Published in J Biol Chem on February 10, 2003
Retracted Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 1.71
How a DNA polymerase clamp loader opens a sliding clamp. Science (2011) 1.56
The AAA+ superfamily of functionally diverse proteins. Genome Biol (2008) 1.44
High degree of coordination and division of labor among subunits in a homomeric ring ATPase. Cell (2012) 1.35
Multiple ATP-hydrolyzing sites that potentially function in cytoplasmic dynein. Proc Natl Acad Sci U S A (2004) 1.32
Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex. Proc Natl Acad Sci U S A (2004) 1.20
Loading clamps for DNA replication and repair. DNA Repair (Amst) (2009) 1.12
Replication clamps and clamp loaders. Cold Spring Harb Perspect Biol (2013) 1.10
Distinct roles for ATP binding and hydrolysis at individual subunits of an archaeal clamp loader. EMBO J (2004) 1.07
Temporal correlation of DNA binding, ATP hydrolysis, and clamp release in the clamp loading reaction catalyzed by the Escherichia coli gamma complex. Biochemistry (2009) 1.07
Direct evidence that a conserved arginine in RuvB AAA+ ATPase acts as an allosteric effector for the ATPase activity of the adjacent subunit in a hexamer. Proc Natl Acad Sci U S A (2004) 1.06
Communication between subunits within an archaeal clamp-loader complex. EMBO J (2006) 1.03
Multiple ATP binding is required to stabilize the "activated" (clamp open) clamp loader of the T4 DNA replication complex. J Biol Chem (2008) 1.01
Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97. Proc Natl Acad Sci U S A (2012) 0.99
Hda monomerization by ADP binding promotes replicase clamp-mediated DnaA-ATP hydrolysis. J Biol Chem (2008) 0.97
The Escherichia coli clamp loader can actively pry open the β-sliding clamp. J Biol Chem (2011) 0.96
Comparison of the multiple oligomeric structures observed for the Rvb1 and Rvb2 proteins. Biochem Cell Biol (2010) 0.95
Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission. Proc Natl Acad Sci U S A (2012) 0.93
Clamp loader ATPases and the evolution of DNA replication machinery. BMC Biol (2012) 0.92
Torsins: not your typical AAA+ ATPases. Crit Rev Biochem Mol Biol (2015) 0.91
Bacterial replicases and related polymerases. Curr Opin Chem Biol (2011) 0.90
Evolutionary clues to eukaryotic DNA clamp-loading mechanisms: analysis of the functional constraints imposed on replication factor C AAA+ ATPases. Nucleic Acids Res (2005) 0.89
RecA acts as a switch to regulate polymerase occupancy in a moving replication fork. Proc Natl Acad Sci U S A (2013) 0.88
A central swivel point in the RFC clamp loader controls PCNA opening and loading on DNA. J Mol Biol (2011) 0.87
The RFC clamp loader: structure and function. Subcell Biochem (2012) 0.86
The β sliding clamp closes around DNA prior to release by the Escherichia coli clamp loader γ complex. J Biol Chem (2012) 0.85
Dual functions, clamp opening and primer-template recognition, define a key clamp loader subunit. J Mol Biol (2004) 0.84
Conserved residues in the delta subunit help the E. coli clamp loader, gamma complex, target primer-template DNA for clamp assembly. Nucleic Acids Res (2008) 0.84
Only one ATP-binding DnaX subunit is required for initiation complex formation by the Escherichia coli DNA polymerase III holoenzyme. J Biol Chem (2010) 0.84
Hypothesis: bacterial clamp loader ATPase activation through DNA-dependent repositioning of the catalytic base and of a trans-acting catalytic threonine. Nucleic Acids Res (2006) 0.76
The opened processivity clamp slides into view. Proc Natl Acad Sci U S A (2005) 0.75
The interplay of primer-template DNA phosphorylation status and single-stranded DNA binding proteins in directing clamp loaders to the appropriate polarity of DNA. Nucleic Acids Res (2014) 0.75
Cellular DNA replicases: components and dynamics at the replication fork. Annu Rev Biochem (2005) 5.50
Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex. Nature (2004) 4.37
Structure of a sliding clamp on DNA. Cell (2008) 2.42
A sliding-clamp toolbelt binds high- and low-fidelity DNA polymerases simultaneously. Mol Cell (2005) 2.23
Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex. J Biol Chem (2003) 2.15
Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease. J Biol Chem (2007) 2.09
The replisome uses mRNA as a primer after colliding with RNA polymerase. Nature (2008) 2.08
Characterization of a triple DNA polymerase replisome. Mol Cell (2007) 2.04
Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture. J Biol Chem (2002) 2.01
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III. Cell (2006) 1.94
The replication clamp-loading machine at work in the three domains of life. Nat Rev Mol Cell Biol (2006) 1.92
Clamp loaders and sliding clamps. Curr Opin Struct Biol (2002) 1.77
Direct restart of a replication fork stalled by a head-on RNA polymerase. Science (2010) 1.77
Fidelity of Escherichia coli DNA polymerase IV. Preferential generation of small deletion mutations by dNTP-stabilized misalignment. J Biol Chem (2002) 1.77
Motors and switches: AAA+ machines within the replisome. Nat Rev Mol Cell Biol (2002) 1.74
The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. Cell (2009) 1.72
DnaB drives DNA branch migration and dislodges proteins while encircling two DNA strands. Mol Cell (2002) 1.70
Functional uncoupling of twin polymerases: mechanism of polymerase dissociation from a lagging-strand block. J Biol Chem (2004) 1.66
Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase. Proc Natl Acad Sci U S A (2009) 1.64
Replicative helicase loaders: ring breakers and ring makers. Curr Biol (2003) 1.64
How a DNA polymerase clamp loader opens a sliding clamp. Science (2011) 1.56
Replisome mechanics: insights into a twin DNA polymerase machine. Trends Microbiol (2007) 1.49
The DnaC helicase loader is a dual ATP/ADP switch protein. EMBO J (2002) 1.42
Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair. EMBO J (2003) 1.42
The beta sliding clamp binds to multiple sites within MutL and MutS. J Biol Chem (2006) 1.37
Mechanism of the E. coli tau processivity switch during lagging-strand synthesis. Mol Cell (2003) 1.33
Mechanism of proliferating cell nuclear antigen clamp opening by replication factor C. J Biol Chem (2006) 1.32
Twin DNA pumps of a hexameric helicase provide power to simultaneously melt two duplexes. Mol Cell (2004) 1.32
A peptide switch regulates DNA polymerase processivity. Proc Natl Acad Sci U S A (2003) 1.29
Whither the replisome: emerging perspectives on the dynamic nature of the DNA replication machinery. Cell Cycle (2009) 1.28
DNA polymerase clamp loaders and DNA recognition. FEBS Lett (2005) 1.28
Analysis of the role of PCNA-DNA contacts during clamp loading. BMC Struct Biol (2010) 1.25
Replisome fate upon encountering a leading strand block and clearance from DNA by recombination proteins. J Biol Chem (2007) 1.23
The replication factor C clamp loader requires arginine finger sensors to drive DNA binding and proliferating cell nuclear antigen loading. J Biol Chem (2006) 1.22
DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA. J Biol Chem (2008) 1.22
Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex. Proc Natl Acad Sci U S A (2004) 1.20
DNA replication: keep moving and don't mind the gap. Mol Cell (2006) 1.20
Replication factor C clamp loader subunit arrangement within the circular pentamer and its attachment points to proliferating cell nuclear antigen. J Biol Chem (2003) 1.19
Efficiency and accuracy of SOS-induced DNA polymerases replicating benzo[a]pyrene-7,8-diol 9,10-epoxide A and G adducts. J Biol Chem (2001) 1.17
Motion of a DNA sliding clamp observed by single molecule fluorescence spectroscopy. J Biol Chem (2008) 1.14
What happens when replication and transcription complexes collide? Cell Cycle (2010) 1.14
Crystal structure of the chi:psi sub-assembly of the Escherichia coli DNA polymerase clamp-loader complex. Eur J Biochem (2004) 1.12
Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp. J Biol Chem (2003) 1.12
Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: II. Uncoupling the beta and DNA binding activities of the gamma complex. J Biol Chem (2003) 1.10
Temporal correlation of DNA binding, ATP hydrolysis, and clamp release in the clamp loading reaction catalyzed by the Escherichia coli gamma complex. Biochemistry (2009) 1.07
Mechanism of polymerase collision release from sliding clamps on the lagging strand. EMBO J (2009) 1.05
Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: I. Two distinct activities for individual ATP sites in the gamma complex. J Biol Chem (2003) 1.05
Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Proc Natl Acad Sci U S A (2008) 1.04
Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium. BMC Struct Biol (2006) 1.03
Increased dNTP binding affinity reveals a nonprocessive role for Escherichia coli beta clamp with DNA polymerase IV. J Biol Chem (2004) 1.03
Cytoplasmic domain requirements for Frazzled-mediated attractive axon turning at the Drosophila midline. Development (2007) 1.01
Replisome structure and conformational dynamics underlie fork progression past obstacles. Curr Opin Cell Biol (2009) 0.99
Mapping the interaction of DNA with the Escherichia coli DNA polymerase clamp loader complex. Nat Struct Mol Biol (2005) 0.98
New insights into replisome fluidity during chromosome replication. Trends Biochem Sci (2012) 0.98
SnapShot: The replisome. Cell (2010) 0.96
A slow ATP-induced conformational change limits the rate of DNA binding but not the rate of beta clamp binding by the escherichia coli gamma complex clamp loader. J Biol Chem (2009) 0.96
The Escherichia coli clamp loader can actively pry open the β-sliding clamp. J Biol Chem (2011) 0.96
Conserved interactions in the Staphylococcus aureus DNA PolC chromosome replication machine. J Biol Chem (2005) 0.95
Replisome dynamics and use of DNA trombone loops to bypass replication blocks. Mol Biosyst (2008) 0.95
Clamp loader ATPases and the evolution of DNA replication machinery. BMC Biol (2012) 0.92
Involvement of the beta clamp in methyl-directed mismatch repair in vitro. J Biol Chem (2009) 0.91
Single-molecule analysis of the Escherichia coli replisome and use of clamps to bypass replication barriers. FEBS Lett (2010) 0.91
A structural role for the PHP domain in E. coli DNA polymerase III. BMC Struct Biol (2013) 0.90
Replication factor C is a more effective proliferating cell nuclear antigen (PCNA) opener than the checkpoint clamp loader, Rad24-RFC. J Biol Chem (2011) 0.89
The essential C family DnaE polymerase is error-prone and efficient at lesion bypass. J Biol Chem (2003) 0.89
Fluorescence measurements on the E.coli DNA polymerase clamp loader: implications for conformational changes during ATP and clamp binding. J Mol Biol (2004) 0.88
Analysis of a multicomponent thermostable DNA polymerase III replicase from an extreme thermophile. J Biol Chem (2002) 0.87
A central swivel point in the RFC clamp loader controls PCNA opening and loading on DNA. J Mol Biol (2011) 0.87
The RFC clamp loader: structure and function. Subcell Biochem (2012) 0.86
Nucleotide-induced conformational changes in an isolated Escherichia coli DNA polymerase III clamp loader subunit. Structure (2003) 0.85
Cultured gill epithelia as models for the freshwater fish gill. Biochim Biophys Acta (2002) 0.84
Resolving a fidelity paradox: why Escherichia coli DNA polymerase II makes more base substitution errors in AT- compared with GC-rich DNA. J Biol Chem (2001) 0.83
RuvA is a sliding collar that protects Holliday junctions from unwinding while promoting branch migration. J Mol Biol (2005) 0.82
The clamp loader assembles the beta clamp onto either a 3' or 5' primer terminus: the underlying basis favoring 3' loading. J Biol Chem (2009) 0.82
A single subunit directs the assembly of the Escherichia coli DNA sliding clamp loader. Structure (2010) 0.82
Mechanism of the delta wrench in opening the beta sliding clamp. J Biol Chem (2003) 0.82
DNA ligase: getting a grip to seal the deal. Curr Biol (2005) 0.81
Helical proteins initiate replication of DNA helices. Nat Struct Mol Biol (2006) 0.81
Protein trafficking on sliding clamps. Philos Trans R Soc Lond B Biol Sci (2004) 0.81
A novel function for the conserved glutamate residue in the walker B motif of replication factor C. Genes (Basel) (2013) 0.80
Rho factor: transcription termination in four steps. Curr Biol (2003) 0.78
A proposal: Source of single strand DNA that elicits the SOS response. Front Biosci (Landmark Ed) (2013) 0.78
Replisome Dynamics during Chromosome Duplication. Ecosal Plus (2009) 0.78
Structural biology. Getting DNA to unwind. Science (2007) 0.77
The ATP sites of AAA+ clamp loaders work together as a switch to assemble clamps on DNA. J Biol Chem (2014) 0.77
A consensus view of DNA binding by the C family of replicative DNA polymerases. Proc Natl Acad Sci U S A (2008) 0.77
Subunit sharing among high- and low-fidelity DNA polymerases. Proc Natl Acad Sci U S A (2012) 0.77
Polymerase trafficking: A role for transcription factors in preventing replication fork arrest. Transcription (2010) 0.76
Direct restart of a replication fork stalled by a head-on RNA polymerase. J Vis Exp (2010) 0.75
Possible psychotropic effects of Aripiprazole. Schizophr Res (2007) 0.75