Published in J Neurosci on December 01, 2002
WNK kinases regulate thiazide-sensitive Na-Cl cotransport. J Clin Invest (2003) 3.67
In vivo mammalian brain imaging using one- and two-photon fluorescence microendoscopy. J Neurophysiol (2004) 3.28
Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6. Pflugers Arch (2003) 2.45
GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex. Neuron (2007) 2.23
How to build a central synapse: clues from cell culture. Trends Neurosci (2005) 1.94
Recombinant probes for visualizing endogenous synaptic proteins in living neurons. Neuron (2013) 1.80
TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nat Neurosci (2011) 1.67
A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response. J Neurosci (2009) 1.62
Quantitative fluorescence microscopy using supported lipid bilayer standards. Biophys J (2008) 1.55
Deconvolving single-molecule intensity distributions for quantitative microscopy measurements. Biophys J (2007) 1.32
Raphe serotonin neurons are not homogenous: electrophysiological, morphological and neurochemical evidence. Neuropharmacology (2011) 1.30
Quantification and cell-to-cell variation of vascular endothelial growth factor receptors. Exp Cell Res (2010) 1.14
Sec24- and ARFGAP1-dependent trafficking of GABA transporter-1 is a prerequisite for correct axonal targeting. J Neurosci (2008) 1.12
GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET. J Gen Physiol (2009) 1.10
Mutations in the GABA Transporter SLC6A1 Cause Epilepsy with Myoclonic-Atonic Seizures. Am J Hum Genet (2015) 1.09
GABA and Glutamate Transporters in Brain. Front Endocrinol (Lausanne) (2013) 1.06
Fast homeostatic plasticity of inhibition via activity-dependent vesicular filling. PLoS One (2008) 1.05
The Caenorhabditis elegans snf-11 gene encodes a sodium-dependent GABA transporter required for clearance of synaptic GABA. Mol Biol Cell (2006) 1.02
Besides Purkinje cells and granule neurons: an appraisal of the cell biology of the interneurons of the cerebellar cortex. Histochem Cell Biol (2008) 0.98
Astrocytes as gatekeepers of GABAB receptor function. J Neurosci (2010) 0.97
Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice. Epilepsy Res (2011) 0.92
Localization and function of GABA transporters in the globus pallidus of parkinsonian monkeys. Exp Neurol (2010) 0.89
Cell autonomy, receptor autonomy, and thermodynamics in nicotine receptor up-regulation. Biochem Pharmacol (2007) 0.89
Substrate-mediated regulation of gamma-aminobutyric acid transporter 1 in rat brain. Neuropharmacology (2007) 0.89
Novel properties of a mouse gamma-aminobutyric acid transporter (GAT4). J Membr Biol (2005) 0.88
Förster resonance energy transfer (FRET) correlates of altered subunit stoichiometry in cys-loop receptors, exemplified by nicotinic α4β2. Int J Mol Sci (2012) 0.88
Structure, function, and plasticity of GABA transporters. Front Cell Neurosci (2014) 0.86
Ezrin mediates tethering of the gamma-aminobutyric acid transporter GAT1 to actin filaments via a C-terminal PDZ-interacting domain. Biophys J (2009) 0.86
Turnover rate of the gamma-aminobutyric acid transporter GAT1. J Membr Biol (2007) 0.86
Rapid regulation of tonic GABA currents in cultured rat hippocampal neurons. J Neurophysiol (2012) 0.86
Relations between substrate affinities and charge equilibration rates in the rat GABA cotransporter GAT1. J Physiol (2004) 0.83
Dynamics of forward and reverse transport by the glial glycine transporter, glyt1b. Biophys J (2005) 0.82
Deletion of the γ-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents. J Biol Chem (2012) 0.81
Cl⁻ homeodynamics in gap junction-coupled astrocytic networks on activation of GABAergic synapses. J Physiol (2013) 0.81
Quantitative characterization of cellular membrane-receptor heterogeneity through statistical and computational modeling. PLoS One (2014) 0.80
Differential modulation of N-type calcium channels by micro-opioid receptors in oxytocinergic versus vasopressinergic neurohypophysial terminals. J Cell Physiol (2010) 0.80
Plasticity of GABA transporters: an unconventional route to shape inhibitory synaptic transmission. Front Cell Neurosci (2014) 0.79
Synaptic GABA release prevents GABA transporter type-1 reversal during excessive network activity. Nat Commun (2015) 0.76
Localization and expression of GABA transporters in the suprachiasmatic nucleus. Eur J Neurosci (2015) 0.76
Essential roles of GABA transporter-1 in controlling rapid eye movement sleep and in increased slow wave activity after sleep deprivation. PLoS One (2013) 0.75
Counting numbers of synaptic proteins: absolute quantification and single molecule imaging techniques. Neurophotonics (2016) 0.75
γ-aminobutyric acid transporter-1 is involved in anxiety-like behaviors and cognitive function in knockout mice. Exp Ther Med (2015) 0.75
Impairment of GABA transporter GAT-1 terminates cortical recurrent network activity via enhanced phasic inhibition. Front Neural Circuits (2013) 0.75
Robust Asymmetric Localization of Planar Polarity Proteins Is Associated with Organization into Signalosome-like Domains of Variable Stoichiometry. Cell Rep (2016) 0.75
Modeling Suggests TRPC3 Hydrogen Bonding and Not Phosphorylation Contributes to the Ataxia Phenotype of the Moonwalker Mouse. Biochemistry (2015) 0.75
A Role for Diminished GABA Transporter Activity in the Cortical Discharge Phenotype of MeCP2-Deficient Mice. Neuropsychopharmacology (2015) 0.75
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
PatternHunter: faster and more sensitive homology search. Bioinformatics (2002) 35.65
ZOOM! Zillions of oligos mapped. Bioinformatics (2008) 29.78
Single-molecule DNA sequencing of a viral genome. Science (2008) 11.66
Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature (2009) 10.31
Clinical assessment incorporating a personal genome. Lancet (2010) 10.18
Epidermal electronics. Science (2011) 8.65
Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood. Proc Natl Acad Sci U S A (2008) 8.38
Single-molecule sequencing of an individual human genome. Nat Biotechnol (2009) 8.35
Single-cell dissection of transcriptional heterogeneity in human colon tumors. Nat Biotechnol (2011) 7.84
Dissecting biological "dark matter" with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth. Proc Natl Acad Sci U S A (2007) 7.82
Microfluidic large-scale integration. Science (2002) 7.64
The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev Cell (2003) 6.86
Whole-genome molecular haplotyping of single cells. Nat Biotechnol (2010) 6.77
Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization. Science (2004) 5.94
Developing optofluidic technology through the fusion of microfluidics and optics. Nature (2006) 5.82
Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing. Nature (2010) 5.27
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol (2009) 5.27
Sequence information can be obtained from single DNA molecules. Proc Natl Acad Sci U S A (2003) 5.24
Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke. Nature (2010) 5.24
Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR. Proc Natl Acad Sci U S A (2006) 5.21
A systems approach to measuring the binding energy landscapes of transcription factors. Science (2007) 5.06
PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. J Exp Med (2010) 4.74
PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometry. Rapid Commun Mass Spectrom (2003) 4.56
High-throughput sequencing of the zebrafish antibody repertoire. Science (2009) 4.46
An immunosurveillance mechanism controls cancer cell ploidy. Science (2012) 4.35
Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors. Proc Natl Acad Sci U S A (2003) 4.33
Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety. Nat Neurosci (2005) 4.17
A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion. Proc Natl Acad Sci U S A (2002) 4.16
Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Sci Transl Med (2012) 4.05
Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells. Nat Struct Mol Biol (2013) 4.04
Genome of a low-salinity ammonia-oxidizing archaeon determined by single-cell and metagenomic analysis. PLoS One (2011) 4.04
Human infection with avian influenza A H7N9 virus: an assessment of clinical severity. Lancet (2013) 3.90
Microfluidic digital PCR enables multigene analysis of individual environmental bacteria. Science (2006) 3.84
Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol (2011) 3.81
Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines. PLoS One (2012) 3.74
APOBEC3 proteins mediate the clearance of foreign DNA from human cells. Nat Struct Mol Biol (2010) 3.61
Long-term monitoring of bacteria undergoing programmed population control in a microchemostat. Science (2005) 3.54
Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm. Cell (2012) 3.52
An integrated microfabricated cell sorter. Anal Chem (2002) 3.43
Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells. J Neurophysiol (2002) 3.43
Microfluidic large-scale integration: the evolution of design rules for biological automation. Annu Rev Biophys Biomol Struct (2007) 3.32
Paternally inherited inactivating mutations of the GNAS1 gene in progressive osseous heteroplasia. N Engl J Med (2002) 3.31
High-frequency oscillations: what is normal and what is not? Epilepsia (2008) 3.26
Mental health system in China: history, recent service reform and future challenges. World Psychiatry (2011) 3.23
Versatile, fully automated, microfluidic cell culture system. Anal Chem (2007) 3.19
The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture. Proc Natl Acad Sci U S A (2006) 3.19
Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel. Nature (2005) 3.18
Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell (2012) 3.16
Local generation of fast ripples in epileptic brain. J Neurosci (2002) 3.13
Non-invasive prenatal measurement of the fetal genome. Nature (2012) 3.11
A synthetic Escherichia coli predator-prey ecosystem. Mol Syst Biol (2008) 2.92
A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale. PLoS Comput Biol (2009) 2.88
The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line. Nat Biotechnol (2011) 2.87
Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics. Science (2005) 2.83
DNACompress: fast and effective DNA sequence compression. Bioinformatics (2002) 2.82
Nanoliter reactors improve multiple displacement amplification of genomes from single cells. PLoS Genet (2007) 2.79
Activation of GABAA receptors: views from outside the synaptic cleft. Neuron (2007) 2.76
Temporal response of the human virome to immunosuppression and antiviral therapy. Cell (2013) 2.72
Lineage structure of the human antibody repertoire in response to influenza vaccination. Sci Transl Med (2013) 2.71
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection. Nature (2011) 2.71
In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron (2008) 2.69
Integrated nanoliter systems. Nat Biotechnol (2003) 2.68
Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell (2008) 2.65
A pilot study of circulating miRNAs as potential biomarkers of early stage breast cancer. PLoS One (2010) 2.64
RGS9 modulates dopamine signaling in the basal ganglia. Neuron (2003) 2.61
Partial genome assembly for a candidate division OP11 single cell from an anoxic spring (Zodletone Spring, Oklahoma). Appl Environ Microbiol (2011) 2.61
Digital PCR provides sensitive and absolute calibration for high throughput sequencing. BMC Genomics (2009) 2.60
Perisynaptic localization of delta subunit-containing GABA(A) receptors and their activation by GABA spillover in the mouse dentate gyrus. J Neurosci (2003) 2.58
High-frequency oscillations after status epilepticus: epileptogenesis and seizure genesis. Epilepsia (2004) 2.58
GABA(A)R plasticity during pregnancy: relevance to postpartum depression. Neuron (2008) 2.55
Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis. Nat Biotechnol (2008) 2.52
Microfluidic single-cell mRNA isolation and analysis. Anal Chem (2006) 2.47
A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates. PLoS One (2007) 2.47
The structural basis of function in Cys-loop receptors. Q Rev Biophys (2010) 2.45
Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6. Pflugers Arch (2003) 2.45
Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease. PLoS Med (2005) 2.43
Th17 and natural Treg cell population dynamics in systemic lupus erythematosus. Arthritis Rheum (2009) 2.43
Discovering patterns to extract protein-protein interactions from full texts. Bioinformatics (2004) 2.42
Retinal ganglion cells do not extend axons by default: promotion by neurotrophic signaling and electrical activity. Neuron (2002) 2.41
A semisynthetic epitope for kinase substrates. Nat Methods (2007) 2.40
Extrasynaptic GABA(A) receptors: their function in the CNS and implications for disease. Neuron (2012) 2.40
Molecular censusing doubles giant panda population estimate in a key nature reserve. Curr Biol (2006) 2.39
Receptors with different affinities mediate phasic and tonic GABA(A) conductances in hippocampal neurons. J Neurosci (2002) 2.39
Analysis of the size distributions of fetal and maternal cell-free DNA by paired-end sequencing. Clin Chem (2010) 2.38
Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. J Neurosci (2007) 2.37
NONCODEv4: exploring the world of long non-coding RNA genes. Nucleic Acids Res (2013) 2.37
Which GABA(A) receptor subunits are necessary for tonic inhibition in the hippocampus? J Neurosci (2008) 2.37
The graft-versus-leukemia effect using matched unrelated donors is not superior to HLA-identical siblings for hematopoietic stem cell transplantation. Blood (2008) 2.35
Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nat Genet (2011) 2.32
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. J Clin Invest (2013) 2.30
RAPTOR: optimal protein threading by linear programming. J Bioinform Comput Biol (2003) 2.27
Regulation of p53 target gene expression by peptidylarginine deiminase 4. Mol Cell Biol (2008) 2.27
Altered expression of the delta subunit of the GABAA receptor in a mouse model of temporal lobe epilepsy. J Neurosci (2004) 2.25
Genetic measurement of memory B-cell recall using antibody repertoire sequencing. Proc Natl Acad Sci U S A (2013) 2.25
Single-cell genomics. Nat Methods (2011) 2.24
Low ethanol concentrations selectively augment the tonic inhibition mediated by delta subunit-containing GABAA receptors in hippocampal neurons. J Neurosci (2004) 2.24