Published in Cancer on August 15, 2002
Fibrosis-dependent mechanisms of hepatocarcinogenesis. Hepatology (2012) 1.91
The tumor microenvironment is a dominant force in multidrug resistance. Drug Resist Updat (2012) 1.77
Reversal, maintenance or progression: what happens to the liver after a virologic cure of hepatitis C? Antiviral Res (2014) 1.17
Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling. BMC Bioinformatics (2005) 1.04
Advanced cell culture techniques for cancer drug discovery. Biology (Basel) (2014) 1.01
Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line. Mol Cancer (2010) 0.97
Hepatitis C virus infection: establishment of chronicity and liver disease progression. EXCLI J (2014) 0.90
Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer. Oncogene (2015) 0.88
Prostaglandin E2 stimulates β1-integrin expression in hepatocellular carcinoma through the EP1 receptor/PKC/NF-κB pathway. Sci Rep (2014) 0.85
Regulation of TGF-β1-Induced Pro-Apoptotic Signaling by Growth Factor Receptors and Extracellular Matrix Receptor Integrins in the Liver. Front Physiol (2011) 0.83
Comparative proteome analysis of untreated and Helicobacter pylori-treated HepG2. World J Gastroenterol (2005) 0.81
O-glycan sialylation alters galectin-3 subcellular localization and decreases chemotherapy sensitivity in gastric cancer. Oncotarget (2016) 0.75
Novel monoclonal antibody against beta 1 integrin enhances cisplatin efficacy in human lung adenocarcinoma cells. J Biomed Res (2016) 0.75
Clonal evolution of chemotherapy-resistant urothelial carcinoma. Nat Genet (2016) 0.75
Effect of vitamin K2 on the recurrence of hepatocellular carcinoma. Hepatology (2011) 3.00
Loss of PDCD4 expression in human lung cancer correlates with tumour progression and prognosis. J Pathol (2003) 2.04
Evaluation of acoustic radiation force impulse elastography for fibrosis staging of chronic liver disease: a pilot study. Liver Int (2009) 1.82
Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease. J Gastroenterol (2006) 1.63
Induction of PDCD4 tumor suppressor gene expression by RAR agonists, antiestrogen and HER-2/neu antagonist in breast cancer cells. Evidence for a role in apoptosis. Oncogene (2004) 1.63
The pathological role of visceral fat accumulation in steatosis, inflammation, and progression of nonalcoholic fatty liver disease. J Gastroenterol (2010) 1.57
Mouse inter-subspecific consomic strains for genetic dissection of quantitative complex traits. Genome Res (2008) 1.46
Mechanism of beta 1-integrin-mediated hepatoma cell growth involves p27 and S-phase kinase-associated protein 2. Hepatology (2003) 1.45
Screening for the preferred substrate sequence of transglutaminase using a phage-displayed peptide library: identification of peptide substrates for TGASE 2 and Factor XIIIA. J Biol Chem (2006) 1.37
Cys-328 of IscS and Cys-63 of IscU are the sites of disulfide bridge formation in a covalently bound IscS/IscU complex: implications for the mechanism of iron-sulfur cluster assembly. Proc Natl Acad Sci U S A (2002) 1.27
Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study. J Gastroenterol (2012) 1.27
Analysis of novel disease-related genes in bronchial asthma. Cytokine (2002) 1.22
New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. J Biol Chem (2009) 1.19
Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine. J Biol Chem (2002) 1.11
Up-regulation of PDCD4 in senescent human diploid fibroblasts. Biochem Biophys Res Commun (2002) 1.09
The physiology of phosphoinositides. Biol Pharm Bull (2007) 1.08
Alterations in D-amino acid concentrations and microbial community structures during the fermentation of red and white wines. J Biosci Bioeng (2010) 1.05
The effect of menatetrenone, a vitamin K2 analog, on disease recurrence and survival in patients with hepatocellular carcinoma after curative treatment: a pilot study. Cancer (2006) 1.05
A pilot trial of body weight reduction for nonalcoholic fatty liver disease with a home-based lifestyle modification intervention delivered in collaboration with interdisciplinary medical staff. J Gastroenterol (2009) 1.03
Fenofibrate for patients with asymptomatic primary biliary cirrhosis. World J Gastroenterol (2004) 1.02
Mode of action of a germination-specific cortex-lytic enzyme, SleC, of Clostridium perfringens S40. Biosci Biotechnol Biochem (2007) 1.01
Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor kappaB activation. Clin Cancer Res (2007) 1.00
Efficacy and safety of radiofrequency ablation for elderly hepatocellular carcinoma patients. Hepatol Res (2010) 0.99
Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. Hepatol Res (2015) 0.98
Inverse association between coffee drinking and the risk of hepatocellular carcinoma: a case-control study in Japan. Cancer Sci (2007) 0.98
Skin toxicities and survival in advanced hepatocellular carcinoma patients treated with sorafenib. Hepatol Res (2012) 0.97
Age-related fat deposition in multifidus muscle could be a marker for nonalcoholic fatty liver disease. J Gastroenterol (2009) 0.96
Biochemical evidence supporting the presence of the classical mevalonate pathway in the thermoacidophilic archaeon Sulfolobus solfataricus. J Biochem (2013) 0.95
Radiofrequency ablation with the real-time virtual sonography system for treating hepatocellular carcinoma difficult to detect by ultrasonography. J Clin Biochem Nutr (2007) 0.95
Covalent modification of reduced flavin mononucleotide in type-2 isopentenyl diphosphate isomerase by active-site-directed inhibitors. Proc Natl Acad Sci U S A (2011) 0.94
A novel zinc-dependent D-serine dehydratase from Saccharomyces cerevisiae. Biochem J (2008) 0.94
The implication of YggT of Escherichia coli in osmotic regulation. Biosci Biotechnol Biochem (2009) 0.94
Endoscopic hemostasis for bleeding gastric varices treated by combination of variceal ligation and sclerotherapy with N-butyl-2-cyanoacrylate. J Gastroenterol (2007) 0.93
Peginterferon alpha-2a (40 KD) plus ribavirin for the treatment of chronic hepatitis C in Japanese patients. J Gastroenterol Hepatol (2007) 0.93
Subcellular localization of a germiantion-specific cortex-lytic enzyme, SleB, of Bacilli during sporulation. Genes Genet Syst (2006) 0.93
Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus. FEBS J (2007) 0.93
PSK-mediated NF-kappaB inhibition augments docetaxel-induced apoptosis in human pancreatic cancer cells NOR-P1. Oncogene (2003) 0.93
Intertwined interspecies relationships: approaches to untangle the microbial network. Environ Microbiol (2009) 0.92
A case of primary leiomyoma of the liver in a patient without evidence of immunosuppression. Hepatol Res (2002) 0.92
Hepatocyte growth factor induces collagenase (matrix metalloproteinase-1) via the transcription factor Ets-1 in human hepatic stellate cell line. J Hepatol (2002) 0.90
Restricted neural epidermal growth factor-like like 2 (NELL2) expression during muscle and neuronal differentiation. Mech Dev (2002) 0.90
Gene therapy for human alpha1-antitrypsin deficiency in an animal model using SV40-derived vectors. Gastroenterology (2004) 0.89
Induction of multiple matrix metalloproteinase genes in human hepatocellular carcinoma by hepatocyte growth factor via a transcription factor Ets-1. Hepatol Res (2003) 0.89
Case-control study on cigarette smoking and the risk of hepatocellular carcinoma among Japanese. Cancer Sci (2007) 0.89
Virological response in patients with hepatitis C virus genotype 1b and a high viral load: impact of peginterferon-alpha-2a plus ribavirin dose reductions and host-related factors. Clin Drug Investig (2008) 0.89
A case of unclassified multicystic biliary tumor with biliary adenofibroma features. Pathol Int (2012) 0.88
Effects of medicinal mushroom (Sparassis crispa) on wound healing in streptozotocin-induced diabetic rats. Am J Surg (2008) 0.88
Body mass index is associated with age-at-onset of HCV-infected hepatocellular carcinoma patients. World J Gastroenterol (2011) 0.88
Expression of germination-related enzymes, CspA, CspB, CspC, SleC, and SleM, of Clostridium perfringens S40 in the mother cell compartment of sporulating cells. Genes Genet Syst (2006) 0.88
Hepatitis C virus infection enhances insulin resistance induced by visceral fat accumulation. Liver Int (2008) 0.88
Antifibrotic effects of hepatocyte growth factor on scleroderma fibroblasts and analysis of its mechanism. Mod Rheumatol (2006) 0.87
Nutritional status and quality of life in current patients with liver cirrhosis as assessed in 2007-2011. Hepatol Res (2013) 0.87
Downregulation of programmed cell death 4 (PDCD4) in tumorigenesis and progression of human digestive tract cancers. Tumour Biol (2013) 0.87
Hsc62, Hsc56, and GrpE, the third Hsp70 chaperone system of Escherichia coli. Biochem Biophys Res Commun (2002) 0.87
Influence of alcohol consumption and gene polymorphisms of ADH2 and ALDH2 on hepatocellular carcinoma in a Japanese population. Int J Cancer (2006) 0.87
Specific partial reduction of geranylgeranyl diphosphate by an enzyme from the thermoacidophilic archaeon Sulfolobus acidocaldarius yields a reactive prenyl donor, not a dead-end product. J Bacteriol (2008) 0.87
Correlations between trait anxiety, personality and fatigue: study based on the Temperament and Character Inventory. J Psychosom Res (2003) 0.86
Crystal structure of a homolog of mammalian serine racemase from Schizosaccharomyces pombe. J Biol Chem (2009) 0.86
The incidence of hepatocellular carcinoma associated with hepatitis C infection decreased in Kyushu area. Med Sci Monit (2011) 0.86
Eradication of hepatitis C virus by interferon improves whole-body insulin resistance and hyperinsulinaemia in patients with chronic hepatitis C. Liver Int (2009) 0.86
Cold-active DnaK of an Antarctic psychrotroph Shewanella sp. Ac10 supporting the growth of dnaK-null mutant of Escherichia coli at cold temperatures. Extremophiles (2004) 0.85