Published in J Biol Chem on August 22, 2002
Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier. J Biol Chem (2009) 1.82
Novel fluorescent glycan microarray strategy reveals ligands for galectins. Chem Biol (2009) 1.66
Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on alpha3beta1 integrin. J Cell Sci (2009) 1.26
Galectin-7 in the control of epidermal homeostasis after injury. Mol Biol Cell (2008) 1.11
Bisecting GlcNAc residues on laminin-332 down-regulate galectin-3-dependent keratinocyte motility. J Biol Chem (2009) 0.99
Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration. J Invest Dermatol (2012) 0.98
Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer. Oncotarget (2013) 0.98
Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells. Am J Physiol Renal Physiol (2011) 0.97
Soluble galectin-3 is a strong, colonic epithelial-cell-derived, lamina propria fibroblast-stimulating factor. Gut (2006) 0.95
Mitochondrial proteomic approach reveals galectin-7 as a novel BCL-2 binding protein in human cells. Mol Biol Cell (2011) 0.95
Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation. J Invest Dermatol (2008) 0.93
Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration. J Biol Chem (2012) 0.89
The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. Glycobiology (2008) 0.88
Analysis of differential expression of glycosyltransferases in healing corneas by glycogene microarrays. Glycobiology (2009) 0.88
Molecular basis for MMP9 induction and disruption of epithelial cell-cell contacts by galectin-3. J Cell Sci (2014) 0.88
Matrilysin-1 (MMP7) cleaves galectin-3 and inhibits wound healing in intestinal epithelial cells. Inflamm Bowel Dis (2010) 0.87
Glycobiology of the ocular surface: mucins and lectins. Jpn J Ophthalmol (2013) 0.87
Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Brain Behav (2012) 0.86
Glycoprotein 340 in normal human ocular surface tissues and tear film. Infect Immun (2006) 0.85
Modulation of ocular surface glycocalyx barrier function by a galectin-3 N-terminal deletion mutant and membrane-anchored synthetic glycopolymers. PLoS One (2013) 0.85
A perspective on new immune adjuvant principles: Reprogramming inflammatory states to permit clearance of cancer cells and other age-associated cellular pathologies. Oncoimmunology (2012) 0.84
Dry eye and designer ophthalmics. Optom Vis Sci (2008) 0.84
Structural features for α-galactomannan binding to galectin-1. Glycobiology (2011) 0.83
Binding of transmembrane mucins to galectin-3 limits herpesvirus 1 infection of human corneal keratinocytes. J Virol (2013) 0.83
The ocular surface epithelial barrier and other mechanisms of mucosal protection: from allergy to infectious diseases. Curr Opin Allergy Clin Immunol (2013) 0.83
Ozone-induced injury and oxidative stress in bronchiolar epithelium are associated with altered pulmonary mechanics. Toxicol Sci (2013) 0.82
Detection of galectin-3 interaction with commensal bacteria. Appl Environ Microbiol (2013) 0.82
NOD-like receptors in intestinal homeostasis and epithelial tissue repair. Int J Mol Sci (2014) 0.82
Increased cell proliferation and differential protein expression induced by low-level Er:YAG laser irradiation in human gingival fibroblasts: proteomic analysis. Lasers Med Sci (2014) 0.82
Role of galectins in re-epithelialization of wounds. Ann Transl Med (2014) 0.81
Detection of differentially expressed wound-healing-related glycogenes in galectin-3-deficient mice. Invest Ophthalmol Vis Sci (2009) 0.80
The role of galectin-3 and galectin-3-binding protein in venous thrombosis. Blood (2014) 0.80
Galectins in epithelial functions. Tissue Barriers (2014) 0.80
Open Wound Healing In Vivo: Monitoring Binding and Presence of Adhesion/Growth-Regulatory Galectins in Rat Skin during the Course of Complete Re-Epithelialization. Acta Histochem Cytochem (2011) 0.79
Crystallization and preliminary X-ray diffraction analysis of mouse galectin-4 N-terminal carbohydrate recognition domain in complex with lactose. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.79
Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sulfur mustard. Exp Mol Pathol (2014) 0.78
The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase. PLoS One (2011) 0.78
Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair. PLoS One (2015) 0.77
Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor. FEBS J (2011) 0.77
Galectin-1-specific inhibitors as a new class of compounds to treat HIV-1 infection. Antimicrob Agents Chemother (2011) 0.77
Galectin-3 as a Potential Target to Prevent Cancer Metastasis. Clin Med Insights Oncol (2015) 0.77
Fingerprinting of galectins in normal, P. aeruginosa-infected, and chemically burned mouse corneas. Invest Ophthalmol Vis Sci (2015) 0.76
Galectin-3 as a regulator of the epithelial junction: Implications to wound repair and cancer. Tissue Barriers (2015) 0.76
Galectin-3: a potential target for cancer prevention. Trends Carbohydr Res (2011) 0.76
Lectins, Interconnecting Proteins with Biotechnological/Pharmacological and Therapeutic Applications. Evid Based Complement Alternat Med (2017) 0.75
A Mutation in the Carbohydrate Recognition Domain Drives a Phenotypic Switch in the Role of Galectin-7 in Prostate Cancer. PLoS One (2015) 0.75
Tissue injury and repair following cutaneous exposure of mice to sulfur mustard. Ann N Y Acad Sci (2016) 0.75
Galectin-3 enhances extracellular matrix associations and wound healing in monkey corneal epithelium. Exp Eye Res (2015) 0.75
Analysis of the effects of preservative-free tafluprost on the tear proteome. Am J Transl Res (2016) 0.75
Invisible Shield: Review of the Corneal Epithelium as a Barrier to UV Radiation, Pathogens, and Other Environmental Stimuli. J Ophthalmic Vis Res (2017) 0.75
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. Am J Pathol (2008) 2.83
Galectins: structure, function and therapeutic potential. Expert Rev Mol Med (2008) 2.61
Critical role of galectin-3 in phagocytosis by macrophages. J Clin Invest (2003) 2.18
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death. J Immunol (2006) 2.14
Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI. Proc Natl Acad Sci U S A (2003) 1.94
Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier. J Biol Chem (2009) 1.82
Galectin-3 induces death of Candida species expressing specific beta-1,2-linked mannans. J Immunol (2006) 1.61
Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. J Invest Dermatol (2008) 1.42
Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med (2010) 1.41
Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis. Hepatology (2013) 1.33
Detection of differentially expressed glycogenes in trabecular meshwork of eyes with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2006) 1.30
Galectin-3 is a negative regulator of lipopolysaccharide-mediated inflammation. J Immunol (2008) 1.29
Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.28
Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on alpha3beta1 integrin. J Cell Sci (2009) 1.26
Cell mechanics using atomic force microscopy-based single-cell compression. Langmuir (2006) 1.26
Cloning and characterization of a novel mannose-binding protein of Acanthamoeba. J Biol Chem (2004) 1.25
Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release. J Biol Chem (2001) 1.25
Galectin-3 mediates IL-4-induced survival and differentiation of B cells: functional cross-talk and implications during Trypanosoma cruzi infection. J Immunol (2004) 1.24
Role of galectin-3 in human pulmonary fibrosis. Allergol Int (2007) 1.24
Galectin-3 functions as an adhesion molecule to support eosinophil rolling and adhesion under conditions of flow. J Immunol (2007) 1.23
Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol (2004) 1.22
LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition. J Immunol (2004) 1.22
Galectin 3 and its binding protein in rheumatoid arthritis. Arthritis Rheum (2003) 1.20
Regulation of cellular homeostasis by galectins. Glycoconj J (2004) 1.20
Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner. J Biol Chem (2008) 1.16
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Proc Natl Acad Sci U S A (2009) 1.16
Toxoplasma gondii infection reveals a novel regulatory role for galectin-3 in the interface of innate and adaptive immunity. Am J Pathol (2006) 1.14
Galectin-3 regulates T-cell functions. Immunol Rev (2009) 1.14
Detection of differentially expressed genes in healing mouse corneas, using cDNA microarrays. Invest Ophthalmol Vis Sci (2002) 1.13
Galectin-3 protein modulates cell surface expression and activation of vascular endothelial growth factor receptor 2 in human endothelial cells. J Biol Chem (2011) 1.13
Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells. J Invest Dermatol (2008) 1.13
IgE-dependent mast cell activation potentiates airway responses in murine asthma models. J Immunol (2002) 1.13
Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension. Am J Pathol (2007) 1.12
Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression. J Immunol (2006) 1.12
The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling. J Biol Chem (2009) 1.12
Galectins in apoptosis. Methods Enzymol (2006) 1.12
The immunological potential of galectin-1 and -3. Autoimmun Rev (2008) 1.11
Galectin-3 preserves renal tubules and modulates extracellular matrix remodeling in progressive fibrosis. Am J Physiol Renal Physiol (2010) 1.10
Aberrant promoter methylation of SPARC in ovarian cancer. Neoplasia (2009) 1.10
Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3. Diabetes (2005) 1.08
Galectins in acute and chronic inflammation. Ann N Y Acad Sci (2012) 1.07
Allergen-induced airway remodeling is impaired in galectin-3-deficient mice. J Immunol (2010) 1.07
Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells. Oncogene (2003) 1.05
Hepatocyte growth factor suppresses profibrogenic signal transduction via nuclear export of Smad3 with galectin-7. Gastroenterology (2008) 1.04
Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis. Am J Pathol (2009) 1.03
Mast cells and immunological skin diseases. Clin Rev Allergy Immunol (2007) 1.03
Suppression of tumor growth by galectin-7 gene transfer. Cancer Res (2004) 1.02
The roles of Galectin-3 in autoimmunity and tumor progression. Immunol Res (2012) 1.01
The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus. PLoS Pathog (2012) 1.01
Participation of pigment epithelium in ocular immune privilege. 3. Epithelia cultured from iris, ciliary body, and retina suppress T-cell activation by partially non-overlapping mechanisms. Ocul Immunol Inflamm (2003) 1.01
LPS-induced galectin-3 oligomerization results in enhancement of neutrophil activation. PLoS One (2011) 1.01
The constitutive expression of galectin-3 is downregulated in the intestinal epithelia of Crohn's disease patients, and tumour necrosis factor alpha decreases the level of galectin-3-specific mRNA in HCT-8 cells. Eur J Gastroenterol Hepatol (2002) 0.99
Galectin-12 is required for adipogenic signaling and adipocyte differentiation. J Biol Chem (2004) 0.99
B cell depletion therapy exacerbates murine primary biliary cirrhosis. Hepatology (2010) 0.99
Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. Am J Pathol (2007) 0.99
Sensitizing effect of galectin-7 in urothelial cancer to cisplatin through the accumulation of intracellular reactive oxygen species. Cancer Res (2007) 0.99
The COOH-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth. Cancer Res (2006) 0.98
Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration. J Invest Dermatol (2012) 0.98
An anti-apoptotic role for galectin-3 in diffuse large B-cell lymphomas. Am J Pathol (2004) 0.98
Biochemical characterization and functional studies of Acanthamoeba mannose-binding protein. Infect Immun (2005) 0.97
Association of a macrophage galactoside-binding protein with Mycobacterium-containing phagosomes. Cell Microbiol (2002) 0.97
Changes in galectin-7 and cytokeratin-19 expression during the progression of malignancy in thyroid tumors: diagnostic and biological implications. Mod Pathol (2002) 0.95
Galectin-3 negatively regulates dendritic cell production of IL-23/IL-17-axis cytokines in infection by Histoplasma capsulatum. J Immunol (2013) 0.95
In vitro pathogenicity of Acanthamoeba is associated with the expression of the mannose-binding protein. Invest Ophthalmol Vis Sci (2006) 0.95
Rosacea: skin innate immunity gone awry? Nat Med (2007) 0.95
Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes. Exp Diabetes Res (2007) 0.94
Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo. Am J Physiol Gastrointest Liver Physiol (2011) 0.94
Effects of growth factors (EGF, PDGF-BB and TGF-beta 1) on cultured equine epithelial cells and keratocytes: implications for wound healing. Vet Ophthalmol (2003) 0.93
Nuclear localization of Galectin-3 in transformed thyroid cells: a role in transcriptional regulation. Biochem Biophys Res Commun (2003) 0.93
Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation. J Invest Dermatol (2008) 0.93
Involvement of protein tyrosine kinase in Toll-like receptor 4-mediated NF-kappa B activation in human peripheral blood monocytes. Am J Physiol Lung Cell Mol Physiol (2002) 0.93
IL-1 receptor-associated kinase and low molecular weight GTPase RhoA signal molecules are required for bacterial lipopolysaccharide-induced cytokine gene transcription. J Immunol (2002) 0.93