Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells.

PubWeight™: 0.93‹?›

🔗 View Article (PMC 3392929)

Published in J Cell Biol on July 09, 2012

Authors

Yi Fan1, Sandeepa M Eswarappa, Masahiro Hitomi, Paul L Fox

Author Affiliations

1: Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

Articles citing this

Dynamic localization of G-actin during membrane protrusion in neuronal motility. Curr Biol (2013) 0.98

Regulation and control of myosin-I by the motor and light chain-binding domains. Trends Cell Biol (2012) 0.97

Functional roles for myosin 1c in cellular signaling pathways. Cell Signal (2012) 0.92

The myosin motor Myo1c is required for VEGFR2 delivery to the cell surface and for angiogenic signaling. Am J Physiol Heart Circ Physiol (2012) 0.88

Myo1c is an unconventional myosin required for zebrafish glomerular development. Kidney Int (2013) 0.86

Two functionally distinct sources of actin monomers supply the leading edge of lamellipodia. Cell Rep (2015) 0.85

Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation. Biol Open (2013) 0.83

Class I myosins have overlapping and specialized functions in left-right asymmetric development in Drosophila. Genetics (2015) 0.80

Transcriptional network analysis reveals that AT1 and AT2 angiotensin II receptors are both involved in the regulation of genes essential for glioma progression. PLoS One (2014) 0.77

Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1. Mol Cell Biol (2016) 0.76

The role of myosin 1c and myosin 1b in surfactant exocytosis. J Cell Sci (2016) 0.75

G-actin guides p53 nuclear transport: potential contribution of monomeric actin in altered localization of mutant p53. Sci Rep (2016) 0.75

Myosin-I molecular motors at a glance. J Cell Sci (2016) 0.75

Model of turnover kinetics in the lamellipodium: implications of slow- and fast- diffusing capping protein and Arp2/3 complex. Phys Biol (2016) 0.75

Nuclear myosin I regulates cell membrane tension. Sci Rep (2016) 0.75

Articles cited by this

Cellular motility driven by assembly and disassembly of actin filaments. Cell (2003) 26.05

A photoactivatable GFP for selective photolabeling of proteins and cells. Science (2002) 12.02

Two distinct actin networks drive the protrusion of migrating cells. Science (2004) 7.69

Intracellular localization of messenger RNAs for cytoskeletal proteins. Cell (1986) 4.53

Single-molecule speckle analysis of actin filament turnover in lamellipodia. Science (2002) 4.27

EGF stimulates an increase in actin nucleation and filament number at the leading edge of the lamellipod in mammary adenocarcinoma cells. J Cell Sci (1998) 3.12

Motor domain-dependent localization of myo1b (myr-1). Curr Biol (2001) 2.88

Regulation of actin dynamics in rapidly moving cells: a quantitative analysis. Biophys J (2002) 2.84

Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c. Nature (2002) 2.51

Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor. Mol Biol Cell (2002) 2.40

The physiological significance of beta -actin mRNA localization in determining cell polarity and directional motility. Proc Natl Acad Sci U S A (2001) 2.40

How and why does beta-actin mRNA target? Biol Cell (2005) 2.38

Relating biochemistry and function in the myosin superfamily. Curr Opin Cell Biol (2004) 2.31

Arp2/3 complex interactions and actin network turnover in lamellipodia. EMBO J (2008) 2.30

Myosin I can act as a molecular force sensor. Science (2008) 2.21

Role of actin-filament disassembly in lamellipodium protrusion in motile cells revealed using the drug jasplakinolide. Curr Biol (1999) 2.21

Fission yeast myosin-I, Myo1p, stimulates actin assembly by Arp2/3 complex and shares functions with WASp. J Cell Biol (2000) 2.13

Rapid actin transport during cell protrusion. Science (2003) 2.11

Growing an actin gel on spherical surfaces. Biophys J (2000) 2.06

CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes. Cell Metab (2008) 1.96

Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c. Dev Cell (2007) 1.88

Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast. J Cell Biol (2005) 1.84

Simultaneous measurements of actin filament turnover, filament fraction, and monomer diffusion in endothelial cells. Biophys J (1998) 1.77

Myo1c binds phosphoinositides through a putative pleckstrin homology domain. Mol Biol Cell (2006) 1.74

Intracellular fluid flow in rapidly moving cells. Nat Cell Biol (2009) 1.65

A two-tiered mechanism by which Cdc42 controls the localization and activation of an Arp2/3-activating motor complex in yeast. J Cell Biol (2001) 1.44

F- and G-actin concentrations in lamellipodia of moving cells. PLoS One (2009) 1.41

Localization and dynamics of nonfilamentous actin in cultured cells. J Cell Biol (1993) 1.41

Domain structure of a mammalian myosin I beta. Proc Natl Acad Sci U S A (1994) 1.32

Myosin at work: motor adaptations for a variety of cellular functions. Biochim Biophys Acta (2006) 1.25

Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane. Mol Cell Biol (2011) 1.23

Myosin IXb is a single-headed minus-end-directed processive motor. Nat Cell Biol (2002) 1.23

Myosin-IXb is a single-headed and processive motor. J Biol Chem (2002) 1.19

Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension. J Cell Biol (2011) 1.17

Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network. Nat Cell Biol (2011) 1.16

A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes. Mol Cell Biol (2008) 1.15

Spatial coordination of actin polymerization and ILK-Akt2 activity during endothelial cell migration. Dev Cell (2009) 1.14

Membrane microviscosity regulates endothelial cell motility. Nat Cell Biol (2002) 1.14

Specific changes to the mechanism of cell locomotion induced by overexpression of beta-actin. J Cell Sci (2001) 1.14

Growing actin networks form lamellipodium and lamellum by self-assembly. Biophys J (2008) 1.10

The effect of diffusion, depolymerization and nucleation promoting factors on actin gel growth. Eur Biophys J (2003) 1.08

Myosin motor Myo1c and its receptor NEMO/IKK-gamma promote TNF-alpha-induced serine307 phosphorylation of IRS-1. J Cell Biol (2006) 1.07

Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration. Proc Natl Acad Sci U S A (2009) 1.03

Polarization of plasma membrane microviscosity during endothelial cell migration. Dev Cell (2004) 1.02

Polymerization of G-actin by myosin subfragment 1. J Biol Chem (1988) 0.99

A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity. Biochemistry (2011) 0.91

Interactions between G-actin and myosin subfragment 1: immunochemical probing of the NH2-terminal segment on actin. Biochemistry (1990) 0.87

Articles by these authors

Translational control by the 3'-UTR: the ends specify the means. Trends Biochem Sci (2003) 4.00

Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. J Clin Invest (2004) 3.63

Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation. Cell (2004) 3.12

Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. Cell (2003) 3.07

Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. J Biol Chem (2002) 2.94

A stress-responsive RNA switch regulates VEGFA expression. Nature (2008) 2.58

WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expression. Mol Cell (2008) 2.34

Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake. Nat Neurosci (2013) 2.30

TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI. Nat Cell Biol (2010) 2.17

Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression. Cell (2012) 2.06

The GAIT system: a gatekeeper of inflammatory gene expression. Trends Biochem Sci (2009) 1.88

DAPK-ZIPK-L13a axis constitutes a negative-feedback module regulating inflammatory gene expression. Mol Cell (2008) 1.70

Aminoacyl-tRNA synthetases in medicine and disease. EMBO Mol Med (2013) 1.67

Ras is active throughout the cell cycle, but is able to induce cyclin D1 only during G2 phase. Cell Cycle (2002) 1.64

A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity. EMBO J (2007) 1.59

Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region. Mol Cell Biol (2003) 1.53

L13a blocks 48S assembly: role of a general initiation factor in mRNA-specific translational control. Mol Cell (2007) 1.47

Macromolecular complexes as depots for releasable regulatory proteins. Trends Biochem Sci (2007) 1.45

Repression of VEGFA by CA-rich element-binding microRNAs is modulated by hnRNP L. EMBO J (2011) 1.44

Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesis. Oncogene (2005) 1.39

Differential caveolin-1 polarization in endothelial cells during migration in two and three dimensions. Mol Biol Cell (2003) 1.31

Two-site phosphorylation of EPRS coordinates multimodal regulation of noncanonical translational control activity. Mol Cell (2009) 1.27

Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development. Blood (2006) 1.23

Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. J Clin Invest (2013) 1.21

Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A. J Exp Med (2013) 1.21

GAPDH regulates cellular heme insertion into inducible nitric oxide synthase. Proc Natl Acad Sci U S A (2010) 1.17

Unexpected role of ceruloplasmin in intestinal iron absorption. Cell Metab (2005) 1.16

Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity. Genes Dev (2012) 1.15

Spatial coordination of actin polymerization and ILK-Akt2 activity during endothelial cell migration. Dev Cell (2009) 1.14

Membrane microviscosity regulates endothelial cell motility. Nat Cell Biol (2002) 1.14

Regulation and dysregulation of 3'UTR-mediated translational control. Curr Opin Genet Dev (2013) 1.14

Post-transcriptional regulation of cyclin D1 expression during G2 phase. Oncogene (2002) 1.13

Variations in cyclin D1 levels through the cell cycle determine the proliferative fate of a cell. Cell Div (2006) 1.13

Stimulus-dependent phosphorylation of profilin-1 in angiogenesis. Nat Cell Biol (2012) 1.12

Role of ceruloplasmin in macrophage iron efflux during hypoxia. J Biol Chem (2003) 1.10

Clinical and genetic association of serum ceruloplasmin with cardiovascular risk. Arterioscler Thromb Vasc Biol (2011) 1.10

Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages. Mol Cell Biol (2012) 1.07

Kindlin-2 regulates hemostasis by controlling endothelial cell-surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism. Blood (2013) 1.06

IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production. EMBO J (2013) 1.06

Phosphorylation of glutamyl-prolyl tRNA synthetase by cyclin-dependent kinase 5 dictates transcript-selective translational control. Proc Natl Acad Sci U S A (2011) 1.06

Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels. BMC Cell Biol (2006) 1.03

The critical role of IL-1 receptor-associated kinase 4-mediated NF-κB activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis. J Immunol (2011) 1.02

Polarization of plasma membrane microviscosity during endothelial cell migration. Dev Cell (2004) 1.02

Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation. Mol Cell (2012) 1.01

Protein kinase Cdelta-dependent phosphorylation of syndecan-4 regulates cell migration. Circ Res (2005) 0.99

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. J Exp Med (2014) 0.98

Site-specific nitration of apolipoprotein A-I at tyrosine 166 is both abundant within human atherosclerotic plaque and dysfunctional. J Biol Chem (2014) 0.98

A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation. Sci Signal (2011) 0.98

Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance. Immunity (2012) 0.97

HOXA9 methylation by PRMT5 is essential for endothelial cell expression of leukocyte adhesion molecules. Mol Cell Biol (2012) 0.96

Function and distribution of apolipoprotein A1 in the artery wall are markedly distinct from those in plasma. Circulation (2013) 0.96

Protective role of macrophage-derived ceruloplasmin in inflammatory bowel disease. Gut (2012) 0.94

Expression of Sorsby's fundus dystrophy mutations in human retinal pigment epithelial cells reduces matrix metalloproteinase inhibition and may promote angiogenesis. J Biol Chem (2002) 0.94

Destabilization of cyclin D1 message plays a critical role in cell cycle exit upon mitogen withdrawal. Oncogene (2005) 0.94

Role of reactive oxygen species in inhibition of endothelial cell migration by oxidized low-density lipoprotein. J Vasc Surg (2004) 0.94

Glioma stem cell maintenance: the role of the microenvironment. Curr Pharm Des (2011) 0.93

Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism involving its 3'-untranslated region: implications in neurodegenerative diseases. J Biol Chem (2008) 0.92

Needleless vaccine delivery using micro-shock waves. Clin Vaccine Immunol (2011) 0.90

HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization. J Immunol (2013) 0.90

Cancer stem cell-specific scavenger receptor 36 drives glioblastoma progression. Stem Cells (2014) 0.89

The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA. PLoS Biol (2013) 0.88

Evolution of function of a fused metazoan tRNA synthetase. Mol Biol Evol (2010) 0.88

Anemia and impaired stress-induced erythropoiesis in aceruloplasminemic mice. Blood Cells Mol Dis (2004) 0.88

Regulation of macrophage ceruloplasmin gene expression: one paradigm of 3'-UTR-mediated translational control. Mol Cells (2005) 0.88

Oxidative stress inhibits caveolin-1 palmitoylation and trafficking in endothelial cells. Biochem J (2002) 0.86

Aptamer identification of brain tumor-initiating cells. Cancer Res (2013) 0.86

Cell cycle studies based upon quantitative image analysis. Cytometry A (2008) 0.85

Non-catalytic regulation of gene expression by aminoacyl-tRNA synthetases. Top Curr Chem (2014) 0.85

Regulation of ceruloplasmin in human hepatic cells by redox active copper: identification of a novel AP-1 site in the ceruloplasmin gene. Biochem J (2007) 0.83

SopB of Salmonella enterica serovar Typhimurium is a potential DNA vaccine candidate in conjugation with live attenuated bacteria. Vaccine (2009) 0.82

Alpha-tocopherol preserves endothelial cell migration in the presence of cell-oxidized low-density lipoprotein by inhibiting changes in cell membrane fluidity. J Vasc Surg (2004) 0.82

Oxidative stress, caveolae and caveolin-1. Subcell Biochem (2004) 0.81

Caveolin-1 polarization in migrating endothelial cells is directed by substrate topology not chemoattractant gradient. Cell Motil Cytoskeleton (2006) 0.81

Dual role of insulin in transcriptional regulation of the acute phase reactant ceruloplasmin. J Biol Chem (2002) 0.80

Translational control of ceruloplasmin gene expression: beyond the IRE. Biol Res (2006) 0.80

A truncated tRNA synthetase directs a "translational trickle" of gene expression. Cell Cycle (2012) 0.77

Translational control mechanisms in angiogenesis and vascular biology. Curr Atheroscler Rep (2015) 0.76

Citric acid cycle and the origin of MARS. Trends Biochem Sci (2013) 0.76

Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression. Sci Signal (2013) 0.76

Sex lethal and upstream ORFs: a bait-and-trap system for ribosomes. Genome Biol (2011) 0.75

Equality of the sexes: found in translation. Cell (2005) 0.75

Altering the balance between pathogen containing vacuoles and lysosomes: a lesson from Salmonella. Virulence (2010) 0.75