Published in Biochimie on September 01, 2002
Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat Struct Mol Biol (2005) 2.50
Selenium derivatization and crystallization of DNA and RNA oligonucleotides for X-ray crystallography using multiple anomalous dispersion. Nucleic Acids Res (2004) 1.09
Selenium derivatization of nucleic acids for crystallography. Nucleic Acids Res (2006) 0.99
Derivatization of DNAs with selenium at 6-position of guanine for function and crystal structure studies. Nucleic Acids Res (2008) 0.98
Efficient substrate cleavage catalyzed by hammerhead ribozymes derivatized with selenium for X-ray crystallography. Biochemistry (2006) 0.94
A fast selenium derivatization strategy for crystallization and phasing of RNA structures. RNA (2009) 0.91
Synthesis of a 2'-Se-thymidine phosphoramidite and its incorporation into oligonucleotides for crystal structure study. Org Lett (2007) 0.91
Crystallographic studies of chemically modified nucleic acids: a backward glance. Chem Biodivers (2010) 0.86
2'-Methylseleno-modified oligoribonucleotides for X-ray crystallography synthesized by the ACE RNA solid-phase approach. Nucleic Acids Res (2007) 0.85
A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution. Chem Commun (Camb) (2009) 0.84
Selenium derivatization of nucleic acids for phase and structure determination in nucleic acid X-ray crystallography. Int J Mol Sci (2008) 0.84
Synthesis of a 2'-Se-uridine phosphoramidite and its incorporation into oligonucleotides for structural study. Org Lett (2005) 0.84
Crystallization and X-ray diffraction analysis of the Trp/amber editing site of hepatitis delta virus (+)RNA: a case of rational design. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.78
Nucleic-acid structural deformability deduced from anisotropic displacement parameters. Biopolymers (2010) 0.77
Two-dimensional x-ray correlation spectroscopy of remote core states. Struct Dyn (2013) 0.76
Structural basis for the function and inhibition of an influenza virus proton channel. Nature (2008) 5.69
Adjustment of systematic microarray data biases. Bioinformatics (2004) 5.22
Thrombin-receptor antagonist vorapaxar in acute coronary syndromes. N Engl J Med (2011) 3.20
Adjunctive counseling during brief and extended buprenorphine-naloxone treatment for prescription opioid dependence: a 2-phase randomized controlled trial. Arch Gen Psychiatry (2011) 3.15
The dragon strikes: lessons from the Wenchuan earthquake. Anesth Analg (2010) 2.78
Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins. Proc Natl Acad Sci U S A (2006) 2.66
Visualizing a circadian clock protein: crystal structure of KaiC and functional insights. Mol Cell (2004) 2.54
Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat Struct Mol Biol (2005) 2.50
Identification of key phosphorylation sites in the circadian clock protein KaiC by crystallographic and mutagenetic analyses. Proc Natl Acad Sci U S A (2004) 2.43
Crystal structure of full-length KcsA in its closed conformation. Proc Natl Acad Sci U S A (2009) 2.35
Elucidating the ticking of an in vitro circadian clockwork. PLoS Biol (2007) 2.19
High-affinity single-domain binding proteins with a binary-code interface. Proc Natl Acad Sci U S A (2007) 2.18
DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine. J Biol Chem (2005) 2.02
Racial variation in quality of care among Medicare+Choice enrollees. Health Aff (Millwood) (2002) 1.82
Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4. J Biol Chem (2005) 1.74
A multi-site, two-phase, Prescription Opioid Addiction Treatment Study (POATS): rationale, design, and methodology. Contemp Clin Trials (2010) 1.72
Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi. J Biol Chem (2010) 1.71
Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis. Nat Chem Biol (2006) 1.68
X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers. J Am Chem Soc (2008) 1.64
"Wide-open" 1.3 A structure of a multidrug-resistant HIV-1 protease as a drug target. Structure (2005) 1.63
Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections. J Biol Chem (2009) 1.60
Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods. EMBO J (2006) 1.59
Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets. Structure (2003) 1.56
Effect of vorapaxar on myocardial infarction in the thrombin receptor antagonist for clinical event reduction in acute coronary syndrome (TRA·CER) trial. Eur Heart J (2013) 1.56
A business case for shared medical appointments in dermatology: improving access and the bottom line. Arch Dermatol (2010) 1.53
Synthetic antibodies for specific recognition and crystallization of structured RNA. Proc Natl Acad Sci U S A (2007) 1.51
Racial analysis of patients with myocardial infarction complicated by heart failure and/or left ventricular dysfunction treated with valsartan, captopril, or both. J Am Coll Cardiol (2008) 1.48
Structure of the TDP-epi-vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway. Proc Natl Acad Sci U S A (2003) 1.45
Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization. Angew Chem Int Ed Engl (2006) 1.45
Crystal structures of a multidrug-resistant human immunodeficiency virus type 1 protease reveal an expanded active-site cavity. J Virol (2004) 1.40
Simultaneous catalytic removal of NOx and diesel PM over La(0.9) K(0.1) CoO3 catalyst assisted by plasma. J Environ Sci (China) (2005) 1.39
The cyanobacterial circadian system: from biophysics to bioevolution. Annu Rev Biophys (2011) 1.39
Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4. J Biol Chem (2007) 1.38
An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples. FEBS J (2010) 1.36
Racial variation in the control of diabetes among elderly medicare managed care beneficiaries. Diabetes Care (2003) 1.35
Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide. ACS Chem Biol (2006) 1.33
A human-specific de novo protein-coding gene associated with human brain functions. PLoS Comput Biol (2010) 1.31
Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct. J Biol Chem (2009) 1.31
Structural insights into a circadian oscillator. Science (2008) 1.30
Enhanced gene delivery and siRNA silencing by gold nanoparticles coated with charge-reversal polyelectrolyte. ACS Nano (2010) 1.29
Substrate preferences and catalytic parameters determined by structural characteristics of sterol 14alpha-demethylase (CYP51) from Leishmania infantum. J Biol Chem (2011) 1.29
Vesicular zinc promotes presynaptic and inhibits postsynaptic long-term potentiation of mossy fiber-CA3 synapse. Neuron (2011) 1.29
Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA. Nucleic Acids Res (2010) 1.28
Sulfolobus solfataricus DNA polymerase Dpo4 is partially inhibited by "wobble" pairing between O6-methylguanine and cytosine, but accurate bypass is preferred. J Biol Chem (2006) 1.22
Does Medicare managed care provide equal treatment for mental illness across races? Arch Gen Psychiatry (2004) 1.21
Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs. Nucleic Acids Res (2009) 1.21
Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods. Protein Sci (2009) 1.20
Selecting aptamers for a glycoprotein through the incorporation of the boronic acid moiety. J Am Chem Soc (2008) 1.20
Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs. Angew Chem Int Ed Engl (2011) 1.20
Internal derivatization of oligonucleotides with selenium for X-ray crystallography using MAD. J Am Chem Soc (2002) 1.20
MALAT-1 interacts with hnRNP C in cell cycle regulation. FEBS Lett (2013) 1.19
Structural model of the circadian clock KaiB-KaiC complex and mechanism for modulation of KaiC phosphorylation. EMBO J (2008) 1.19
Antitrypanosomal lead discovery: identification of a ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth. J Med Chem (2013) 1.19
Complexes of Trypanosoma cruzi sterol 14α-demethylase (CYP51) with two pyridine-based drug candidates for Chagas disease: structural basis for pathogen selectivity. J Biol Chem (2013) 1.18
Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain. Protein Sci (2004) 1.17
Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene. J Biol Chem (2007) 1.16
Clinical characteristics and long-term outcome of patients with POEMS syndrome in China. Ann Hematol (2011) 1.16
Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice. Mol Ther (2011) 1.16
Overexpression of cyclin B1 in human esophageal squamous cell carcinoma cells induces tumor cell invasive growth and metastasis. Carcinogenesis (2007) 1.16
Analysis of siRNA specificity on targets with double-nucleotide mismatches. Nucleic Acids Res (2008) 1.14
Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope. J Mol Biol (2007) 1.13
Chronic obstructive pulmonary disease is an independent predictor of death but not atherosclerotic events in patients with myocardial infarction: analysis of the Valsartan in Acute Myocardial Infarction Trial (VALIANT). Eur J Heart Fail (2009) 1.13
Distortion-dependent unhooking of interstrand cross-links in mammalian cell extracts. Biochemistry (2008) 1.13
Oxygen replacement with selenium at the thymidine 4-position for the Se base pairing and crystal structure studies. J Am Chem Soc (2007) 1.13
Intramolecular regulation of phosphorylation status of the circadian clock protein KaiC. PLoS One (2009) 1.12
An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury. Bioorg Med Chem Lett (2003) 1.11
Selenium-assisted nucleic acid crystallography: use of phosphoroselenoates for MAD phasing of a DNA structure. J Am Chem Soc (2002) 1.11
Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme. Nucleic Acids Res (2007) 1.11
A molecular force probe. Nat Nanotechnol (2009) 1.10
Structure of bistramide A-actin complex at a 1.35 angstroms resolution. J Am Chem Soc (2006) 1.10
Pentameric assembly of potassium channel tetramerization domain-containing protein 5. J Mol Biol (2009) 1.10
GluR3 flip and flop: differences in channel opening kinetics. Biochemistry (2007) 1.10
Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineering. Protein Sci (2006) 1.10
Interdomain allostery promotes assembly of the poly(A) mRNA complex with PABP and eIF4G. Mol Cell (2012) 1.10
Preparation of interstrand cross-linked DNA oligonucleotide duplexes. Front Biosci (2004) 1.09
Structures of KaiC circadian clock mutant proteins: a new phosphorylation site at T426 and mechanisms of kinase, ATPase and phosphatase. PLoS One (2009) 1.09
Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA. Nucleic Acids Res (2007) 1.09
Selenium derivatization and crystallization of DNA and RNA oligonucleotides for X-ray crystallography using multiple anomalous dispersion. Nucleic Acids Res (2004) 1.09
Gli3 null mice display glandular overgrowth of the developing stomach. Dev Dyn (2005) 1.08
N(4)C-ethyl-N(4)C cross-linked DNA: synthesis and characterization of duplexes with interstrand cross-links of different orientations. Biochemistry (2002) 1.07
High fidelity of base pairing by 2-selenothymidine in DNA. J Am Chem Soc (2010) 1.07
Anxiety and depression in patients with liver cirrhosis. Radiology (2013) 1.07
Epiglottic dysfunction: abnormal epiglottic movement patterns. Dysphagia (2002) 1.07
Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA. J Am Chem Soc (2009) 1.07
Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system. J Am Chem Soc (2006) 1.06
Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs. Biochem Biophys Res Commun (2003) 1.06
Combined SAXS/EM based models of the S. elongatus post-translational circadian oscillator and its interactions with the output His-kinase SasA. PLoS One (2011) 1.05
Ultrasound-guided percutaneous endovascular aneurysm repair success is predicted by access vessel diameter. J Vasc Surg (2012) 1.05
Comparison of opiate-primary treatment seekers with and without alcohol use disorder. J Subst Abuse Treat (2010) 1.05
Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Delta7-24, 25-dihydrolanosterol. J Lipid Res (2011) 1.04
Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2. Nat Struct Mol Biol (2007) 1.04
Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants. Acta Crystallogr D Biol Crystallogr (2011) 1.04