Published in Biochim Biophys Acta on November 04, 2002
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci (2010) 5.27
Glutamate receptor dynamics in dendritic microdomains. Neuron (2008) 3.28
Mechanisms of neurodegeneration and regeneration in alcoholism. Alcohol Alcohol (2008) 2.52
Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability. J Neurosci (2006) 1.94
Caldendrin-Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus. PLoS Biol (2008) 1.79
Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB. EMBO J (2004) 1.65
The dichotomy of NMDA receptor signaling. Neuroscientist (2007) 1.61
Extrasynaptic and synaptic NMDA receptors form stable and uniform pools in rat hippocampal slices. J Physiol (2007) 1.56
Coupling of the NMDA receptor to neuroprotective and neurodestructive events. Biochem Soc Trans (2009) 1.50
Mechanisms of specificity in neuronal activity-regulated gene transcription. Prog Neurobiol (2011) 1.49
BDNF-exercise interactions in the recovery of symmetrical stepping after a cervical hemisection in rats. Neuroscience (2008) 1.43
In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death. Neuroscience (2008) 1.36
Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load. J Physiol (2007) 1.27
Ubiquitin proteasome-mediated synaptic reorganization: a novel mechanism underlying rapid ischemic tolerance. J Neurosci (2008) 1.24
Synaptic NMDA receptors mediate hypoxic excitotoxic death. J Neurosci (2012) 1.22
Compartmentalized NMDA receptor signalling to survival and death. J Physiol (2007) 1.21
CREB and NF-kappaB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death. Cell Mol Neurobiol (2006) 1.20
Activity-dependent regulation of surface glucose transporter-3. J Neurosci (2011) 1.15
Calcium signaling in synapse-to-nucleus communication. Cold Spring Harb Perspect Biol (2011) 1.12
Nuclear translocation of jacob in hippocampal neurons after stimuli inducing long-term potentiation but not long-term depression. PLoS One (2011) 1.09
Influence of GluN2 subunit identity on NMDA receptor function. Neuropharmacology (2013) 1.07
Age dependency of inhibition of alpha7 nicotinic receptors and tonically active N-methyl-D-aspartate receptors by endogenously produced kynurenic acid in the brain. J Pharmacol Exp Ther (2011) 1.00
Indistinguishable synaptic pharmacodynamics of the N-methyl-D-aspartate receptor channel blockers memantine and ketamine. Mol Pharmacol (2013) 0.99
Brevetoxin activation of voltage-gated sodium channels regulates Ca dynamics and ERK1/2 phosphorylation in murine neocortical neurons. J Neurochem (2004) 0.99
Nuclear calcium sensors reveal that repetition of trains of synaptic stimuli boosts nuclear calcium signaling in CA1 pyramidal neurons. Biophys J (2010) 0.97
A quantitative method to assess extrasynaptic NMDA receptor function in the protective effect of synaptic activity against neurotoxicity. BMC Neurosci (2008) 0.96
Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors. Neuroscience (2010) 0.95
Tonic NMDA receptor-mediated current in prefrontal cortical pyramidal cells and fast-spiking interneurons. J Neurophysiol (2012) 0.95
Protein kinase CK2 modulates synaptic plasticity by modification of synaptic NMDA receptors in the hippocampus. J Physiol (2008) 0.93
Differential role of N-methyl-D-aspartate receptor subunits 2A and 2B in mediating phencyclidine-induced perinatal neuronal apoptosis and behavioral deficits. Neuroscience (2009) 0.93
Update on the neurobiology of schizophrenia: a role for extracellular microdomains. Minerva Psichiatr (2012) 0.91
Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain. Neurosci Lett (2011) 0.89
Decreased NR1 phosphorylation and decreased NMDAR function in hibernating Arctic ground squirrels. J Neurosci Res (2006) 0.89
Antagonism of purinergic signalling improves recovery from traumatic brain injury. Brain (2013) 0.89
Platelet-derived growth factor selectively inhibits NR2B-containing N-methyl-D-aspartate receptors in CA1 hippocampal neurons. J Biol Chem (2008) 0.88
Switching of N-methyl-D-aspartate (NMDA) receptor-favorite intracellular signal pathways from ERK1/2 protein to p38 mitogen-activated protein kinase leads to developmental changes in NMDA neurotoxicity. J Biol Chem (2011) 0.88
Nuclear calcium signaling regulates nuclear export of a subset of class IIa histone deacetylases following synaptic activity. J Biol Chem (2013) 0.88
Extrasynaptic N-methyl-D-aspartate (NMDA) receptor stimulation induces cytoplasmic translocation of the CDKL5 kinase and its proteasomal degradation. J Biol Chem (2011) 0.87
Motor impairments, striatal degeneration, and altered dopamine-glutamate interplay in mice lacking PSD-95. J Neurogenet (2014) 0.87
Modulation of extrasynaptic NMDA receptors by synaptic and tonic zinc. Proc Natl Acad Sci U S A (2015) 0.86
Extrasynaptic NMDA Receptor in Excitotoxicity: Function Revisited. Neuroscientist (2014) 0.84
The role of excitotoxic programmed necrosis in acute brain injury. Comput Struct Biotechnol J (2015) 0.83
Conantokins inhibit NMDAR-dependent calcium influx in developing rat hippocampal neurons in primary culture with resulting effects on CREB phosphorylation. Mol Cell Neurosci (2010) 0.83
NAAG, NMDA receptor and psychosis. Curr Med Chem (2012) 0.83
A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons. BMC Neurosci (2009) 0.82
Stretch injury selectively enhances extrasynaptic, GluN2B-containing NMDA receptor function in cortical neurons. J Neurophysiol (2013) 0.81
Localization of excitatory amino acid transporters EAAT1 and EAAT2 in human postmortem cortex: a light and electron microscopic study. Neuroscience (2014) 0.81
Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival. BMC Neurosci (2012) 0.81
Inhibition of GluN2A-containing N-methyl-D-aspartate receptors by 2-naphthoic acid. Mol Pharmacol (2013) 0.78
Opposing action of conantokin-G on synaptically and extrasynaptically-activated NMDA receptors. Neuropharmacology (2012) 0.78
Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription. J Neurosci (2009) 0.78
Antagonist properties of Conus parius peptides on N-methyl-D-aspartate receptors and their effects on CREB signaling. PLoS One (2013) 0.77
Alzheimer's disease and metals: a review of the involvement of cellular membrane receptors in metallosignalling. Int J Alzheimers Dis (2011) 0.77
Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors. J Biol Chem (2015) 0.77
Inhibition of acetylcholinesterase modulates NMDA receptor antagonist mediated alterations in the developing brain. Int J Mol Sci (2014) 0.76
Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure. Neuropharmacology (2013) 0.76
Development of NMDAR antagonists with reduced neurotoxic side effects: a study on GK11. PLoS One (2013) 0.76
Dysregulation of Corticostriatal Connectivity in Huntington's Disease: A Role for Dopamine Modulation. J Huntingtons Dis (2016) 0.75
Dissociable effects of NR2A and NR2B NMDA receptor antagonism on cognitive flexibility but not pattern separation. Psychopharmacology (Berl) (2015) 0.75
Pathogenic Roles of Glutamic Acid Decarboxylase 65 Autoantibodies in Cerebellar Ataxias. J Immunol Res (2017) 0.75
Glutamate Neurotransmission in Rodent Models of Traumatic Brain Injury. J Neurotrauma (2016) 0.75
The Involvement of the Decrease of Astrocytic Wnt5a in the Cognitive Decline in Minimal Hepatic Encephalopathy. Mol Neurobiol (2016) 0.75
Hypoxia associated NMDA receptor 2 subunit composition: developmental comparison between the hypoxia-tolerant subterranean mole-rat, Spalax, and the hypoxia-sensitive rat. J Comp Physiol B (2012) 0.75
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci (2010) 5.27
The Yin and Yang of NMDA receptor signalling. Trends Neurosci (2003) 2.83
Neuronal activity-dependent nucleocytoplasmic shuttling of HDAC4 and HDAC5. J Neurochem (2003) 2.20
Nuclear Ca2+ and the cAMP response element-binding protein family mediate a late phase of activity-dependent neuroprotection. J Neurosci (2005) 2.16
Decoding NMDA receptor signaling: identification of genomic programs specifying neuronal survival and death. Neuron (2007) 2.08
Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability. J Neurosci (2006) 1.94
Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity. PLoS Genet (2009) 1.72
Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities. Nat Neurosci (2012) 1.66
Microelectrode array recordings of cultured hippocampal networks reveal a simple model for transcription and protein synthesis-dependent plasticity. J Physiol (2004) 1.41
Synaptic activity induces dramatic changes in the geometry of the cell nucleus: interplay between nuclear structure, histone H3 phosphorylation, and nuclear calcium signaling. J Neurosci (2009) 1.36
Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals. Nat Commun (2013) 1.30
Nuclear Ca2+ and CaM kinase IV specify hormonal- and Notch-responsiveness. J Neurochem (2005) 1.22
Opposing roles of synaptic and extrasynaptic NMDA receptors in neuronal calcium signalling and BDNF gene regulation. Curr Opin Neurobiol (2003) 1.17
Calcium signaling in synapse-to-nucleus communication. Cold Spring Harb Perspect Biol (2011) 1.12
Activity-dependent calcium signaling and ERK-MAP kinases in neurons: a link to structural plasticity of the nucleus and gene transcription regulation. Cell Calcium (2010) 1.10
Synaptic activity and nuclear calcium signaling protect hippocampal neurons from death signal-associated nuclear translocation of FoxO3a induced by extrasynaptic N-methyl-D-aspartate receptors. J Biol Chem (2010) 1.09
Nuclear calcium signaling in spinal neurons drives a genomic program required for persistent inflammatory pain. Neuron (2013) 1.09
Diffusion and not active transport underlies and limits ERK1/2 synapse-to-nucleus signaling in hippocampal neurons. J Biol Chem (2007) 1.07
Synaptic activity-mediated suppression of p53 and induction of nuclear calcium-regulated neuroprotective genes promote survival through inhibition of mitochondrial permeability transition. J Neurosci (2009) 1.06
Nuclear calcium-VEGFD signaling controls maintenance of dendrite arborization necessary for memory formation. Neuron (2011) 1.01
Conjugation of peptides to the passivation shell of gold nanoparticles for targeting of cell-surface receptors. ACS Nano (2010) 0.97
Nuclear calcium sensors reveal that repetition of trains of synaptic stimuli boosts nuclear calcium signaling in CA1 pyramidal neurons. Biophys J (2010) 0.97
A quantitative method to assess extrasynaptic NMDA receptor function in the protective effect of synaptic activity against neurotoxicity. BMC Neurosci (2008) 0.96
Long term recordings with microelectrode arrays: studies of transcription-dependent neuronal plasticity and axonal regeneration. J Physiol Paris (2006) 0.92
Nuclear calcium signaling. Adv Exp Med Biol (2012) 0.90
Calcium signaling in cognition and aging-dependent cognitive decline. Biofactors (2011) 0.90
Calcium signals can freely cross the nuclear envelope in hippocampal neurons: somatic calcium increases generate nuclear calcium transients. BMC Neurosci (2007) 0.88
Nuclear calcium signaling regulates nuclear export of a subset of class IIa histone deacetylases following synaptic activity. J Biol Chem (2013) 0.88
Adeno-associated virus (AAV)-mediated suppression of Ca2+/calmodulin kinase IV activity in the nucleus accumbens modulates emotional behaviour in mice. BMC Neurosci (2007) 0.86
Structural dynamics of the cell nucleus: basis for morphology modulation of nuclear calcium signaling and gene transcription. Nucleus (2011) 0.85
Nuclear calcium signaling controls methyl-CpG-binding protein 2 (MeCP2) phosphorylation on serine 421 following synaptic activity. J Biol Chem (2012) 0.84
Synaptic activity induces signalling to CREB without increasing global levels of cAMP in hippocampal neurons. J Neurochem (2003) 0.83
A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons. BMC Neurosci (2009) 0.82
Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival. BMC Neurosci (2012) 0.81
Filtering, reconstruction, and measurement of the geometry of nuclei from hippocampal neurons based on confocal microscopy data. J Biomed Opt (2008) 0.81
The divergence-convergence model of acquired neuroprotection. Mech Dev (2012) 0.79
Requirement for nuclear calcium signaling in Drosophila long-term memory. Sci Signal (2013) 0.79
Calcium responses to synaptically activated bursts of action potentials and their synapse-independent replay in cultured networks of hippocampal neurons. Biochim Biophys Acta (2013) 0.78
The nuclear calcium signaling target, activating transcription factor 3 (ATF3), protects against dendrotoxicity and facilitates the recovery of synaptic transmission after an excitotoxic insult. J Biol Chem (2014) 0.78
Reliable optical detection of coherent neuronal activity in fast oscillating networks in vitro. Neuroimage (2011) 0.78
Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure. Neuropharmacology (2013) 0.76
Dysfunction of neuronal calcium signaling in aging and disease. Cell Tissue Res (2014) 0.76