Published in EMBO J on November 23, 2010
Structure and function of the CSL-KyoT2 corepressor complex: a negative regulator of Notch signaling. Structure (2013) 1.51
A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes. Nucleic Acids Res (2016) 0.84
Gain of function notch phenotypes associated with ectopic expression of the Su(H) C-terminal domain illustrate separability of Notch and hairless-mediated activities. PLoS One (2013) 0.80
Immunohistochemical analysis of medullary breast carcinoma autoantigens in different histological types of breast carcinomas. Diagn Pathol (2012) 0.80
Negative control of CSL gene transcription by stress/DNA damage response and p53. Cell Cycle (2016) 0.79
Setting the Stage for Notch: The Drosophila Su(H)-Hairless Repressor Complex. PLoS Biol (2016) 0.76
The CSL proteins, versatile transcription factors and context dependent corepressors of the notch signaling pathway. Cell Div (2016) 0.75
Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes. J Biol Chem (2017) 0.75
PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation. Oncotarget (2016) 0.75
Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics. Oncogene (2016) 0.75
Early pancreatic islet fate and maturation is controlled through RBP-Jκ. Sci Rep (2016) 0.75
Monomeric Garnet, a far-red fluorescent protein for live-cell STED imaging. Sci Rep (2015) 0.75
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Analysis and prediction of leucine-rich nuclear export signals. Protein Eng Des Sel (2004) 5.15
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev (1998) 4.78
Notch signaling: the core pathway and its posttranslational regulation. Dev Cell (2009) 4.49
Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol Cell (2004) 3.85
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat Genet (2000) 3.82
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H). Curr Biol (1995) 3.46
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. Cell (2006) 3.42
Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature (1995) 3.39
The multifaceted role of Notch in cancer. Curr Opin Genet Dev (2006) 3.07
A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. EMBO J (1998) 3.04
Asymmetric centrosome inheritance maintains neural progenitors in the neocortex. Nature (2009) 3.03
p300 acts as a transcriptional coactivator for mammalian Notch-1. Mol Cell Biol (2001) 2.64
Notch and cancer: a double-edged sword. Cell Mol Life Sci (2007) 2.59
The Notch signaling pathway: transcriptional regulation at Notch target genes. Cell Mol Life Sci (2009) 2.51
The Xenopus homolog of Drosophila Suppressor of Hairless mediates Notch signaling during primary neurogenesis. Development (1997) 2.30
p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro. Mol Cell Biol (2002) 2.29
SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway. EMBO J (2002) 2.26
Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers. Genes Dev (2007) 2.19
Notch signaling in cancer. Curr Mol Med (2006) 2.14
Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Immunity (2003) 2.03
Turning it up a Notch: cross-talk between TGF beta and Notch signaling. Bioessays (2005) 1.95
Minimotif Miner: a tool for investigating protein function. Nat Methods (2006) 1.92
Off the beaten pathway: the complex cross talk between Notch and NF-kappaB. Lab Invest (2007) 1.80
mRuby, a bright monomeric red fluorescent protein for labeling of subcellular structures. PLoS One (2009) 1.79
Transcriptional repression by suppressor of hairless involves the binding of a hairless-dCtBP complex in Drosophila. Curr Biol (2001) 1.78
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes. Mol Cell Biol (2005) 1.72
Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing. Mol Cell (2009) 1.70
More complicated than it looks: assembly of Notch pathway transcription complexes. Oncogene (2008) 1.48
The Notch ligand, X-Delta-2, mediates segmentation of the paraxial mesoderm in Xenopus embryos. Development (1997) 1.45
Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex. Genes Dev (2010) 1.44
Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis. Development (2000) 1.43
Convergence of a head-field selector Otx2 and Notch signaling: a mechanism for lens specification. Development (2007) 1.33
Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex. Mol Cell Biol (2001) 1.31
Molecular targets of vertebrate segmentation: two mechanisms control segmental expression of Xenopus hairy2 during somite formation. Dev Cell (2001) 1.17
Conservation of Pax 6 function and upstream activation by Notch signaling in eye development of frogs and flies. Proc Natl Acad Sci U S A (2002) 1.15
Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms. Curr Opin Genet Dev (2008) 1.11
The role of Notch in lateral inhibition and cell fate specification. Mol Cell Neurosci (1995) 1.08
Loss of immunostaining of the RBP-J kappa transcription factor upon F9 cell differentiation induced by retinoic acid. J Biochem (1995) 1.03
Development and control of tissue separation at gastrulation in Xenopus. Dev Biol (2000) 1.02
Notch activates sonic hedgehog and both are involved in the specification of dorsal midline cell-fates in Xenopus. Development (2003) 0.96
ETO, but not leukemogenic fusion protein AML1/ETO, augments RBP-Jkappa/SHARP-mediated repression of notch target genes. Mol Cell Biol (2008) 0.93
Segmental chromosomal aberrations and centrosome amplifications: pathogenetic mechanisms in Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma? Leukemia (2003) 0.93
Notch regulates cell fate in the developing pronephros. Dev Biol (2000) 0.92
The role of GSK3beta in regulating neuronal differentiation in Xenopus laevis. Mol Cell Neurosci (1998) 0.89
Notch signaling modulates the nuclear localization of carboxy-terminal-phosphorylated smad2 and controls the competence of ectodermal cells for activin A. Mech Dev (2005) 0.83
Subdividing the embryo: a role for Notch signaling during germ layer patterning in Xenopus laevis. Dev Biol (2005) 0.82
Coordinating the timing of cardiac precursor development during gastrulation: a new role for Notch signaling. Dev Biol (2009) 0.78
EosFP, a fluorescent marker protein with UV-inducible green-to-red fluorescence conversion. Proc Natl Acad Sci U S A (2004) 6.71
T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance. Arterioscler Thromb Vasc Biol (2008) 5.44
NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest (2004) 5.06
Improving FRET dynamic range with bright green and red fluorescent proteins. Nat Methods (2012) 3.54
Diversity and evolution of coral fluorescent proteins. PLoS One (2008) 2.36
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Mol Cell (2004) 2.27
SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway. EMBO J (2002) 2.26
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b. Nature (2013) 2.19
Significantly improved precision of cell migration analysis in time-lapse video microscopy through use of a fully automated tracking system. BMC Cell Biol (2010) 2.04
Posttranslational modification of MDM2. Mol Cancer Res (2003) 1.97
Photodynamics of red fluorescent proteins studied by fluorescence correlation spectroscopy. Biophys J (2004) 1.92
Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells. Nat Cell Biol (2003) 1.84
IKK mediates ischemia-induced neuronal death. Nat Med (2005) 1.83
Photoconvertible fluorescent protein EosFP: biophysical properties and cell biology applications. Photochem Photobiol (2006) 1.79
mRuby, a bright monomeric red fluorescent protein for labeling of subcellular structures. PLoS One (2009) 1.79
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes. Mol Cell Biol (2005) 1.72
Structural basis for photo-induced protein cleavage and green-to-red conversion of fluorescent protein EosFP. Proc Natl Acad Sci U S A (2005) 1.70
Optimized and far-red-emitting variants of fluorescent protein eqFP611. Chem Biol (2008) 1.68
Transcriptional regulation of BMP4 synexpression in transgenic Xenopus. EMBO J (2004) 1.60
Fluorescent proteins for live cell imaging: opportunities, limitations, and challenges. IUBMB Life (2009) 1.60
From EosFP to mIrisFP: structure-based development of advanced photoactivatable marker proteins of the GFP-family. J Biophotonics (2011) 1.57
Association of the Mediator complex with enhancers of active genes. Proc Natl Acad Sci U S A (2003) 1.55
Contributions of host and symbiont pigments to the coloration of reef corals. FEBS J (2007) 1.55
Online image analysis software for photoactivation localization microscopy. Nat Methods (2009) 1.52
A green to red photoconvertible protein as an analyzing tool for early vertebrate development. Dev Dyn (2007) 1.48
Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex. Genes Dev (2010) 1.44
Sp1 is required for transforming growth factor-beta-induced mesenchymal transition and migration in pancreatic cancer cells. Cancer Res (2007) 1.41
Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics. Cancer Res (2010) 1.40
Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia. J Neurosci (2006) 1.40
Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation. Hepatology (2012) 1.40
Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution. BMC Evol Biol (2009) 1.40
Wide genome comparisons reveal the origins of the human X chromosome. Trends Genet (2004) 1.39
Characterization of sonic hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivo. FASEB J (2008) 1.37
Deficiency of innate and acquired immunity caused by an IKBKB mutation. N Engl J Med (2013) 1.37
Complex patterns of copy number variation at sites of segmental duplications: an important category of structural variation in the human genome. Hum Genet (2006) 1.33
It's cheap to be colorful. Anthozoans show a slow turnover of GFP-like proteins. FEBS J (2007) 1.30
The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220. Proc Natl Acad Sci U S A (2006) 1.30
Reconstruction of a 450-My-old ancestral vertebrate protokaryotype. Trends Genet (2006) 1.29
Sepsis induced changes of adipokines and cytokines - septic patients compared to morbidly obese patients. BMC Surg (2010) 1.28
Axial patterning in snakes and caecilians: evidence for an alternative interpretation of the Hox code. Dev Biol (2009) 1.25
The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization. J Exp Med (2004) 1.24
Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo. J Clin Invest (2007) 1.24
Identification of GFP-like proteins in nonbioluminescent, azooxanthellate anthozoa opens new perspectives for bioprospecting. Mar Biotechnol (NY) (2004) 1.21
De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health. Nat Commun (2013) 1.20
Molecular characterization of the pericentric inversion that causes differences between chimpanzee chromosome 19 and human chromosome 17. Am J Hum Genet (2002) 1.19
Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation. Mol Cell Biol (2003) 1.18
Recent assembly of an imprinted domain from non-imprinted components. PLoS Genet (2006) 1.17
Kinases as targets in the treatment of solid tumors. Cell Signal (2010) 1.17
Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response. J Cell Mol Med (2009) 1.17
A photoactivatable marker protein for pulse-chase imaging with superresolution. Nat Methods (2010) 1.17
Dietary polyphenol quercetin targets pancreatic cancer stem cells. Int J Oncol (2010) 1.14
The IKK2/NF-{kappa}B pathway suppresses MYC-induced lymphomagenesis. Blood (2009) 1.11
Breakpoint analysis of the pericentric inversion distinguishing human chromosome 4 from the homologous chromosome in the chimpanzee (Pan troglodytes). Hum Mutat (2005) 1.10
Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity, and nucleocytoplasmic shuttling. Mol Biol Cell (2005) 1.10
Structure, dynamics and optical properties of fluorescent proteins: perspectives for marker development. Chemphyschem (2009) 1.09
Protein kinase CK1delta phosphorylates key sites in the acidic domain of murine double-minute clone 2 protein (MDM2) that regulate p53 turnover. Biochemistry (2004) 1.09
Mutation and expression analysis of the KRIT1 gene associated with cerebral cavernous malformations (CCM1). Acta Neuropathol (2002) 1.09
NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes. Nucleic Acids Res (2011) 1.09
Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3. Gastroenterology (2002) 1.09
New views on cellular uptake and trafficking of manufactured nanoparticles. J R Soc Interface (2013) 1.09
IκB kinase/nuclear factor κB-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling. J Neurosci (2012) 1.08
Two-photon excitation and photoconversion of EosFP in dual-color 4Pi confocal microscopy. Biophys J (2007) 1.07
The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses. J Clin Invest (2009) 1.07
Protein kinases as targets for cancer treatment. Pharmacogenomics (2007) 1.06
The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells. Sci Signal (2014) 1.06
Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells. PLoS One (2011) 1.06
Fluorescent protein-mediated colour polymorphism in reef corals: multicopy genes extend the adaptation/acclimatization potential to variable light environments. Mol Ecol (2015) 1.05
Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help. Immunol Cell Biol (2011) 1.05
Keratin 8 phosphorylation regulates keratin reorganization and migration of epithelial tumor cells. J Cell Sci (2012) 1.04
Trans-cis isomerization is responsible for the red-shifted fluorescence in variants of the red fluorescent protein eqFP611. J Am Chem Soc (2008) 1.04
Stimulation of axon regeneration in the mature optic nerve by intravitreal application of the toll-like receptor 2 agonist Pam3Cys. Invest Ophthalmol Vis Sci (2009) 1.03
Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse. Genes Chromosomes Cancer (2003) 1.02
Sustained JNK activation in response to tumor necrosis factor is mediated by caspases in a cell type-specific manner. J Biol Chem (2006) 1.01
FoxN3 is required for craniofacial and eye development of Xenopus laevis. Dev Dyn (2007) 1.01
Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2. EMBO J (2007) 1.00
IL-20 receptor 2 signaling down-regulates antigen-specific T cell responses. J Immunol (2009) 1.00
Cooperative interaction of Xvent-2 and GATA-2 in the activation of the ventral homeobox gene Xvent-1B. J Biol Chem (2002) 1.00
Inhibition of casein kinase I delta alters mitotic spindle formation and induces apoptosis in trophoblast cells. Oncogene (2005) 0.99
Role of the second cysteine-rich domain and Pro275 in protein kinase D2 interaction with ADP-ribosylation factor 1, trans-Golgi network recruitment, and protein transport. Mol Biol Cell (2010) 0.99
Dual color photoactivation localization microscopy of cardiomyopathy-associated desmin mutants. J Biol Chem (2012) 0.99
Identification of large-scale human-specific copy number differences by inter-species array comparative genomic hybridization. Hum Genet (2006) 0.99
Independent intrachromosomal recombination events underlie the pericentric inversions of chimpanzee and gorilla chromosomes homologous to human chromosome 16. Genome Res (2005) 0.98
Cellular immune reaction in the pancreas is induced by constitutively active IkappaB kinase-2. Gut (2006) 0.98