Published in Nucleic Acids Res on February 01, 2003
RNA conformational changes in the life cycles of RNA viruses, viroids, and virus-associated RNAs. Biochim Biophys Acta (2009) 1.07
A genomic map of viroid RNA motifs critical for replication and systemic trafficking. Plant Cell (2008) 1.04
Tertiary structural and functional analyses of a viroid RNA motif by isostericity matrix and mutagenesis reveal its essential role in replication. J Virol (2006) 1.02
Characterization of the RNA motif responsible for the specific interaction of potato spindle tuber viroid RNA (PSTVd) and the tomato protein Virp1. Nucleic Acids Res (2003) 1.02
Processing of nuclear viroids in vivo: an interplay between RNA conformations. PLoS Pathog (2007) 0.98
Evidence for the existence of the loop E motif of Potato spindle tuber viroid in vivo. J Virol (2006) 0.87
The RNA strands of the plus and minus polarities of peach latent mosaic viroid fold into different structures. RNA (2010) 0.86
Chrysanthemum stunt viroid disturbs the photoperiodic response for flowering of chrysanthemum plants. Planta (2004) 0.80
Structural differences within the loop E motif imply alternative mechanisms of viroid processing. RNA (2007) 0.80
Processing of Potato Spindle Tuber Viroid (PSTVd) RNAs in Yeast, a Nonconventional Host. J Virol (2017) 0.75
Architecture of ribosomal RNA: constraints on the sequence of "tetra-loops". Proc Natl Acad Sci U S A (1990) 6.25
How RNA folds. J Mol Biol (1999) 6.14
Nucleotide sequence and secondary structure of potato spindle tuber viroid. Nature (1978) 6.07
A replication cycle for viroids and other small infectious RNA's. Science (1984) 5.18
Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA. Nature (1988) 4.53
Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain. Cell (1997) 4.46
Hierarchy and dynamics of RNA folding. Annu Rev Biophys Biomol Struct (1997) 3.95
A thermodynamic study of unusually stable RNA and DNA hairpins. Nucleic Acids Res (1991) 3.59
Synthesis and purification of large amounts of RNA oligonucleotides. Biotechniques (1991) 3.57
Characterization of RNA hairpin loop stability. Nucleic Acids Res (1988) 3.10
Temperature-gradient gel electrophoresis. Thermodynamic analysis of nucleic acids and proteins in purified form and in cellular extracts. Biophys Chem (1987) 2.91
Thermodynamic parameters for loop formation in RNA and DNA hairpin tetraloops. Nucleic Acids Res (1992) 2.70
Thermal denaturation of double-stranded nucleic acids: prediction of temperatures critical for gradient gel electrophoresis and polymerase chain reaction. Nucleic Acids Res (1994) 2.64
On the wobble GoU and related pairs. RNA (2000) 2.47
Conserved geometrical base-pairing patterns in RNA. Q Rev Biophys (1998) 2.34
Exceptionally stable nucleic acid hairpins. Annu Rev Biophys Biomol Struct (1995) 2.28
Calculating the electrostatic properties of RNA provides new insights into molecular interactions and function. Nat Struct Biol (1999) 2.26
Structure and structure formation of viroids. J Mol Biol (1979) 2.03
Viroids. Annu Rev Biochem (1985) 1.93
Recent insights on RNA folding mechanisms from catalytic RNA. Cell Mol Life Sci (2000) 1.87
Minor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site. Science (1995) 1.86
Ultraviolet light-induced crosslinking reveals a unique region of local tertiary structure in potato spindle tuber viroid and HeLa 5S RNA. Proc Natl Acad Sci U S A (1985) 1.71
RNA synthesis: strategies for the use of bacteriophage RNA polymerases. Gene (1988) 1.64
Base-pair probability profiles of RNA secondary structures. Comput Appl Biosci (1992) 1.62
Non-coding, mRNA-like RNAs database Y2K. Nucleic Acids Res (2000) 1.57
Viroid processing: switch from cleavage to ligation is driven by a change from a tetraloop to a loop E conformation. EMBO J (1997) 1.52
Functional contacts of a transfer RNA synthetase with 2'-hydroxyl groups in the RNA minor groove. Nature (1992) 1.52
Cloned single- and double-stranded DNA copies of potato spindle tuber viroid (PSTV) RNA and co-inoculated subgenomic DNA fragments are infectious. EMBO J (1984) 1.51
Viroid processing: a model involving the central conserved region and hairpin I. Proc Natl Acad Sci U S A (1986) 1.49
Viroid replication is inhibited by alpha-amanitin. Nature (1979) 1.48
RNA structure and the regulation of gene expression. Plant Mol Biol (1996) 1.27
Analysis of RNA structures by temperature-gradient gel electrophoresis: viroid replication and processing. Gene (1988) 1.25
Subcellular localization and rolling circle replication of peach latent mosaic viroid: hallmarks of group A viroids. J Virol (1999) 1.24
A photo-cross-linkable tertiary structure motif found in functionally distinct RNA molecules is essential for catalytic function of the hairpin ribozyme. Biochemistry (1994) 1.17
Description of RNA folding by "simulated annealing". J Mol Biol (1996) 1.17
Potato spindle tuber virus: a plant virus with properties of a free nucleic acid. 3. Subcellular location of PSTV-RNA and the question of whether virions exist in extracts or in situ. Virology (1971) 1.16
Only one of four possible secondary structures of the central conserved region of potato spindle tuber viroid is a substrate for processing in a potato nuclear extract. Nucleic Acids Res (1995) 1.13
Determination of the 28 S ribosomal RNA identity element (G4319) for alpha-sarcin and the relationship of recognition to the selection of the catalytic site. J Mol Biol (1996) 1.07
Insights into specificity of cleavage and mechanism of cell entry from the crystal structure of the highly specific Aspergillus ribotoxin, restrictocin. Structure (1996) 1.06
A single nucleotide substitution converts potato spindle tuber viroid (PSTVd) from a noninfectious to an infectious RNA for nicotiana tabacum. Virology (1996) 1.04
Structural requirements for viroid processing by RNase T1. J Mol Biol (1992) 1.01
Structure of viroid replicative intermediates: physico-chemical studies on SP6 transcripts of cloned oligomeric potato spindle tuber viroid. Nucleic Acids Res (1986) 1.01
Dynamic competition between alternative structures in viroid RNAs simulated by an RNA folding algorithm. J Mol Biol (1998) 1.00
Viroids with hammerhead ribozymes: some unique structural and functional aspects with respect to other members of the group. Biol Chem (1999) 0.99
Analysis of the RNA structural elements involved in the binding of the transcription factor III A from Xenopus laevis. Nucleic Acids Res (1986) 0.90
Infectivity of linear monomeric transcripts of citrus exocortis viroid: terminal sequence requirements for processing. Virology (1994) 0.88
Viroids and the nature of viroid diseases. Arch Virol Suppl (1999) 0.88
Complexes containing both polarity strands of avocado sunblotch viroid: identification in chloroplasts and characterization. Virology (1999) 0.88
Structure and stability of variants of the sarcin-ricin loop of 28S rRNA: NMR studies of the prokaryotic SRL and a functional mutant. RNA (1998) 0.87
Detection and analysis of hairpin II, an essential metastable structural element in viroid replication intermediates. Nucleic Acids Res (2002) 0.86
Oligomeric potato spindle tuber viroid (PSTV) RNA does not process autocatalytically under conditions where other RNAs do. Virology (1987) 0.86
Structural determinants in 5S RNA and TFIIIA for 7S RNP formation. Eur J Biochem (1998) 0.85
Transcripts of the viroid central conserved region contain the local tertiary structural element found in full-length viroid. FEBS Lett (1992) 0.81
The role of the viroid central conserved region in cDNA infectivity. Virology (1990) 0.81
Chemical mapping of co-existing RNA structures. Nucleic Acids Res (1998) 0.80
Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures. Proc Natl Acad Sci U S A (1976) 3.58
Temperature-gradient gel electrophoresis. Thermodynamic analysis of nucleic acids and proteins in purified form and in cellular extracts. Biophys Chem (1987) 2.91
Mismatches in DNA double strands: thermodynamic parameters and their correlation to repair efficiencies. Nucleic Acids Res (1986) 2.73
The conformational transitions in yeast tRNAPhe as studied with tRNAPhe fragments. Eur J Biochem (1973) 2.26
Conformational transitions in viroids and virusoids: comparison of results from energy minimization algorithm and from experimental data. J Biomol Struct Dyn (1984) 2.14
Structure and structure formation of viroids. J Mol Biol (1979) 2.03
Viroids. Annu Rev Biochem (1985) 1.93
Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy. Nat Med (1998) 1.89
Viroids: a class of subviral pathogens. Angew Chem Int Ed Engl (1980) 1.81
A two-dimensional electrophoretic technique for the detection of circular viroids and virusoids. Anal Biochem (1983) 1.63
Subcellular localization of viroids in highly purified nuclei from tomato leaf tissue. EMBO J (1983) 1.59
Viroid processing: switch from cleavage to ligation is driven by a change from a tetraloop to a loop E conformation. EMBO J (1997) 1.52
Multiple pathways of reversion in viroids for conservation of structural elements. EMBO J (1993) 1.44
Imaging of viroids in nuclei from tomato leaf tissue by in situ hybridization and confocal laser scanning microscopy. EMBO J (1989) 1.41
Formation of a thermodynamically metastable structure containing hairpin II is critical for infectivity of potato spindle tuber viroid RNA. EMBO J (1991) 1.38
Equivalent and non-equivalent binding sites for tRNA on aminoacyl-tRNA synthetases. Eur J Biochem (1975) 1.29
Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease. EMBO J (2001) 1.29
RNA structure and the regulation of gene expression. Plant Mol Biol (1996) 1.27
Analysis of RNA structures by temperature-gradient gel electrophoresis: viroid replication and processing. Gene (1988) 1.25
Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis. J Gen Virol (1992) 1.23
Thermodynamic prediction of conserved secondary structure: application to the RRE element of HIV, the tRNA-like element of CMV and the mRNA of prion protein. J Mol Biol (1996) 1.22
Common structural features of different viroids: serial arrangement of double helical sections and internal loops. Nucleic Acids Res (1978) 1.22
Kinetics of conformational changes in tRNA Phe (yeast) as studied by the fluorescence of the Y-base and of formycin substituted for the 3'-terminal adenine. Biophys Chem (1975) 1.16
Fine structure melting of viroids as studied by kinetic methods. Nucleic Acids Res (1979) 1.15
Large-scale purification of viroid RNA using Cs2SO4 gradient centrifugation and high-performance liquid chromatography. Anal Biochem (1983) 1.14
Rapid acquisition of beta-sheet structure in the prion protein prior to multimer formation. Biol Chem (1998) 1.13
Only one of four possible secondary structures of the central conserved region of potato spindle tuber viroid is a substrate for processing in a potato nuclear extract. Nucleic Acids Res (1995) 1.13
Distinct steps in the specific binding of tRNA to aminoacyl-tRNA synthetase. Temperature-jump studies on the serine-specific system from yeast and the tyrosine-specific system from Escherichia coli. Eur J Biochem (1976) 1.11
Helix-coil transitions in double-stranded viral RNA. Fine resolution melting and ionic strength dependence. Biochim Biophys Acta (1980) 1.10
Viroid replication: equilibrium association constant and comparative activity measurements for the viroid-polymerase interaction. Nucleic Acids Res (1984) 1.08
Mechanism of discrimination between cognate and non-cognate tRNAs by phenylalanyl-tRNA synthetase from yeast. Eur J Biochem (1976) 1.06
RNA structural features responsible for potato spindle tuber viroid pathogenicity. Virology (1996) 1.04
Conformation of viroids. Nucleic Acids Res (1977) 1.04
Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form. Biol Chem (2001) 1.04
Molecular model of an alpha-helical prion protein dimer and its monomeric subunits as derived from chemical cross-linking and molecular modeling calculations. J Mol Biol (2007) 1.03
Co-existing structures of an mRNA stability determinant. The 5' region of the Escherichia coli and Serratia marcescens ompA mRNA. J Mol Biol (1993) 1.02
Double-stranded cucumovirus associated RNA 5: experimental analysis of necrogenic and non-necrogenic variants by temperature-gradient gel electrophoresis. Nucleic Acids Res (1987) 1.02
Structure of viroid replicative intermediates: physico-chemical studies on SP6 transcripts of cloned oligomeric potato spindle tuber viroid. Nucleic Acids Res (1986) 1.01
Structural requirements for viroid processing by RNase T1. J Mol Biol (1992) 1.01
The stiffness of dsRNA: hydrodynamic studies on fluorescence-labelled RNA segments of bovine rotavirus. Nucleic Acids Res (1986) 1.01
Complexes of viroids with histones and other proteins. Nucleic Acids Res (1985) 1.01
Nucleic acids in prion preparations: unspecific background or essential component? Philos Trans R Soc Lond B Biol Sci (1994) 1.01
Double-stranded cucumovirus associated RNA 5: which sequence variations may be detected by optical melting and temperature-gradient gel electrophoresis? Nucleic Acids Res (1987) 1.00
Prion rods contain small amounts of two host sphingolipids as revealed by thin-layer chromatography and mass spectrometry. Biol Chem (1998) 1.00
Search for a putative scrapie genome in purified prion fractions reveals a paucity of nucleic acids. J Gen Virol (1991) 0.99
The coupling of conformational transitions in alanine specific transfer ribonucleic acid from yeast studied by a modified differential absorption technique. Eur J Biochem (1970) 0.98
Inhibition of cytotoxicity and amyloid fibril formation by a D-amino acid peptide that specifically binds to Alzheimer's disease amyloid peptide. Protein Eng Des Sel (2008) 0.96
Mechanism of tRNA-synthetase recognition: role of terminal A. Nucleic Acids Res (1977) 0.96
Prion rods contain an inert polysaccharide scaffold. Biol Chem (1999) 0.95
Fly larvae and pupae as vectors for scrapie. Lancet (1999) 0.94
Cooperative helix-coil transitions in half molecules of phenylalanine specific tRNA from yeast. FEBS Lett (1969) 0.93
Dimerization and bonding of a zinc porphyrin cation radical. Thermodynamics and fast reaction kinetics. J Am Chem Soc (1972) 0.93
Kinetic study of the three conformational transitions of alanine specific transfer RNA from yeast. Eur J Biochem (1970) 0.91
Neurotoxicity but not infectivity of prion proteins can be induced reversibly in vitro. Arch Virol Suppl (2000) 0.91
Structural transitions in viroid-like RNAs associated with cadang-cadang disease, velvet tobacco mottle virus, and Solanum nodiflorum mottle virus. Nucleic Acids Res (1982) 0.90
Calorimetric studies on viroids. Nucleic Acids Res (1978) 0.90
Interdependence of pathogenicity and replicability with potato spindle tuber viroid. Virology (1995) 0.89
Correlation between bending of the VM region and pathogenicity of different Potato Spindle Tuber Viroid strains. RNA (1998) 0.89
Analysis of nucleic acids in purified scrapie prion preparations. Arch Virol Suppl (1993) 0.88
Thermal unfolding of yeast glycine transfer RNA. Biochemistry (1976) 0.88
Thermodynamics and kinetics of the interaction of phenylalanine-specific tRNA from yeast with its cognate synthetase as studied by the flourescence of the Y-base. FEBS Lett (1973) 0.87
Enzymatic methylations: III. Cadaverine-induced conformational changes of E. coli tRNA fMet as evidenced by the availability of a specific adenosine and a specific cytidine residue for methylation. Nucleic Acids Res (1974) 0.85
Evidence from ultraviolet absorbance measurements for a codon-induced conformational change in lysine tRNA from Escherichia coli. Proc Natl Acad Sci U S A (1979) 0.85
Viroids. Subcellular location and structure of replicative intermediates. Ann N Y Acad Sci (1987) 0.85
Kinetic studies on the interaction of seryl-tRNA synthetase with tRNA(Ser) and ser-tRNA(ser) from yeast. FEBS Lett (1973) 0.84
Resolution of five conformational transitions in phenylalaninespecific tRNA from yeast. FEBS Lett (1970) 0.84
Steps of mRNA translocation in protein biosynthesis. Nature (1981) 0.84
Rabbit liver tRNA1Val:II. unusual secondary structure of T psi C stem and loop due to a U54:A60 base pair. Nucleic Acids Res (1977) 0.83
Temperature gradient gel electrophoresis (TGGE) for the detection of polymorphic DNA and RNA. Methods Mol Biol (1994) 0.83
Cyclosporin synthetase is a 1.4 MDa multienzyme polypeptide. Re-evaluation of the molecular mass of various peptide synthetases. FEBS Lett (1992) 0.83
Stiffness of viroids and viroid-like RNA in solution. Nucleic Acids Res (1982) 0.83
Transcription of potato spindle tuber viroid by RNA polymerase II starts predominantly at two specific sites. Nucleic Acids Res (2001) 0.82
The structural transition of the prion protein into its pathogenic conformation is induced by unmasking hydrophobic sites. J Mol Biol (2004) 0.82
Biolistic inoculation of plants with viroid nucleic acids. J Virol Methods (2004) 0.81
Heat stability of prion rods and recombinant prion protein in water, lipid and lipid-water mixtures. J Gen Virol (2001) 0.81
Chemical mapping of co-existing RNA structures. Nucleic Acids Res (1998) 0.80
Melting curves on less than 1 microgram of nucleic acid. Anal Biochem (1980) 0.80
Mechanism of tRNA-aminoacyl-tRNA synthetase recognition: influence of aminoalkyladenylates. Biochemistry (1978) 0.80
A microcell for the temperature-jump technique. Anal Biochem (1982) 0.80
Experimental transmission of pospiviroid populations to weed species characteristic of potato and hop fields. J Virol (2007) 0.80
High resolution SSCP by optimization of the temperature by transverse TGGE. Nucleic Acids Res (1995) 0.80
Binding of tRNA in different functional states to Escherichia coli ribosomes as measured by velocity sedimentation. Eur J Biochem (1982) 0.80
Thermodynamic properties of the three conformational transitions of alanine specific transfer RNA from yeast. Biochem Biophys Res Commun (1969) 0.80
Mechanism of the interaction between ribosomal protein S1 and oligonucleotides. Nucleic Acids Res (1981) 0.79
Inhibition of viroid infection by antisense RNA expression in transgenic plants. Biol Chem Hoppe Seyler (1994) 0.79
Thermostable variants of subtilisin selected by temperature-gradient gel electrophoresis. Electrophoresis (1996) 0.78
Analysis of the conformational transitions of proteins by temperature-gradient gel electrophoresis. Electrophoresis (1990) 0.78
Isolation and characterization of high-molecular mass DNA from hair shafts. Biol Chem Hoppe Seyler (1988) 0.78
Enzymatic biosynthesis of cyclosporin A and analogues. Biochimie (1992) 0.78
Analysis of prion protein aggregates in blood and brain from pre-clinical and clinical BSE cases. Vet Microbiol (2013) 0.77
High-performance liquid chromatography of DNA restriction fragments. J Chromatogr (1985) 0.77
The variability of hop latent viroid as induced upon heat treatment. Virology (2001) 0.77
A stopped-flow apparatus with light-scattering detection and its application to biochemical reactions. Proc Natl Acad Sci U S A (1973) 0.75
Random mutagenesis of the weak calcium binding site in subtilisin Carlsberg and screening for thermostability by temperature-gradient gel electrophoresis. Adv Exp Med Biol (1996) 0.75
TGGE in quantitative PCR of DNA and RNA. Methods Mol Biol (1994) 0.75
Influence of lipid membranes on the conformational transitions of nucleic acids. J Biomol Struct Dyn (1986) 0.75