PubRank

Hitoshi Kikutani

Author PubWeight™ 72.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 FARP2 triggers signals for Sema3A-mediated axonal repulsion. Nat Neurosci 2005 2.87
2 Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis. Nat Cell Biol 2006 2.57
3 Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling. Nat Cell Biol 2004 2.39
4 Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. Genes Dev 2004 2.22
5 Semaphorins and their receptors in immune cell interactions. Nat Immunol 2007 2.07
6 Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2. Nature 2002 2.04
7 The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function. Immunity 2012 1.98
8 Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. Nature 2007 1.87
9 Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury. Proc Natl Acad Sci U S A 2007 1.83
10 Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. J Clin Invest 2003 1.80
11 Short-circuiting long-lived humoral immunity by the heightened engagement of CD40. J Clin Invest 2002 1.67
12 Accelerated tumor growth in mice deficient in DNAM-1 receptor. J Exp Med 2008 1.63
13 Cutting Edge: Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease. J Immunol 2002 1.55
14 Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages. J Exp Med 2008 1.53
15 The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion. J Neurosci 2003 1.46
16 Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice. Immunity 2005 1.39
17 Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells. Dev Biol 2008 1.36
18 Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol 2010 1.33
19 Requirement for the lymphocyte semaphorin, CD100, in the induction of antigen-specific T cells and the maturation of dendritic cells. J Immunol 2002 1.33
20 Immune semaphorins: a new area of semaphorin research. J Cell Sci 2003 1.25
21 Bimodal regulation of T cell-mediated immune responses by TIM-4. Int Immunol 2008 1.23
22 Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses. Int Immunol 2003 1.07
23 Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones. Int Immunol 2002 1.06
24 Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice. Proc Natl Acad Sci U S A 2009 1.05
25 Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D. Blood 2010 1.05
26 Immune semaphorins: novel features of neural guidance molecules. J Clin Immunol 2008 1.04
27 Roles of Sema4D-plexin-B1 interactions in the central nervous system for pathogenesis of experimental autoimmune encephalomyelitis. J Immunol 2009 1.02
28 Plexin-A4 negatively regulates T lymphocyte responses. Int Immunol 2008 1.01
29 Control of bone resorption by semaphorin 4D is dependent on ovarian function. PLoS One 2011 1.01
30 Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor. J Exp Med 2012 1.00
31 Immunological functions of the neuropilins and plexins as receptors for semaphorins. Nat Rev Immunol 2013 1.00
32 Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis. Arterioscler Thromb Vasc Biol 2009 0.98
33 Critical role of IkappaB Kinase alpha in TLR7/9-induced type I IFN production by conventional dendritic cells. J Immunol 2010 0.97
34 Semaphorins: a new class of immunoregulatory molecules. Philos Trans R Soc Lond B Biol Sci 2005 0.96
35 CD100 enhances dendritic cell and CD4+ cell activation leading to pathogenetic humoral responses and immune complex glomerulonephritis. J Immunol 2006 0.93
36 Deleterious effects of lymphocytes at the early stage of neurodegeneration in an animal model of amyotrophic lateral sclerosis. J Neuroinflammation 2011 0.92
37 Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals. Int Immunol 2002 0.91
38 Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development. Mol Cell Neurosci 2010 0.91
39 Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements. FASEB J 2010 0.90
40 Roles of the semaphorin family in immune regulation. Adv Immunol 2003 0.90
41 Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment. Int Immunol 2005 0.89
42 Neuropilin-1: the glue between regulatory T cells and dendritic cells? Immunity 2008 0.89
43 The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses. J Exp Med 2011 0.88
44 An inhibitory role for Sema4A in antigen-specific allergic asthma. J Clin Immunol 2012 0.88
45 Deletion of Sema4D gene reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Int J Mol Med 2010 0.88
46 Sema4A induces cell morphological changes through B-type plexin-mediated signaling. Int J Mol Med 2010 0.87
47 Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis. Immunology 2009 0.86
48 Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation. Proc Natl Acad Sci U S A 2012 0.85
49 Semaphorin signaling during cardiac development. Adv Exp Med Biol 2007 0.84
50 Semaphorins and their receptors: novel features of neural guidance molecules. Proc Jpn Acad Ser B Phys Biol Sci 2010 0.84
51 BAFF controls neural cell survival through BAFF receptor. PLoS One 2013 0.83
52 Sema4D/CD100 deficiency leads to superior performance in mouse motor behavior. Can J Neurol Sci 2009 0.82
53 Tim2 is expressed in mouse fetal hepatocytes and regulates their differentiation. Hepatology 2007 0.82
54 Induction of cyclooxygenase-2 in reactive glial cells by the CD40 pathway: relevance to amyotrophic lateral sclerosis. J Neurochem 2004 0.82
55 Peptide analysis, stability studies, and structural modeling explain contradictory peptide motifs and unique properties of the NOD mouse MHC class II molecule H2-A(g7). Eur J Immunol 2002 0.82
56 Significance of glycosylphosphatidylinositol-anchored protein enrichment in lipid rafts for the control of autoimmunity. J Biol Chem 2013 0.82
57 CD100/Sema4D, a lymphocyte semaphorin involved in the regulation of humoral and cellular immune responses. Cytokine Growth Factor Rev 2003 0.82
58 Involvement of Sema4A in the progression of experimental autoimmune myocarditis. FEBS Lett 2008 0.81
59 Semaphorin 4A induces growth cone collapse of hippocampal neurons in a Rho/Rho-kinase-dependent manner. Int J Mol Med 2005 0.81
60 Loss of dopaminergic neurons by the induction of inducible nitric oxide synthase and cyclooxygenase-2 via CD 40: relevance to Parkinson's disease. J Neurosci Res 2005 0.80
61 Partial suppression of M1 microglia by Janus kinase 2 inhibitor does not protect against neurodegeneration in animal models of amyotrophic lateral sclerosis. J Neuroinflammation 2014 0.77