Published in Dev Dyn on June 01, 2002
Placental contribution to the origins of sexual dimorphism in health and diseases: sex chromosomes and epigenetics. Biol Sex Differ (2013) 1.60
Cited1 is required in trophoblasts for placental development and for embryo growth and survival. Mol Cell Biol (2004) 1.03
Conservation of genomic imprinting at the XIST, IGF2, and GTL2 loci in the bovine. Mamm Genome (2004) 1.02
Sex-Specific Placental Responses in Fetal Development. Endocrinology (2015) 0.97
Mapping and identification of candidate loci responsible for Peromyscus hybrid overgrowth. Mamm Genome (2007) 0.91
Expression and function of the LIM homeobox containing genes Lhx3 and Lhx4 in the mouse placenta. Dev Dyn (2008) 0.75
Placental-specific IGF-II is a major modulator of placental and fetal growth. Nature (2002) 5.10
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet (2008) 3.89
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats. J Comp Neurol (2003) 3.08
BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. Cell Stem Cell (2011) 2.79
Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat Cell Biol (2008) 2.77
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol Cell Biol (2004) 2.65
Interactions between trophoblast cells and the maternal and fetal circulation in the mouse placenta. Dev Biol (2002) 2.63
Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis. Neuron (2010) 2.54
Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses. Neuron (2003) 2.42
Presenilins are essential for regulating neurotransmitter release. Nature (2009) 2.39
SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway. EMBO J (2002) 2.26
Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia. J Neurosci (2007) 2.24
Role of Runx genes in chondrocyte differentiation. Dev Biol (2002) 2.12
Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals. Chromosoma (2002) 2.03
Regulation of supply and demand for maternal nutrients in mammals by imprinted genes. J Physiol (2003) 2.01
Heterochromatin and tri-methylated lysine 20 of histone H4 in animals. J Cell Sci (2004) 1.98
Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets. Proc Natl Acad Sci U S A (2011) 1.95
Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease. J Clin Invest (2011) 1.79
The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development. Mol Cell Biol (2009) 1.78
Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage. J Neurosci (2005) 1.75
Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions. Hum Mol Genet (2003) 1.73
An allelic series for the leptin receptor gene generated by CRE and FLP recombinase. Mamm Genome (2004) 1.69
Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth. Proc Natl Acad Sci U S A (2011) 1.59
Transgenic rescue of insulin receptor-deficient mice. J Clin Invest (2004) 1.57
Mechanisms of disease: the developmental origins of disease and the role of the epigenotype. Nat Clin Pract Endocrinol Metab (2007) 1.54
The importance of cysteine cathepsin proteases for placental development. J Mol Med (Berl) (2006) 1.54
Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev (2006) 1.49
Phylogeography and postglacial expansion of Mus musculus domesticus inferred from mitochondrial DNA coalescent, from Iran to Europe. Mol Ecol (2007) 1.42
Unique receptor repertoire in mouse uterine NK cells. J Immunol (2008) 1.41
Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution. BMC Evol Biol (2009) 1.40
Wide genome comparisons reveal the origins of the human X chromosome. Trends Genet (2004) 1.39
Epigenetic dynamics of the Kcnq1 imprinted domain in the early embryo. Development (2006) 1.38
Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertility. Am J Physiol Endocrinol Metab (2005) 1.35
Complex patterns of copy number variation at sites of segmental duplications: an important category of structural variation in the human genome. Hum Genet (2006) 1.33
Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination. J Neurosci (2003) 1.31
The hormonal action of IGF1 in postnatal mouse growth. Proc Natl Acad Sci U S A (2008) 1.31
Reconstruction of a 450-My-old ancestral vertebrate protokaryotype. Trends Genet (2006) 1.29
HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions. J Cell Biol (2008) 1.27
Genetic differentiation of the house mouse around the Mediterranean basin: matrilineal footprints of early and late colonization. Proc Biol Sci (2010) 1.27
Wild-type huntingtin plays a role in brain development and neuronal survival. Mol Neurobiol (2003) 1.24
Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling. Dev Biol (2002) 1.24
Molecular characterization of the pericentric inversion that causes differences between chimpanzee chromosome 19 and human chromosome 17. Am J Hum Genet (2002) 1.19
Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice. Dis Model Mech (2013) 1.18
Recent assembly of an imprinted domain from non-imprinted components. PLoS Genet (2006) 1.17
Huntingtin inhibits caspase-3 activation. EMBO J (2006) 1.17
DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial. FASEB J (2012) 1.11
A transgenic mouse class-III beta tubulin reporter using yellow fluorescent protein. Genesis (2007) 1.11
Breakpoint analysis of the pericentric inversion distinguishing human chromosome 4 from the homologous chromosome in the chimpanzee (Pan troglodytes). Hum Mutat (2005) 1.10
Mutation and expression analysis of the KRIT1 gene associated with cerebral cavernous malformations (CCM1). Acta Neuropathol (2002) 1.09
Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3. Gastroenterology (2002) 1.09
The complex history of a gene proposed to participate in a sexual isolation mechanism in house mice. Mol Biol Evol (2002) 1.03
Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse. Genes Chromosomes Cancer (2003) 1.02
Expression of mouse Tbx22 supports its role in palatogenesis and glossogenesis. Dev Dyn (2003) 1.02
Species-wide distribution of highly polymorphic minisatellite markers suggests past and present genetic exchanges among house mouse subspecies. Genome Biol (2007) 1.00
Identification of large-scale human-specific copy number differences by inter-species array comparative genomic hybridization. Hum Genet (2006) 0.99
Genetics and neuropathology of Huntington's disease. Int Rev Neurobiol (2011) 0.99
Independent intrachromosomal recombination events underlie the pericentric inversions of chimpanzee and gorilla chromosomes homologous to human chromosome 16. Genome Res (2005) 0.98
Segmental duplication associated with the human-specific inversion of chromosome 18: a further example of the impact of segmental duplications on karyotype and genome evolution in primates. Hum Genet (2004) 0.98
Defining pathways that enforce cell lineage specification in early development and stem cells. Cell Cycle (2009) 0.97
Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice. Genes Dev (2011) 0.96
Fetal loss in homozygous mutant Norrie disease mice: a new role of Norrin in reproduction. Genesis (2005) 0.96
Widespread disruption of genomic imprinting in adult interspecies mouse (Mus) hybrids. Genesis (2005) 0.96
Choroideremia gene product affects trophoblast development and vascularization in mouse extra-embryonic tissues. Dev Biol (2004) 0.96
DNA methylation profiles define stem cell identity and reveal a tight embryonic-extraembryonic lineage boundary. Stem Cells (2012) 0.96
Long-term balancing selection at the west nile virus resistance gene, Oas1b, maintains transspecific polymorphisms in the house mouse. Mol Biol Evol (2008) 0.95
Deletion of exon 20 of the Familial Dysautonomia gene Ikbkap in mice causes developmental delay, cardiovascular defects, and early embryonic lethality. PLoS One (2011) 0.95
Loss-of-imprinting of Peg1 in mouse interspecies hybrids is correlated with altered growth. Genesis (2004) 0.95
Developmental adaptations to increased fetal nutrient demand in mouse genetic models of Igf2-mediated overgrowth. FASEB J (2011) 0.95
Placental adaptations to the maternal-fetal environment: implications for fetal growth and developmental programming. Reprod Biomed Online (2012) 0.95
Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate. Dev Biol (2009) 0.95
RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J. EMBO J (2010) 0.94
A placenta for life. Reprod Biomed Online (2012) 0.93
IKAP expression levels modulate disease severity in a mouse model of familial dysautonomia. Hum Mol Genet (2012) 0.93
Raised late pregnancy glucose concentrations in mice carrying pups with targeted disruption of H19delta13. Diabetes (2009) 0.92
Polymorphic micro-inversions contribute to the genomic variability of humans and chimpanzees. Hum Genet (2005) 0.92
Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts. BMC Neurosci (2008) 0.92
Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages. Hum Mol Genet (2008) 0.92
PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis. Sci Signal (2010) 0.92
Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes. Cell Mol Life Sci (2013) 0.91
Influence of murine maternal diabetes on placental morphology, gene expression, and function. Arch Physiol Biochem (2008) 0.90
Enrichment of brain-related genes on the mammalian X chromosome is ancient and predates the divergence of synapsid and sauropsid lineages. Chromosome Res (2009) 0.90
Overexpression of RPGR leads to male infertility in mice due to defects in flagellar assembly. Biol Reprod (2008) 0.89
How genome-wide approaches can be used to unravel the remaining secrets of the imprintome. Brief Funct Genomics (2010) 0.89
Functional consequences of naturally occurring DRY motif variants in the mammalian chemoattractant receptor GPR33. Genomics (2006) 0.88
Characterization of the human lineage-specific pericentric inversion that distinguishes human chromosome 1 from the homologous chromosomes of the great apes. Hum Genet (2006) 0.88
Cathepsin proteases have distinct roles in trophoblast function and vascular remodelling. Development (2008) 0.87
Different molecular mechanisms underlie placental overgrowth phenotypes caused by interspecies hybridization, cloning, and Esx1 mutation. Dev Dyn (2004) 0.86
Cutting edge: Conditional MHC class II expression reveals a limited role for B cell antigen presentation in primary and secondary CD4 T cell responses. J Immunol (2013) 0.86
Down-regulation of Cdx2 in colorectal carcinoma cells by the Raf-MEK-ERK 1/2 pathway. Cell Signal (2009) 0.86
An isochore transition zone in the NF1 gene region is a conserved landmark of chromosome structure and function. Genomics (2005) 0.85
Lgals6, a 2-million-year-old gene in mice: a case of positive Darwinian selection and presence/absence polymorphism. Genetics (2008) 0.85
Placental programming of anxiety in adulthood revealed by Igf2-null models. Nat Commun (2013) 0.85
Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis. Gene Expr Patterns (2003) 0.84
Molecular characterization of the pericentric inversion of chimpanzee chromosome 11 homologous to human chromosome 9. Genomics (2005) 0.84
Molecular characterisation of t(17;22)(q11.2;q11.2) is not consistent with NF1 gene duplication. Hum Genet (2002) 0.83