Published in Birth Defects Res A Clin Mol Teratol on February 09, 2011
The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse. PLoS One (2014) 1.05
Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. Birth Defects Res A Clin Mol Teratol (2012) 0.92
An evolutionarily conserved mechanism of calcium-dependent neurotoxicity in a zebrafish model of fetal alcohol spectrum disorders. Alcohol Clin Exp Res (2014) 0.91
Embryonic alcohol exposure impairs associative learning performance in adult zebrafish. Behav Brain Res (2014) 0.86
Molecular mechanisms of ethanol-associated oro-esophageal squamous cell carcinoma. Cancer Lett (2015) 0.84
Long-term behavioral impairment following acute embryonic ethanol exposure in zebrafish. Neurotoxicol Teratol (2015) 0.83
Transient exposure to ethanol during zebrafish embryogenesis results in defects in neuronal differentiation: an alternative model system to study FASD. PLoS One (2014) 0.83
Molecular and morphological changes in zebrafish following transient ethanol exposure during defined developmental stages. Neurotoxicol Teratol (2014) 0.80
Fishing for Fetal Alcohol Spectrum Disorders: Zebrafish as a Model for Ethanol Teratogenesis. Zebrafish (2016) 0.79
Impairment of social behaviour persists two years after embryonic alcohol exposure in zebrafish: A model of fetal alcohol spectrum disorders. Behav Brain Res (2015) 0.79
Developmental age strengthens barriers to ethanol accumulation in zebrafish. Alcohol (2014) 0.79
Analysis of crosstalk between retinoic acid and sonic hedgehog pathways following ethanol exposure in embryonic zebrafish. Birth Defects Res A Clin Mol Teratol (2015) 0.77
Eye-specific gene expression following embryonic ethanol exposure in zebrafish: roles for heat shock factor 1. Reprod Toxicol (2013) 0.76
Prenatal ethanol exposure phenocopies Cdon mutation by impeding Shh function in the etiology of optic nerve hypoplasia. Dis Model Mech (2016) 0.75
Gene-environment interactions in development and disease. Wiley Interdiscip Rev Dev Biol (2016) 0.75
Comparison of molecular marker expression in early zebrafish brain development following chronic ethanol or morpholino treatment. Exp Brain Res (2017) 0.75
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature (1996) 11.46
Recognition of the fetal alcohol syndrome in early infancy. Lancet (1973) 8.57
Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell (1997) 4.40
Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene. Nat Genet (1992) 3.95
Ethanol effects on the developing zebrafish: neurobehavior and skeletal morphogenesis. Neurotoxicol Teratol (2004) 2.24
Identification of agrin, a synaptic organizing protein from Torpedo electric organ. J Cell Biol (1987) 2.11
Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation. Development (2004) 2.01
Brain malformations related to prenatal exposure to ethanol. J Pediatr (1978) 2.00
Fetal alcohol syndrome: embryogenesis in a mouse model. Science (1981) 1.91
Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways. Development (2004) 1.80
Patterning of the zebrafish retina by a wave of sonic hedgehog activity. Science (2000) 1.77
Effects of acute and chronic ethanol exposure on the behavior of adult zebrafish (Danio rerio). Pharmacol Biochem Behav (2006) 1.77
Acute effects of alcohol on larval zebrafish: a genetic system for large-scale screening. Pharmacol Biochem Behav (2004) 1.75
Fetal alcohol exposure and temporal vulnerability: effects of binge-like alcohol exposure on the developing rat hippocampus. Neurotoxicol Teratol (2003) 1.73
Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process. Development (2004) 1.73
Genesis of alcohol-induced craniofacial dysmorphism. Exp Biol Med (Maywood) (2005) 1.64
Selective vulnerability of embryonic cell populations to ethanol-induced apoptosis: implications for alcohol-related birth defects and neurodevelopmental disorder. Alcohol Clin Exp Res (2001) 1.63
Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina. Development (2005) 1.50
Ethanol exposure alters zebrafish development: a novel model of fetal alcohol syndrome. Neurotoxicol Teratol (2004) 1.48
Strain-dependent effects of developmental ethanol exposure in zebrafish. Neurotoxicol Teratol (2004) 1.45
Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures. Brain Res Dev Brain Res (2005) 1.45
Ethanol effects on three strains of zebrafish: model system for genetic investigations. Pharmacol Biochem Behav (2003) 1.44
Teratogenic effects of ethanol exposure on zebrafish visual system development. Neurotoxicol Teratol (2006) 1.44
Drosophila perlecan modulates FGF and hedgehog signals to activate neural stem cell division. Dev Biol (2003) 1.41
Long-term behavioral changes in response to early developmental exposure to ethanol in zebrafish. Alcohol Clin Exp Res (2009) 1.39
Ethanol impairs migration of the prechordal plate in the zebrafish embryo. Dev Biol (1998) 1.38
Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure. Proc Natl Acad Sci U S A (2002) 1.37
Ethanol- and acetaldehyde-mediated developmental toxicity in zebrafish. Neurotoxicol Teratol (2004) 1.37
Differences in acute alcohol-induced behavioral responses among zebrafish populations. Alcohol Clin Exp Res (2008) 1.35
Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8. Alcohol Clin Exp Res (2009) 1.35
Agrin is a heparan sulfate proteoglycan. J Biol Chem (1995) 1.33
Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 7. Alcohol Clin Exp Res (2009) 1.32
Fetal alcohol exposure impairs Hedgehog cholesterol modification and signaling. Lab Invest (2007) 1.32
Fetal alcohol syndrome and DiGeorge anomaly: critical ethanol exposure periods for craniofacial malformations as illustrated in an animal model. Am J Med Genet Suppl (1986) 1.23
Embryonic origin of holoprosencephaly: interrelationship of the developing brain and face. Scan Electron Microsc (1982) 1.19
Ocular abnormalities in the fetal alcohol syndrome. Acta Ophthalmol Suppl (1985) 1.17
A single day of alcohol exposure during the brain growth spurt induces brain weight restriction and cerebellar Purkinje cell loss. Alcohol (1990) 1.15
Deciphering the role of Shh signaling in axial defects produced by ethanol exposure. Birth Defects Res A Clin Mol Teratol (2009) 1.11
Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway. Mol Cancer (2006) 1.08
Perlecan controls neurogenesis in the developing telencephalon. BMC Dev Biol (2007) 1.08
Fgf19 regulated by Hh signaling is required for zebrafish forebrain development. Dev Biol (2005) 1.07
Effects of ethanol on photoreceptors and visual function in developing zebrafish. Invest Ophthalmol Vis Sci (2006) 1.05
Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of Hedgehog. Dev Biol (2005) 1.03
Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin. Dev Biol (2006) 1.02
Fetal ethanol exposure activates protein kinase A and impairs Shh expression in prechordal mesendoderm cells in the pathogenesis of holoprosencephaly. Birth Defects Res A Clin Mol Teratol (2008) 1.02
The heparan sulfate proteoglycan agrin modulates neurite outgrowth mediated by FGF-2. J Neurobiol (2003) 1.02
The homeobox gene mbx is involved in eye and tectum development. Dev Biol (2002) 1.00
Ethanol exposure during embryogenesis decreases the radial glial progenitorpool and affects the generation of neurons and astrocytes. J Neurosci Res (2006) 0.99
Hindbrain and cranial nerve dysmorphogenesis result from acute maternal ethanol administration. Dev Neurosci (2002) 0.99
Hearing disorders in children with fetal alcohol syndrome: findings from case reports. Pediatrics (1988) 0.98
Molecular changes associated with teratogen-induced cyclopia. Birth Defects Res A Clin Mol Teratol (2007) 0.97
Hearing, speech, language, and vestibular disorders in the fetal alcohol syndrome: a literature review. Alcohol Clin Exp Res (1997) 0.97
Mechanisms for persistent microphthalmia following ethanol exposure during retinal neurogenesis in zebrafish embryos. Vis Neurosci (2007) 0.95
Sequential and cooperative action of Fgfs and Shh in the zebrafish retina. Dev Biol (2007) 0.95
Ocular deficits associated with alcohol exposure during zebrafish development. J Comp Neurol (2007) 0.94
Ocular manifestations in fetal alcohol syndrome. Br J Ophthalmol (1991) 0.93
Prenatal ethanol exposure during the last third of gestation in rat reduces hippocampal NMDA agonist binding site density in 45-day-old offspring. Alcohol (1992) 0.92
Fetal alcohol exposure and temporal vulnerability regional differences in alcohol-induced microencephaly as a function of the timing of binge-like alcohol exposure during rat brain development. Alcohol Clin Exp Res (1997) 0.92
Brain malformations in prenatal mice following acute maternal ethanol administration. Int J Dev Neurosci (1984) 0.91
Agrin in the CNS: a protein in search of a function? Neuroreport (2002) 0.91
Agrin is required for posterior development and motor axon outgrowth and branching in embryonic zebrafish. Glycobiology (2006) 0.90
Optic nerve hypoplasia: comparative effects in children and rats exposed to alcohol during pregnancy. Teratology (1994) 0.87
Purkinje cell deficits in nonhuman primates following weekly exposure to ethanol during gestation. Teratology (1996) 0.87
Gene expression changes in developing zebrafish as potential markers for rapid developmental neurotoxicity screening. Neurotoxicol Teratol (2009) 0.86
A critical role of Pax6 in alcohol-induced fetal microcephaly. Neurobiol Dis (2004) 0.86
Retina development in zebrafish requires the heparan sulfate proteoglycan agrin. Dev Neurobiol (2008) 0.85
Glutamate and GABA receptor dysfunction in the fetal alcohol syndrome. Neurotox Res (2002) 0.85
Natural loss of Purkinje cells during development and increased loss with alcohol. Brain Res (1985) 0.83
Morphometric analysis of the postnatal mouse optic nerve following prenatal exposure to alcohol. J Anat (1997) 0.83
Specific effects of ethanol on neurite-promoting proteoglycans of neuronal origin. Brain Res (1990) 0.82
Alterations of mouse embryonic branchial nerves and ganglia induced by ethanol. Neurotoxicol Teratol (1995) 0.80
Ethanol decreases agrin-induced acetylcholine receptor clustering in C2C12 myotube culture. Toxicol In Vitro (2009) 0.77
Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis. Mol Genet Metab (2006) 1.77
Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse. Development (2002) 1.49
Nrf2-mediated transcriptional induction of antioxidant response in mouse embryos exposed to ethanol in vivo: implications for the prevention of fetal alcohol spectrum disorders. Antioxid Redox Signal (2008) 1.38
Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8. Alcohol Clin Exp Res (2009) 1.35
Reprogramming of genetic networks during initiation of the Fetal Alcohol Syndrome. Dev Dyn (2007) 1.34
Magnetic resonance microscopy defines ethanol-induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 7. Alcohol Clin Exp Res (2009) 1.32
Biomechanical properties of native basement membranes. FEBS J (2007) 1.31
Differential effects of ethanol antagonism and neuroprotection in peptide fragment NAPVSIPQ prevention of ethanol-induced developmental toxicity. Proc Natl Acad Sci U S A (2003) 1.23
Assembly of lamina-specific neuronal connections by slit bound to type IV collagen. Cell (2011) 1.22
Maternal oral intake mouse model for fetal alcohol spectrum disorders: ocular defects as a measure of effect. Alcohol Clin Exp Res (2006) 1.18
Ethanol-induced face-brain dysmorphology patterns are correlative and exposure-stage dependent. PLoS One (2012) 1.17
Abnormal cortical thickness alterations in fetal alcohol spectrum disorders and their relationships with facial dysmorphology. Cereb Cortex (2011) 1.15
Peptide-mediated protection from ethanol-induced neural tube defects. Dev Neurosci (2005) 1.07
Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications. Birth Defects Res A Clin Mol Teratol (2010) 1.06
Magnetic resonance microscopy-based analyses of the brains of normal and ethanol-exposed fetal mice. Birth Defects Res A Clin Mol Teratol (2010) 1.06
Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish. Mech Dev (2007) 1.06
Regional brain volume reductions relate to facial dysmorphology and neurocognitive function in fetal alcohol spectrum disorders. Hum Brain Mapp (2011) 1.05
Association of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain. J Neuroimmunol (2002) 1.04
The heparan sulfate proteoglycan agrin modulates neurite outgrowth mediated by FGF-2. J Neurobiol (2003) 1.02
Protection from ethanol-induced limb malformations by the superoxide dismutase/catalase mimetic, EUK-134. FASEB J (2004) 1.02
Callosal thickness reductions relate to facial dysmorphology in fetal alcohol spectrum disorders. Alcohol Clin Exp Res (2011) 1.00
Magnetic resonance-based imaging in animal models of fetal alcohol spectrum disorder. Neuropsychol Rev (2011) 0.99
Hindbrain and cranial nerve dysmorphogenesis result from acute maternal ethanol administration. Dev Neurosci (2002) 0.99
Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters. J Biol Chem (2003) 0.99
Induction of the Nrf2-driven antioxidant response by tert-butylhydroquinone prevents ethanol-induced apoptosis in cranial neural crest cells. Biochem Pharmacol (2010) 0.98
The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos. Toxicol Lett (2009) 0.98
Genesis of teratogen-induced holoprosencephaly in mice. Am J Med Genet C Semin Med Genet (2010) 0.97
Age-dependent changes in the structure, composition and biophysical properties of a human basement membrane. Matrix Biol (2010) 0.96
Embryonic synthesis of the inner limiting membrane and vitreous body. Invest Ophthalmol Vis Sci (2005) 0.93
Ventromedian forebrain dysgenesis follows early prenatal ethanol exposure in mice. Neurotoxicol Teratol (2010) 0.93
Perturbation of retinoic acid (RA)-mediated limb development suggests a role for diminished RA signaling in the teratogenesis of ethanol. Birth Defects Res A Clin Mol Teratol (2007) 0.92
Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. Birth Defects Res A Clin Mol Teratol (2012) 0.92
Concurrent dietary administration of D-SAL and ethanol diminishes ethanol's teratogenesis. Alcohol Clin Exp Res (2007) 0.91
Agrin is required for posterior development and motor axon outgrowth and branching in embryonic zebrafish. Glycobiology (2006) 0.90
Ethanol antagonist peptides: structural specificity without stereospecificity. J Pharmacol Exp Ther (2004) 0.89
Transitin, a nestin-like intermediate filament protein, mediates cortical localization and the lateral transport of Numb in mitotic avian neuroepithelial cells. Development (2007) 0.87
Mitogen-activated protein kinase modulates ethanol inhibition of cell adhesion mediated by the L1 neural cell adhesion molecule. Proc Natl Acad Sci U S A (2013) 0.87
Generation of transgenic zebrafish expressing green fluorescent protein under control of zebrafish amyloid precursor protein gene regulatory elements. Zebrafish (2007) 0.87
Retina development in zebrafish requires the heparan sulfate proteoglycan agrin. Dev Neurobiol (2008) 0.85
Magnetic resonance microscopy-based analyses of the neuroanatomical effects of gestational day 9 ethanol exposure in mice. Neurotoxicol Teratol (2013) 0.83
Agrin binds alpha-synuclein and modulates alpha-synuclein fibrillation. Glycobiology (2005) 0.83
Zebrafish K5 promoter driven GFP expression as a transgenic system for oral research. Oral Oncol (2009) 0.83
A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high. PLoS One (2010) 0.83
Expression of collagen XVIII and localization of its glycosaminoglycan attachment sites. J Biol Chem (2002) 0.82
Dysmorphogenic effects of first trimester-equivalent ethanol exposure in mice: a magnetic resonance microscopy-based study. Alcohol Clin Exp Res (2014) 0.80
Reduction of ethanol-induced ocular abnormalities in mice through dietary administration of N-acetylcysteine. Alcohol (2010) 0.78
Transgenic overexpression of cdx1b induces metaplastic changes of gene expression in zebrafish esophageal squamous epithelium. Zebrafish (2013) 0.75
Continuing education course #3: current practices and future trends in neuropathology assessment for developmental neurotoxicity testing. Toxicol Pathol (2010) 0.75
Focus on: magnetic resonance-based studies of fetal alcohol spectrum disorders in animal models. Alcohol Res Health (2011) 0.75
Transitin is required for the differentiation of avian QM7 myoblasts into myotubes. Dev Dyn (2010) 0.75