Trafficking of immune cells in the central nervous system.

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Published in J Clin Invest on May 03, 2010

Authors

Emma H Wilson1, Wolfgang Weninger, Christopher A Hunter

Author Affiliations

1: Division of Biomedical Sciences, University of California, Riverside, California 92521, USA. emmaw@ucr.edu

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Immune response and immunopathology during toxoplasmosis. Semin Immunopathol (2012) 1.38

Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii. PLoS Pathog (2009) 1.37

IL-6 promotes NK cell production of IL-17 during toxoplasmosis. J Immunol (2010) 1.35

Intravital multiphoton imaging of immune responses in the mouse ear skin. Nat Protoc (2012) 1.35

IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. J Immunol (2012) 1.34

Sequence-dependent DNA structure: a database of octamer structural parameters. J Mol Biol (2003) 1.33

Transforming growth factor-beta receptor blockade augments the effectiveness of adoptive T-cell therapy of established solid cancers. Clin Cancer Res (2008) 1.32

Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation. J Immunol (2002) 1.31

The immunobiology of IL-27. Adv Immunol (2012) 1.30

Dendritic cell maturation, but not CD8+ T cell induction, is dependent on type I IFN signaling during vaccination with adenovirus vectors. J Immunol (2005) 1.29

Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection. J Immunol (2010) 1.29

TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development. J Immunol (2005) 1.27

Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737. Clin Cancer Res (2011) 1.27

CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1. J Cell Biol (2006) 1.27

Plasmacytoid dendritic cells are dispensable during primary influenza virus infection. J Immunol (2009) 1.26

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Dendritic cells distinguish individual chemokine signals through CCR7 and CXCR4. J Immunol (2010) 1.25

T cell-intrinsic expression of c-Rel regulates Th1 cell responses essential for resistance to Toxoplasma gondii. J Immunol (2004) 1.23

Synthesis of a molecular trefoil knot by folding and closing on an octahedral coordination template. Nat Chem (2010) 1.22

Development of a system to study CD4+-T-cell responses to transgenic ovalbumin-expressing Toxoplasma gondii during toxoplasmosis. Infect Immun (2004) 1.21

IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis. J Immunol (2009) 1.21

Toxoplasma co-opts host cells it does not invade. PLoS Pathog (2012) 1.21

Chemical double-mutant cycles: dissecting non-covalent interactions. Chem Soc Rev (2006) 1.18

Fibroblast migration is mediated by CD44-dependent TGF beta activation. J Cell Sci (2008) 1.18

Cutting edge: identification of c-Rel-dependent and -independent pathways of IL-12 production during infectious and inflammatory stimuli. J Immunol (2002) 1.18

Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice. Dis Model Mech (2013) 1.18

The immunobiology of interleukin-27. Annu Rev Immunol (2015) 1.18

A role for IL-27 in limiting T regulatory cell populations. J Immunol (2011) 1.17

Cutting Edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter. J Immunol (2004) 1.16

The role of cytokines and their signaling pathways in the regulation of immunity to Toxoplasma gondii. Int Rev Immunol (2002) 1.16

Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection. J Immunol (2004) 1.16

CXCL12 mediates CCR7-independent homing of central memory cells, but not naive T cells, in peripheral lymph nodes. J Exp Med (2004) 1.15

Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice. Blood (2002) 1.14

Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia. J Biol Chem (2002) 1.14

Immune cell migration as a means to control immune privilege: lessons from the CNS and tumors. Immunol Rev (2006) 1.14

Dendritic cells and immunity to leishmaniasis and toxoplasmosis. Curr Opin Immunol (2002) 1.11

Toll-like receptor 4 contributes to poor outcome after intracerebral hemorrhage. Ann Neurol (2011) 1.11

Act1-ivating IL-17 inflammation. Nat Immunol (2007) 1.11

Two distinct activation states of plasmacytoid dendritic cells induced by influenza virus and CpG 1826 oligonucleotide. J Leukoc Biol (2007) 1.11