Published in Nitric Oxide on August 01, 2002
Nitric oxide and redox mechanisms in the immune response. J Leukoc Biol (2011) 1.97
COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model. Proc Natl Acad Sci U S A (2006) 1.42
Camel milk peptide improves wound healing in diabetic rats by orchestrating the redox status and immune response. Lipids Health Dis (2015) 1.40
Reduced foreign body response at nitric oxide-releasing subcutaneous implants. Biomaterials (2007) 1.33
Analytical chemistry of nitric oxide. Annu Rev Anal Chem (Palo Alto Calif) (2009) 1.32
Nitric oxide is a key component in inflammation-accelerated tumorigenesis. Cancer Res (2008) 1.19
Molecular mechanisms for discrete nitric oxide levels in cancer. Nitric Oxide (2008) 1.14
Biocompatible materials for continuous glucose monitoring devices. Chem Rev (2013) 1.10
Oxidative and nitrosative stress and fibrogenic response. Clin Liver Dis (2008) 1.09
Inflammatory levels of nitric oxide inhibit airway epithelial cell migration by inhibition of the kinase ERK1/2 and activation of hypoxia-inducible factor-1 alpha. J Biol Chem (2008) 1.08
Whey protein enhances normal inflammatory responses during cutaneous wound healing in diabetic rats. Lipids Health Dis (2011) 1.06
Matrix metalloproteinase 13 mediates nitric oxide activation of endothelial cell migration. Proc Natl Acad Sci U S A (2005) 1.02
Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells. Br J Pharmacol (2009) 0.97
Non-cytotoxic, in situ gelable hydrogels composed of N-carboxyethyl chitosan and oxidized dextran. Biomaterials (2008) 0.97
Nitric oxide accelerates the recovery from burn wounds. World J Surg (2007) 0.96
Polymer-Based Nitric Oxide Therapies: Recent Insights for Biomedical Applications. Adv Funct Mater (2012) 0.94
Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2. Proc Natl Acad Sci U S A (2011) 0.94
Decreasing bacterial colonization of external fixation pins through nitric oxide release coatings. J Orthop Trauma (2011) 0.93
Diabetes-impaired wound healing is improved by matrix therapy with heparan sulfate glycosaminoglycan mimetic OTR4120 in rats. Diabetes (2012) 0.92
Limiting prolonged inflammation during proliferation and remodeling phases of wound healing in streptozotocin-induced diabetic rats supplemented with camel undenatured whey protein. BMC Immunol (2013) 0.91
Oral administration of skin gelatin isolated from Chum salmon (Oncorhynchus keta) enhances wound healing in diabetic rats. Mar Drugs (2011) 0.90
Neutrophil depletion in the early inflammatory phase delayed cutaneous wound healing in older rats: improvements due to the use of un-denatured camel whey protein. Diagn Pathol (2014) 0.88
The effect of nitric oxide surface flux on the foreign body response to subcutaneous implants. Biomaterials (2012) 0.87
Nitric oxide nanoparticle technology: a novel antimicrobial agent in the context of current treatment of skin and soft tissue infection. J Clin Aesthet Dermatol (2010) 0.86
Substance P enhances wound closure in nitric oxide synthase knockout mice. J Surg Res (2008) 0.86
Increased in vivo glucose recovery via nitric oxide release. Anal Chem (2011) 0.85
Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase. Toxicology (2006) 0.84
Cystathionine γ-lyase regulates arteriogenesis through NO-dependent monocyte recruitment. Cardiovasc Res (2015) 0.83
Immunotoxicity of zinc oxide nanoparticles with different size and electrostatic charge. Int J Nanomedicine (2014) 0.83
Activation of latent transforming growth factor-beta1 by nitric oxide in macrophages: role of soluble guanylate cyclase and MAP kinases. Wound Repair Regen (2009) 0.83
Single-dose pharmacokinetics of different oral sodium nitrite formulations in diabetes patients. Diabetes Technol Ther (2012) 0.82
Signaling and stress: The redox landscape in NOS2 biology. Free Radic Biol Med (2015) 0.82
Honey: a potential therapeutic agent for managing diabetic wounds. Evid Based Complement Alternat Med (2014) 0.81
NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay. Cancer Res (2015) 0.81
Impaired wound repair in adult endoglin heterozygous mice associated with lower NO bioavailability. J Invest Dermatol (2013) 0.79
Efficacy of a children's procedural preparation and distraction device on healing in acute burn wound care procedures: study protocol for a randomized controlled trial. Trials (2012) 0.79
Computational Modeling of Inflammation and Wound Healing. Adv Wound Care (New Rochelle) (2013) 0.79
Factors That Impair Wound Healing. J Am Coll Clin Wound Spec (2014) 0.79
Enhancement of Wound Healing by Non-Thermal N2/Ar Micro-Plasma Exposure in Mice with Fractional-CO2-Laser-Induced Wounds. PLoS One (2016) 0.78
In vivo analytical performance of nitric oxide-releasing glucose biosensors. Anal Chem (2014) 0.78
Measurement of NF-kappaB in normal and reconstructed human skin in vitro. J Mater Sci Mater Med (2004) 0.78
Nanotechnology-Driven Therapeutic Interventions in Wound Healing: Potential Uses and Applications. ACS Cent Sci (2017) 0.77
Association between red blood cell storage duration and clinical outcome in patients undergoing off-pump coronary artery bypass surgery: a retrospective study. BMC Anesthesiol (2014) 0.77
Inducible nitric oxide synthase inhibition influenced granuloma formation with suppressed collagen expression in myositis caused by Toxocara canis in mice. Parasitol Res (2007) 0.77
Topical sodium nitrite for chronic leg ulcers in patients with sickle cell anaemia: a phase 1 dose-finding safety and tolerability trial. Lancet Haematol (2014) 0.77
Nitric oxide promotes epidermal stem cell migration via cGMP-Rho GTPase signalling. Sci Rep (2016) 0.77
In vivo modulation of iNOS pathway in hepatocellular carcinoma by Nigella sativa. Environ Health Prev Med (2013) 0.76
Wound-healing potential of the fruit extract of Phaleria macrocarpa. Bosn J Basic Med Sci (2015) 0.76
Assessment of the effect of diode laser therapy on incisional wound healing and expression of iNOS and eNOS on rat oral tissue. Dent Res J (Isfahan) (2013) 0.76
Pharmacologic overview of systemic chlorogenic acid therapy on experimental wound healing. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.76
Promoting Wound Healing Using Low Molecular Weight Fucoidan in a Full-Thickness Dermal Excision Rat Model. Mar Drugs (2017) 0.75
Growth hormone abolishes the negative effects of everolimus on intestinal wound healing. World J Gastroenterol (2016) 0.75
In vitro and in vivo suppression of cellular activity by guanidinoethyl disulfide released from hydrogel microspheres composed of partially oxidized hyaluronan and gelatin. Biomaterials (2008) 0.75
Immunotoxicity of silicon dioxide nanoparticles with different sizes and electrostatic charge. Int J Nanomedicine (2014) 0.75
Anti-Inflammatory Properties of Flavone di-C-Glycosides as Active Principles of Camellia Mistletoe, Korthalsella japonica. Biomol Ther (Seoul) (2016) 0.75
Functionalized Mesoporous Silica via an Aminosilane Surfactant Ion Exchange Reaction: Controlled Scaffold Design and Nitric Oxide Release. ACS Appl Mater Interfaces (2016) 0.75
Nitric oxide synthase gene transfer overcomes the inhibition of wound healing by sulfur mustard in a human keratinocyte in vitro model. ISRN Toxicol (2012) 0.75
In situ eNOS/NO up-regulation-a simple and effective therapeutic strategy for diabetic skin ulcer. Sci Rep (2016) 0.75
The effect of nitric oxide releasing cream on healing pressure ulcers. Iran J Nurs Midwifery Res (2016) 0.75
Effect of Nitric Oxide on Human Corneal Epithelial Cell Viability and Corneal Wound Healing. Sci Rep (2017) 0.75
Effects of epidermal growth factor on lipid peroxidation and nitric oxide levels in oral mucosal ulcer healing: a time-course study. Surg Today (2007) 0.75
Low temperature plasma promoting fibroblast proliferation by activating the NF-κB pathway and increasing cyclinD1 expression. Sci Rep (2017) 0.75
Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A (2013) 16.74
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med (2005) 6.86
A genomic storm in critically injured humans. J Exp Med (2011) 6.67
HMGB1: endogenous danger signaling. Mol Med (2008) 4.02
HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling. J Exp Med (2007) 3.72
Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells. J Immunol (2005) 2.78
Emerging paradigm: toll-like receptor 4-sentinel for the detection of tissue damage. Shock (2006) 2.61
Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome. J Trauma (2009) 2.49
Oral hydrogen water prevents chronic allograft nephropathy in rats. Kidney Int (2009) 2.35
Debunking the survival bias myth: characterization of mortality during the initial 24 hours for patients requiring massive transfusion. J Trauma Acute Care Surg (2012) 2.32
Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock. Mol Med (2006) 2.27
An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma (2008) 2.15
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Nat Med (2003) 2.15
Systemic inflammation and remote organ injury following trauma require HMGB1. Am J Physiol Regul Integr Comp Physiol (2007) 2.12
Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures. Ann Surg (2012) 2.07
Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier. J Immunol (2006) 2.06
Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling. J Immunol (2007) 2.02
Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism. Hepatology (2009) 1.98
High-mobility group box 1 is essential for mitochondrial quality control. Cell Metab (2011) 1.89
Role of toll-like receptors in changes in gene expression and NF-kappa B activation in mouse hepatocytes stimulated with lipopolysaccharide. Infect Immun (2002) 1.85
The acute inflammatory response in diverse shock states. Shock (2005) 1.83
Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both. J Heart Lung Transplant (2009) 1.78
In silico design of clinical trials: a method coming of age. Crit Care Med (2004) 1.78
Agent-based models in translational systems biology. Wiley Interdiscip Rev Syst Biol Med (2010) 1.70
A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine. Crit Care Med (2012) 1.69
A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation. J Theor Biol (2006) 1.68
A reduced mathematical model of the acute inflammatory response II. Capturing scenarios of repeated endotoxin administration. J Theor Biol (2006) 1.65
Early events in the recognition of danger signals after tissue injury. J Leukoc Biol (2007) 1.65
Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix. J Trauma Acute Care Surg (2012) 1.60
Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species. FASEB J (2007) 1.60
The dynamics of acute inflammation. J Theor Biol (2004) 1.60
Pivotal advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through distinct but overlapping mechanisms. J Leukoc Biol (2010) 1.59
Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice. Gastroenterology (2012) 1.59
Resetting the transcription factor network reverses terminal chronic hepatic failure. J Clin Invest (2015) 1.58
Prehospital Hypotension Is Associated With Altered Inflammation Dynamics and Worse Outcomes Following Blunt Trauma in Humans. Crit Care Med (2015) 1.58
Toll-like receptor-4 signaling mediates hepatic injury and systemic inflammation in hemorrhagic shock. J Am Coll Surg (2006) 1.57
Inducible protein-10, a potential driver of neurally controlled interleukin-10 and morbidity in human blunt trauma. Crit Care Med (2014) 1.57
Physiologic responses to severe hemorrhagic shock and the genesis of cardiovascular collapse: can irreversibility be anticipated? J Surg Res (2012) 1.53
Male gender is associated with excessive IL-6 expression following severe injury. J Trauma (2008) 1.51
Beta2-integrin-induced p38 MAPK activation is a key mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes. J Biol Chem (2008) 1.49
Thioredoxin catalyzes the denitrosation of low-molecular mass and protein S-nitrosothiols. Biochemistry (2007) 1.49
Over reliance on computed tomography imaging in patients with severe abdominal injury: is the delay worth the risk? J Trauma (2011) 1.45
Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols. J Am Chem Soc (2005) 1.45
Systolic blood pressure criteria in the National Trauma Triage Protocol for geriatric trauma: 110 is the new 90. J Trauma Acute Care Surg (2015) 1.42
Intra-abdominal activation of a local inflammatory response within the human muscularis externa during laparotomy. Ann Surg (2003) 1.42
Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement. Biochem Biophys Res Commun (2012) 1.42
Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury. J Immunol (2006) 1.42
Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study. Int Urol Nephrol (2009) 1.41
Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase. J Exp Med (2005) 1.40
Systemic inflammation and remote organ damage following bilateral femur fracture requires Toll-like receptor 4. Am J Physiol Regul Integr Comp Physiol (2006) 1.40
Calcium/calmodulin-dependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages. J Immunol (2008) 1.39
Agent-based model of inflammation and wound healing: insights into diabetic foot ulcer pathology and the role of transforming growth factor-beta1. Wound Repair Regen (2007) 1.39
Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1. J Exp Med (2003) 1.39
A patient-specific in silico model of inflammation and healing tested in acute vocal fold injury. PLoS One (2008) 1.38
Hemorrhagic shock augments lung endothelial cell activation: role of temporal alterations of TLR4 and TLR2. Am J Physiol Regul Integr Comp Physiol (2009) 1.36
Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Am J Transplant (2005) 1.36
Goal-directed resuscitation in the prehospital setting: a propensity-adjusted analysis. J Trauma Acute Care Surg (2013) 1.36
Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients. J Immunol (2009) 1.35
Benzyl alcohol attenuates acetaminophen-induced acute liver injury in a Toll-like receptor-4-dependent pattern in mice. Hepatology (2014) 1.35
Early airway pressure release ventilation prevents ARDS-a novel preventive approach to lung injury. Shock (2013) 1.35
Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A (2010) 1.33
Induced nitric oxide promotes intestinal inflammation following hemorrhagic shock. Am J Physiol Gastrointest Liver Physiol (2004) 1.33
Role of heme oxygenase 1 in TNF/TNF receptor-mediated apoptosis after hepatic ischemia/reperfusion in rats. Shock (2013) 1.32
Systemic inflammation and end organ damage following trauma involves functional TLR4 signaling in both bone marrow-derived cells and parenchymal cells. J Leukoc Biol (2007) 1.31
Role of nitric oxide in liver injury. Curr Mol Med (2003) 1.30
Tissue hypoxia activates JNK in the liver during hemorrhagic shock. Shock (2004) 1.30
Therapeutic antioxidant medical gas. J Clin Biochem Nutr (2008) 1.29
Sepsis: Something old, something new, and a systems view. J Crit Care (2011) 1.29
Blood soluble drag-reducing polymers prevent lethality from hemorrhagic shock in acute animal experiments. Biorheology (2004) 1.29
Selective jejunal manipulation causes postoperative pan-enteric inflammation and dysmotility. Gastroenterology (2004) 1.28
Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury. J Leukoc Biol (2006) 1.27
Nitric oxide facilitates cardiomyogenesis in mouse embryonic stem cells. Proc Natl Acad Sci U S A (2004) 1.25
Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells. J Immunol (2011) 1.25
In silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice. Mol Med (2006) 1.25
A dynamic view of trauma/hemorrhage-induced inflammation in mice: principal drivers and networks. PLoS One (2011) 1.24
Lipopolysaccharide clearance, bacterial clearance, and systemic inflammatory responses are regulated by cell type-specific functions of TLR4 during sepsis. J Immunol (2013) 1.23
Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14. Mol Med (2013) 1.23
Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS. J Cereb Blood Flow Metab (2005) 1.23
A Janus tale of two active high mobility group box 1 (HMGB1) redox states. Mol Med (2012) 1.21
Cellular-specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury in mice. Hepatology (2013) 1.21
Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion. Transplantation (2007) 1.21
Augmenting autophagy to treat acute kidney injury during endotoxemia in mice. PLoS One (2013) 1.21
Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies. Curr Mol Med (2004) 1.21