Published in Proc Natl Acad Sci U S A on September 18, 2002
The myosin-binding protein C motif binds to F-actin in a phosphorylation-sensitive manner. J Biol Chem (2009) 2.16
De novo high-resolution protein structure determination from sparse spin-labeling EPR data. Structure (2008) 1.84
RosettaEPR: an integrated tool for protein structure determination from sparse EPR data. J Struct Biol (2010) 1.50
Interaction of cardiac troponin with cardiotonic drugs: a structural perspective. Biochem Biophys Res Commun (2007) 1.01
The structure of the inter-SH2 domain of class IA phosphoinositide 3-kinase determined by site-directed spin labeling EPR and homology modeling. Proc Natl Acad Sci U S A (2003) 1.01
Global structure of a three-way junction in a phi29 packaging RNA dimer determined using site-directed spin labeling. J Am Chem Soc (2012) 0.98
Conformational changes at the tetramerization site of erythroid alpha-spectrin upon binding beta-spectrin: a spin label EPR study. Biochemistry (2008) 0.95
Troponin regulatory function and dynamics revealed by H/D exchange-mass spectrometry. J Biol Chem (2009) 0.92
Optimal bundling of transmembrane helices using sparse distance constraints. Protein Sci (2004) 0.86
Ca(2+)-regulatory function of the inhibitory peptide region of cardiac troponin I is aided by the C-terminus of cardiac troponin T: Effects of familial hypertrophic cardiomyopathy mutations cTnI R145G and cTnT R278C, alone and in combination, on filament sliding. Arch Biochem Biophys (2014) 0.84
Switch action of troponin on muscle thin filament as revealed by spin labeling and pulsed EPR. J Biol Chem (2010) 0.82
Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility. Arch Biochem Biophys (2016) 0.82
Interdomain orientation of cardiac troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact state. Protein Sci (2012) 0.82
Low temperature dynamic mapping reveals unexpected order and disorder in troponin. J Biol Chem (2010) 0.80
Ca2+-induced PRE-NMR changes in the troponin complex reveal the possessive nature of the cardiac isoform for its regulatory switch. PLoS One (2014) 0.80
Probing protein-peptide binding surfaces using charged stable free radicals and transverse paramagnetic relaxation enhancement (PRE). J Biomol NMR (2005) 0.79
pH-responsive titratable inotropic performance of histidine-modified cardiac troponin I. Biophys J (2012) 0.78
Dual regulatory functions of the thin filament revealed by replacement of the troponin I inhibitory peptide with a linker. J Biol Chem (2010) 0.77
Applications of electron paramagnetic resonance to studies of neurological disease. Eur Biophys J (2008) 0.77
Distance and dynamics determination by W-band DEER and W-band ST-EPR. Eur Biophys J (2009) 0.76
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins (1991) 36.69
Regulation of contraction in striated muscle. Physiol Rev (2000) 9.40
Motion of spin-labeled side chains in T4 lysozyme. Correlation with protein structure and dynamics. Biochemistry (1996) 5.52
Dead-time free measurement of dipole-dipole interactions between electron spins. J Magn Reson (2000) 5.26
Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy. Nat Struct Biol (1998) 4.76
A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin. Proc Natl Acad Sci U S A (1994) 4.27
Recent advances in site-directed spin labeling of proteins. Curr Opin Struct Biol (1998) 3.94
Determination of the distance between two spin labels attached to a macromolecule. Proc Natl Acad Sci U S A (1995) 3.44
Structure of the calcium regulatory muscle protein troponin-C at 2.8 A resolution. Nature (1985) 2.65
Preparation of troponin and its subunits. Methods Enzymol (1982) 2.34
The relationship between biological activity and primary structure of troponin I from white skeletal muscle of the rabbit. Biochem J (1976) 1.84
Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2-A resolution. J Biol Chem (1988) 1.76
Molecular structure of troponin C from chicken skeletal muscle at 3-angstrom resolution. Science (1985) 1.66
Calcium regulation of skeletal muscle thin filament motility in vitro. Biophys J (1997) 1.64
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain. J Biol Chem (1997) 1.61
Troponin and its interactions with tropomyosin. An electron microscope study. J Mol Biol (1982) 1.48
Structure of co-crystals of tropomyosin and troponin. Nature (1987) 1.47
Conformation of the regulatory domain of cardiac muscle troponin C in its complex with cardiac troponin I. J Biol Chem (1999) 1.43
Molecular mechanism of troponin-C function. J Muscle Res Cell Motil (1992) 1.42
Structural and regulatory functions of the NH2- and COOH-terminal regions of skeletal muscle troponin I. J Biol Chem (1994) 1.32
Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution. Proc Natl Acad Sci U S A (1998) 1.31
Structural determination of spin label immobilization and orientation: a Monte Carlo minimization approach. J Magn Reson (2002) 1.25
Troponin organization on relaxed and activated thin filaments revealed by electron microscopy and three-dimensional reconstruction. J Mol Biol (2001) 1.23
Ca(2+)-induced switching of troponin and tropomyosin on actin filaments as revealed by electron cryo-microscopy. J Mol Biol (2001) 1.15
Calcium-induced movement of troponin-I relative to actin in skeletal muscle thin filaments. Science (1990) 1.14
Direct measurement of small ligand-induced conformational changes in the aspartate chemoreceptor using EPR. Biochemistry (1998) 1.09
Ca(2+) induces an extended conformation of the inhibitory region of troponin I in cardiac muscle troponin. J Mol Biol (2001) 1.05
Inhibitory region of troponin I: Ca(2+)-dependent structural and environmental changes in the troponin-tropomyosin complex and in reconstituted thin filaments. Biochemistry (2000) 1.02
Conformation of the N-terminal segment of a monocysteine mutant of troponin I from cardiac muscle. Biochemistry (1997) 1.00
Structure of the troponin complex. Implications of photocross-linking of troponin I to troponin C thiol mutants. J Biol Chem (1994) 0.97
The effect of regulatory Ca2+ on the in situ structures of troponin C and troponin I: a neutron scattering study. J Mol Biol (1998) 0.95
Molecular cloning of human cardiac troponin I using polymerase chain reaction. FEBS Lett (1990) 0.93
Disparate fluorescence properties of 2-[4'-(iodoacetamido)anilino]-naphthalene-6-sulfonic acid attached to Cys-84 and Cys-35 of troponin C in cardiac muscle troponin. Biophys J (1997) 0.92
Modulation of cardiac troponin C-cardiac troponin I regulatory interactions by the amino-terminus of cardiac troponin I. Biochemistry (2001) 0.91
Identification and mutagenesis of a highly conserved domain in troponin T responsible for troponin I binding: potential role for coiled coil interaction. Proc Natl Acad Sci U S A (1998) 0.90
A synthetic peptide mimics troponin I function in the calcium-dependent regulation of muscle contraction. FEBS Lett (1993) 0.89
The interaction of rabbit skeletal muscle troponin-T fragments with troponin-I. Can J Biochem Cell Biol (1985) 0.88
Calcium binding to the regulatory domain of skeletal muscle troponin C induces a highly constrained open conformation. J Mol Biol (1998) 0.87
Proximity relationships between residue 117 of rabbit skeletal troponin-I and residues in troponin-C and actin. Biophys J (2001) 0.87
A model of troponin-I in complex with troponin-C using hybrid experimental data: the inhibitory region is a beta-hairpin. Protein Sci (2000) 0.85
Orientational changes of troponin C associated with thin filament activation. Biochemistry (1994) 0.85
Residues 48 and 82 at the N-terminal hydrophobic pocket of rabbit skeletal muscle troponin-C photo-cross-link to Met121 of troponin-I. Biochemistry (1999) 0.83
Tryptophan mutants of troponin C from skeletal muscle--an optical probe of the regulatory domain. Eur J Biochem (1998) 0.83
Cross-linking of rabbit skeletal muscle troponin with the photoactive reagent 4-maleimidobenzophenone: identification of residues in troponin I that are close to cysteine-98 of troponin C. Biochemistry (1987) 0.82
Cardiac troponin I inhibitory peptide: location of interaction sites on troponin C. FEBS Lett (2000) 0.82
Calcium-induced flexibility changes in the troponin C-troponin I complex. Biochim Biophys Acta (2000) 0.78
Troponin I inhibitory peptide (96-115) has an extended conformation when bound to skeletal muscle troponin C. Biochemistry (1999) 0.78
Transmission of the Ca2+-regulatory signal in skeletal muscle thin filaments. Adv Exp Med Biol (1988) 0.78
Conformational changes induced in troponin I by interaction with troponin T and actin/tropomyosin. Biochim Biophys Acta (1999) 0.77
Molecular cloning and expression of chicken cardiac troponin C. Circ Res (1989) 0.77
Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis. PLoS Biol (2010) 5.39
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane. Immunity (2008) 3.01
Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice. ISME J (2009) 2.69
Cerebrospinal fluid pressure in glaucoma: a prospective study. Ophthalmology (2009) 2.60
Congruency in homonymous hemianopia. Am J Ophthalmol (2007) 2.17
Valsalva manoeuver, intra-ocular pressure, cerebrospinal fluid pressure, optic disc topography: Beijing intracranial and intra-ocular pressure study. Acta Ophthalmol (2013) 2.09
Different characteristics of nonthymomatous generalized myasthenia gravis with and without oropharyngeal involvement. Ann Thorac Surg (2007) 2.01
Myosin cleft movement and its coupling to actomyosin dissociation. Nat Struct Biol (2003) 1.80
Explicit treatment of spin labels in modeling of distance constraints from dipolar EPR and DEER. J Am Chem Soc (2005) 1.72
Cerebrospinal fluid pressure in ocular hypertension. Acta Ophthalmol (2011) 1.59
Central retinal artery occlusion and recurrent papillitis in a patient with incomplete Behçet disease. J Neuroophthalmol (2011) 1.40
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization. Nat Struct Mol Biol (2011) 1.29
Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity. J Virol (2009) 1.27
A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome. FEMS Microbiol Ecol (2013) 1.25
Protein dynamics and monomer-monomer interactions in AntR activation by electron paramagnetic resonance and double electron-electron resonance. Biochemistry (2007) 1.23
Rotational dynamics of phospholamban determined by multifrequency electron paramagnetic resonance. Biophys J (2007) 1.20
Solution structure of the cytoplasmic domain of erythrocyte membrane band 3 determined by site-directed spin labeling. Biochemistry (2005) 1.18
Noninvasive intracranial pressure estimation by orbital subarachnoid space measurement: the Beijing Intracranial and Intraocular Pressure (iCOP) study. Crit Care (2013) 1.17
Transcriptome analysis on Chinese shrimp Fenneropenaeus chinensis during WSSV acute infection. PLoS One (2013) 1.14
Inheritance and mapping of powdery mildew resistance gene Pm43 introgressed from Thinopyrum intermedium into wheat. Theor Appl Genet (2009) 1.14
Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion. Nucleic Acids Res (2013) 1.11
Inhibition of alpha interferon (IFN-α)-induced microRNA-122 negatively affects the anti-hepatitis B virus efficiency of IFN-α. J Virol (2012) 1.10
Mapping electron paramagnetic resonance spin label conformations by the simulated scaling method. J Am Chem Soc (2007) 1.09
Synergistic angiogenesis promoting effects of extracellular matrix scaffolds and adipose-derived stem cells during wound repair. Tissue Eng Part A (2010) 1.07
Cerebrospinal fluid pressure correlated with body mass index. Graefes Arch Clin Exp Ophthalmol (2011) 1.07
Trans-lamina cribrosa pressure difference correlated with neuroretinal rim area in glaucoma. Graefes Arch Clin Exp Ophthalmol (2011) 1.07
Discovery of the genes in response to white spot syndrome virus (WSSV) infection in Fenneropenaeus chinensis through cDNA microarray. Mar Biotechnol (NY) (2006) 1.04
Treg suppress CTL responses upon immunization with HSP gp96. Eur J Immunol (2009) 1.04
In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor. Prostaglandins Other Lipid Mediat (2013) 1.01
Putative Thinopyrum intermedium-derived stripe rust resistance gene Yr50 maps on wheat chromosome arm 4BL. Theor Appl Genet (2012) 1.01
MicroRNA-146a feedback suppresses T cell immune function by targeting Stat1 in patients with chronic hepatitis B. J Immunol (2013) 1.00
Magnetic chitosan nanocomposites: a useful recyclable tool for heavy metal ion removal. Langmuir (2009) 1.00
The use of dentin matrix scaffold and dental follicle cells for dentin regeneration. Biomaterials (2009) 1.00
Structure of the cytoplasmic domain of erythrocyte band 3 hereditary spherocytosis variant P327R: band 3 Tuscaloosa. Biochemistry (2007) 1.00
Solubilization and characterization of the anthrax toxin pore in detergent micelles. Protein Sci (2009) 1.00
Mn(II) binding by the anthracis repressor from Bacillus anthracis. Biochemistry (2006) 0.97
Electron spin resonance studies of trityl OX063 at a concentration optimal for DNP. Phys Chem Chem Phys (2013) 0.95
Thauera and Azoarcus as functionally important genera in a denitrifying quinoline-removal bioreactor as revealed by microbial community structure comparison. FEMS Microbiol Ecol (2006) 0.94
Construction and characterization of two bacterial artificial chromosome libraries of Zhikong scallop, Chlamys farreri Jones et Preston, and identification of BAC clones containing the genes involved in its innate immune system. Mar Biotechnol (NY) (2008) 0.94
Interactions of anthrax lethal factor with protective antigen defined by site-directed spin labeling. Proc Natl Acad Sci U S A (2011) 0.94
Effects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibrium between closed and open conformations of the regulatory N-domain of isolated cardiac troponin C. Biochemistry (2013) 0.93
Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry. J Biol Chem (2013) 0.93
The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy. RSC Adv (2012) 0.93
Protective effect of tetrahydroxystilbene glucoside on 6-OHDA-induced apoptosis in PC12 cells through the ROS-NO pathway. PLoS One (2011) 0.92
Protective effects of salidroside in the MPTP/MPP(+)-induced model of Parkinson's disease through ROS-NO-related mitochondrion pathway. Mol Neurobiol (2014) 0.92
Dissolution DNP-NMR spectroscopy using galvinoxyl as a polarizing agent. J Magn Reson (2012) 0.91
Tissue engineering of cementum/periodontal-ligament complex using a novel three-dimensional pellet cultivation system for human periodontal ligament stem cells. Tissue Eng Part C Methods (2009) 0.91
Effect of age and extrinsic microenvironment on the proliferation and osteogenic differentiation of rat dental pulp stem cells in vitro. J Endod (2009) 0.90
Eccentric contractions do not induce rhabdomyolysis in malignant hyperthermia susceptible mice. J Appl Physiol (1985) (2008) 0.90
Neuromyelitis optica antibodies in patients with severe optic neuritis in China. J Neuroophthalmol (2011) 0.90
A comparative physical map reveals the pattern of chromosomal evolution between the turkey (Meleagris gallopavo) and chicken (Gallus gallus) genomes. BMC Genomics (2011) 0.89
Experimental study of nano-HA artificial bone with different pore sizes for repairing the radial defect. Int Orthop (2008) 0.89
Chromosomal localization and molecular marker development of the lipopolysaccharide and beta-1,3-glucan binding protein gene in the Zhikong scallop Chlamys farreri (Jones et Preston) (Pectinoida, Pectinidae). Genet Mol Biol (2010) 0.88
The chemistry of phospholipid binding by the Saccharomyces cerevisiae phosphatidylinositol transfer protein Sec14p as determined by EPR spectroscopy. J Biol Chem (2006) 0.88
Molecular characteristics and expression analysis of calreticulin in Chinese shrimp Fenneropenaeus chinensis. Comp Biochem Physiol B Biochem Mol Biol (2007) 0.88
Dynamics of tropomyosin in muscle fibers as monitored by saturation transfer EPR of bi-functional probe. PLoS One (2011) 0.87
Combination treatment with anti-CD20 and oral anti-CD3 prevents and reverses autoimmune diabetes. Diabetes (2013) 0.86
The synergistic therapeutic effect of hepatocyte growth factor and granulocyte colony-stimulating factor on pulmonary hypertension in rats. Heart Vessels (2013) 0.86
The inhibitory effect of tongxieyaofang on rats with post infectious irritable bowel syndrome through regulating colonic par-2 receptor. BMC Complement Altern Med (2013) 0.85
Broad disorder and the allosteric mechanism of myosin II regulation by phosphorylation. Proc Natl Acad Sci U S A (2011) 0.85
Myosin regulatory domain orientation in skeletal muscle fibers: application of novel electron paramagnetic resonance spectral decomposition and molecular modeling methods. Biophys J (2004) 0.85
Monitoring the microbial community during solid-state acetic acid fermentation of Zhenjiang aromatic vinegar. Food Microbiol (2011) 0.85
Experimental study of nano-hydroxyapatite/recombinant human bone morphogenetic protein-2 composite artificial bone. Artif Cells Blood Substit Immobil Biotechnol (2010) 0.84
The mosaic accessory gene structures of the SXT/R391-like integrative and conjugative elements derived from Vibrio spp. isolated from aquatic products and environment in the Yangtze River Estuary, China. BMC Microbiol (2013) 0.84
Silver oxide nanowalls grown on Cu substrate as an enzymeless glucose sensor. ACS Appl Mater Interfaces (2009) 0.84
Cross-linked collagen-chondroitin sulfate-hyaluronic acid imitating extracellular matrix as scaffold for dermal tissue engineering. Tissue Eng Part C Methods (2010) 0.84
Genome physical mapping of polyploids: a BIBAC physical map of cultivated tetraploid cotton, Gossypium hirsutum L. PLoS One (2012) 0.83
Transcriptomics and proteomics in the study of H1N1 2009. Genomics Proteomics Bioinformatics (2010) 0.83
FKBP12 deficiency reduces strength deficits after eccentric contraction-induced muscle injury. J Appl Physiol (1985) (2008) 0.83
Heat shock protein gp96 enhances humoral and T cell responses, decreases Treg frequency and potentiates the anti-HBV activity in BALB/c and transgenic mice. Vaccine (2011) 0.83
Reversing multidrug resistance by intracellular delivery of Pluronic® P85 unimers. Biomaterials (2013) 0.83
cDNA cloning, characterization and expression analysis of the antioxidant enzyme gene, catalase, of Chinese shrimp Fenneropenaeus chinensis. Fish Shellfish Immunol (2008) 0.83
Proteomic profiling of the insoluble pellets of the transected rat spinal cord. J Neurotrauma (2009) 0.83
What is the maximum duration to perform the hemorheological measurement for the human and mammals. Clin Hemorheol Microcirc (2004) 0.83
Alpha-1 antitrypsin variants in plasma from HIV-infected patients revealed by proteomic and glycoproteomic analysis. Electrophoresis (2010) 0.83
Intraocular pressure vs intracranial pressure in disease conditions: a prospective cohort study (Beijing iCOP study). BMC Neurol (2012) 0.82
Host proteome research in HIV infection. Genomics Proteomics Bioinformatics (2010) 0.82
Regulatory T-cell depletion synergizes with gp96-mediated cellular responses and antitumor activity. Cancer Immunol Immunother (2011) 0.82
Increased expression of Gp96 by HBx-induced NF-κB activation feedback enhances hepatitis B virus production. PLoS One (2013) 0.82
Co-metabolic biodegradation of DBP by Paenibacillus sp. S-3 and H-2. Curr Microbiol (2014) 0.82
Assessment of the green florescence protein labeling method for tracking implanted mesenchymal stem cells. Cytotechnology (2012) 0.82
Advantages of isotopic depletion of proteins for hydrogen/deuterium exchange experiments monitored by mass spectrometry. Anal Chem (2010) 0.82
Interdomain orientation of cardiac troponin C characterized by paramagnetic relaxation enhancement NMR reveals a compact state. Protein Sci (2012) 0.82
Clinical characteristics, therapeutic outcomes of isolated atypical optic neuritis in China. J Neurol Sci (2011) 0.81
Pediatric homonymous hemianopia. J AAPOS (2006) 0.81
Cloning, expression and identification of ferritin from Chinese shrimp, Fenneropenaeus chinensis. J Biotechnol (2006) 0.81
The role of Gr1+ cells after anti-CD20 treatment in type 1 diabetes in nonobese diabetic mice. J Immunol (2011) 0.81
Correlation of circulating glucocorticoid-induced TNFR-related protein ligand levels with disease activity in patients with systemic lupus erythematosus. Clin Dev Immunol (2012) 0.80
Structural differentiation of bacterial communities in indole-degrading bioreactors under denitrifying and sulfate-reducing conditions. Res Microbiol (2010) 0.80
Regulatory and catalytic domain dynamics of smooth muscle myosin filaments. Biochemistry (2006) 0.80
Nonbenzamidine acylsulfonamide tissue factor-factor VIIa inhibitors. Bioorg Med Chem Lett (2013) 0.80
Fruit coloration and anthocyanin biosynthesis after bag removal in non-red and red apples (Malus × domestica Borkh.). Molecules (2013) 0.80
Dispersive liquid-liquid microextraction followed by reversed phase HPLC for the determination of decabrominated diphenyl ether in natural water. J Sep Sci (2008) 0.80
Intracranial pressure fluctuations: a potential risk factor for glaucoma? Acta Ophthalmol (2013) 0.79
Induction of regulatory T cells by high-dose gp96 suppresses murine liver immune hyperactivation. PLoS One (2013) 0.79
Nucleotide-induced flexibility change in neck linkers of dimeric kinesin as detected by distance Measurements using spin-labeling EPR. J Mol Biol (2009) 0.79
A folate receptor electrochemical sensor based on terminal protection and supersandwich DNAzyme amplification. Biosens Bioelectron (2012) 0.79
An ultrasensitive electrochemical method for detection of Ag(+) based on cyclic amplification of exonuclease III activity on cytosine-Ag(+)-cytosine. Analyst (2013) 0.79