Published in Acta Neuropathol on June 26, 2002
Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations. Am J Hum Genet (2003) 2.58
CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations. Neurogenetics (2007) 2.11
A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells. Hum Mol Genet (2008) 2.02
Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis. Hum Mol Genet (2008) 1.95
Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations. Am J Pathol (2004) 1.30
Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke. Dis Model Mech (2008) 1.23
Neuronal expression of the Ccm2 gene in a new mouse model of cerebral cavernous malformations. Mamm Genome (2006) 1.23
STRIPAK complexes: structure, biological function, and involvement in human diseases. Int J Biochem Cell Biol (2013) 1.13
Cerebral cavernous malformations: somatic mutations in vascular endothelial cells. Neurosurgery (2009) 1.10
KRIT1 regulates the homeostasis of intracellular reactive oxygen species. PLoS One (2010) 1.05
Hox genes and their candidate downstream targets in the developing central nervous system. Cell Mol Neurobiol (2005) 0.94
Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype. FEBS J (2010) 0.92
Mutation prevalence of cerebral cavernous malformation genes in Spanish patients. PLoS One (2014) 0.83
Identification of two novel mutations and of a novel critical region in the KRIT1 gene. Neurogenetics (2006) 0.81
Genetics of cerebral cavernous malformations: current status and future prospects. J Neurosurg Sci (2015) 0.76
Introduction to cerebral cavernous malformation: a brief review. BMB Rep (2016) 0.76
CCM1 and the second life of proteins in adhesion complexes. Cell Adh Migr (2014) 0.75
High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes Cancer (2004) 11.79
Iatrogenic nerve injuries: prevalence, diagnosis and treatment. Dtsch Arztebl Int (2014) 2.57
SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway. EMBO J (2002) 2.26
Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution. BMC Evol Biol (2009) 1.40
Wide genome comparisons reveal the origins of the human X chromosome. Trends Genet (2004) 1.39
Complex patterns of copy number variation at sites of segmental duplications: an important category of structural variation in the human genome. Hum Genet (2006) 1.33
Reconstruction of a 450-My-old ancestral vertebrate protokaryotype. Trends Genet (2006) 1.29
Molecular characterization of the pericentric inversion that causes differences between chimpanzee chromosome 19 and human chromosome 17. Am J Hum Genet (2002) 1.19
Recent assembly of an imprinted domain from non-imprinted components. PLoS Genet (2006) 1.17
Breakpoint analysis of the pericentric inversion distinguishing human chromosome 4 from the homologous chromosome in the chimpanzee (Pan troglodytes). Hum Mutat (2005) 1.10
Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3. Gastroenterology (2002) 1.09
Spinal hematoma unrelated to previous surgery: analysis of 15 consecutive cases treated in a single institution within a 10-year period. Spine (Phila Pa 1976) (2004) 1.05
Anterior screw fixation in type II odontoid fractures: is there a difference in outcome between age groups? Neurosurgery (2003) 1.04
Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse. Genes Chromosomes Cancer (2003) 1.02
Accuracy of pedicle screw insertion in the cervical spine for internal fixation using frameless stereotactic guidance. J Neurosurg Spine (2008) 1.01
Identification of large-scale human-specific copy number differences by inter-species array comparative genomic hybridization. Hum Genet (2006) 0.99
Independent intrachromosomal recombination events underlie the pericentric inversions of chimpanzee and gorilla chromosomes homologous to human chromosome 16. Genome Res (2005) 0.98
Segmental duplication associated with the human-specific inversion of chromosome 18: a further example of the impact of segmental duplications on karyotype and genome evolution in primates. Hum Genet (2004) 0.98
Iatrogenic nerve injuries. Neurosurg Clin N Am (2009) 0.96
High-resolution ultrasonography in evaluating peripheral nerve entrapment and trauma. Neurosurg Focus (2009) 0.95
RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J. EMBO J (2010) 0.94
Neurological recovery and its influencing factors in thoracic and lumbar spine fractures after surgical decompression and stabilization. Neurosurg Rev (2004) 0.93
Polymorphic micro-inversions contribute to the genomic variability of humans and chimpanzees. Hum Genet (2005) 0.92
Enrichment of brain-related genes on the mammalian X chromosome is ancient and predates the divergence of synapsid and sauropsid lineages. Chromosome Res (2009) 0.90
Patient satisfaction and disability after brachial plexus surgery. Neurosurgery (2009) 0.90
Surgical treatment of traumatic peroneal nerve lesions. Neurosurgery (2008) 0.89
Surgical interventions for traumatic lesions of the brachial plexus: a retrospective study of 134 cases. J Neurosurg (2005) 0.88
Characterization of the human lineage-specific pericentric inversion that distinguishes human chromosome 1 from the homologous chromosomes of the great apes. Hum Genet (2006) 0.88
Success of simple sequestrectomy in lumbar spine surgery depends on the competence of the fibrous ring: a prospective controlled study of 168 patients. Spine (Phila Pa 1976) (2008) 0.87
Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5). Genes Chromosomes Cancer (2005) 0.85
An isochore transition zone in the NF1 gene region is a conserved landmark of chromosome structure and function. Genomics (2005) 0.85
Glioblastoma with adipocyte-like tumor cell differentiation--histological and molecular features of a rare differentiation pattern. Brain Pathol (2008) 0.85
Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis. Gene Expr Patterns (2003) 0.84
Avoiding iatrogenic nerve injury in endoscopic carpal tunnel release. Neurosurg Clin N Am (2009) 0.84
Molecular characterization of the pericentric inversion of chimpanzee chromosome 11 homologous to human chromosome 9. Genomics (2005) 0.84
Selective peripheral denervation for spasmodic torticollis: 13-year experience with 155 patients. J Neurosurg (2002) 0.84
Murine pancreatic tumor cell line TD2 bears the characteristic pattern of genetic changes with two independently amplified gene loci. Oncogene (2003) 0.83
Reconstruction of the ancestral ferungulate karyotype by electronic chromosome painting (E-painting). Chromosome Res (2007) 0.83
Molecular characterisation of t(17;22)(q11.2;q11.2) is not consistent with NF1 gene duplication. Hum Genet (2002) 0.83
A comparative expression analysis of four MRX genes regulating intracellular signalling via small GTPases. Eur J Hum Genet (2004) 0.82
Analysis of rare APC variants at the mRNA level: six pathogenic mutations and literature review. J Mol Diagn (2009) 0.82
Pattern of secondary genomic changes in pancreatic tumors of Tgf alpha/Trp53+/- transgenic mice. Genes Chromosomes Cancer (2003) 0.81
The influence of prophylactic vasoactive treatment on cochlear and facial nerve functions after vestibular schwannoma surgery: a prospective and open-label randomized pilot study. Neurosurgery (2007) 0.80
Molecular characterisation of the pericentric inversion that distinguishes human chromosome 5 from the homologous chimpanzee chromosome. Hum Genet (2005) 0.80
Proliferation and growth factor expression in abnormally enlarged placentas of mouse interspecific hybrids. Dev Dyn (2002) 0.80
The chimpanzee-specific pericentric inversions that distinguish humans and chimpanzees have identical breakpoints in Pan troglodytes and Pan paniscus. Genomics (2006) 0.79
Unique paleopathology in a pre-Columbian mummy remnant from Southern Peru--severe cervical rotation trauma with subluxation of the axis as cause of death. Acta Neurochir (Wien) (2010) 0.79
Role of intraoperative neurophysiology in primary surgery for obstetrical brachial plexus palsy (OBPP). Childs Nerv Syst (2006) 0.78
Treatment and outcome of aneurysmal subarachnoid haemorrhage in the elderly patient. Neuroradiology (2005) 0.78
Occurrence of an MLL/LAF4 fusion gene caused by the insertion ins(11;2)(q23;q11.2q11.2) in an infant with acute lymphoblastic leukemia. Genes Chromosomes Cancer (2003) 0.77
[Spontanious subarachnoidal hemorrhage: report on 67 surgicaly treated patients]. Med Arh (2006) 0.76
Cortex reorganization of Xenopus laevis eggs in strong static magnetic fields. Biomagn Res Technol (2005) 0.76
Frequency of cancer genes on the chicken z chromosome and its human homologues: implications for sex chromosome evolution. Comp Funct Genomics (2007) 0.75
Nerve sheath tumor surgery: case-guided discussion of ambiguous findings, appropriateness of removal, repeated surgery, and nerve repairs. Neurosurg Focus (2007) 0.75
[Intracranial aneurysms treated by means Guglielmi detachable coil]. Med Arh (2004) 0.75
Characterization of Pisrt1/Foxl2 in Ellobius lutescens and exclusion as sex-determining genes. Mamm Genome (2005) 0.75
Evaluation of traumatic cervical nerve root injuries by intraoperative evoked potentials. Neurosurgery (2002) 0.75