Published in Clin Rev Allergy Immunol on October 01, 2007
Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment. Cancer Cell (2009) 2.19
Mesenchymal stem cell 1 (MSC1)-based therapy attenuates tumor growth whereas MSC2-treatment promotes tumor growth and metastasis. PLoS One (2012) 1.18
Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease. J Invest Dermatol (2008) 1.10
Redefinition of the human mast cell transcriptome by deep-CAGE sequencing. Blood (2014) 1.09
Lesional and nonlesional skin from patients with untreated juvenile dermatomyositis displays increased numbers of mast cells and mature plasmacytoid dendritic cells. Arthritis Rheum (2010) 1.00
Mast Cells are Important Modifiers of Autoimmune Disease: With so Much Evidence, Why is There Still Controversy? Front Immunol (2012) 0.93
Mast cells as cellular sensors in inflammation and immunity. Front Immunol (2011) 0.89
IgE-mediated mast cell responses are inhibited by thymol-mediated, activation-induced cell death in skin inflammation. J Allergy Clin Immunol (2014) 0.82
Effects of Ixeris dentata water extract and caffeic acid on allergic inflammation in vivo and in vitro. BMC Complement Altern Med (2015) 0.78
The possible role of trauma in skin tags through the release of mast cell mediators. Indian J Dermatol (2011) 0.77
A comparative analysis of mast cell quantification in five common dermatoses: lichen simplex chronicus, psoriasis, lichen planus, lupus, and insect bite/allergic contact dermatitis/nummular dermatitis. ISRN Dermatol (2012) 0.77
Effect of Dangguibohyul-Tang, a Mixed Extract of Astragalus membranaceus and Angelica sinensis, on Allergic and Inflammatory Skin Reaction Compared with Single Extracts of Astragalus membranaceus or Angelica sinensis. Evid Based Complement Alternat Med (2016) 0.76
Korean Red Ginseng improves atopic dermatitis-like skin lesions by suppressing expression of proinflammatory cytokines and chemokines in vivo and in vitro. J Ginseng Res (2016) 0.75
Functional testing of topical skin formulations using an optimised ex vivo skin organ culture model. Arch Dermatol Res (2016) 0.75
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. Am J Pathol (2008) 2.83
Galectins: structure, function and therapeutic potential. Expert Rev Mol Med (2008) 2.61
Critical role of galectin-3 in phagocytosis by macrophages. J Clin Invest (2003) 2.18
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death. J Immunol (2006) 2.14
Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI. Proc Natl Acad Sci U S A (2003) 1.94
Galectin-3 induces death of Candida species expressing specific beta-1,2-linked mannans. J Immunol (2006) 1.61
Galectins-3 and -7, but not galectin-1, play a role in re-epithelialization of wounds. J Biol Chem (2002) 1.58
Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice. Arthritis Res Ther (2011) 1.44
Plasma platelet-derived microparticles in patients with connective tissue diseases. J Rheumatol (2011) 1.44
Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. J Invest Dermatol (2008) 1.42
Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med (2010) 1.41
Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling. J Biol Chem (2008) 1.40
Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis. Hepatology (2013) 1.33
Galectin-3 is a negative regulator of lipopolysaccharide-mediated inflammation. J Immunol (2008) 1.29
Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.28
Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on alpha3beta1 integrin. J Cell Sci (2009) 1.26
Cell mechanics using atomic force microscopy-based single-cell compression. Langmuir (2006) 1.26
Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release. J Biol Chem (2001) 1.25
Galectin-3 mediates IL-4-induced survival and differentiation of B cells: functional cross-talk and implications during Trypanosoma cruzi infection. J Immunol (2004) 1.24
Role of galectin-3 in human pulmonary fibrosis. Allergol Int (2007) 1.24
Galectin-3 functions as an adhesion molecule to support eosinophil rolling and adhesion under conditions of flow. J Immunol (2007) 1.23
Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol (2004) 1.22
LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition. J Immunol (2004) 1.22
Galectin 3 and its binding protein in rheumatoid arthritis. Arthritis Rheum (2003) 1.20
Regulation of cellular homeostasis by galectins. Glycoconj J (2004) 1.20
Diagnostic accuracy of serum 1,3-β-D-glucan for pneumocystis jiroveci pneumonia, invasive candidiasis, and invasive aspergillosis: systematic review and meta-analysis. J Clin Microbiol (2011) 1.18
Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner. J Biol Chem (2008) 1.16
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Proc Natl Acad Sci U S A (2009) 1.16
Toxoplasma gondii infection reveals a novel regulatory role for galectin-3 in the interface of innate and adaptive immunity. Am J Pathol (2006) 1.14
Galectin-3 regulates T-cell functions. Immunol Rev (2009) 1.14
Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells. J Invest Dermatol (2008) 1.13
IgE-dependent mast cell activation potentiates airway responses in murine asthma models. J Immunol (2002) 1.13
Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression. J Immunol (2006) 1.12
The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling. J Biol Chem (2009) 1.12
Galectins in apoptosis. Methods Enzymol (2006) 1.12
The immunological potential of galectin-1 and -3. Autoimmun Rev (2008) 1.11
Galectin-3 preserves renal tubules and modulates extracellular matrix remodeling in progressive fibrosis. Am J Physiol Renal Physiol (2010) 1.10
Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3. Diabetes (2005) 1.08
Allergen-induced airway remodeling is impaired in galectin-3-deficient mice. J Immunol (2010) 1.07
Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells. Oncogene (2003) 1.05
Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis. Am J Pathol (2009) 1.03
Suppression of tumor growth by galectin-7 gene transfer. Cancer Res (2004) 1.02
The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus. PLoS Pathog (2012) 1.01
LPS-induced galectin-3 oligomerization results in enhancement of neutrophil activation. PLoS One (2011) 1.01
The constitutive expression of galectin-3 is downregulated in the intestinal epithelia of Crohn's disease patients, and tumour necrosis factor alpha decreases the level of galectin-3-specific mRNA in HCT-8 cells. Eur J Gastroenterol Hepatol (2002) 0.99
Galectin-12 is required for adipogenic signaling and adipocyte differentiation. J Biol Chem (2004) 0.99
B cell depletion therapy exacerbates murine primary biliary cirrhosis. Hepatology (2010) 0.99
Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. Am J Pathol (2007) 0.99
The COOH-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth. Cancer Res (2006) 0.98
Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration. J Invest Dermatol (2012) 0.98
An anti-apoptotic role for galectin-3 in diffuse large B-cell lymphomas. Am J Pathol (2004) 0.98
Association of a macrophage galactoside-binding protein with Mycobacterium-containing phagosomes. Cell Microbiol (2002) 0.97
Changes in galectin-7 and cytokeratin-19 expression during the progression of malignancy in thyroid tumors: diagnostic and biological implications. Mod Pathol (2002) 0.95
Podoplanin is an inflammatory protein upregulated in Th17 cells in SKG arthritic joints. Mol Immunol (2012) 0.95
Galectin-3 negatively regulates dendritic cell production of IL-23/IL-17-axis cytokines in infection by Histoplasma capsulatum. J Immunol (2013) 0.95
Rosacea: skin innate immunity gone awry? Nat Med (2007) 0.95
Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes. Exp Diabetes Res (2007) 0.94
Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo. Am J Physiol Gastrointest Liver Physiol (2011) 0.94
Nuclear localization of Galectin-3 in transformed thyroid cells: a role in transcriptional regulation. Biochem Biophys Res Commun (2003) 0.93
Involvement of protein tyrosine kinase in Toll-like receptor 4-mediated NF-kappa B activation in human peripheral blood monocytes. Am J Physiol Lung Cell Mol Physiol (2002) 0.93
Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation. J Invest Dermatol (2008) 0.93
IL-1 receptor-associated kinase and low molecular weight GTPase RhoA signal molecules are required for bacterial lipopolysaccharide-induced cytokine gene transcription. J Immunol (2002) 0.93
Higher bone marrow LGALS3 expression is an independent unfavorable prognostic factor for overall survival in patients with acute myeloid leukemia. Blood (2013) 0.92
Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation. J Allergy Clin Immunol (2012) 0.92
Lack of galectin-3 alters the balance of innate immune cytokines and confers resistance to Rhodococcus equi infection. Eur J Immunol (2008) 0.92
Galectin-3 stimulates preadipocyte proliferation and is up-regulated in growing adipose tissue. Obesity (Silver Spring) (2007) 0.92
Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death. Blood (2012) 0.91
Dissection of antigen-specific humoral and cellular immune responses for the development of experimental immune-mediated blepharoconjunctivitis in C57BL/6 mice. Curr Eye Res (2005) 0.91
Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice. Proc Natl Acad Sci U S A (2011) 0.90
Molecular basis of interaction between NG2 proteoglycan and galectin-3. J Cell Biochem (2006) 0.89
Galectin-3 regulates peritoneal B1-cell differentiation into plasma cells. Glycobiology (2009) 0.89
Nonalcoholic steatohepatitis and hepatocellular carcinoma in galectin-3 knockout mice. Hepatol Res (2008) 0.89
Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade. Int Immunol (2009) 0.88
Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunity. PLoS One (2009) 0.87
Galectin-7 as a potential mediator of corneal epithelial cell migration. Arch Ophthalmol (2003) 0.87
A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist. PLoS One (2010) 0.87
Inducible deletion of the Blimp-1 gene in adult epidermis causes granulocyte-dominated chronic skin inflammation in mice. Proc Natl Acad Sci U S A (2013) 0.86
Genetic background determines susceptibility to experimental immune-mediated blepharoconjunctivitis: comparison of Balb/c and C57BL/6 mice. Exp Eye Res (2005) 0.86
Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Brain Behav (2012) 0.86
Galectin-3 negatively regulates the frequency and function of CD4(+) CD25(+) Foxp3(+) regulatory T cells and influences the course of Leishmania major infection. Eur J Immunol (2013) 0.86
SS-A/Ro52 promotes apoptosis by regulating Bcl-2 production. Biochem Biophys Res Commun (2011) 0.85
Galectin-3 plays a modulatory role in the life span and activation of murine neutrophils during early Toxoplasma gondii infection. Immunobiology (2009) 0.85
Galectin-3 modulates Th17 responses by regulating dendritic cell cytokines. Am J Pathol (2013) 0.85
Galectin-3 disruption impaired tumoral angiogenesis by reducing VEGF secretion from TGFβ1-induced macrophages. Cancer Med (2014) 0.85
The antigen presentation function of bone marrow-derived mast cells is spatiotemporally restricted to a subset expressing high levels of cell surface FcepsilonRI and MHC II. BMC Immunol (2010) 0.85
Galectins and neuroinflammation. Adv Neurobiol (2014) 0.85
Activation of the Wnt/beta-catenin signaling pathway during oral carcinogenesis process is not influenced by the absence of galectin-3 in mice. Anticancer Res (2011) 0.85
New alternatively spliced form of galectin-3, a member of the beta-galactoside-binding animal lectin family, contains a predicted transmembrane-spanning domain and a leucine zipper motif. J Biol Chem (2002) 0.85
A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis. PLoS One (2013) 0.84
Roles of galectin-3 in immune responses. Arch Immunol Ther Exp (Warsz) (2006) 0.84
Mast cells. Receptors, secretagogues, and signaling. Clin Rev Allergy Immunol (2002) 0.83
Lack of galectin-3 alleviates trypanosomiasis-associated anemia of inflammation. Immunobiology (2010) 0.83
Role of galectin-3 in prion infections of the CNS. Biochem Biophys Res Commun (2007) 0.83
CD45RA-Foxp3(high) activated/effector regulatory T cells in the CCR7 + CD45RA-CD27 + CD28+central memory subset are decreased in peripheral blood from patients with rheumatoid arthritis. Biochem Biophys Res Commun (2013) 0.83
Galectin-3 and the skin. J Dermatol Sci (2011) 0.82
Absence of galectin-3 does not affect the development of experimental tongue carcinomas in mice. Exp Mol Pathol (2010) 0.81
Critical role of IgE-dependent mast cell activation in a murine model of allergic conjunctivitis. J Allergy Clin Immunol (2009) 0.81
Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection. PLoS One (2011) 0.81