Published in J Biol Chem on November 21, 2002
The mammalian ovary from genesis to revelation. Endocr Rev (2009) 2.31
Hypergonadotropic ovarian failure associated with an inherited mutation of human bone morphogenetic protein-15 (BMP15) gene. Am J Hum Genet (2004) 1.72
Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions. Proc Natl Acad Sci U S A (2013) 1.42
Integral role of GDF-9 and BMP-15 in ovarian function. Mol Reprod Dev (2011) 1.26
Posttranslational processing of mouse and human BMP-15: potential implication in the determination of ovulation quota. Proc Natl Acad Sci U S A (2005) 1.14
Compartmentalizing VEGF-induced ERK2/1 signaling in placental artery endothelial cell caveolae: a paradoxical role of caveolin-1 in placental angiogenesis in vitro. Mol Endocrinol (2009) 1.11
A unique preovulatory expression pattern plays a key role in the physiological functions of BMP-15 in the mouse. Proc Natl Acad Sci U S A (2006) 1.07
Regulation of ovulation rate in mammals: contribution of sheep genetic models. Reprod Biol Endocrinol (2006) 1.03
Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15. Mol Hum Reprod (2011) 1.01
Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep. PLoS Genet (2013) 0.96
Designer TGFβ superfamily ligands with diversified functionality. PLoS One (2011) 0.96
Phosphorylation of bone morphogenetic protein-15 and growth and differentiation factor-9 plays a critical role in determining agonistic or antagonistic functions. Endocrinology (2007) 0.89
Variation in bone morphogenetic protein 15 is not associated with spontaneous human dizygotic twinning. Hum Reprod (2008) 0.89
Characterization of the post-translational modification of recombinant human BMP-15 mature protein. Protein Sci (2008) 0.87
Deciphering mechanisms controlling placental artery endothelial cell migration stimulated by vascular endothelial growth factor. Endocrinology (2010) 0.86
Transcriptional regulation of endothelial nitric oxide synthase expression in uterine artery endothelial cells by c-Jun/AP-1. Mol Cell Endocrinol (2007) 0.85
Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality. J Biol Chem (2015) 0.85
Impaired production of BMP-15 and GDF-9 mature proteins derived from proproteins WITH mutations in the proregion. Mol Cell Endocrinol (2010) 0.83
Direct evidence on the contribution of a missense mutation in GDF9 to variation in ovulation rate of Finnsheep. PLoS One (2014) 0.82
BMP-functionalised coatings to promote osteogenesis for orthopaedic implants. Int J Mol Sci (2014) 0.81
Reply to Mottershead et al.: GDF9:BMP15 heterodimers are potent regulators of ovarian functions. Proc Natl Acad Sci U S A (2013) 0.76
Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9:BMP15 heterodimer activities. Biol Reprod (2014) 0.76
Biomaterials with Antibacterial and Osteoinductive Properties to Repair Infected Bone Defects. Int J Mol Sci (2016) 0.76
The TGF-β Family in the Reproductive Tract. Cold Spring Harb Perspect Biol (2017) 0.76
Identification and characterization of canine growth differentiation factor-9 and its splicing variant. Gene (2012) 0.75
Selection of ovine oocytes by brilliant cresyl blue staining. J Biomed Biotechnol (2012) 0.75
Extensive sequence turnover of the signal peptides of members of the GDF/BMP family: exploring their evolutionary landscape. Biol Direct (2009) 0.75
Tribulus terrestris Alters the Expression of Growth Differentiation Factor 9 and Bone Morphogenetic Protein 15 in Rabbit Ovaries of Mothers and F1 Female Offspring. PLoS One (2016) 0.75
REGULATION OF AMH BY OOCYTE SPECIFIC GROWTH FACTORS IN HUMAN PRIMARY CUMULUS CELLS. Reproduction (2017) 0.75
The bone morphogenetic protein system in mammalian reproduction. Endocr Rev (2004) 2.64
Abrupt enlargement of adrenal incidentaloma: a case of isolated adrenal metastasis. Endocr J (2005) 1.51
Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells. Development (2007) 1.50
Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells. J Biol Chem (2002) 1.38
Relationships between Causes of Fever of Unknown Origin and Inflammatory Markers: A Multicenter Collaborative Retrospective Study. Intern Med (2015) 1.38
A negative feedback system between oocyte bone morphogenetic protein 15 and granulosa cell kit ligand: its role in regulating granulosa cell mitosis. Proc Natl Acad Sci U S A (2002) 1.35
Integral role of GDF-9 and BMP-15 in ovarian function. Mol Reprod Dev (2011) 1.26
TNF-alpha inhibits BMP-induced osteoblast differentiation through activating SAPK/JNK signaling. Biochem Biophys Res Commun (2007) 1.23
Aberrant expression of growth differentiation factor-9 in oocytes of women with polycystic ovary syndrome. J Clin Endocrinol Metab (2002) 1.21
The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle. Reprod Biol Endocrinol (2003) 1.18
A novel function of bone morphogenetic protein-15 in the pituitary: selective synthesis and secretion of FSH by gonadotropes. Endocrinology (2002) 1.17
Posttranslational processing of mouse and human BMP-15: potential implication in the determination of ovulation quota. Proc Natl Acad Sci U S A (2005) 1.14
Are BMP-15 and GDF-9 primary determinants of ovulation quota in mammals? Trends Endocrinol Metab (2004) 1.14
A unique preovulatory expression pattern plays a key role in the physiological functions of BMP-15 in the mouse. Proc Natl Acad Sci U S A (2006) 1.07
Increased androgen response to follicle-stimulating hormone administration in women with polycystic ovary syndrome. J Clin Endocrinol Metab (2008) 1.05
Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway. J Endocrinol (2008) 1.05
Functional and molecular characterization of naturally occurring mutations in the oocyte-secreted factors bone morphogenetic protein-15 and growth and differentiation factor-9. J Biol Chem (2004) 1.02
Recent trends of hyperuricemia and obesity in Japanese male adolescents, 1991 through 2002. Metabolism (2004) 0.99
Essential role of the oocyte in estrogen amplification of follicle-stimulating hormone signaling in granulosa cells. Endocrinology (2005) 0.98
Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions. J Biol Chem (2007) 0.97
Bone morphogenetic protein 6 (BMP6) and BMP7 inhibit estrogen-induced proliferation of breast cancer cells by suppressing p38 mitogen-activated protein kinase activation. J Endocrinol (2008) 0.97
Oocyte-specific overexpression of mouse bone morphogenetic protein-15 leads to accelerated folliculogenesis and an early onset of acyclicity in transgenic mice. Endocrinology (2008) 0.95
Effects of bone morphogenetic protein-7 (BMP-7) on primordial follicular growth in the mouse ovary. Mol Reprod Dev (2004) 0.95
Follicle-stimulating hormone regulates oocyte growth by modulation of expression of oocyte and granulosa cell factors. Endocrinology (2004) 0.93
Molecular biology and physiological role of the oocyte factor, BMP-15. Mol Cell Endocrinol (2005) 0.91
Estrogen and glucocorticoid regulate osteoblast differentiation through the interaction of bone morphogenetic protein-2 and tumor necrosis factor-alpha in C2C12 cells. Mol Cell Endocrinol (2010) 0.90
Effects of peroxisome proliferator-activated receptor activation on gonadotropin transcription and cell mitosis induced by bone morphogenetic proteins in mouse gonadotrope LbetaT2 cells. J Endocrinol (2007) 0.90
Involvement of the bone morphogenetic protein system in endothelin- and aldosterone-induced cell proliferation of pulmonary arterial smooth muscle cells isolated from human patients with pulmonary arterial hypertension. Hypertens Res (2010) 0.90
Phosphorylation of bone morphogenetic protein-15 and growth and differentiation factor-9 plays a critical role in determining agonistic or antagonistic functions. Endocrinology (2007) 0.89
Differential regulation of steroidogenesis by bone morphogenetic proteins in granulosa cells: involvement of extracellularly regulated kinase signaling and oocyte actions in follicle-stimulating hormone-induced estrogen production. Endocrinology (2006) 0.89
Peroxisome proliferator-activated receptor activity is involved in the osteoblastic differentiation regulated by bone morphogenetic proteins and tumor necrosis factor-α. Mol Cell Endocrinol (2011) 0.89
Diagnostic workup for fever of unknown origin: a multicenter collaborative retrospective study. BMJ Open (2013) 0.88
Estrogen facilitates osteoblast differentiation by upregulating bone morphogenetic protein-4 signaling. Steroids (2013) 0.88
Golgi apparatus casein kinase phosphorylates bioactive Ser-6 of bone morphogenetic protein 15 and growth and differentiation factor 9. FEBS Lett (2010) 0.88
Antagonistic effects of bone morphogenetic protein-4 and -7 on renal mesangial cell proliferation induced by aldosterone through MAPK activation. Am J Physiol Renal Physiol (2007) 0.87
Characterization of the post-translational modification of recombinant human BMP-15 mature protein. Protein Sci (2008) 0.87
Gastric diverticulum simulating left adrenal incidentaloma in a hypertensive patient. Endocr J (2007) 0.86
Simvastatin inhibits osteoclast differentiation induced by bone morphogenetic protein-2 and RANKL through regulating MAPK, AKT and Src signaling. Regul Pept (2010) 0.85
Mutual regulation of follicle-stimulating hormone signaling and bone morphogenetic protein system in human granulosa cells. Biol Reprod (2006) 0.85
An aberrant ACTH-producing ectopic pituitary adenoma in the sphenoid sinus. Endocr J (2004) 0.85
Effect of etidronate on intraosseous meningioma. Endocr J (2004) 0.85
Effects of growth hormone reduction in a patient with polycystic ovary syndrome complicated with acromegaly. Endocr J (2008) 0.85
Bone morphogenetic protein-15 in the zebrafish ovary: complementary deoxyribonucleic acid cloning, genomic organization, tissue distribution, and role in oocyte maturation. Endocrinology (2005) 0.84
Myopathy and eosinophilic pneumonia coincidentally induced by treatment with daptomycin. Intern Med (2015) 0.84
Pro-apoptotic effects of imatinib on PDGF-stimulated pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. Int J Cardiol (2011) 0.83
p38-Mitogen-activated protein kinase stimulated steroidogenesis in granulosa cell-oocyte cocultures: role of bone morphogenetic proteins 2 and 4. Endocrinology (2008) 0.83
Aldosterone breakthrough caused by chronic blockage of angiotensin II type 1 receptors in human adrenocortical cells: possible involvement of bone morphogenetic protein-6 actions. Endocrinology (2008) 0.83
Impaired production of BMP-15 and GDF-9 mature proteins derived from proproteins WITH mutations in the proregion. Mol Cell Endocrinol (2010) 0.83
Involvement of bone morphogenetic protein-6 in differential regulation of aldosterone production by angiotensin II and potassium in human adrenocortical cells. Endocrinology (2006) 0.82
Rhabdomyosarcoma discovered in the adrenal region of an elderly hypertensive patient. Hypertens Res (2011) 0.82
Inhibitory effects of simvastatin on platelet-derived growth factor signaling in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. J Cardiovasc Pharmacol (2010) 0.81
Manifestation of rheumatoid arthritis after transsphenoidal surgery in a patient with acromegaly. Endocr J (2006) 0.81
Functional roles of the bone morphogenetic protein system in thyrotropin signaling in porcine thyroid cells. Biochem Biophys Res Commun (2005) 0.81
Follistatin gene expression by gonadotropin-releasing hormone: a role for cyclic AMP and mitogen-activated protein kinase signaling pathways in clonal gonadotroph LbetaT2 cells. Mol Cell Endocrinol (2009) 0.81
Systemic varicella-zoster virus infection in two critically ill patients in an intensive care unit. Virol J (2013) 0.81
Regulatory role of kit ligand-c-kit interaction and oocyte factors in steroidogenesis by rat granulosa cells. Mol Cell Endocrinol (2012) 0.81
A Nephrostomy-associated Urinary Tract Infection Caused by Elizabethkingia meningoseptica. Intern Med (2015) 0.81
Pregnancy-associated plasma protein-a production in rat granulosa cells: stimulation by follicle-stimulating hormone and inhibition by the oocyte-derived bone morphogenetic protein-15. Endocrinology (2004) 0.80
An elderly patient with sarcoidosis manifesting panhypopituitarism with central diabetes insipidus. Endocr J (2007) 0.80
Bone morphogenetic protein-3b (BMP-3b) inhibits osteoblast differentiation via Smad2/3 pathway by counteracting Smad1/5/8 signaling. Mol Cell Endocrinol (2011) 0.80
Regulation of GNRH production by estrogen and bone morphogenetic proteins in GT1-7 hypothalamic cells. J Endocrinol (2009) 0.80
A novel antagonistic effect of the bone morphogenetic protein system on prolactin actions in regulating steroidogenesis by granulosa cells. Endocrinology (2010) 0.80
Involvement of activin/BMP system in development of human pituitary gonadotropinomas and nonfunctioning adenomas. Biochem Biophys Res Commun (2003) 0.79
Functional relationship between fibroblast growth factor-8 and bone morphogenetic proteins in regulating steroidogenesis by rat granulosa cells. Mol Cell Endocrinol (2010) 0.79
Essential but differential role of FOXL2wt and FOXL2C134W in GDF-9 stimulation of follistatin transcription in co-operation with Smad3 in the human granulosa cell line COV434. Mol Cell Endocrinol (2013) 0.79
Induction of tumour necrosis factor receptor-expressing macrophages by interleukin-10 and macrophage colony-stimulating factor in rheumatoid arthritis. Arthritis Res Ther (2006) 0.79
Complication of chronic eosinophilic pneumonia in an elderly patient with Sjögren syndrome. Acta Med Okayama (2015) 0.79
Comprehensive analysis of systemically disseminated ST8/non-USA300 type community-acquired methicillin-resistant Staphylococcus aureus infection. Intern Med (2014) 0.79
Involvement of bone morphogenetic protein-4 in GH regulation by octreotide and bromocriptine in rat pituitary GH3 cells. J Endocrinol (2008) 0.78
Group A streptococcal meningitis in a patient with palmoplantar pustulosis. Intern Med (2013) 0.78
Melatonin receptor activation suppresses adrenocorticotropin production via BMP-4 action by pituitary AtT20 cells. Mol Cell Endocrinol (2013) 0.78
A lethal complication, acute necrotizing pancreatitis, of Turner's Syndrome with primary hyperparathyroidism. Endocr J (2003) 0.78
Acute generalized exanthematous pustulosis caused by daptomycin in a critically ill burn victim. Intern Med (2014) 0.78
A rare tumor in the adrenal region: neuron-specific enolase (NSE)-producing leiomyosarcoma in an elderly hypertensive patient. Endocr J (2008) 0.78
Enhancement of aldosterone-induced catecholamine production by bone morphogenetic protein-4 through activating Rho and SAPK/JNK pathway in adrenomedullar cells. Am J Physiol Endocrinol Metab (2009) 0.78
Effects of bone morphogenetic protein (BMP) on adrenocorticotropin production by pituitary corticotrope cells: involvement of up-regulation of BMP receptor signaling by somatostatin analogs. Endocrinology (2010) 0.78
GRK-6 mediates FSH action synergistically enhanced by estrogen and the oocyte in rat granulosa cells. Biochem Biophys Res Commun (2013) 0.78
Apparent mineralocorticoid excess manifested in an elderly patient with hypothyroidism. Am J Hypertens (2007) 0.78
Novel action of activin and bone morphogenetic protein in regulating aldosterone production by human adrenocortical cells. Endocrinology (2003) 0.78
Granulosa cell tumor mutant FOXL2C134W suppresses GDF-9 and activin A-induced follistatin transcription in primary granulosa cells. Mol Cell Endocrinol (2013) 0.78
Paracrine regulation of theca androgen production by granulosa cells in the ovary. Fertil Steril (2013) 0.78
Role of bradykinin in renoprotective effects by angiotensin II type 1 receptor antagonist in salt-sensitive hypertension. Hypertens Res (2003) 0.77
Mutual interaction of kisspeptin, estrogen and bone morphogenetic protein-4 activity in GnRH regulation by GT1-7 cells. Mol Cell Endocrinol (2013) 0.77
Functional interaction of fibroblast growth factor-8, bone morphogenetic protein and estrogen receptor in breast cancer cell proliferation. Mol Cell Endocrinol (2011) 0.77
Mutual regulation of growth hormone and bone morphogenetic protein system in steroidogenesis by rat granulosa cells. Endocrinology (2011) 0.77
Interaction between gonadotropin-releasing hormone and bone morphogenetic protein-6 and -7 signaling in LβT2 gonadotrope cells. Mol Cell Endocrinol (2011) 0.77
Relapsing Polychondritis Followed Up with FDG-PET. Intern Med (2015) 0.77
Actinomyces meyeri meningitis: the need for anaerobic cerebrospinal fluid cultures. Intern Med (2014) 0.77
Activities of bone morphogenetic proteins in prolactin regulation by somatostatin analogs in rat pituitary GH3 cells. Mol Cell Endocrinol (2010) 0.76
Roles of bone morphogenetic protein-6 in aldosterone regulation by adrenocortical cells. Acta Med Okayama (2010) 0.76
Long-term observation of osteomalacia caused by adefovir-induced Fanconi's syndrome. Acta Med Okayama (2014) 0.76
A Rare Case of Diffuse Large B-cell Lymphoma in a Patient with IgG4-Related Autoimmune Pancreatitis. Acta Med Okayama (2016) 0.76
Primary aldosteronism caused by a unilateral adrenal adenoma accompanied by autonomous cortisol secretion. Hypertens Res (2007) 0.76