Published in J Neuroimmunol on October 01, 2002
Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. Proc Natl Acad Sci U S A (2005) 1.92
Microglial dysfunction in brain aging and Alzheimer's disease. Biochem Pharmacol (2014) 1.52
Complement in the brain. Mol Immunol (2011) 1.41
Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD). Prog Retin Eye Res (2010) 1.39
Microglia, Alzheimer's disease, and complement. Int J Alzheimers Dis (2012) 1.21
Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease. J Neurol (2008) 1.11
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia. Glia (2012) 1.07
Microglia receptors and their implications in the response to amyloid β for Alzheimer's disease pathogenesis. J Neuroinflammation (2014) 1.03
Peptides and proteins in plasma and cerebrospinal fluid as biomarkers for the prediction, diagnosis, and monitoring of therapeutic efficacy of Alzheimer's disease. Biochim Biophys Acta (2008) 1.01
Factor h: a complement regulator in health and disease, and a mediator of cellular interactions. Biomolecules (2012) 0.99
Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity. J Neuroinflammation (2011) 0.94
CSF Biomarkers for Alzheimer's Disease Diagnosis. Int J Alzheimers Dis (2010) 0.94
Immune aging, dysmetabolism, and inflammation in neurological diseases. Front Neurosci (2015) 0.92
Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration. J Immunol (2014) 0.91
Innate immunity and neuroinflammation. Mediators Inflamm (2013) 0.90
Zinc binding to the Tyr402 and His402 allotypes of complement factor H: possible implications for age-related macular degeneration. J Mol Biol (2011) 0.86
Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment. Alzheimers Res Ther (2014) 0.85
Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation. Front Immunol (2015) 0.84
Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration. J Clin Med (2015) 0.83
CCAAT-enhancer binding protein-β expression and elevation in Alzheimer's disease and microglial cell cultures. PLoS One (2014) 0.80
c-Jun and c-Fos regulate the complement factor H promoter in murine astrocytes. Mol Immunol (2011) 0.79
Using animal models to determine the significance of complement activation in Alzheimer's disease. J Neuroinflammation (2004) 0.79
CFH Variants Affect Structural and Functional Brain Changes and Genetic Risk of Alzheimer's Disease. Neuropsychopharmacology (2015) 0.79
Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH. Neurosci Lett (2012) 0.78
Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis. Cancer Biol Ther (2010) 0.78
Amyloid-β sequester proteins as blood-based biomarkers of cognitive decline. Alzheimers Dement (Amst) (2015) 0.78
CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease. Acta Neuropathol Commun (2016) 0.78
Neuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies? Curr Alzheimer Res (2016) 0.75
Redox Imbalance and Viral Infections in Neurodegenerative Diseases. Oxid Med Cell Longev (2016) 0.75
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J Clin Psychiatry (2007) 7.23
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron (2007) 6.88
The Sun Health Research Institute Brain Donation Program: description and experience, 1987-2007. Cell Tissue Bank (2008) 4.13
Epigenetic mechanisms in Alzheimer's disease. Neurobiol Aging (2011) 3.83
Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease. Neurobiol Aging (2003) 2.96
The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: executive summary. J Heart Lung Transplant (2013) 2.71
Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons. Proc Natl Acad Sci U S A (2008) 2.59
The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Heart Lung Transplant (2010) 2.59
Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature. Cold Spring Harb Perspect Med (2012) 2.36
Gene expression changes in the course of normal brain aging are sexually dimorphic. Proc Natl Acad Sci U S A (2008) 2.29
Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set. Physiol Genomics (2008) 2.11
Long-term destination therapy with the HeartMate XVE left ventricular assist device: improved outcomes since the REMATCH study. Congest Heart Fail (2005) 1.99
Characterization and prognostic value of persistent hyponatremia in patients with severe heart failure in the ESCAPE Trial. Arch Intern Med (2007) 1.98
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics (2006) 1.88
Dispatcher-assisted cardiopulmonary resuscitation: risks for patients not in cardiac arrest. Circulation (2009) 1.71
Epigenetic changes in Alzheimer's disease: decrements in DNA methylation. Neurobiol Aging (2008) 1.60
Inflammation, anti-inflammatory agents and Alzheimer disease: the last 12 years. J Alzheimers Dis (2006) 1.58
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study. J Neuroinflammation (2012) 1.57
Acquired von Willebrand syndrome in continuous-flow ventricular assist device recipients. Ann Thorac Surg (2010) 1.57
Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease. PLoS One (2009) 1.49
Prevalence and clinical characteristics of mental stress-induced myocardial ischemia in patients with coronary heart disease. J Am Coll Cardiol (2013) 1.34
Biomechanical properties of native basement membranes. FEBS J (2007) 1.31
Sorl1 as an Alzheimer's disease predisposition gene? Neurodegener Dis (2007) 1.31
Algorithm for the diagnosis and management of suspected pump thrombus. J Heart Lung Transplant (2013) 1.27
Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease. Neuron (2013) 1.26
Depressive symptoms and mental stress-induced myocardial ischemia in patients with coronary heart disease. Psychosom Med (2013) 1.24
Gene expression correlates of neurofibrillary tangles in Alzheimer's disease. Neurobiol Aging (2005) 1.24
Evidence for an association between KIBRA and late-onset Alzheimer's disease. Neurobiol Aging (2008) 1.24
Assembly of lamina-specific neuronal connections by slit bound to type IV collagen. Cell (2011) 1.22
CCAAT/enhancer binding protein delta (C/EBPdelta) expression and elevation in Alzheimer's disease. Neurobiol Aging (2004) 1.19
Low-dose dobutamine tissue-tagged magnetic resonance imaging with 3-dimensional strain analysis allows assessment of myocardial viability in patients with ischemic cardiomyopathy. Circulation (2006) 1.18
Principal strain orientation in the normal human left ventricle. Ann Thorac Surg (2005) 1.14
Post-cardiac transplant survival after support with a continuous-flow left ventricular assist device: impact of duration of left ventricular assist device support and other variables. J Thorac Cardiovasc Surg (2010) 1.11
Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease. Neurobiol Aging (2012) 1.10
Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish. Mech Dev (2007) 1.06
Effects of estrogen treatment on glutamate uptake in cultured human astrocytes derived from cortex of Alzheimer's disease patients. J Neurochem (2002) 1.02
The heparan sulfate proteoglycan agrin modulates neurite outgrowth mediated by FGF-2. J Neurobiol (2003) 1.02
Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology. Neurobiol Aging (2008) 1.00
Cost of ventricular assist devices: can we afford the progress? Circulation (2013) 0.99
Magnetic resonance imaging-based multiparametric systolic strain analysis and regional contractile heterogeneity in patients with dilated cardiomyopathy. J Heart Lung Transplant (2009) 0.99
Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters. J Biol Chem (2003) 0.99
Age-dependent changes in the structure, composition and biophysical properties of a human basement membrane. Matrix Biol (2010) 0.96
High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation. BMC Genomics (2010) 0.95
Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease. J Comp Neurol (2009) 0.94
Agrin function associated with ocular development is a target of ethanol exposure in embryonic zebrafish. Birth Defects Res A Clin Mol Teratol (2011) 0.93
Quantification of cytokines involved in wound healing using surface plasmon resonance. Anal Chem (2005) 0.93
Embryonic synthesis of the inner limiting membrane and vitreous body. Invest Ophthalmol Vis Sci (2005) 0.93
Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. Birth Defects Res A Clin Mol Teratol (2012) 0.92
Agrin is required for posterior development and motor axon outgrowth and branching in embryonic zebrafish. Glycobiology (2006) 0.90
Molecular and cellular mediators of Alzheimer's disease inflammation. J Alzheimers Dis (2001) 0.88
Amiodarone and bepridil inhibit anthrax toxin entry into host cells. Antimicrob Agents Chemother (2007) 0.88
Generation of transgenic zebrafish expressing green fluorescent protein under control of zebrafish amyloid precursor protein gene regulatory elements. Zebrafish (2007) 0.87
Transitin, a nestin-like intermediate filament protein, mediates cortical localization and the lateral transport of Numb in mitotic avian neuroepithelial cells. Development (2007) 0.87
Reduced RAN expression and disrupted transport between cytoplasm and nucleus; a key event in Alzheimer's disease pathophysiology. PLoS One (2013) 0.87
Positron emission tomography and neuropathologic estimates of fibrillar amyloid-β in a patient with Down syndrome and Alzheimer disease. Arch Neurol (2011) 0.86
Retina development in zebrafish requires the heparan sulfate proteoglycan agrin. Dev Neurobiol (2008) 0.85
Microglial responses to dopamine in a cell culture model of Parkinson's disease. Neurobiol Aging (2008) 0.85
Microglial responses to amyloid beta peptide opsonization and indomethacin treatment. J Neuroinflammation (2005) 0.85
Zebrafish K5 promoter driven GFP expression as a transgenic system for oral research. Oral Oncol (2009) 0.83
Agrin binds alpha-synuclein and modulates alpha-synuclein fibrillation. Glycobiology (2005) 0.83
Expression of collagen XVIII and localization of its glycosaminoglycan attachment sites. J Biol Chem (2002) 0.82
Revascularization for heart failure. Am Heart J (2007) 0.81
Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis. Int J Mol Epidemiol Genet (2009) 0.81
Expression and localization of lactotransferrin messenger RNA in the cortex of Alzheimer's disease. Neurosci Lett (2009) 0.80
Effectiveness of percutaneous coronary intervention in cardiac allograft vasculopathy. Am J Cardiol (2004) 0.78
Combined X-ray diffraction and kinetic depth effect imaging. Opt Express (2011) 0.77
Blood transfusions decrease the incidence of acute rejection in cardiac allograft recipients. J Heart Lung Transplant (2005) 0.77
Organ cross talk in the critically ill: the heart and kidney. Blood Purif (2009) 0.77
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. Circ Heart Fail (2012) 0.76
Pilot investigation of a novel testing strategy for bleeding in ventricular assist device recipients. J Heart Lung Transplant (2012) 0.76
Transgenic overexpression of cdx1b induces metaplastic changes of gene expression in zebrafish esophageal squamous epithelium. Zebrafish (2013) 0.75
Interactions of stroke, nonsteroidal anti-inflammatory drugs, and APOE status in dementia risk. Neurology (2008) 0.75
Transitin is required for the differentiation of avian QM7 myoblasts into myotubes. Dev Dyn (2010) 0.75
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. Ann Thorac Surg (2012) 0.75
The separation of X-ray diffraction patterns for threat detection. Appl Radiat Isot (2009) 0.75
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. J Heart Lung Transplant (2012) 0.75
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States: executive summary. Circ Heart Fail (2012) 0.75
Position determination of scatter signatures--a novel sensor geometry. Talanta (2010) 0.75
Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States: executive summary. Ann Thorac Surg (2012) 0.75