Published in Mol Endocrinol on February 06, 2003
The hypothalamic neuropeptide oxytocin is required for formation of the neurovascular interface of the pituitary. Dev Cell (2011) 1.46
Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting. Mol Cell Biol (2005) 1.30
Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor. Proc Natl Acad Sci U S A (2011) 1.05
Optogenetic elevation of endogenous glucocorticoid level in larval zebrafish. Front Neural Circuits (2013) 1.03
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Zebrafish usp39 mutation leads to rb1 mRNA splicing defect and pituitary lineage expansion. PLoS Genet (2011) 0.92
Graded hedgehog and fibroblast growth factor signaling independently regulate pituitary cell fates and help establish the pars distalis and pars intermedia of the zebrafish adenohypophysis. Endocrinology (2008) 0.88
The transcriptomics of glucocorticoid receptor signaling in developing zebrafish. PLoS One (2013) 0.87
Glucocorticoid receptor, but not mineralocorticoid receptor, mediates cortisol regulation of epidermal ionocyte development and ion transport in zebrafish (danio rerio). PLoS One (2013) 0.86
Enhancer turnover and conserved regulatory function in vertebrate evolution. Philos Trans R Soc Lond B Biol Sci (2013) 0.85
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In vivo time-lapse imaging delineates the zebrafish pituitary proopiomelanocortin lineage boundary regulated by FGF3 signal. Dev Biol (2008) 0.80
A laser pointer driven microheater for precise local heating and conditional gene regulation in vivo. Microheater driven gene regulation in zebrafish. BMC Dev Biol (2009) 0.80
Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis. Development (2013) 0.79
Developing a sense of scents: plasticity in olfactory placode formation. Brain Res Bull (2007) 0.78
Optogenetically enhanced pituitary corticotroph cell activity post-stress onset causes rapid organizing effects on behaviour. Nat Commun (2016) 0.77
Rx3 and Shh direct anisotropic growth and specification in the zebrafish tuberal/anterior hypothalamus. Development (2016) 0.75
Changing the Scale and Efficiency of Chemical Warfare Countermeasure Discovery Using the Zebrafish. Drug Discov Today Dis Models (2013) 0.75
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The Basal NPO crh Fluctuation is Sustained Under Compromised Glucocorticoid Signaling in Diurnal Zebrafish. Front Neurosci (2015) 0.75
Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish. Sci Rep (2017) 0.75
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol (2004) 12.12
Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol (2011) 8.34
Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol (2003) 5.73
Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metab (2008) 4.91
Myc-induced T cell leukemia in transgenic zebrafish. Science (2003) 3.15
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. Genes Dev (2004) 2.99
Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1). J Clin Endocrinol Metab (2012) 2.87
In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Nat Methods (2011) 2.85
Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic Acids Res (2013) 2.73
Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family. Blood (2008) 2.68
TALEN-mediated precise genome modification by homologous recombination in zebrafish. Nat Methods (2013) 2.64
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell (2008) 2.46
CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood (2012) 2.43
Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol (2006) 2.35
TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell (2010) 2.33
Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay. Arterioscler Thromb Vasc Biol (2003) 2.26
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell Stem Cell (2008) 2.17
The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Biol (2007) 2.10
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev (2002) 2.02
FoxH1 negatively modulates flk1 gene expression and vascular formation in zebrafish. Dev Biol (2007) 2.02
Acromegaly: an endocrine society clinical practice guideline. J Clin Endocrinol Metab (2014) 2.01
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes. J Neurochem (2006) 2.00
Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proc Natl Acad Sci U S A (2007) 1.96
Cloned zebrafish by nuclear transfer from long-term-cultured cells. Nat Biotechnol (2002) 1.89
Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding. Dev Cell (2008) 1.82
Pituitary tumor-transforming gene: physiology and implications for tumorigenesis. Endocr Rev (2007) 1.79
N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites. Development (2003) 1.79
Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. ACS Nano (2011) 1.75
Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials. ACS Nano (2011) 1.68
Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm. Dev Cell (2002) 1.68
Bmp and Fgf signaling are essential for liver specification in zebrafish. Development (2007) 1.66
PLS3 mutations in X-linked osteoporosis with fractures. N Engl J Med (2013) 1.66
A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. Dev Biol (2007) 1.65
Characterization of embryonic globin genes of the zebrafish. Dev Biol (2003) 1.65
The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS Biol (2004) 1.64
Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants. Blood (2005) 1.64
Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome. PLoS One (2006) 1.60
Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Dev Biol (2007) 1.58
Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulation. Development (2006) 1.57
The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. Development (2008) 1.54
parachute/n-cadherin is required for morphogenesis and maintained integrity of the zebrafish neural tube. Development (2002) 1.53
Interplay among Etsrp/ER71, Scl, and Alk8 signaling controls endothelial and myeloid cell formation. Blood (2008) 1.51
Angiogenesis in endocrine tumors. Endocr Rev (2003) 1.50
EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas. J Clin Invest (2011) 1.49
A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Res (2013) 1.48
Wnt5 signaling in vertebrate pancreas development. BMC Biol (2005) 1.45
Asymmetric expression of the BMP antagonists chordin and gremlin in the sea anemone Nematostella vectensis: implications for the evolution of axial patterning. Dev Biol (2006) 1.44
Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish. Am J Hum Genet (2012) 1.43
Interrelation of immunity and tissue repair or regeneration. Semin Cell Dev Biol (2009) 1.42
Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis. Mol Endocrinol (2005) 1.40
REREa/Atrophin-2 interacts with histone deacetylase and Fgf8 signaling to regulate multiple processes of zebrafish development. Dev Dyn (2007) 1.38
Control of Dpp morphogen signalling by a secreted feedback regulator. Nat Cell Biol (2010) 1.38
Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42. Am J Hum Genet (2011) 1.37
Zebrafish in endocrine systems: recent advances and implications for human disease. Annu Rev Physiol (2011) 1.36
Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients. J Clin Endocrinol Metab (2011) 1.34
Surface defects on plate-shaped silver nanoparticles contribute to its hazard potential in a fish gill cell line and zebrafish embryos. ACS Nano (2012) 1.32
Inactivation of serine protease Matriptase1a by its inhibitor Hai1 is required for epithelial integrity of the zebrafish epidermis. Development (2007) 1.32
Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy. Cell Metab (2013) 1.32
p21(Cip1) restrains pituitary tumor growth. Proc Natl Acad Sci U S A (2008) 1.31
SMIF, a Smad4-interacting protein that functions as a co-activator in TGFbeta signalling. Nat Cell Biol (2002) 1.31
Overexpressed pituitary tumor-transforming gene causes aneuploidy in live human cells. Endocrinology (2003) 1.29
The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development. PLoS Genet (2009) 1.29
Analyses of pancreas development by generation of gfp transgenic zebrafish using an exocrine pancreas-specific elastaseA gene promoter. Exp Cell Res (2006) 1.28
Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death. J Neurosci (2007) 1.27
Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish. Dev Biol (2007) 1.26
Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells. Nat Neurosci (2007) 1.25
Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes. PLoS Genet (2010) 1.25
Functional role of estrogen in pituitary tumor pathogenesis. J Clin Invest (2002) 1.24
Acromegaly. Endocrinol Metab Clin North Am (2008) 1.23
Adenohypophysis formation in the zebrafish and its dependence on sonic hedgehog. Dev Biol (2003) 1.21
Differentiation of the vertebrate retina is coordinated by an FGF signaling center. Dev Cell (2005) 1.20
Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Dev Cell (2008) 1.20
A critical analysis of clinically available somatostatin analog formulations for therapy of acromegaly. J Clin Endocrinol Metab (2008) 1.19
Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation. Development (2004) 1.19
Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes. Proc Natl Acad Sci U S A (2003) 1.19
Overexpression of mini-agrin in skeletal muscle increases muscle integrity and regenerative capacity in laminin-alpha2-deficient mice. FASEB J (2005) 1.18
PPAR-gamma receptor ligands: novel therapy for pituitary adenomas. J Clin Invest (2003) 1.18
Early multipotential pituitary focal hyperplasia in the alpha-subunit of glycoprotein hormone-driven pituitary tumor-transforming gene transgenic mice. Mol Endocrinol (2005) 1.18
Diversin regulates heart formation and gastrulation movements in development. Proc Natl Acad Sci U S A (2006) 1.16
Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (2006) 1.16
Body mass index determines evoked growth hormone (GH) responsiveness in normal healthy male subjects: diagnostic caveat for adult GH deficiency. J Clin Endocrinol Metab (2004) 1.15
Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages. J Cell Biol (2007) 1.15
Molecular targets in pituitary tumours. Nat Rev Cancer (2004) 1.14
The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Hum Mol Genet (2006) 1.14
Functional PPAR-gamma receptor is a novel therapeutic target for ACTH-secreting pituitary adenomas. Nat Med (2002) 1.14
Fgf3 signaling from the ventral diencephalon is required for early specification and subsequent survival of the zebrafish adenohypophysis. Development (2004) 1.13
Craniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized degradation of retinoic acid. Am J Hum Genet (2011) 1.12
Temtamy preaxial brachydactyly syndrome is caused by loss-of-function mutations in chondroitin synthase 1, a potential target of BMP signaling. Am J Hum Genet (2010) 1.11
Restriction of retinoic acid activity by Cyp26b1 is required for proper timing and patterning of osteogenesis during zebrafish development. Development (2008) 1.11
Foxi3 transcription factors and Notch signaling control the formation of skin ionocytes from epidermal precursors of the zebrafish embryo. Dev Biol (2007) 1.11
Ribosomal protein L11 mutation in zebrafish leads to haematopoietic and metabolic defects. Br J Haematol (2010) 1.10
Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues. Dev Biol (2002) 1.10
Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth. Cancer Res (2007) 1.09
Reverse genetic approaches in zebrafish. J Genet Genomics (2012) 1.09
The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model. EMBO Rep (2006) 1.09