Published in Genes Chromosomes Cancer on February 01, 2003
Microarray based comparative genomic hybridisation (array-CGH) detects submicroscopic chromosomal deletions and duplications in patients with learning disability/mental retardation and dysmorphic features. J Med Genet (2004) 5.76
A rare-cell detector for cancer. Proc Natl Acad Sci U S A (2004) 3.95
Inheritance of gene density-related higher order chromatin arrangements in normal and tumor cell nuclei. J Cell Biol (2003) 2.12
Genetic alteration and gene expression modulation during cancer progression. Mol Cancer (2004) 1.50
Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients. Cancer Res (2008) 1.32
Negative enrichment by immunomagnetic nanobeads for unbiased characterization of circulating tumor cells from peripheral blood of cancer patients. J Transl Med (2011) 1.15
Circulating tumor cells and DNA as liquid biopsies. Genome Med (2013) 1.06
Genome abnormalities precede prostate cancer and predict clinical relapse. Am J Pathol (2012) 1.03
Reliable single cell array CGH for clinical samples. PLoS One (2014) 0.89
Rapid detection of genomic imbalances using micro-arrays consisting of pooled BACs covering all human chromosome arms. Nucleic Acids Res (2005) 0.84
Genomic Copy Number Variations in the Genomes of Leukocytes Predict Prostate Cancer Clinical Outcomes. PLoS One (2015) 0.78
Approaches to isolation and molecular characterization of disseminated tumor cells. Oncotarget (2015) 0.76
Tumour Heterogeneity: The Key Advantages of Single-Cell Analysis. Int J Mol Sci (2016) 0.75
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell (2006) 27.36
Fine-scale structural variation of the human genome. Nat Genet (2005) 24.31
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell (2006) 16.05
Segmental duplications and copy-number variation in the human genome. Am J Hum Genet (2005) 13.33
Discovery of previously unidentified genomic disorders from the duplication architecture of the human genome. Nat Genet (2006) 10.36
Somatic activation of KIT in distinct subtypes of melanoma. J Clin Oncol (2006) 7.76
Linkage disequilibrium and heritability of copy-number polymorphisms within duplicated regions of the human genome. Am J Hum Genet (2006) 7.70
Cell-free nucleic acids as biomarkers in cancer patients. Nat Rev Cancer (2011) 7.69
A tiling resolution DNA microarray with complete coverage of the human genome. Nat Genet (2004) 7.68
Mutations in GNA11 in uveal melanoma. N Engl J Med (2010) 7.52
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature (2005) 7.24
A pooled analysis of bone marrow micrometastasis in breast cancer. N Engl J Med (2005) 6.86
Array comparative genomic hybridization and its applications in cancer. Nat Genet (2005) 6.69
Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system. Clin Cancer Res (2007) 6.59
Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol (2005) 4.33
Genomic microarrays in human genetic disease and cancer. Hum Mol Genet (2003) 4.15
Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay. Nat Biotechnol (2013) 4.11
Whole genome analysis of genetic alterations in small DNA samples using hyperbranched strand displacement amplification and array-CGH. Genome Res (2003) 4.10
Digital karyotyping. Proc Natl Acad Sci U S A (2002) 3.96
Germline mutations in BAP1 predispose to melanocytic tumors. Nat Genet (2011) 3.91
Circulating tumor cells: liquid biopsy of cancer. Clin Chem (2012) 3.87
The connectome of a decision-making neural network. Science (2012) 3.70
Determinants of BRAF mutations in primary melanomas. J Natl Cancer Inst (2003) 3.65
A survey of tools for variant analysis of next-generation genome sequencing data. Brief Bioinform (2013) 3.60
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer. Immunity (2013) 3.50
Fully automatic quantification of microarray image data. Genome Res (2002) 3.47
Breast tumor copy number aberration phenotypes and genomic instability. BMC Cancer (2006) 3.34
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors. Cancer Cell (2011) 3.23
Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma. Oncogene (2005) 2.99
Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer. Breast Cancer Res (2010) 2.98
MC1R germline variants confer risk for BRAF-mutant melanoma. Science (2006) 2.84
The persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrence. Cancer (2005) 2.74
Review: Biological relevance of disseminated tumor cells in cancer patients. Int J Cancer (2008) 2.72
Tumor metastasis: moving new biological insights into the clinic. Nat Med (2013) 2.71
Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial. Clin Cancer Res (2010) 2.66
Improving melanoma classification by integrating genetic and morphologic features. PLoS Med (2008) 2.52
Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3. Nat Genet (2005) 2.51
Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing. Cancer Res (2013) 2.50
Large-scale variation among human and great ape genomes determined by array comparative genomic hybridization. Genome Res (2003) 2.41
Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors. Cancer Res (2003) 2.34
Comparative genomic hybridization. Annu Rev Genomics Hum Genet (2005) 2.34
Regional copy number-independent deregulation of transcription in cancer. Nat Genet (2006) 2.33
Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells. Clin Cancer Res (2005) 2.31
Circulating tumor cells and circulating tumor DNA. Annu Rev Med (2011) 2.16
HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trial. Breast Cancer Res Treat (2010) 2.12
Inheritance of gene density-related higher order chromatin arrangements in normal and tumor cell nuclei. J Cell Biol (2003) 2.12
Circulating tumor cells in breast cancer: correlation to bone marrow micrometastases, heterogeneous response to systemic therapy and low proliferative activity. Clin Cancer Res (2005) 2.10
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas. Blood (2006) 2.10
Tumor cell dissemination: emerging biological insights from animal models and cancer patients. Cancer Cell (2013) 2.08
Circulating tumor cells and bone marrow micrometastasis. Clin Cancer Res (2008) 2.06
A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation. PLoS One (2006) 2.05
Classifying melanocytic tumors based on DNA copy number changes. Am J Pathol (2003) 2.05
Considerations in the development of circulating tumor cell technology for clinical use. J Transl Med (2012) 2.00
Humanized large-scale expanded endothelial colony-forming cells function in vitro and in vivo. Blood (2009) 2.00
Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway. Cancer Res (2002) 1.96
Targeted inactivation of p53 in human cells does not result in aneuploidy. Cancer Res (2002) 1.86
Chromosomal translocations are associated with poor prognosis in chronic lymphocytic leukemia. Blood (2005) 1.85
Conjunctival melanomas harbor BRAF and NRAS mutations and copy number changes similar to cutaneous and mucosal melanomas. Clin Cancer Res (2013) 1.84
A concept for the standardized detection of disseminated tumor cells in bone marrow from patients with primary breast cancer and its clinical implementation. Cancer (2006) 1.82
Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors. Hum Mol Genet (2004) 1.80
High resolution array-CGH analysis of single cells. Nucleic Acids Res (2006) 1.79
Meta-analysis of the prognostic value of circulating tumor cells in breast cancer. Clin Cancer Res (2012) 1.79
Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation. Chromosoma (2007) 1.78
Cancer micrometastasis and tumour dormancy. APMIS (2008) 1.78
Defining 'chromosomal instability'. Trends Genet (2008) 1.76
ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy. Clin Cancer Res (2011) 1.75
High incidence of EMMPRIN expression in human tumors. Int J Cancer (2006) 1.74
Controversies in clinical cancer dormancy. Proc Natl Acad Sci U S A (2011) 1.71
Mapping segmental and sequence variations among laboratory mice using BAC array CGH. Genome Res (2005) 1.71
Shaping of tumor and drug-resistant genomes by instability and selection. Oncogene (2003) 1.70
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma. Blood (2003) 1.69
A full-coverage, high-resolution human chromosome 22 genomic microarray for clinical and research applications. Hum Mol Genet (2002) 1.69
Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors. Cancer Res (2003) 1.67
Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation. Gastroenterology (2012) 1.63
Circulating miRNAs as surrogate markers for circulating tumor cells and prognostic markers in metastatic breast cancer. Clin Cancer Res (2012) 1.63
Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis. Cancer Cell (2013) 1.62
Tumor-cell homing to lymph nodes and bone marrow and CXCR4 expression in esophageal cancer. J Natl Cancer Inst (2005) 1.60
Circulating tumor cell isolation and diagnostics: toward routine clinical use. Cancer Res (2011) 1.58
High-resolution analysis of paraffin-embedded and formalin-fixed prostate tumors using comparative genomic hybridization to genomic microarrays. Am J Pathol (2003) 1.57