Published in Crit Rev Food Sci Nutr on January 01, 2003
Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat Rev Cancer (2009) 3.90
Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem Pharmacol (2011) 2.74
Tea polyphenols for health promotion. Life Sci (2007) 2.50
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC Med Genomics (2009) 2.36
High-mobility group box 1, oxidative stress, and disease. Antioxid Redox Signal (2011) 2.19
The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention. Arch Biochem Biophys (2010) 1.98
Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice. Food Chem Toxicol (2009) 1.76
Call to action: cardiovascular disease in Asian Americans: a science advisory from the American Heart Association. Circulation (2010) 1.69
Coffee, tea, and incident type 2 diabetes: the Singapore Chinese Health Study. Am J Clin Nutr (2008) 1.68
The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity. Biochemistry (2010) 1.63
Green tea catechins and cardiovascular health: an update. Curr Med Chem (2008) 1.58
Risk of colon cancer and coffee, tea, and sugar-sweetened soft drink intake: pooled analysis of prospective cohort studies. J Natl Cancer Inst (2010) 1.47
Beneficial effects of green tea: a literature review. Chin Med (2010) 1.44
Tea Consumption and Cognitive Impairment: A Cross-Sectional Study among Chinese Elderly. PLoS One (2015) 1.44
STAT-1: a novel regulator of apoptosis. Int J Exp Pathol (2003) 1.43
Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination. Cancer Res (2007) 1.43
Complementary and alternative medicine for the treatment of type 2 diabetes. Can Fam Physician (2009) 1.40
First trimester coffee and tea intake and risk of gestational diabetes mellitus: a study within a national birth cohort. BJOG (2014) 1.39
Metabolic fate of polyphenols in the human superorganism. Proc Natl Acad Sci U S A (2010) 1.34
Acute EGCG supplementation reverses endothelial dysfunction in patients with coronary artery disease. J Am Coll Nutr (2007) 1.30
Laboratory, epidemiological, and human intervention studies show that tea (Camellia sinensis) may be useful in the prevention of obesity. J Nutr (2010) 1.29
Inhibition of carcinogenesis by tea constituents. Semin Cancer Biol (2007) 1.25
Exposure and toxicity of green tea polyphenols in fasted and non-fasted dogs. Toxicology (2009) 1.24
Associations between flavonoids and cardiovascular disease incidence or mortality in European and US populations. Nutr Rev (2012) 1.23
Neuroprotective molecular mechanisms of (-)-epigallocatechin-3-gallate: a reflective outcome of its antioxidant, iron chelating and neuritogenic properties. Genes Nutr (2009) 1.12
Antioxidative and anti-carcinogenic activities of tea polyphenols. Arch Toxicol (2008) 1.11
Epigallocatechin-gallate enhances the activity of tetracycline in staphylococci by inhibiting its efflux from bacterial cells. Antimicrob Agents Chemother (2004) 1.10
Randomized phase III clinical trial of five different arms of treatment in 332 patients with cancer cachexia. Oncologist (2010) 1.06
Prospective cohort study of tea consumption and risk of digestive system cancers: results from the Shanghai Women's Health Study. Am J Clin Nutr (2012) 1.02
Cancer prevention with promising natural products: mechanisms of action and molecular targets. Anticancer Agents Med Chem (2012) 1.01
Green tea polyphenol sensing. Proc Jpn Acad Ser B Phys Biol Sci (2011) 1.00
Autoxidative quinone formation in vitro and metabolite formation in vivo from tea polyphenol (-)-epigallocatechin-3-gallate: studied by real-time mass spectrometry combined with tandem mass ion mapping. Free Radic Biol Med (2007) 0.99
Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts. J Korean Med Sci (2010) 0.99
The challenge of developing green tea polyphenols as therapeutic agents. Inflammopharmacology (2008) 0.98
New insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancer. Nutr Cancer (2011) 0.98
Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways. Eur J Nutr (2013) 0.98
Beneficial Effects of Fermented Green Tea Extract in a Rat Model of Non-alcoholic Steatohepatitis. J Clin Biochem Nutr (2009) 0.96
Overview of major classes of plant-derived anticancer drugs. Int J Biomed Sci (2009) 0.96
Validation of green tea polyphenol biomarkers in a phase II human intervention trial. Food Chem Toxicol (2007) 0.96
Chronic Oral Epigallocatechin-gallate Alleviates Streptozotocin-induced Diabetic Neuropathic Hyperalgesia in Rat: Involvement of Oxidative Stress. Iran J Pharm Res (2012) 0.95
Does green tea affect postprandial glucose, insulin and satiety in healthy subjects: a randomized controlled trial. Nutr J (2010) 0.94
Green tea extract for periodontal health. J Indian Soc Periodontol (2011) 0.94
Sinecatechins: Effects on HPV-Induced Enzymes Involved in Inflammatory Mediator Generation. J Clin Aesthet Dermatol (2012) 0.94
Effects of black and green tea consumption on blood glucose levels in non-obese elderly men and women from Mediterranean Islands (MEDIS epidemiological study). Eur J Nutr (2008) 0.94
Associations of tea and coffee consumption with prostate cancer risk. Cancer Causes Control (2013) 0.94
Green tea seed oil reduces weight gain in C57BL/6J mice and influences adipocyte differentiation by suppressing peroxisome proliferator-activated receptor-gamma. Pflugers Arch (2008) 0.93
Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significantly correlated with cytochrome P450 suppression. World J Gastroenterol (2009) 0.92
Quantitative evaluation of the beneficial effects in the mdx mouse of epigallocatechin gallate, an antioxidant polyphenol from green tea. Histochem Cell Biol (2012) 0.92
Effect of green tea catechin, a local drug delivery system as an adjunct to scaling and root planing in chronic periodontitis patients: A clinicomicrobiological study. J Indian Soc Periodontol (2011) 0.91
Biochemical and transcriptome analyses of a novel chlorophyll-deficient chlorina tea plant cultivar. BMC Plant Biol (2014) 0.90
Catechin suppresses an array of signalling molecules and modulates alcohol-induced endotoxin mediated liver injury in a rat model. PLoS One (2011) 0.90
Chemoprevention of bladder cancer. World J Urol (2006) 0.90
Long-term tea intake is associated with reduced prevalence of (type 2) diabetes mellitus among elderly people from Mediterranean islands: MEDIS epidemiological study. Yonsei Med J (2009) 0.89
Green tea (Camellia sinensis) attenuates nephropathy by downregulating Nox4 NADPH oxidase in diabetic spontaneously hypertensive rats. J Nutr (2008) 0.89
Epigallocatechin Gallate: A Review of Its Beneficial Properties to Prevent Metabolic Syndrome. Nutrients (2015) 0.88
Epigallocatechin-3-gallate (EGCG) affects the antioxidant and immune defense of the rainbow trout, Oncorhynchus mykiss. Fish Physiol Biochem (2009) 0.87
Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies. J Med Chem (2009) 0.87
Epigallocatechin-3-gallate reduces airway inflammation in mice through binding to proinflammatory chemokines and inhibiting inflammatory cell recruitment. J Immunol (2011) 0.87
The effects of theaflavin-enriched black tea extract on muscle soreness, oxidative stress, inflammation, and endocrine responses to acute anaerobic interval training: a randomized, double-blind, crossover study. J Int Soc Sports Nutr (2010) 0.87
Effect of Grape Seed Extract and Quercetin on Cardiovascular and Endothelial Parameters in High-Risk Subjects. J Biomed Biotechnol (2004) 0.87
Epigenetic effects of green tea polyphenols in cancer. Epigenomics (2013) 0.87
Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance. Pharmacol Res (2010) 0.87
Cancer cachexia: medical management. Support Care Cancer (2009) 0.87
Green synthesis of platinum nanoparticles that induce cell death and G2/M-phase cell cycle arrest in human cervical cancer cells. J Mater Sci Mater Med (2015) 0.87
Combination therapy with epigallocatechin-3-gallate and doxorubicin in human prostate tumor modeling studies: inhibition of metastatic tumor growth in severe combined immunodeficiency mice. Am J Pathol (2010) 0.86
Theaflavin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-inflammatory effect and modulation of STAT-1. Mediators Inflamm (2006) 0.86
Protective effect of Pinus koraiensis needle water extract against oxidative stress in HepG2 cells and obese mice. J Med Food (2013) 0.85
Inhibition of proliferation of human lung cancer cells by green tea catechins is mediated by upregulation of let-7. Exp Ther Med (2012) 0.85
In vitro antifungal activity of epigallocatechin 3-O-gallate against clinical isolates of dermatophytes. Yonsei Med J (2011) 0.85
The effects of green tea on obesity and type 2 diabetes. Diabetes Metab J (2013) 0.85
Green tea polyphenol EGCG suppresses Wnt/β-catenin signaling by promoting GSK-3β- and PP2A-independent β-catenin phosphorylation/degradation. Biofactors (2014) 0.85
Pathobiology and chemoprevention of bladder cancer. J Oncol (2011) 0.84
Botanical compounds: effects on major eye diseases. Evid Based Complement Alternat Med (2013) 0.84
Antioxidant activities of licorice-derived prenylflavonoids. Nutr Res Pract (2012) 0.84
Implications of Green Tea and Its Constituents in the Prevention of Cancer via the Modulation of Cell Signalling Pathway. Biomed Res Int (2015) 0.84
Protective effects of green tea polyphenol against cisplatin-induced nephrotoxicity in rats. Obstet Gynecol Sci (2014) 0.83
Complexing of Green Tea Catechins with Food Constituents and Degradation of the Complexes by Lactobacillus plantarum. Biosci Microbiota Food Health (2012) 0.83
Relationship between gene expression and the accumulation of catechin during spring and autumn in tea plants (Camellia sinensis L.). Hortic Res (2015) 0.82
Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies. PLoS One (2010) 0.82
Natural compounds and aging: between autophagy and inflammasome. Biomed Res Int (2014) 0.82
Mitochondria: a new therapeutic target in chronic kidney disease. Nutr Metab (Lond) (2015) 0.82
(+)-Catechin protects dermal fibroblasts against oxidative stress-induced apoptosis. BMC Complement Altern Med (2014) 0.81
Effect of (-)-epigallocatechin-3-gallate on maintaining the periodontal ligament cell viability of avulsed teeth: a preliminary study. J Periodontal Implant Sci (2011) 0.81
Effects of water solutions on extracting green tea leaves. ScientificWorldJournal (2013) 0.81
Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties. FEBS Lett (2011) 0.80
Anticancer effect of black tea extract in human cancer cell lines. Springerplus (2015) 0.80
Optimal management for alcoholic liver disease: Conventional medications, natural therapy or combination? World J Gastroenterol (2016) 0.80
Beverage habits and mortality in Chinese adults. J Nutr (2015) 0.79
Epigallocatechin-3-gallate (EGCG) protects against chromate-induced toxicity in vitro. Toxicol Appl Pharmacol (2011) 0.79
Coffee and tea consumption in relation to prostate cancer prognosis. Cancer Causes Control (2013) 0.79
The microbiota is essential for the generation of black tea theaflavins-derived metabolites. PLoS One (2012) 0.79
Integrating cytosolic phospholipase A₂ with oxidative/nitrosative signaling pathways in neurons: a novel therapeutic strategy for AD. Mol Neurobiol (2012) 0.79
Treatment of cachexia in oncology. Indian J Palliat Care (2010) 0.79
Safety and chemopreventive effect of Polyphenon E in preventing early and metastatic progression of prostate cancer in TRAMP mice. Cancer Prev Res (Phila) (2014) 0.79
Structural identification of mouse fecal metabolites of theaflavin 3,3'-digallate using liquid chromatography tandem mass spectrometry. J Chromatogr A (2011) 0.79
Effect of epicatechin against radiation-induced oral mucositis: in vitro and in vivo study. PLoS One (2013) 0.79
Neuroprotective effect of tea polyphenols on oxyhemoglobin induced subarachnoid hemorrhage in mice. Oxid Med Cell Longev (2013) 0.79
Anti-inflammatory effect of (-)-epigallocatechin-3-gallate on Porphyromonas gingivalis lipopolysaccharide-stimulated fibroblasts and stem cells derived from human periodontal ligament. J Periodontal Implant Sci (2012) 0.78
A new proposed guidance system for beverage consumption in the United States. Am J Clin Nutr (2006) 4.12
Effect of vitamins C and E on progression of transplant-associated arteriosclerosis: a randomised trial. Lancet (2002) 3.03
Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr (2006) 2.72
Vitamins E and C are safe across a broad range of intakes. Am J Clin Nutr (2005) 2.72
Anthocyanins, phenolics, and antioxidant capacity in diverse small fruits: vaccinium, rubus, and ribes. J Agric Food Chem (2002) 2.70
Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway. Proc Natl Acad Sci U S A (2007) 1.95
Uric acid as a CNS antioxidant. J Alzheimers Dis (2010) 1.93
Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon? Free Radic Biol Med (2006) 1.85
Selective vulnerability of preterm white matter to oxidative damage defined by F2-isoprostanes. Ann Neurol (2005) 1.77
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells. Cardiovasc Res (2002) 1.63
Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment. Exp Neurol (2003) 1.30
Obesity and oxidative stress: a direct link to CVD? Arterioscler Thromb Vasc Biol (2003) 1.25
Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo. Free Radic Biol Med (2008) 1.23
Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes. Anal Biochem (2006) 1.21
Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice. Circulation (2007) 1.21
Metal-independent production of hydroxyl radicals by halogenated quinones and hydrogen peroxide: an ESR spin trapping study. Free Radic Biol Med (2002) 1.20
Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects. Free Radic Biol Med (2004) 1.10
Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties. Free Radic Biol Med (2011) 1.06
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism. J Biol Chem (2006) 1.05
Endurance exercise results in DNA damage as detected by the comet assay. Free Radic Biol Med (2004) 1.04
Color and antioxidant properties of cyanidin-based anthocyanin pigments. J Agric Food Chem (2002) 1.02
Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function. Annu Rev Nutr (2013) 1.02
Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity. J Agric Food Chem (2012) 1.00
Mechanism of metal-independent decomposition of organic hydroperoxides and formation of alkoxyl radicals by halogenated quinones. Proc Natl Acad Sci U S A (2007) 0.99
Ascorbic acid and rates of cognitive decline in Alzheimer's disease. J Alzheimers Dis (2009) 0.98
Positive correlation between circulating cathelicidin antimicrobial peptide (hCAP18/LL-37) and 25-hydroxyvitamin D levels in healthy adults. BMC Res Notes (2012) 0.97
Effects of black tea consumption on plasma catechins and markers of oxidative stress and inflammation in patients with coronary artery disease. Free Radic Biol Med (2005) 0.96
Enough is enough. Ann Intern Med (2014) 0.94
The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice. Exp Biol Med (Maywood) (2010) 0.93
Reliability and validity of food frequency questionnaire and nutrient biomarkers in elders with and without mild cognitive impairment. Alzheimer Dis Assoc Disord (2011) 0.93
The increase in human plasma antioxidant capacity after apple consumption is due to the metabolic effect of fructose on urate, not apple-derived antioxidant flavonoids. Free Radic Biol Med (2004) 0.92
Efficacy of Multivitamin/mineral Supplementation to Reduce Chronic Disease Risk: A Critical Review of the Evidence from Observational Studies and Randomized Controlled Trials. Crit Rev Food Sci Nutr (2015) 0.92
Why clinical trials of vitamin E and cardiovascular diseases may be fatally flawed. Commentary on "The relationship between dose of vitamin E and suppression of oxidative stress in humans". Free Radic Biol Med (2007) 0.90
Vitamin E revisited: do new data validate benefits for chronic disease prevention? Curr Opin Lipidol (2008) 0.89
Antioxidants in Alzheimer's disease-vitamin C delivery to a demanding brain. J Alzheimers Dis (2003) 0.88
Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation. Free Radic Biol Med (2006) 0.88
Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine. Arterioscler Thromb Vasc Biol (2009) 0.88
Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity. Arterioscler Thromb Vasc Biol (2006) 0.88
Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research. Nutrients (2013) 0.86
Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells. Free Radic Biol Med (2003) 0.86
Short-term and long-term vitamin C supplementation in humans dose-dependently increases the resistance of plasma to ex vivo lipid peroxidation. Arch Biochem Biophys (2004) 0.86
Ascorbate does not act as a pro-oxidant towards lipids and proteins in human plasma exposed to redox-active transition metal ions and hydrogen peroxide. Free Radic Biol Med (2003) 0.86
Ergothioneine prevents copper-induced oxidative damage to DNA and protein by forming a redox-inactive ergothioneine-copper complex. Chem Res Toxicol (2010) 0.85
Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation. Ann N Y Acad Sci (2010) 0.84
R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles. Am J Physiol Regul Integr Comp Physiol (2011) 0.84
Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex. Free Radic Biol Med (2002) 0.84
Dihydrolipoic acid lowers the redox activity of transition metal ions but does not remove them from the active site of enzymes. Redox Rep (2004) 0.84
Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo. Am J Physiol Heart Circ Physiol (2011) 0.84
Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status. Redox Rep (2002) 0.83
Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues. Free Radic Biol Med (2011) 0.83
Is there a gender difference in the effect of antioxidants on cancer risk? Br J Nutr (2005) 0.82
A purified feverfew extract protects from oxidative damage by inducing DNA repair in skin cells via a PI3-kinase-dependent Nrf2/ARE pathway. J Dermatol Sci (2013) 0.82
Peroxynitrite-induced oxidation of plasma lipids is enhanced in stable hemodialysis patients. Kidney Int (2003) 0.82
Vitamin C. Adv Nutr (2014) 0.81
Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: the role of vitamin C. Biol Chem (2002) 0.81
Inhibition of peroxynitrite-mediated LDL oxidation by prenylated flavonoids: the alpha,beta-unsaturated keto functionality of 2'-hydroxychalcones as a novel antioxidant pharmacophore. Chem Res Toxicol (2003) 0.80
Retracted Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma. Proc Natl Acad Sci U S A (2004) 0.80
Vitamins E and C in the prevention of cardiovascular disease and cancer in men. Free Radic Biol Med (2009) 0.80
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage. FEBS Lett (2002) 0.80
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice. Atherosclerosis (2012) 0.79
A new twist on an old vitamin: human polymorphisms in the gene encoding the sodium-dependent vitamin C transporter 1. Am J Clin Nutr (2010) 0.78
To C or not to C, that is the question! J Am Coll Cardiol (2003) 0.77
Protection by tropolones against H2O2-induced DNA damage and apoptosis in cultured Jurkat cells. Free Radic Res (2005) 0.77
Mouse cerebral prostaglandins, but not oxidative damage, change with age and are responsive to indomethacin treatment. Brain Res (2002) 0.76
Bcl-2 overexpression inhibits tetrachlorohydroquinone-induced apoptosis in NIH3T3 cells: a possible mechanism for tumor promotion. Mol Carcinog (2004) 0.76
Retraction: "Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma". Proc Natl Acad Sci U S A (2007) 0.75
Lack of inhibitory effect of HDL on TNFalpha-induced adhesion molecule expression in human aortic endothelial cells. Atherosclerosis (2002) 0.75
Micronutrient concentrations and subclinical atherosclerosis in adults with HIV. Am J Clin Nutr (2010) 0.75
Effects of different organic weed management strategies on the physicochemical, sensory, and antioxidant properties of machine-harvested blackberry fruits. J Food Sci (2014) 0.75
Ascorbylated 4-hydroxy-2-nonenal as a potential biomarker of oxidative stress response. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.75
An error in the US Department of Agriculture nutrient database results in vitamin A values that are 6 times too high. Am J Clin Nutr (2008) 0.75
Vascular basis for the treatment of myocardial ischemia study: trial design and baseline characteristics. Am Heart J (2004) 0.75
Copper induces--and copper chelation by tetrathiomolybdate inhibits--endothelial activation in vitro. Redox Rep (2013) 0.75