
MitoK(ATP)-dependent changes in mitochondrial volume and in complex II activity during ischemic and pharmacological preconditioning of Langendorff-perfused rat heart. J Bioenerg Biomembr (2006) 0.84
Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation. Neurol Sci (2011) 0.83
KATP Channels in the Cardiovascular System. Physiol Rev (2016) 0.82
Targeted expression of Kir6.2 in mitochondria confers protection against hypoxic stress. J Physiol (2006) 0.82
Modulation of myocardial mitochondrial mechanisms during severe polymicrobial sepsis in the rat. PLoS One (2011) 0.81
Modulation of slow waves by hyperpolarization with potassium channel openers in antral smooth muscle of the guinea-pig stomach. J Physiol (2003) 0.81
Sevoflurane Preconditioning Reduces Intestinal Ischemia-Reperfusion Injury: Role of Protein Kinase C and Mitochondrial ATP-Sensitive Potassium Channel. PLoS One (2015) 0.80
Opening of the mitoKATP channel and decoupling of mitochondrial complex II and III contribute to the suppression of myocardial reperfusion hyperoxygenation. Mol Cell Biochem (2009) 0.80
Cardioprotection by preconditioning: K(ATP) channels, metabolism, or both? J Physiol (2002) 0.80
Factors mediating remote preconditioning of trauma in the rat heart: central role of the cytochrome p450 epoxygenase pathway in mediating infarct size reduction. J Cardiovasc Pharmacol Ther (2012) 0.79
Inhibition of oxygen consumption in skeletal muscle-derived mitochondria by pinacidil, diazoxide, and glibenclamide, but not by 5-hydroxydecanoate. J Bioenerg Biomembr (2010) 0.78
The cardioprotective effects of Na+/H+ exchange inhibition and mitochondrial KATP channel activation are additive in the isolated rat heart. Pflugers Arch (2003) 0.78
Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning. Anesthesiology (2016) 0.78
Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries. Am J Physiol Heart Circ Physiol (2015) 0.77
A new pROM king for the mitoK(ATP) dance: ROMK takes the lead. Circ Res (2012) 0.77
Effects of pinacidil and calcium on isolated rat heart mitochondria. Dokl Biochem Biophys (2012) 0.76
Modulation of the permeability transition pore by inhibition of the mitochondrial K(ATP) channel in liver vs. brain mitochondria. J Membr Biol (2007) 0.76
The role of mitochondrial K(ATP) channels in the antiarrhythmic effects of ischaemic preconditioning in dogs. Br J Pharmacol (2002) 0.76
Diazoxide Cardioprotection Is Independent of Adenosine Triphosphate-Sensitive Potassium Channel Kir6.1 Subunit in Response to Stress. J Am Coll Surg (2015) 0.75
Adenosine Triphosphate-Sensitive Potassium Channel Kir Subunits Implicated in Cardioprotection by Diazoxide. J Am Heart Assoc (2015) 0.75
Diazoxide protects against doxorubicin-induced cardiotoxicity in the rat. BMC Pharmacol Toxicol (2014) 0.75
Mitochondrial involvement in propofol-induced cardioprotection: An in vitro study in human myocardium. Exp Biol Med (Maywood) (2016) 0.75
Isosteviol Sensitizes sarcKATP Channels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes. Oxid Med Cell Longev (2016) 0.75
Cardiovascular KATP channels and advanced aging. Pathobiol Aging Age Relat Dis (2016) 0.75
High glucose stimulates cell proliferation and Collagen IV production in rat mesangial cells through inhibiting AMPK-KATP signaling. Int Urol Nephrol (2017) 0.75
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Chemical preconditioning with 3-nitropropionic acid in hearts: role of mitochondrial K(ATP) channel. Am J Physiol Heart Circ Physiol (2001) 1.21
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Contribution of inhibition of NADH-dehydrogenase to the cardiotoxic effects of halothane. J Mol Cell Cardiol (1974) 0.88
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Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem (2005) 1.64
Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome. Proc Natl Acad Sci U S A (2002) 1.58
Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2. J Physiol (2002) 1.56
The inhibition of the potassium channel TASK-1 in rat cardiac muscle by endothelin-1 is mediated by phospholipase C. Cardiovasc Res (2012) 1.51
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage. Arterioscler Thromb Vasc Biol (2009) 1.50
Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I. Mol Cell Biol (2009) 1.46
The iron-sulphur protein Ind1 is required for effective complex I assembly. EMBO J (2008) 1.42
Halothane, isoflurane and sevoflurane inhibit NADH:ubiquinone oxidoreductase (complex I) of cardiac mitochondria. J Physiol (2002) 1.41
Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex. Cell Metab (2012) 1.29
Interaction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3. J Physiol (2002) 1.24
Oligomeric and fibrillar species of beta-amyloid (A beta 42) both impair mitochondrial function in P301L tau transgenic mice. J Mol Med (Berl) (2008) 1.23
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Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins. J Physiol (2009) 1.18
Identification of the mitochondrial ND3 subunit as a structural component involved in the active/deactive enzyme transition of respiratory complex I. J Biol Chem (2008) 1.17
The proton pumping stoichiometry of purified mitochondrial complex I reconstituted into proteoliposomes. Biochim Biophys Acta (2006) 1.16
The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1. Traffic (2006) 1.15
Subunit mass fingerprinting of mitochondrial complex I. Biochim Biophys Acta (2008) 1.12
Subunit composition of mitochondrial complex I from the yeast Yarrowia lipolytica. Biochim Biophys Acta (2004) 1.12
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation. Antioxid Redox Signal (2012) 1.12
RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels. EMBO J (2010) 1.12
Exploring the ubiquinone binding cavity of respiratory complex I. J Biol Chem (2007) 1.10
HDQ (1-hydroxy-2-dodecyl-4(1H)quinolone), a high affinity inhibitor for mitochondrial alternative NADH dehydrogenase: evidence for a ping-pong mechanism. J Biol Chem (2004) 1.10
SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment. J Mol Med (Berl) (2006) 1.10
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APOOL is a cardiolipin-binding constituent of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria. PLoS One (2013) 1.05
A specific two-pore domain potassium channel blocker defines the structure of the TASK-1 open pore. J Biol Chem (2011) 1.04
Inhibitor binding in a class 2 dihydroorotate dehydrogenase causes variations in the membrane-associated N-terminal domain. Protein Sci (2004) 1.04
K+-independent actions of diazoxide question the role of inner membrane KATP channels in mitochondrial cytoprotective signaling. J Biol Chem (2006) 1.04
Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors. Hum Mol Genet (2013) 1.03
Beta-oxidation of 5-hydroxydecanoate, a putative blocker of mitochondrial ATP-sensitive potassium channels. J Physiol (2003) 1.03
A di-acidic sequence motif enhances the surface expression of the potassium channel TASK-3. Traffic (2007) 1.03
Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri. Aging Cell (2011) 1.03
Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2. EMBO J (2008) 1.02
Primary skin fibroblasts as a model of Parkinson's disease. Mol Neurobiol (2012) 1.01
Membrane proteins as 14-3-3 clients in functional regulation and intracellular transport. Physiology (Bethesda) (2011) 1.00
Functional implications from an unexpected position of the 49-kDa subunit of NADH:ubiquinone oxidoreductase. J Biol Chem (2003) 0.99
The Redox-Bohr group associated with iron-sulfur cluster N2 of complex I. J Biol Chem (2006) 0.99
Mitochondrial complex I is deficient in renal oncocytomas. Carcinogenesis (2003) 0.99
The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity. Proc Natl Acad Sci U S A (2014) 0.99
5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids. J Physiol (2004) 0.98
Direct localization of the 51 and 24 kDa subunits of mitochondrial complex I by three-dimensional difference imaging. J Struct Biol (2007) 0.98
Two-dimensional native electrophoretic analysis of respiratory supercomplexes from Yarrowia lipolytica. Proteomics (2009) 0.98
Yarrowia lipolytica, a yeast genetic system to study mitochondrial complex I. Biochim Biophys Acta (2002) 0.97
Exploring the inhibitor binding pocket of respiratory complex I. Biochim Biophys Acta (2008) 0.97
Impaired interaction between the slide helix and the C-terminus of Kir2.1: a novel mechanism of Andersen syndrome. Cardiovasc Res (2007) 0.96
Much more than a leak: structure and function of K₂p-channels. Pflugers Arch (2015) 0.96
Small single transmembrane domain (STMD) proteins organize the hydrophobic subunits of large membrane protein complexes. FEBS Lett (2010) 0.95
Effects of divalent cations and spermine on the K+ channel TASK-3 and on the outward current in thalamic neurons. J Physiol (2006) 0.95
The three families of respiratory NADH dehydrogenases. Results Probl Cell Differ (2008) 0.94
Quinone binding and reduction by respiratory complex I. Biochim Biophys Acta (2010) 0.93
Knock-out of the potassium channel TASK-1 leads to a prolonged QT interval and a disturbed QRS complex. Cell Physiol Biochem (2011) 0.93
Functional dissection of the proton pumping modules of mitochondrial complex I. PLoS Biol (2011) 0.93
Full recovery of the NADH:ubiquinone activity of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica by the addition of phospholipids. Biochim Biophys Acta (2002) 0.93
Proton pumping by complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica reconstituted into proteoliposomes. Biochim Biophys Acta (2005) 0.92
Functional significance of conserved histidines and arginines in the 49-kDa subunit of mitochondrial complex I. J Biol Chem (2004) 0.92
Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain complexes I and III. Biochim Biophys Acta (2009) 0.92
Subcomplexes of human ATP synthase mark mitochondrial biosynthesis disorders. Ann Neurol (2006) 0.91
Four novel splice variants of sulfonylurea receptor 1. Am J Physiol Cell Physiol (2002) 0.90
TASK-1 channels may modulate action potential duration of human atrial cardiomyocytes. Cell Physiol Biochem (2011) 0.90
Tight binding of NADPH to the 39-kDa subunit of complex I is not required for catalytic activity but stabilizes the multiprotein complex. Biochim Biophys Acta (2006) 0.89
Characterization of two different acyl carrier proteins in complex I from Yarrowia lipolytica. Biochim Biophys Acta (2009) 0.89
Functional sulfurtransferase is associated with mitochondrial complex I from Yarrowia lipolytica, but is not required for assembly of its iron-sulfur clusters. FEBS Lett (2005) 0.88
A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels. Pflugers Arch (2013) 0.87
Challenges in elucidating structure and mechanism of proton pumping NADH:ubiquinone oxidoreductase (complex I). J Bioenerg Biomembr (2008) 0.87
Relaxation filtered hyperfine (REFINE) spectroscopy: a novel tool for studying overlapping biological electron paramagnetic resonance signals applied to mitochondrial complex I. Biochemistry (2004) 0.87
Characterization of a subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I) lacking the flavoprotein part of the N-module. Biochim Biophys Acta (2007) 0.86
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Two different dihydroorotate dehydrogenases from yeast Saccharomyces kluyveri. FEBS Lett (2004) 0.85
Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans. FEBS J (2006) 0.85
The Toxoplasma gondii type-II NADH dehydrogenase TgNDH2-I is inhibited by 1-hydroxy-2-alkyl-4(1H)quinolones. Biochim Biophys Acta (2008) 0.85
Tracing the tail of ubiquinone in mitochondrial complex I. Biochim Biophys Acta (2012) 0.84
Tandem pore domain K(+)-channel TASK-3 (KCNK9) and idiopathic absence epilepsies. Am J Med Genet (2002) 0.84
Plant dihydroorotate dehydrogenase differs significantly in substrate specificity and inhibition from the animal enzymes. FEBS Lett (2002) 0.84
5-Hydroxydecanoate and coenzyme A are inhibitors of native sarcolemmal KATP channels in inside-out patches. Biochim Biophys Acta (2009) 0.84
Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4. J Biol Chem (2008) 0.84
Histidine 129 in the 75-kDa subunit of mitochondrial complex I from Yarrowia lipolytica is not a ligand for [Fe4S4] cluster N5 but is required for catalytic activity. J Biol Chem (2004) 0.84
Dihydroorotate dehydrogenase from Saccharomyces cerevisiae: spectroscopic investigations with the recombinant enzyme throw light on catalytic properties and metabolism of fumarate analogues. FEMS Yeast Res (2007) 0.84
Laser-induced liquid bead ion desorption-MS of protein complexes from blue-native gels, a sensitive top-down proteomic approach. Proteomics (2010) 0.84
The role of a conserved tyrosine in the 49-kDa subunit of complex I for ubiquinone binding and reduction. Biochim Biophys Acta (2010) 0.83
Application of the yeast Yarrowia lipolytica as a model to analyse human pathogenic mutations in mitochondrial complex I (NADH:ubiquinone oxidoreductase). Biochim Biophys Acta (2004) 0.83
Mechanism of thiazolidinedione-dependent cell death in Jurkat T cells. Mol Pharmacol (2007) 0.83