Published in Chem Commun (Camb) on October 21, 2002
En bloc vascular resection for locally advanced pancreatic malignancies infiltrating major blood vessels: perioperative outcome and long-term survival in 136 patients. Ann Surg (2008) 2.64
Control of protein phosphorylation with a genetically encoded photocaged amino acid. Nat Chem Biol (2007) 1.99
Quantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain length. Nucleic Acids Res (2007) 1.73
Targeted next-generation sequencing by specific capture of multiple genomic loci using low-volume microfluidic DNA arrays. Anal Bioanal Chem (2008) 1.68
Frequent homogeneous HER-2 amplification in primary and metastatic adenocarcinoma of the esophagus. Mod Pathol (2006) 1.56
Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia. Blood (2004) 1.55
Site-specific PEGylation of proteins containing unnatural amino acids. Bioorg Med Chem Lett (2004) 1.43
KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry. Nat Chem Biol (2012) 1.24
Improved LNA probe-based assay for the detection of African and South American yellow fever virus strains. J Clin Virol (2010) 1.22
Novel strategies for the site-specific covalent labelling of nucleic acids. Chem Commun (Camb) (2008) 1.18
Replication through an abasic DNA lesion: structural basis for adenine selectivity. EMBO J (2010) 1.16
Structural insights into DNA replication without hydrogen bonds. J Am Chem Soc (2013) 1.15
RAD51 overexpression is a negative prognostic marker for colorectal adenocarcinoma. Int J Cancer (2012) 1.10
A genetically encoded diazirine photocrosslinker in Escherichia coli. Chembiochem (2007) 1.09
Synthesis of defined ubiquitin dimers. J Am Chem Soc (2010) 1.01
Site-specific labeling of proteins with NMR-active unnatural amino acids. J Biomol NMR (2009) 1.00
Activated leukocyte cell adhesion molecule (CD166)--its prognostic power for colorectal cancer patients. J Surg Res (2012) 0.97
A genetically encoded spin label for electron paramagnetic resonance distance measurements. J Am Chem Soc (2014) 0.96
Expression and prognostic relevance of MAGE-C1/CT7 and MAGE-C2/CT10 in osteolytic lesions of patients with multiple myeloma. Exp Mol Pathol (2010) 0.96
Prolonged intrathecal release of soluble Fas following severe traumatic brain injury in humans. J Neuroimmunol (2002) 0.92
Evolving a thermostable DNA polymerase that amplifies from highly damaged templates. Angew Chem Int Ed Engl (2007) 0.92
A molecular beacon for quantitative monitoring of the DNA polymerase reaction in real-time. Angew Chem Int Ed Engl (2002) 0.92
Implications of active site constraints on varied DNA polymerase selectivity. J Am Chem Soc (2002) 0.92
Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design. Angew Chem Int Ed Engl (2005) 0.91
New light-sensitive nucleosides for caged DNA strand breaks. Chembiochem (2002) 0.90
DNA-templated synthesis: more versatile than expected. Angew Chem Int Ed Engl (2002) 0.90
Opposed steric constraints in human DNA polymerase beta and E. coli DNA polymerase I. J Am Chem Soc (2008) 0.89
A nucleoside triphosphate for site-specific labelling of DNA by the Staudinger ligation. Chem Commun (Camb) (2007) 0.89
The genetic incorporation of a distance probe into proteins in Escherichia coli. J Am Chem Soc (2006) 0.89
Evaluation of the stereotactic 8G vacuum-assisted breast biopsy in the histologic evaluation of suspicious mammography findings (BI-RADS IV). Invest Radiol (2005) 0.89
Generation of a mono-ubiquitinated PCNA mimic by click chemistry. Chembiochem (2011) 0.88
A DNA polymerase with increased reactivity for ribonucleotides and C5-modified deoxyribonucleotides. Chembiochem (2010) 0.87
Structures of KOD and 9°N DNA polymerases complexed with primer template duplex. Chembiochem (2013) 0.87
Crossing the Rubicon: when pancreatic resection with curative intent ends in an R2 status. Impact of "desmoplastic pseudo-pancreatitis" and anatomical site of irresectability. Ann Surg Oncol (2009) 0.87
Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase. Proc Natl Acad Sci U S A (2010) 0.86
An efficient method for the construction of functionalized DNA bearing amino acid groups through cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR. Chemistry (2007) 0.86
GFAP-independent inflammatory competence and trophic functions of astrocytes generated from murine embryonic stem cells. Glia (2011) 0.86
Evolving thermostable reverse transcriptase activity in a DNA polymerase scaffold. Angew Chem Int Ed Engl (2006) 0.86
Rapid labeling of metabolically engineered cell-surface glycoconjugates with a carbamate-linked cyclopropene reporter. Bioconjug Chem (2013) 0.86
Direct sensing of 5-methylcytosine by polymerase chain reaction. Angew Chem Int Ed Engl (2014) 0.86
Cytogenetics of extramedullary manifestations in multiple myeloma. Br J Haematol (2013) 0.84
BTB-1: a small molecule inhibitor of the mitotic motor protein Kif18A. Angew Chem Int Ed Engl (2009) 0.84
Specific sequence selection and next generation resequencing of 68 E. coli genes using HybSelect. N Biotechnol (2009) 0.84
Engineered DNA polymerases in biotechnology. Chembiochem (2010) 0.84
Specific incorporation of an artificial nucleotide opposite a mutagenic DNA adduct by a DNA polymerase. J Am Chem Soc (2014) 0.83
Enzymatic synthesis of multiple spin-labeled DNA. Angew Chem Int Ed Engl (2008) 0.83
Anterior, thoracoscopic-assisted reduction and stabilization of a thoracic burst fracture (T8) in a pregnant woman. Eur Spine J (2011) 0.83
Dissecting ubiquitin signaling with linkage-defined and protease resistant ubiquitin chains. Angew Chem Int Ed Engl (2014) 0.83
Structures of KlenTaq DNA polymerase caught while incorporating C5-modified pyrimidine and C7-modified 7-deazapurine nucleoside triphosphates. J Am Chem Soc (2012) 0.83
Lesion bypass activity of DNA polymerase A from the extremely radioresistant organism Deinococcus radiodurans. J Biol Chem (2007) 0.83
Taking fingerprints of DNA polymerases: multiplex enzyme profiling on DNA arrays. Angew Chem Int Ed Engl (2009) 0.83
Similar incidences of TP53 deletions in extramedullary organ infiltrations, soft tissue and osteolyses of patients with multiple myeloma. Anticancer Res (2012) 0.82
Learning from directed evolution: Thermus aquaticus DNA polymerase mutants with translesion synthesis activity. Chembiochem (2011) 0.82
Novel DNA catalysts based on G-quadruplex recognition. Chembiochem (2008) 0.82
Synthesis and stability of phosphate modified ATP analogues. J Org Chem (2012) 0.82
Screening mutant libraries of T7 RNA polymerase for candidates with increased acceptance of 2'-modified nucleotides. Chem Commun (Camb) (2012) 0.82
A class of mild surfactants that keep integral membrane proteins water-soluble for functional studies and crystallization. Mol Membr Biol (2011) 0.82
Red-light-controlled protein-RNA crosslinking with a genetically encoded furan. Angew Chem Int Ed Engl (2013) 0.81
Structures of DNA polymerases caught processing size-augmented nucleotide probes. Angew Chem Int Ed Engl (2010) 0.81
A new photoactive building block for investigation of DNA backbone interactions: photoaffinity labeling of human DNA polymerase beta. Chembiochem (2006) 0.81
PTEN deletion is rare but often homogeneous in gastric cancer. J Clin Pathol (2012) 0.81
Replacing 32 proline residues by a noncanonical amino acid results in a highly active DNA polymerase. J Am Chem Soc (2010) 0.81
Amino acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase. J Biol Chem (2012) 0.80
Small Molecule Inhibitors of Human DNA Polymerase λ. ACS Chem Biol (2011) 0.80
Enzymatic synthesis of perfluoroalkylated DNA. Bioorg Med Chem (2009) 0.80
Directed evolution of DNA polymerases: construction and screening of DNA polymerase mutant libraries. Curr Protoc Chem Biol (2010) 0.80
Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML. Blood (2002) 0.80
Diamondoid-modified DNA. Org Biomol Chem (2011) 0.79
Evolved sequence contexts for highly efficient amber suppression with noncanonical amino acids. ACS Chem Biol (2014) 0.79
Solution structure and conformational dynamics of deoxyxylonucleic acids (dXNA): an orthogonal nucleic acid candidate. Chemistry (2011) 0.79
Depth of submucosal tumor infiltration and its relevance in lymphatic metastasis formation for T1b squamous cell and adenocarcinomas of the esophagus. J Gastrointest Surg (2013) 0.79
Low N-acetyltransferase 2 activity in isoniazid-associated acute hepatitis requiring liver transplantation. Transpl Int (2009) 0.79
Tuning PCR specificity by chemically modified primer probes. Angew Chem Int Ed Engl (2002) 0.79
4'C-ethynyl-thymidine acts as a chain terminator during DNA-synthesis catalyzed by HIV-1 reverse transcriptase. Bioorg Med Chem Lett (2005) 0.79
The use of enzymes for construction of DNA-based objects and assemblies. Chem Soc Rev (2011) 0.79
Thiamine pyrophosphate stimulates acetone activation by Desulfococcus biacutus as monitored by a fluorogenic ATP analogue. ACS Chem Biol (2014) 0.79
Efficient labelling of enzymatically synthesized vinyl-modified DNA by an inverse-electron-demand Diels-Alder reaction. Chem Commun (Camb) (2014) 0.79
Directed DNA polymerase evolution: effects of mutations in motif C on the mismatch-extension selectivity of thermus aquaticus DNA polymerase. Chembiochem (2007) 0.79
New branched DNA constructs. Chemistry (2007) 0.79
Direct measurement of electrical transport through G-quadruplex DNA with mechanically controllable break junction electrodes. Angew Chem Int Ed Engl (2010) 0.78
Structure and function of an RNA-reading thermostable DNA polymerase. Angew Chem Int Ed Engl (2013) 0.78
Differential minor groove interactions between DNA polymerase and sugar backbone of primer and template strands. J Am Chem Soc (2002) 0.78
Determination of the relative configuration of a five-membered lactone from residual dipolar couplings. Angew Chem Int Ed Engl (2006) 0.78
Proline-modified DNA as catalyst of the aldol reaction. Angew Chem Int Ed Engl (2007) 0.78
Formation of ubiquitin dimers via azide-alkyne click reaction. Methods Mol Biol (2012) 0.78
Programmable and highly resolved in vitro detection of 5-methylcytosine by TALEs. Angew Chem Int Ed Engl (2014) 0.78
Concordance of HER2 status in primary tumour and lymph node metastases in patients with esophageal carcinoma. Anticancer Res (2013) 0.78
Structural basis of furan-amino acid recognition by a polyspecific aminoacyl-tRNA-synthetase and its genetic encoding in human cells. Chembiochem (2014) 0.78
Hydrophobic amino acid and single-atom substitutions increase DNA polymerase selectivity. Chem Biol (2007) 0.78
A highly active DNA polymerase with a fluorous core. Angew Chem Int Ed Engl (2010) 0.78
Human DNA polymerase beta mutations allowing efficient abasic site bypass. J Biol Chem (2010) 0.78
MALDI imaging on large-scale tissue microarrays identifies molecular features associated with tumour phenotype in oesophageal cancer. Histopathology (2013) 0.78
Expanding the scope of human DNA polymerase λ and β inhibitors. ACS Chem Biol (2013) 0.78
New strategies for DNA polymerase library screening. Nucleic Acids Symp Ser (Oxf) (2008) 0.78
Synthesis and fluorescence characteristics of ATP-based FRET probes. Org Biomol Chem (2013) 0.78
Synthesis of DNA oligonucleotides containing 5-(mercaptomethyl)-2'-deoxyuridine moieties. Bioorg Med Chem (2006) 0.78
Mutant DNA polymerase for improved detection of single-nucleotide variations in microarrayed primer extension. Chembiochem (2008) 0.78
Patients with multiple myeloma develop SOX2-specific autoantibodies after allogeneic stem cell transplantation. Clin Dev Immunol (2011) 0.78
Increased single-nucleotide discrimination in allele-specific polymerase chain reactions through primer probes bearing nucleobase and 2'-deoxyribose modifications. Chemistry (2007) 0.78
Exploring the effects of active site constraints on HIV-1 reverse transcriptase DNA polymerase fidelity. J Biol Chem (2002) 0.78