Published in Oncogene on December 16, 2002
Oxidative stress, cell cycle, and neurodegeneration. J Clin Invest (2003) 1.84
DNA replication fidelity and cancer. Semin Cancer Biol (2010) 1.69
Constitutive histone H2AX phosphorylation and ATM activation are strongly amplified during mitogenic stimulation of lymphocytes. Cell Prolif (2007) 1.33
The Role of PPARs in Cancer. PPAR Res (2008) 1.26
Functional study of the P32T ITPA variant associated with drug sensitivity in humans. J Mol Biol (2009) 1.23
Gingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalis. Front Biosci (2008) 1.20
Mammalian enzymes for preventing transcriptional errors caused by oxidative damage. Nucleic Acids Res (2005) 1.18
DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine. Mutat Res (2010) 1.18
Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2. J Biol Chem (2012) 1.15
A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides. EMBO Rep (2003) 1.14
The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. Mol Cell Biol (2005) 1.14
A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome. Genome Res (2006) 1.06
Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis. J Bacteriol (2006) 1.04
Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis. Plant Physiol (2008) 1.02
Chronic exposure to the cytolethal distending toxins of Gram-negative bacteria promotes genomic instability and altered DNA damage response. Cell Microbiol (2012) 1.00
Quercitrin protects skin from UVB-induced oxidative damage. Toxicol Appl Pharmacol (2013) 0.99
Measurement of 7,8-dihydro-8-oxo-2'-deoxyguanosine metabolism in MCF-7 cells at low concentrations using accelerator mass spectrometry. Proc Natl Acad Sci U S A (2007) 0.97
Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine . Biochemistry (2010) 0.96
Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools. Environ Mol Mutagen (2012) 0.93
Tumor hypoxia and genetic alterations in sporadic cancers. J Obstet Gynaecol Res (2011) 0.93
Mycobacterial MazG is a novel NTP pyrophosphohydrolase involved in oxidative stress response. J Biol Chem (2010) 0.93
Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2. J Biol Chem (2009) 0.92
MnSOD upregulation induces autophagic programmed cell death in senescent keratinocytes. PLoS One (2010) 0.91
Critical amino acids in human DNA polymerases eta and kappa involved in erroneous incorporation of oxidized nucleotides. Nucleic Acids Res (2009) 0.91
Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains. Mol Microbiol (2012) 0.89
Inflammation-induced cell proliferation potentiates DNA damage-induced mutations in vivo. PLoS Genet (2015) 0.88
Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP and dGMP to be inserted opposite Guanidinohydantoin . Biochemistry (2010) 0.88
DNA repair of 8-oxo-7,8-dihydroguanine lesions in Porphyromonas gingivalis. J Bacteriol (2008) 0.87
Nutritional countermeasures targeting reactive oxygen species in cancer: from mechanisms to biomarkers and clinical evidence. Antioxid Redox Signal (2013) 0.86
A highly conserved Tyrosine residue of family B DNA polymerases contributes to dictate translesion synthesis past 8-oxo-7,8-dihydro-2'-deoxyguanosine. Nucleic Acids Res (2007) 0.86
Incorporation of extracellular 8-oxodG into DNA and RNA requires purine nucleoside phosphorylase in MCF-7 cells. Nucleic Acids Res (2007) 0.84
8-Hydroxyguanine in a mutational hotspot of the c-Ha-ras gene causes misreplication, 'action-at-a-distance' mutagenesis and inhibition of replication. Nucleic Acids Res (2003) 0.82
Monitoring repair of DNA damage in cell lines and human peripheral blood mononuclear cells. Anal Biochem (2007) 0.81
[Genetic control of metabolism of mutagenic purine base analogs 6-hydroxylaminopurine and 2-amino-6-hydroxylaminopurine in yeast Saccharomyces cerevisiae]. Genetika (2009) 0.81
Elimination and utilization of oxidized guanine nucleotides in the synthesis of RNA and its precursors. J Biol Chem (2013) 0.80
The Impact of Non-Enzymatic Reactions and Enzyme Promiscuity on Cellular Metabolism during (Oxidative) Stress Conditions. Biomolecules (2015) 0.79
Mycobacterial MazG safeguards genetic stability via housecleaning of 5-OH-dCTP. PLoS Pathog (2013) 0.79
Search for proteins required for accurate gene expression under oxidative stress: roles of guanylate kinase and RNA polymerase. J Biol Chem (2013) 0.79
What causes human cancer? Approaches from the chemistry of DNA damage. Genes Environ (2016) 0.78
UV radiation induces delayed hyperrecombination associated with hypermutation in human cells. Mol Cell Biol (2006) 0.78
Nucleotides function as endogenous chemical sensors for oxidative stress signaling. J Clin Biochem Nutr (2010) 0.77
Protective role of the PG1036-PG1037-PG1038 operon in oxidative stress in Porphyromonas gingivalis W83. PLoS One (2013) 0.77
An increase of oxidised nucleotides activates DNA damage checkpoint pathway that regulates post-embryonic development in Caenorhabditis elegans. Mutagenesis (2014) 0.76
Mutations induced by 8-hydroxyguanine (8-oxo-7,8-dihydroguanine), a representative oxidized base, in mammalian cells. Genes Environ (2016) 0.75
Role of Bacillus subtilis error prevention oxidized guanine system in counteracting hexavalent chromium-promoted oxidative DNA damage. Appl Environ Microbiol (2014) 0.75
Production, Purification, and Characterization of (15)N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements. Methods Enzymol (2015) 0.75
Chenodeoxycholic Acid Derivative HS-1200 Inhibits Hepatocarcinogenesis and Improves Liver Function in Diethylnitrosamine-Exposed Rats by Downregulating MTH1. Biomed Res Int (2017) 0.75
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair. Nat Commun (2017) 0.75
De Novo Emergence of Genetically Resistant Mutants of Mycobacterium tuberculosis from the Persistence Phase Cells formed against Antituberculosis Drugs In Vitro. Antimicrob Agents Chemother (2016) 0.75
Biochemical behavior of N-oxidized cytosine and adenine bases in DNA polymerase-mediated primer extension reactions. Nucleic Acids Res (2011) 0.75
Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption. Cancer Res (2003) 1.75
Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice. Arterioscler Thromb Vasc Biol (2004) 1.70
Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids. Biol Chem (2006) 1.59
Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling. Circ Res (2004) 1.57
MUTYH-null mice are susceptible to spontaneous and oxidative stress induced intestinal tumorigenesis. Cancer Res (2007) 1.30
YB-1 is important for an early stage embryonic development: neural tube formation and cell proliferation. J Biol Chem (2006) 1.12
Measles virus infection of SLAM (CD150) knockin mice reproduces tropism and immunosuppression in human infection. J Virol (2006) 1.02
The role of P-glycoprotein in intestinal tumorigenesis: disruption of mdr1a suppresses polyp formation in Apc(Min/+) mice. Carcinogenesis (2003) 0.99
Mutational specificity of mice defective in the MTH1 and/or the MSH2 genes. DNA Repair (Amst) (2002) 0.95
Two modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability. Nucleic Acids Res (2005) 0.95
Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base. J Biol Chem (2009) 0.93
Targeted disruption of one allele of the Y-box binding protein-1 (YB-1) gene in mouse embryonic stem cells and increased sensitivity to cisplatin and mitomycin C. Cancer Sci (2004) 0.93
Activation of AMP-activated protein kinase by MAPO1 and FLCN induces apoptosis triggered by alkylated base mismatch in DNA. DNA Repair (Amst) (2011) 0.85
Modes of actions of two types of anti-neoplastic drugs, dacarbazine and ACNU, to induce apoptosis. Carcinogenesis (2007) 0.81
DNA repair dysfunction in gastrointestinal tract cancers. Cancer Sci (2008) 0.78
Improved gene correction efficiency with a tailed duplex DNA fragment. Biochemistry (2008) 0.77
Oxidative stress-induced tumorigenesis in the small intestines of DNA repair-deficient mice. Health Phys (2011) 0.76
Correction: PSMC5, a 19S proteasomal ATPase, regulates cocaine action in the nucleus accumbens. PLoS One (2015) 0.75
Effects of target sequence and sense versus anti-sense strands on gene correction with single-stranded DNA fragments. J Biochem (2008) 0.75
Targeted sequence alteration of a chromosomal locus in mouse liver. Int J Pharm (2009) 0.75
Orpheus recombination : a comprehensive bacteriophage system for murine targeting vector construction by transplacement. Methods Mol Biol (2008) 0.75