Published in Am J Physiol Lung Cell Mol Physiol on October 01, 2002
Esophageal and transpulmonary pressures in acute respiratory failure. Crit Care Med (2006) 3.62
Low-tidal-volume ventilation in the acute respiratory distress syndrome. N Engl J Med (2007) 3.60
Body mass index is independently associated with hospital mortality in mechanically ventilated adults with acute lung injury. Crit Care Med (2006) 3.38
Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretch. Am J Pathol (2006) 2.25
Brief, large tidal volume ventilation initiates lung injury and a systemic response in fetal sheep. Am J Respir Crit Care Med (2007) 1.73
In situ enhancement of pulmonary surfactant function using temporary flow reversal. J Appl Physiol (1985) (2011) 1.62
Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability. Am J Physiol Lung Cell Mol Physiol (2010) 1.46
Cytokine release following recruitment maneuvers. Chest (2007) 1.45
Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury. PLoS One (2008) 1.41
Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins. Antioxid Redox Signal (2009) 1.36
Magnitude-dependent effects of cyclic stretch on HGF- and VEGF-induced pulmonary endothelial remodeling and barrier regulation. Am J Physiol Lung Cell Mol Physiol (2008) 1.22
Conditional deletion of Nrf2 in airway epithelium exacerbates acute lung injury and impairs the resolution of inflammation. Am J Respir Cell Mol Biol (2011) 1.19
The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice. Am J Respir Crit Care Med (2009) 1.05
The 2-pore domain potassium channel TREK-1 regulates stretch-induced detachment of alveolar epithelial cells. PLoS One (2014) 1.03
Three-dimensional characterization of regional lung deformation. J Biomech (2011) 1.02
EGFR-activated signaling and actin remodeling regulate cyclic stretch-induced NRF2-ARE activation. Am J Respir Cell Mol Biol (2006) 1.02
Lung endothelial barrier protection by iloprost in the 2-hit models of ventilator-induced lung injury (VILI) involves inhibition of Rho signaling. Transl Res (2010) 1.00
Preexposure to hyperoxia causes increased lung injury and epithelial apoptosis in mice ventilated with high tidal volumes. Am J Physiol Lung Cell Mol Physiol (2010) 1.00
Afadin controls p120-catenin-ZO-1 interactions leading to endothelial barrier enhancement by oxidized phospholipids. J Cell Physiol (2012) 0.97
Toll-like receptor 4-myeloid differentiation factor 88 signaling contributes to ventilator-induced lung injury in mice. Anesthesiology (2010) 0.96
Bench-to-bedside review: Biotrauma and modulation of the innate immune response. Crit Care (2005) 0.94
Hyperoxia alters the mechanical properties of alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol (2012) 0.90
PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice. PLoS One (2015) 0.89
Lagrangian transport properties of pulmonary interfacial flows. J Fluid Mech (2011) 0.88
Lung and 'end organ' injury due to mechanical ventilation in animals: comparison between the prone and supine positions. Crit Care (2006) 0.87
Reciprocal backcross mice confirm major loci linked to hyperoxic acute lung injury survival time. Physiol Genomics (2009) 0.86
Linking the development of ventilator-induced injury to mechanical function in the lung. Ann Biomed Eng (2012) 0.85
Mechanical forces stimulate endothelial microparticle generation via caspase-dependent apoptosis-independent mechanism. Pulm Circ (2013) 0.85
Goal-directed mechanical ventilation: are we aiming at the right goals? A proposal for an alternative approach aiming at optimal lung compliance, guided by esophageal pressure in acute respiratory failure. Crit Care Res Pract (2012) 0.79
Cecal ligation and puncture accelerates development of ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol (2014) 0.78
Effects of transglutaminase 2 inhibition on ventilator-induced lung injury. J Korean Med Sci (2014) 0.78
Variable Ventilation as a Diagnostic Tool for the Injured Lung. IEEE Trans Biomed Eng (2014) 0.76
Elastin Cables Define the Axial Connective Tissue System in the Murine Lung. Anat Rec (Hoboken) (2015) 0.76
Computational Models of Ventilator Induced Lung Injury and Surfactant Dysfunction. Drug Discov Today Dis Models (2014) 0.75
Superoxide mediates tight junction complex dissociation in cyclically stretched lung slices. J Biomech (2015) 0.75
Predicting ventilator-induced lung injury using a lung injury cost function. J Appl Physiol (1985) (2016) 0.75
Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch. PLoS One (2016) 0.75
Modeling the Progression of Epithelial Leak Caused by Overdistension. Cell Mol Bioeng (2016) 0.75
The acute respiratory distress syndrome. J Clin Invest (2012) 5.61
The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies. J Am Coll Cardiol (2011) 4.57
Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury. Nat Med (2012) 3.47
Clinical risk factors for primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med (2013) 3.38
Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med (2006) 3.38
Association between cell-free hemoglobin, acetaminophen, and mortality in patients with sepsis: an observational study. Crit Care Med (2013) 3.30
Transfusion-related acute lung injury: incidence and risk factors. Blood (2011) 3.12
Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2003) 3.02
Postobstructive pulmonary edema: a case for hydrostatic mechanisms. Chest (2007) 2.97
Inflammasome-regulated cytokines are critical mediators of acute lung injury. Am J Respir Crit Care Med (2012) 2.92
Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med (2015) 2.80
Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med (2007) 2.79
Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults. J Am Soc Nephrol (2009) 2.77
Atrial Fibrillation Is an Independent Predictor of Mortality in Critically Ill Patients. Crit Care Med (2015) 2.77
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med (2006) 2.63
Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury. Am J Respir Crit Care Med (2006) 2.61
Comparison of the SpO2/FIO2 ratio and the PaO2/FIO2 ratio in patients with acute lung injury or ARDS. Chest (2007) 2.58
Plasma levels of receptor for advanced glycation end products, blood transfusion, and risk of primary graft dysfunction. Am J Respir Crit Care Med (2009) 2.43
Prioritizing the organization and management of intensive care services in the United States: the PrOMIS Conference. Crit Care Med (2007) 2.42
Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2011) 2.42
Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome. Crit Care Med (2011) 2.40
Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection. Am J Physiol Lung Cell Mol Physiol (2008) 2.39
Biological markers of acute kidney injury. J Am Soc Nephrol (2011) 2.36
Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol (2002) 2.30
Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med (2010) 2.28
Informed consent in research to improve the number and quality of deceased donor organs. Crit Care Med (2011) 2.18
Management of the critically ill patient with severe acute pancreatitis. Crit Care Med (2004) 2.16
Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol (2004) 2.15
Obesity and primary graft dysfunction after lung transplantation: the Lung Transplant Outcomes Group Obesity Study. Am J Respir Crit Care Med (2011) 2.11
Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome. Crit Care Med (2016) 2.08
Procoagulant alveolar microparticles in the lungs of patients with acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol (2009) 2.03
Clara cell protein (CC16), a marker of lung epithelial injury, is decreased in plasma and pulmonary edema fluid from patients with acute lung injury. Chest (2009) 2.02
Derivation and validation of Spo2/Fio2 ratio to impute for Pao2/Fio2 ratio in the respiratory component of the Sequential Organ Failure Assessment score. Crit Care Med (2009) 2.02
Early elevation of plasma soluble intercellular adhesion molecule-1 in pediatric acute lung injury identifies patients at increased risk of death and prolonged mechanical ventilation. Pediatr Crit Care Med (2003) 1.98
Prognostic value of surfactant proteins A and D in patients with acute lung injury. Crit Care Med (2003) 1.96
Early elevation of plasma von Willebrand factor antigen in pediatric acute lung injury is associated with an increased risk of death and prolonged mechanical ventilation. Pediatr Crit Care Med (2007) 1.92
Clinical trial of safety and efficacy of INH-A21 for the prevention of nosocomial staphylococcal bloodstream infection in premature infants. J Pediatr (2007) 1.89
Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients. Crit Care Med (2011) 1.86
Construct validity of the definition of primary graft dysfunction after lung transplantation. J Heart Lung Transplant (2010) 1.85
Stimulation of alveolar epithelial fluid clearance in human lungs by exogenous epinephrine. Crit Care Med (2006) 1.81
Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation. Chest (2013) 1.79
The association between BMI and plasma cytokine levels in patients with acute lung injury. Chest (2010) 1.75
Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. Crit Care Med (2007) 1.73
One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. Intensive Care Med (2014) 1.70
Acute effects of tidal volume strategy on hemodynamics, fluid balance, and sedation in acute lung injury. Crit Care Med (2005) 1.70
Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury. Crit Care (2008) 1.69
Variation in PTX3 is associated with primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med (2012) 1.66
Elevated urinary IL-18 levels at the time of ICU admission predict adverse clinical outcomes. Clin J Am Soc Nephrol (2010) 1.64
Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells. Blood (2008) 1.63
ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio. Am J Respir Crit Care Med (2011) 1.62
Distinct injury markers for the early detection and prognosis of incident acute kidney injury in critically ill adults with preserved kidney function. Kidney Int (2013) 1.62
Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury. Intensive Care Med (2008) 1.61
Plasma interleukin-8 is not an effective risk stratification tool for adults with vasopressor-dependent septic shock. Crit Care Med (2010) 1.60
Association of protein C and type 1 plasminogen activator inhibitor with primary graft dysfunction. Am J Respir Crit Care Med (2006) 1.57
Heterogeneous phenotypes of acute respiratory distress syndrome after major trauma. Ann Am Thorac Soc (2014) 1.57
Acute lung injury edema fluid decreases net fluid transport across human alveolar epithelial type II cells. J Biol Chem (2007) 1.56
Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction. Am J Respir Crit Care Med (2014) 1.51
Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis. J Trauma (2010) 1.51
Case of fulminant hepatic failure due to unrecognized peripartum cardiomyopathy. Crit Care Med (2005) 1.49
Body composition and mortality after adult lung transplantation in the United States. Am J Respir Crit Care Med (2014) 1.49
Challenges in translating plasma proteomics from bench to bedside: update from the NHLBI Clinical Proteomics Programs. Am J Physiol Lung Cell Mol Physiol (2008) 1.46
Sympathetic nerve-dependent regulation of mucosal vascular tone modifies airway smooth muscle reactivity. J Appl Physiol (1985) (2010) 1.43
Pulmonary edema fluid from patients with early lung injury stimulates fibroblast proliferation through IL-1 beta-induced IL-6 expression. J Immunol (2004) 1.41
The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor. Thorax (2007) 1.41
Report of the ISHLT Working Group on Primary Lung Graft Dysfunction part V: predictors and outcomes. J Heart Lung Transplant (2005) 1.39
MCP-1 gene activation marks acute kidney injury. J Am Soc Nephrol (2010) 1.34
Ratio of angiopoietin-2 to angiopoietin-1 as a predictor of mortality in acute lung injury patients. Crit Care Med (2010) 1.32
Systemic microvascular leak in an in vivo rat model of ventilator-induced lung injury. Am J Respir Crit Care Med (2003) 1.32
Activation of TNFR1 ectodomain shedding by mitochondrial Ca2+ determines the severity of inflammation in mouse lung microvessels. J Clin Invest (2011) 1.32
Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies. Chest (2015) 1.31
Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury. Crit Care Med (2011) 1.31
Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation. Am J Respir Cell Mol Biol (2006) 1.29
Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome. Crit Care (2013) 1.26
Aerosolized beta(2)-adrenergic agonists achieve therapeutic levels in the pulmonary edema fluid of ventilated patients with acute respiratory failure. Intensive Care Med (2002) 1.18
Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol (2004) 1.18
Plasma protein C levels in patients with acute lung injury: prognostic significance. Crit Care Med (2004) 1.13
Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma. PLoS One (2012) 1.11
Prostaglandin E2 mediates IL-1beta-related fibroblast mitogenic effects in acute lung injury through differential utilization of prostanoid receptors. J Immunol (2008) 1.11
Soluble p-selectin and the risk of primary graft dysfunction after lung transplantation. Chest (2009) 1.10
Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome. Crit Care Med (2015) 1.10
Randomized, placebo-controlled trial of acetaminophen for the reduction of oxidative injury in severe sepsis: the Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis trial. Crit Care Med (2015) 1.10
Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol (2002) 1.09
Association between haptoglobin, hemopexin and mortality in adults with sepsis. Crit Care (2013) 1.09
Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4. Mol Cancer (2011) 1.08
Keratinocyte growth factor can enhance alveolar epithelial repair by nonmitogenic mechanisms. Am J Physiol Lung Cell Mol Physiol (2002) 1.07
Can nicotine treat sepsis? Nat Med (2004) 1.05
Accuracy and reproducibility of a multiplex immunoassay platform: a validation study. J Immunol Methods (2011) 1.05
Is there still a role for the lung injury score in the era of the Berlin definition ARDS? Ann Intensive Care (2014) 1.04
Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease. Am J Respir Crit Care Med (2015) 1.04
Associations of markers of inflammation and coagulation with delirium during critical illness. Intensive Care Med (2012) 1.02
Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2006) 1.01
Intra-alveolar tissue factor pathway inhibitor is not sufficient to block tissue factor procoagulant activity. Am J Physiol Lung Cell Mol Physiol (2008) 1.00
High-molecular-weight hyaluronan--a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats. Crit Care (2008) 1.00
Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells. Biochem Pharmacol (2010) 1.00
The role of the coagulation cascade in the continuum of sepsis and acute lung injury and acute respiratory distress syndrome. Semin Respir Crit Care Med (2006) 1.00
Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress. Thorax (2012) 0.99
Epidemiology of critical care syndromes, organ failures, and life-support interventions in a suburban US community. Chest (2011) 0.99
Annexin-1 regulates growth arrest induced by high levels of estrogen in MCF-7 breast cancer cells. Mol Cancer Res (2009) 0.98
An official multi-society statement: the role of clinical research results in the practice of critical care medicine. Am J Respir Crit Care Med (2012) 0.97
Prehospital aspirin use is associated with reduced risk of acute respiratory distress syndrome in critically ill patients: a propensity-adjusted analysis. Crit Care Med (2015) 0.97