Published in Nat Neurosci on May 07, 2007
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p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain. Nat Neurosci (2010) 1.22
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High expression and purification of amino-terminal fragment of human amyloid precursor protein in Pichia pastoris and partial analysis of its properties. Biomed Res Int (2013) 0.75
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Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol (2011) 8.34
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Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol (2003) 5.73
Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metab (2008) 4.91
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J Neurochem (2003) 3.79
Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs. Cell (2010) 3.57
Glial cells generate neurons: the role of the transcription factor Pax6. Nat Neurosci (2002) 3.37
Myc-induced T cell leukemia in transgenic zebrafish. Science (2003) 3.15
Differentiation of mouse embryonic stem cells into a defined neuronal lineage. Nat Neurosci (2004) 3.11
Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic Acids Res (2013) 2.73
Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. Nat Biotechnol (2009) 2.70
Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family. Blood (2008) 2.68
TALEN-mediated precise genome modification by homologous recombination in zebrafish. Nat Methods (2013) 2.64
The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system. Nat Neurosci (2002) 2.53
Generation of a defined and uniform population of CNS progenitors and neurons from mouse embryonic stem cells. Nat Protoc (2007) 2.48
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell (2008) 2.46
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat Neurosci (2008) 2.38
Diagnostic efficacy of gadoxetic acid (Primovist)-enhanced MRI and spiral CT for a therapeutic strategy: comparison with intraoperative and histopathologic findings in focal liver lesions. Eur Radiol (2007) 2.37
Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol (2006) 2.35
TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell (2010) 2.33
Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay. Arterioscler Thromb Vasc Biol (2003) 2.26
Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy. Proc Natl Acad Sci U S A (2006) 2.26
Presynaptic induction of heterosynaptic associative plasticity in the mammalian brain. Nature (2003) 2.13
Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proc Natl Acad Sci U S A (2007) 1.96
Guidelines for reporting the use of mass spectrometry in proteomics. Nat Biotechnol (2008) 1.90
Cloned zebrafish by nuclear transfer from long-term-cultured cells. Nat Biotechnol (2002) 1.89
Radial glial cells defined and major intermediates between embryonic stem cells and CNS neurons. Neuron (2005) 1.87
The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons. J Neurosci (2005) 1.86
Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth. J Neurosci (2010) 1.85
Prospective assessment of hepatic function and mechanisms of dysfunction in the critically ill. Shock (2009) 1.82
Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. ACS Nano (2011) 1.75
Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma. Am J Hum Genet (2009) 1.71
Tau EGFP embryonic stem cells: an efficient tool for neuronal lineage selection and transplantation. J Neurosci Res (2002) 1.71
Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials. ACS Nano (2011) 1.68
BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons. J Cell Biol (2012) 1.65
Characterization of embryonic globin genes of the zebrafish. Dev Biol (2003) 1.65
The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS Biol (2004) 1.64
Single-step detection of mutant huntingtin in animal and human tissues: a bioassay for Huntington's disease. Anal Biochem (2009) 1.64
Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a rho-dependent mechanism. J Neurosci (2002) 1.64
Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants. Blood (2005) 1.64
Progenitor cells of the testosterone-producing Leydig cells revealed. J Cell Biol (2004) 1.60
Endogenous galectin-1 enforces class I-restricted TCR functional fate decisions in thymocytes. Blood (2008) 1.60
Two-year follow-up of subthalamic deep brain stimulation in Parkinson's disease. Mov Disord (2003) 1.58
Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not. Nature (2010) 1.56
Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease. J Neurochem (2007) 1.54
Interplay among Etsrp/ER71, Scl, and Alk8 signaling controls endothelial and myeloid cell formation. Blood (2008) 1.51
Tumor cells secrete galectin-1 to enhance endothelial cell activity. Cancer Res (2010) 1.50
A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Res (2013) 1.48
Phylogenetic analysis of the vertebrate galectin family. Mol Biol Evol (2004) 1.46
Wnt5 signaling in vertebrate pancreas development. BMC Biol (2005) 1.45
Dendritic spine heterogeneity determines afferent-specific Hebbian plasticity in the amygdala. Neuron (2005) 1.43
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome. Proc Natl Acad Sci U S A (2012) 1.40
Galectin-3 mediates aldosterone-induced vascular fibrosis. Arterioscler Thromb Vasc Biol (2012) 1.37
Surface defects on plate-shaped silver nanoparticles contribute to its hazard potential in a fish gill cell line and zebrafish embryos. ACS Nano (2012) 1.32
Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy. Cell Metab (2013) 1.32
A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells. Proc Natl Acad Sci U S A (2006) 1.30
Analyses of pancreas development by generation of gfp transgenic zebrafish using an exocrine pancreas-specific elastaseA gene promoter. Exp Cell Res (2006) 1.28
Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death. J Neurosci (2007) 1.27
Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish. Dev Biol (2007) 1.26
Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons. J Neurosci (2002) 1.24
Galectins in the tumor endothelium: opportunities for combined cancer therapy. Blood (2007) 1.24
The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus. Proc Natl Acad Sci U S A (2005) 1.24
Most effective stimulation site in subthalamic deep brain stimulation for Parkinson's disease. Mov Disord (2004) 1.22
Galectin-3 contributes to neonatal hypoxic-ischemic brain injury. Neurobiol Dis (2010) 1.21
Manic episode with psychotic symptoms induced by subthalamic nucleus stimulation in a patient with Parkinson's disease. Mov Disord (2003) 1.20
Overexpression of mini-agrin in skeletal muscle increases muscle integrity and regenerative capacity in laminin-alpha2-deficient mice. FASEB J (2005) 1.18
Shuttling of galectin-3 between the nucleus and cytoplasm. Glycobiology (2002) 1.16
Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (2006) 1.16
Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages. J Cell Biol (2007) 1.15
Galectin-7 in the control of epidermal homeostasis after injury. Mol Biol Cell (2008) 1.11
Ribosomal protein L11 mutation in zebrafish leads to haematopoietic and metabolic defects. Br J Haematol (2010) 1.10
Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues. Dev Biol (2002) 1.10
Role of galectin-3 in leukocyte recruitment in a murine model of lung infection by Streptococcus pneumoniae. J Immunol (2008) 1.10
Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons. Stem Cells (2012) 1.09
Reverse genetic approaches in zebrafish. J Genet Genomics (2012) 1.09
The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model. EMBO Rep (2006) 1.09
Pituitary corticotroph ontogeny and regulation in transgenic zebrafish. Mol Endocrinol (2003) 1.09
p53 family in development. Mech Dev (2008) 1.08
Survival and Axonal Elongation of Adult Rat Retinal Ganglion Cells. Eur J Neurosci (1989) 1.08
High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles. ACS Nano (2011) 1.08
Optogenetic control of transcription in zebrafish. PLoS One (2012) 1.07
Scl isoforms act downstream of etsrp to specify angioblasts and definitive hematopoietic stem cells. Blood (2010) 1.06
Pathway analysis tools and toxicogenomics reference databases for risk assessment. Pharmacogenomics (2008) 1.06
NXT2 is required for embryonic heart development in zebrafish. BMC Dev Biol (2005) 1.06
Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor. Proc Natl Acad Sci U S A (2011) 1.05
Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6. Cell Stem Cell (2007) 1.05
The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans. Proc Natl Acad Sci U S A (2004) 1.05
Galectin-1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 function. Eur J Immunol (2008) 1.05
Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes. Dev Dyn (2005) 1.04
Genetic analysis of early endocrine pancreas formation in zebrafish. Mol Endocrinol (2005) 1.04
New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures. Drug Metab Rev (2003) 1.04
Src-family kinases stabilize the neuromuscular synapse in vivo via protein interactions, phosphorylation, and cytoskeletal linkage of acetylcholine receptors. J Neurosci (2005) 1.03
Muscle-selective synaptic disassembly and reorganization in MuSK antibody positive MG mice. Exp Neurol (2011) 1.03
A novel xenograft model in zebrafish for high-resolution investigating dynamics of neovascularization in tumors. PLoS One (2011) 1.03
The zebrafish as a model for human disease. Front Biosci (2002) 1.02
Isoelectric focusing and two-dimensional gel electrophoresis. Methods Enzymol (2009) 1.02
Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state. Proc Natl Acad Sci U S A (2012) 1.02
Galectin-3 maintains cell motility from the subventricular zone to the olfactory bulb. J Cell Sci (2011) 1.01