Published in Nucleic Acids Res on September 01, 2002
Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components. Genes Dev (2007) 3.75
A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J (2003) 2.73
Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex. Mol Cell Biol (2003) 2.21
Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators. J Mol Biol (2009) 1.85
RNA-directed DNA methylation requires an AGO4-interacting member of the SPT5 elongation factor family. EMBO Rep (2009) 1.75
DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation. Genes Dev (2009) 1.64
Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J (2003) 1.48
Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress. Cell (2013) 1.46
Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif. Nucleic Acids Res (2010) 1.38
TEFM (c17orf42) is necessary for transcription of human mtDNA. Nucleic Acids Res (2011) 1.38
A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS. Proc Natl Acad Sci U S A (2005) 1.36
Core structure of the yeast spt4-spt5 complex: a conserved module for regulation of transcription elongation. Structure (2008) 1.30
The elongata mutants identify a functional Elongator complex in plants with a role in cell proliferation during organ growth. Proc Natl Acad Sci U S A (2005) 1.26
DRL1, a homolog of the yeast TOT4/KTI12 protein, has a function in meristem activity and organ growth in plants. Plant Cell (2003) 1.18
Crystal structure and RNA binding of the Tex protein from Pseudomonas aeruginosa. J Mol Biol (2008) 1.15
Spartan/C1orf124 is important to prevent UV-induced mutagenesis. Cell Cycle (2012) 1.14
The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation. Biochim Biophys Acta (2012) 1.11
Identification of a regulator of transcription elongation as an accessory factor for the human Mediator coactivator. Proc Natl Acad Sci U S A (2007) 1.10
Structural analysis of Rtt106p reveals a DNA binding role required for heterochromatin silencing. J Biol Chem (2009) 1.04
Highly divergent RfaH orthologs from pathogenic proteobacteria can substitute for Escherichia coli RfaH both in vivo and in vitro. J Bacteriol (2004) 1.02
Domain organization of the yeast histone chaperone FACT: the conserved N-terminal domain of FACT subunit Spt16 mediates recovery from replication stress. Nucleic Acids Res (2004) 1.01
NusG-Spt5 proteins-Universal tools for transcription modification and communication. Chem Rev (2013) 1.01
Transcription by an archaeal RNA polymerase is slowed but not blocked by an archaeal nucleosome. J Bacteriol (2004) 1.00
The spt5 C-terminal region recruits yeast 3' RNA cleavage factor I. Mol Cell Biol (2012) 0.99
Two GW repeat proteins interact with Tetrahymena thermophila argonaute and promote genome rearrangement. Mol Cell Biol (2009) 0.97
Spt6 is required for heterochromatic silencing in the fission yeast Schizosaccharomyces pombe. Mol Cell Biol (2011) 0.93
Yeast transcription elongation factor Spt5 associates with RNA polymerase I and RNA polymerase II directly. J Biol Chem (2011) 0.91
Crystal structure of elongator subcomplex Elp4-6. J Biol Chem (2012) 0.91
Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J Mol Biol (2011) 0.91
Insights into how Spt5 functions in transcription elongation and repressing transcription coupled DNA repair. Nucleic Acids Res (2014) 0.87
The recruitment of the Saccharomyces cerevisiae Paf1 complex to active genes requires a domain of Rtf1 that directly interacts with the Spt4-Spt5 complex. Mol Cell Biol (2013) 0.85
Solution structure of the hypothetical protein YqgF from Escherichia coli reveals an RNAse H fold. J Biomol NMR (2003) 0.84
Characterization of the Schizosaccharomyces pombe Spt5-Spt4 complex. RNA (2009) 0.84
Elongator: an ancestral complex driving transcription and migration through protein acetylation. J Biomed Biotechnol (2011) 0.83
Ubiquitous transcription factors display structural plasticity and diverse functions: NusG proteins - Shifting shapes and paradigms. Bioessays (2015) 0.82
Diverse roles of RNA polymerase II-associated factor 1 complex in different subpathways of nucleotide excision repair. J Biol Chem (2011) 0.81
Drosophila poly suggests a novel role for the Elongator complex in insulin receptor-target of rapamycin signalling. Open Biol (2012) 0.77
Crystal Structure of Human SSRP1 Middle Domain Reveals a Role in DNA Binding. Sci Rep (2015) 0.77
Crystallization and halide phasing of the C-terminal domain of human KIN17. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.77
The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein. Protein Sci (2016) 0.76
Transcription factors that influence RNA polymerases I and II: To what extent is mechanism of action conserved? Biochim Biophys Acta (2016) 0.75
A meiosis-specific Spt5 homolog involved in non-coding transcription. Nucleic Acids Res (2017) 0.75
Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nat Struct Mol Biol (2017) 0.75
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47
Profile hidden Markov models. Bioinformatics (1998) 56.04
The Pfam protein families database. Nucleic Acids Res (2002) 51.34
The COG database: new developments in phylogenetic classification of proteins from complete genomes. Nucleic Acids Res (2001) 43.17
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science (2000) 28.25
BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences. FEMS Microbiol Lett (1999) 25.40
Recent improvements to the SMART domain-based sequence annotation resource. Nucleic Acids Res (2002) 25.06
Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements. Nucleic Acids Res (2001) 22.33
SEAVIEW and PHYLO_WIN: two graphic tools for sequence alignment and molecular phylogeny. Comput Appl Biosci (1996) 20.45
Detecting protein function and protein-protein interactions from genome sequences. Science (1999) 18.69
CDD: a database of conserved domain alignments with links to domain three-dimensional structure. Nucleic Acids Res (2002) 18.54
Detection of conserved segments in proteins: iterative scanning of sequence databases with alignment blocks. Proc Natl Acad Sci U S A (1994) 18.46
Prediction of protein secondary structure at better than 70% accuracy. J Mol Biol (1993) 17.53
The use of gene clusters to infer functional coupling. Proc Natl Acad Sci U S A (1999) 16.35
Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell (2002) 6.25
Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae. Genes Dev (1998) 5.16
The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins. Nature (1999) 4.69
Exchange of RNA polymerase II initiation and elongation factors during gene expression in vivo. Mol Cell (2002) 4.35
Role of Cue1p in ubiquitination and degradation at the ER surface. Science (1997) 4.18
Comparative genomics and evolution of proteins involved in RNA metabolism. Nucleic Acids Res (2002) 4.00
A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme. Mol Cell (1999) 3.80
SURVEY AND SUMMARY: holliday junction resolvases and related nucleases: identification of new families, phyletic distribution and evolutionary trajectories. Nucleic Acids Res (2000) 3.56
Systematic identification of novel protein domain families associated with nuclear functions. Genome Res (2002) 3.50
Removing near-neighbour redundancy from large protein sequence collections. Bioinformatics (1998) 3.47
The Paf1 complex physically and functionally associates with transcription elongation factors in vivo. EMBO J (2002) 3.44
CHROMA: consensus-based colouring of multiple alignments for publication. Bioinformatics (2001) 3.30
Evidence that Spt6p controls chromatin structure by a direct interaction with histones. Science (1996) 3.23
The helix-hairpin-helix DNA-binding motif: a structural basis for non-sequence-specific recognition of DNA. Nucleic Acids Res (1996) 3.20
RNA polymerase II elongation through chromatin. Nature (2000) 2.94
Applying motif and profile searches. Methods Enzymol (1996) 2.78
Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster. Genes Dev (2000) 2.78
Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mol Cell Biol (2002) 2.60
Structure and function of the human transcription elongation factor DSIF. J Biol Chem (1999) 2.19
RfaH and the ops element, components of a novel system controlling bacterial transcription elongation. Mol Microbiol (1997) 2.00
Characterization of a six-subunit holo-elongator complex required for the regulated expression of a group of genes in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.87
GreA protein: a transcription elongation factor from Escherichia coli. Proc Natl Acad Sci U S A (1992) 1.85
A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage. Nature (2002) 1.80
KOW: a novel motif linking a bacterial transcription factor with ribosomal proteins. Trends Biochem Sci (1996) 1.74
RNA polymerase II elongator holoenzyme is composed of two discrete subcomplexes. J Biol Chem (2001) 1.65
Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction. Biochem J (2000) 1.58
Methanobacterium thermoautotrophicum RNA polymerase and transcription in vitro. J Bacteriol (1999) 1.34
A second catalytic domain in the Elp3 histone acetyltransferases: a candidate for histone demethylase activity? Trends Biochem Sci (2002) 1.31
The yeast protein complex containing cdc68 and pob3 mediates core-promoter repression through the cdc68 N-terminal domain. Genetics (1998) 1.26
Interaction of FACT, SSRP1, and the high mobility group (HMG) domain of SSRP1 with DNA damaged by the anticancer drug cisplatin. J Biol Chem (2001) 1.10
The mouse Enhancer trap locus 1 (Etl-1): a novel mammalian gene related to Drosophila and yeast transcriptional regulator genes. Mech Dev (1992) 1.10
A new gene locus of Bordetella pertussis defines a novel family of prokaryotic transcriptional accessory proteins. J Bacteriol (1996) 1.07
Chromatin elongation factors. Curr Opin Genet Dev (2002) 1.06
A fission yeast gene encoding a protein that preferentially associates with curved DNA. Yeast (1994) 1.03
Approximate statistics of gapped alignments. J Comput Biol (1999) 1.02
A yeast SH2 domain. Trends Biochem Sci (1993) 1.00
Identification and expression of the cDNA of KIN17, a zinc-finger gene located on mouse chromosome 2, encoding a new DNA-binding protein. Nucleic Acids Res (1991) 0.94
ACRC codes for a novel nuclear protein with unusual acidic repeat tract and maps to DYT3 (dystonia parkinsonism) critical interval in xq13.1. Neurogenetics (2001) 0.88
Similar subunit architecture of archaeal and eukaryal RNA polymerases. FEMS Microbiol Lett (2001) 0.84
Archaeal chromatin: virtual or real? Proc Natl Acad Sci U S A (1997) 0.82
Clone 10d/BM28 (CDCL1), an early S-phase protein, is an important growth regulator of melanoma. Cancer Res (1997) 0.80