Published in Int Rev Immunol on December 18, 2002
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Toxoplasma gondii-specific immunoglobulin M limits parasite dissemination by preventing host cell invasion. Infect Immun (2005) 0.86
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Altered endochondral ossification in collagen X mouse models leads to impaired immune responses. Dev Dyn (2008) 0.78
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Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat Immunol (2006) 7.89
Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science (2003) 7.75
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol (2007) 5.99
The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity (2003) 5.60
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Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J Clin Invest (2006) 4.77
Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science (2008) 4.04
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The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology. Immunity (2012) 2.52
Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1. Immunity (2012) 2.47
IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells. J Immunol (2009) 2.39
Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells. Nature (2012) 2.38
IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12. J Immunol (2004) 2.37
TRAF6 is a critical factor for dendritic cell maturation and development. Immunity (2003) 2.36
Helminth antigens modulate TLR-initiated dendritic cell activation. J Immunol (2004) 2.21
Trafficking of immune cells in the central nervous system. J Clin Invest (2010) 2.17
The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity. J Immunol (2004) 2.09
A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8⁺ T-cell accumulation in the skin. J Invest Dermatol (2012) 2.05
NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions. Clin Microbiol Rev (2002) 1.97
IL-27 limits IL-2 production during Th1 differentiation. J Immunol (2006) 1.89
A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis. J Neuroimmunol (2005) 1.86
Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesis-associated system of reticular fibers. Immunity (2009) 1.84
Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation. J Immunol (2011) 1.84
Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals. J Exp Med (2007) 1.83
Understanding the pro- and anti-inflammatory properties of IL-27. J Immunol (2004) 1.74
A critical role for SOCS3 in innate resistance to Toxoplasma gondii. Cell Host Microbe (2011) 1.70
Pivotal advance: peritoneal cavity B-1 B cells have phagocytic and microbicidal capacities and present phagocytosed antigen to CD4+ T cells. J Leukoc Biol (2011) 1.67
The composition and signaling of the IL-35 receptor are unconventional. Nat Immunol (2012) 1.63
Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation. Cell Host Microbe (2011) 1.62
New directions in the basic and translational biology of interleukin-27. Trends Immunol (2011) 1.54
Early enhanced Th1 response after Leishmania amazonensis infection of C57BL/6 interleukin-10-deficient mice does not lead to resolution of infection. Infect Immun (2002) 1.54
Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. Proc Natl Acad Sci U S A (2013) 1.54
An essential role of Th1 responses and interferon gamma in infection-mediated suppression of neoplastic growth. Cancer Biol Ther (2003) 1.52
CXCL10 is critical for the progression and maintenance of depigmentation in a mouse model of vitiligo. Sci Transl Med (2014) 1.50
Positive and negative regulation of the IL-27 receptor during lymphoid cell activation. J Immunol (2005) 1.48
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An AAAA–DDDD quadruple hydrogen-bond array. Nat Chem (2011) 1.47
STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis. J Immunol (2004) 1.47
IL-27 regulates IL-10 and IL-17 from CD4+ cells in nonhealing Leishmania major infection. J Immunol (2009) 1.46
Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines. J Immunol (2008) 1.45
A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat Immunol (2010) 1.44
T cell expression of MyD88 is required for resistance to Toxoplasma gondii. Proc Natl Acad Sci U S A (2008) 1.43
Immune response and immunopathology during toxoplasmosis. Semin Immunopathol (2012) 1.38
Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii. PLoS Pathog (2009) 1.37
IL-6 promotes NK cell production of IL-17 during toxoplasmosis. J Immunol (2010) 1.35
IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. J Immunol (2012) 1.34
Sequence-dependent DNA structure: a database of octamer structural parameters. J Mol Biol (2003) 1.33
Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation. J Immunol (2002) 1.31
The immunobiology of IL-27. Adv Immunol (2012) 1.30
Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection. J Immunol (2010) 1.29
TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development. J Immunol (2005) 1.27
Presentation of Toxoplasma gondii antigens via the endogenous major histocompatibility complex class I pathway in nonprofessional and professional antigen-presenting cells. Infect Immun (2007) 1.26
Dendritic cells distinguish individual chemokine signals through CCR7 and CXCR4. J Immunol (2010) 1.25
T cell-intrinsic expression of c-Rel regulates Th1 cell responses essential for resistance to Toxoplasma gondii. J Immunol (2004) 1.23
Synthesis of a molecular trefoil knot by folding and closing on an octahedral coordination template. Nat Chem (2010) 1.22
Development of a system to study CD4+-T-cell responses to transgenic ovalbumin-expressing Toxoplasma gondii during toxoplasmosis. Infect Immun (2004) 1.21
IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis. J Immunol (2009) 1.21
Toxoplasma co-opts host cells it does not invade. PLoS Pathog (2012) 1.21
Chemical double-mutant cycles: dissecting non-covalent interactions. Chem Soc Rev (2006) 1.18
Cutting edge: identification of c-Rel-dependent and -independent pathways of IL-12 production during infectious and inflammatory stimuli. J Immunol (2002) 1.18
The immunobiology of interleukin-27. Annu Rev Immunol (2015) 1.18
A role for IL-27 in limiting T regulatory cell populations. J Immunol (2011) 1.17
Cutting Edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter. J Immunol (2004) 1.16
Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection. J Immunol (2004) 1.16
Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia. J Biol Chem (2002) 1.14
Dendritic cells and immunity to leishmaniasis and toxoplasmosis. Curr Opin Immunol (2002) 1.11
Act1-ivating IL-17 inflammation. Nat Immunol (2007) 1.11
Toll-like receptor 4 contributes to poor outcome after intracerebral hemorrhage. Ann Neurol (2011) 1.11
Two distinct activation states of plasmacytoid dendritic cells induced by influenza virus and CpG 1826 oligonucleotide. J Leukoc Biol (2007) 1.11
Regulatory pathways involved in the infection-induced production of IFN-gamma by NK cells. Microbes Infect (2002) 1.10
Kinetics and phenotype of vaccine-induced CD8+ T-cell responses to Toxoplasma gondii. Infect Immun (2009) 1.10
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Cutting edge: NF-kappa B2 is a negative regulator of dendritic cell function. J Immunol (2004) 1.09
Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells. J Immunol (2010) 1.07
The role of astrocytes in the immunopathogenesis of toxoplasmic encephalitis. Int J Parasitol (2004) 1.07
IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals. PLoS Pathog (2013) 1.06
Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies. J Clin Invest (2016) 1.05
Initiation and termination of NF-kappaB signaling by the intracellular protozoan parasite Toxoplasma gondii. J Cell Sci (2005) 1.04
Regulation of CD8+ T cell responses to infection with parasitic protozoa. Exp Parasitol (2010) 1.04
T cell heterogeneity: firmly fixed, predominantly plastic or merely malleable? Nat Immunol (2008) 1.02
Contribution of interleukin-12 (IL-12) and the CD28/B7 and CD40/CD40 ligand pathways to the development of a pathological T-cell response in IL-10-deficient mice. Infect Immun (2002) 1.01
Inhibition of NF-kappa B activity in T and NK cells results in defective effector cell expansion and production of IFN-gamma required for resistance to Toxoplasma gondii. J Immunol (2003) 1.01
Opposing roles of NF-kappaB family members in the regulation of NK cell proliferation and production of IFN-gamma. Int Immunol (2006) 1.01
Susceptibility of interleukin-2-deficient mice to Toxoplasma gondii is associated with a defect in the production of gamma interferon. Infect Immun (2002) 1.01
Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J (2010) 1.01
Toxoplasma gondii and schizophrenia: linkage through astrocyte-derived kynurenic acid? Schizophr Bull (2007) 1.00
New lessons from old pathogens: what parasitic infections have taught us about the role of nuclear factor-kappaB in the regulation of immunity. Immunol Rev (2004) 0.99
Neutrophil depletion diminishes monocyte infiltration and improves functional outcome after experimental intracerebral hemorrhage. Acta Neurochir Suppl (2011) 0.99
Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15. Infect Immun (2013) 0.98
TRAF6-dependent mitogen-activated protein kinase activation differentially regulates the production of interleukin-12 by macrophages in response to Toxoplasma gondii. Infect Immun (2004) 0.97
IL-30 (IL27p28) attenuates liver fibrosis through inducing NKG2D-rae1 interaction between NKT and activated hepatic stellate cells in mice. Hepatology (2014) 0.97
NF-kappa B2 is required for optimal CD40-induced IL-12 production but dispensable for Th1 cell Differentiation. J Immunol (2002) 0.97
NF-kappa B1 is required for optimal CD4+ Th1 cell development and resistance to Leishmania major. J Immunol (2003) 0.96
IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD. Int Immunol (2008) 0.95
Host cell Ca2+ and protein kinase C regulate innate recognition of Toxoplasma gondii. J Cell Sci (2006) 0.95
CXCL10 is required to maintain T-cell populations and to control parasite replication during chronic ocular toxoplasmosis. Invest Ophthalmol Vis Sci (2011) 0.95
B7RP-1-ICOS interactions are required for optimal infection-induced expansion of CD4+ Th1 and Th2 responses. J Immunol (2006) 0.94
Measuring traction forces of motile dendritic cells on micropost arrays. Biophys J (2011) 0.94
Substituent effects on edge-to-face aromatic interactions. Chemistry (2002) 0.93
Analysis of behavior and trafficking of dendritic cells within the brain during toxoplasmic encephalitis. PLoS Pathog (2011) 0.93