Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies.

PubWeight™: 0.82‹?›

🔗 View Article (PMC 2916818)

Published in PLoS One on August 05, 2010

Authors

Ki Sung Kang1, Yujing Wen, Noriko Yamabe, Masayuki Fukui, Stephanie C Bishop, Bao Ting Zhu

Author Affiliations

1: Department of Pharmacology, Toxicology and Therapeutics, School of Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America.

Articles cited by this

NF-kappaB activation by reactive oxygen species: fifteen years later. Biochem Pharmacol (2006) 5.25

Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res (2000) 4.82

Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors. Pharmacol Rev (1999) 3.81

Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. Crit Rev Food Sci Nutr (2003) 3.75

Description of Parkinson's disease as a clinical syndrome. Ann N Y Acad Sci (2003) 3.15

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron (1989) 3.06

Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov Disord (2001) 2.89

Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clin Cancer Res (2003) 2.80

Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance. Ann N Y Acad Sci (2008) 1.92

Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E. Cancer Epidemiol Biomarkers Prev (2001) 1.87

The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice. J Nutr (2008) 1.82

Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate. Drug Metab Dispos (2003) 1.74

Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells. J Neurochem (1998) 1.72

Kainic acid seizures in the rat. Prog Neurobiol (1994) 1.70

Absorption, distribution, elimination of tea polyphenols in rats. Drug Metab Dispos (1997) 1.69

Immediate-release and controlled-release carbidopa/levodopa in PD: a 5-year randomized multicenter study. Carbidopa/Levodopa Study Group. Neurology (1999) 1.67

Catechol-O-Methyltransferase (COMT)-mediated methylation metabolism of endogenous bioactive catechols and modulation by endobiotics and xenobiotics: importance in pathophysiology and pathogenesis. Curr Drug Metab (2002) 1.62

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: dermal, acute and short-term toxicity studies. Food Chem Toxicol (2006) 1.48

Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells. Eur J Pharmacol (2009) 1.48

Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue. Carcinogenesis (1998) 1.44

Parkinson's disease is associated with hippocampal atrophy. Mov Disord (2003) 1.37

Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate. FASEB J (2003) 1.31

Degeneration of hippocampal CA3 pyramidal cells induced by intraventricular kainic acid. J Comp Neurol (1980) 1.23

Decarboxylase inhibitors. Pharmacol Ther B (1975) 1.15

Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high-performance liquid chromatography with electrochemical detection. J Neurochem (1982) 1.12

Catechin content of 18 teas and a green tea extract supplement correlates with the antioxidant capacity. Nutr Cancer (2003) 1.11

Progress in Parkinson's disease-where do we stand? Prog Neurobiol (2008) 1.10

O-Methylation of tea polyphenols catalyzed by human placental cytosolic catechol-O-methyltransferase. Drug Metab Dispos (2000) 1.06

Green tea (-)-epigallocatechin-3-gallate inhibits beta-amyloid-induced cognitive dysfunction through modification of secretase activity via inhibition of ERK and NF-kappaB pathways in mice. J Nutr (2009) 1.05

The effect of catechol-O-methyl transferase inhibition by entacapone on the pharmacokinetics and metabolism of levodopa in healthy volunteers. Clin Neuropharmacol (1993) 1.05

Coffee and tea consumption and the risk of Parkinson's disease. Mov Disord (2007) 1.04

Biochemical and pharmacological properties of a peripherally acting catechol-O-methyltransferase inhibitor entacapone. Naunyn Schmiedebergs Arch Pharmacol (1992) 1.03

Strong inhibitory effects of common tea catechins and bioflavonoids on the O-methylation of catechol estrogens catalyzed by human liver cytosolic catechol-O-methyltransferase. Drug Metab Dispos (2004) 1.01

Levodopa-induced changes in synaptic dopamine in patients with Parkinson's disease as measured by [11C]raclopride displacement and PET. Neurology (1996) 1.00

Smoking and tea consumption delay onset of Parkinson's disease. Parkinsonism Relat Disord (2008) 0.97

Effect of tolcapone on plasma levodopa concentrations after coadministration with levodopa/carbidopa to healthy volunteers. Clin Neuropharmacol (1997) 0.95

Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum. J Neurochem (1993) 0.94

Modified high-performance liquid chromatography with electrochemical detection method for plasma measurement of levodopa, 3-O-methyldopa, dopamine, carbidopa and 3,4-dihydroxyphenyl acetic acid. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.93

Molecular modelling study of the mechanism of high-potency inhibition of human catechol-O-methyltransferase by (-)-epigallocatechin-3-O-gallate. Xenobiotica (2008) 0.92

Kainic acid-induced activation of nuclear factor-kappaB in rat hippocampus. Exp Brain Res (1999) 0.92

Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes. Br J Pharmacol (2001) 0.90

3-methoxy-4-hydroxyphenylalanine (3-O-methyldopa) in plasma during oral L-dopa therapy of patients with Parkinson's disease. Clin Chim Acta (1972) 0.89

The pharmacology of Parkinson's disease: basic aspects and recent advances. Experientia (1984) 0.89

Extracellular concentrations of dopamine and metabolites in the rat caudate after oral administration of a novel catechol-O-methyltransferase inhibitor Ro 40-7592. J Neurochem (1992) 0.89

Biochemical and molecular modeling studies of the O-methylation of various endogenous and exogenous catechol substrates catalyzed by recombinant human soluble and membrane-bound catechol-O-methyltransferases. Chem Res Toxicol (2007) 0.89

Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate. Neurotoxicology (2002) 0.89

Lovastatin modulates increased cholesterol and oxysterol levels and has a neuroprotective effect on rat hippocampal neurons after kainate injury. J Neuropathol Exp Neurol (2006) 0.88

The significance of 3-O-methyldopa concentrations in the cerebrospinal fluid in the pathogenesis of wearing-off phenomenon in Parkinson's disease. Neurosci Lett (1991) 0.87

Effects of tea polyphenols and flavonoids on liver microsomal glucuronidation of estradiol and estrone. J Steroid Biochem Mol Biol (1998) 0.86

EGCG protects HT-22 cells against glutamate-induced oxidative stress. Neurotox Res (2006) 0.86

Issues important for rational COMT inhibition. Neurology (2000) 0.84

Parkinson's disease and dementia. Neurol Sci (2006) 0.83

Plasma O-methyldopa in levodopa-induced dyskinesias. A bioclinical investigation. Acta Neurol Scand (1977) 0.83

Melatonin maintains glutathione homeostasis in kainic acid-exposed rat brain tissues. FASEB J (1997) 0.83

Emerging drugs for Parkinson's disease. Expert Opin Emerg Drugs (2006) 0.82

The role of 3-O-methyldopa in the side effects of L-dopa. Neurochem Res (2007) 0.82

The effects of different repeated doses of entacapone on the pharmacokinetics of L-Dopa and on the clinical response to L-Dopa in Parkinson's disease. Clin Neuropharmacol (2001) 0.81

CNS dopamine oxidation and catechol-O-methyltransferase: importance in the etiology, pharmacotherapy, and dietary prevention of Parkinson's disease. Int J Mol Med (2004) 0.81

Protection against kainate neurotoxicity by ginsenosides: attenuation of convulsive behavior, mitochondrial dysfunction, and oxidative stress. J Neurosci Res (2009) 0.81

Effects of peripheral and central catechol-O-methyltransferase inhibition on striatal extracellular levels of dopamine: a microdialysis study in freely moving rats. Parkinsonism Relat Disord (2003) 0.80

Hepatotoxic profile of catechol-O-methyltransferase inhibitors in Parkinson's disease. Expert Opin Drug Saf (2003) 0.78

Oral pre-treatment with epigallocatechin gallate in 6-OHDA lesioned rats produces subtle symptomatic relief but not neuroprotection. Brain Res Bull (2009) 0.78

The place of COMT inhibitors in the armamentarium of drugs for the treatment of Parkinson's disease. Neurology (2000) 0.78

Articles by these authors

Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids. Mol Pharmacol (2005) 1.78

Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms. Endocrinology (2003) 1.77

Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols. Carcinogenesis (2005) 1.60

Quantitative structure-activity relationship of various endogenous estrogen metabolites for human estrogen receptor alpha and beta subtypes: Insights into the structural determinants favoring a differential subtype binding. Endocrinology (2006) 1.57

Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells. Eur J Pharmacol (2009) 1.48

DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells. Nucleic Acids Res (2009) 1.23

Involvement of IL-17 in Fas ligand-induced inflammation. Int Immunol (2004) 1.22

Docosahexaenoic acid induces apoptosis in MCF-7 cells in vitro and in vivo via reactive oxygen species formation and caspase 8 activation. PLoS One (2010) 1.16

Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death. Free Radic Biol Med (2010) 1.13

Mitochondrial superoxide dismutase SOD2, but not cytosolic SOD1, plays a critical role in protection against glutamate-induced oxidative stress and cell death in HT22 neuronal cells. Free Radic Biol Med (2010) 1.12

Neuronal gap junctions are required for NMDA receptor-mediated excitotoxicity: implications in ischemic stroke. J Neurophysiol (2010) 1.10

Fas ligand induces cell-autonomous NF-kappaB activation and interleukin-8 production by a mechanism distinct from that of tumor necrosis factor-alpha. J Biol Chem (2004) 1.10

Indoleamine 2,3-dioxygenase tissue distribution and cellular localization in mice: implications for its biological functions. J Histochem Cytochem (2009) 1.09

ESR study on the structure and hydroxyl radical-scavenging activity relationships of ginsenosides isolated from Panax ginseng C A Meyer. Biol Pharm Bull (2007) 1.09

Concentration-dependent mitogenic and antiproliferative actions of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells. J Steroid Biochem Mol Biol (2004) 1.04

Effects of heat-processed ginseng and its active component ginsenoside 20(S)-Rg3 on the progression of renal damage and dysfunction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty rats. Biol Pharm Bull (2010) 1.03

Strong inhibitory effects of common tea catechins and bioflavonoids on the O-methylation of catechol estrogens catalyzed by human liver cytosolic catechol-O-methyltransferase. Drug Metab Dispos (2004) 1.01

Heat-processed Panax ginseng and diabetic renal damage: active components and action mechanism. J Ginseng Res (2013) 1.01

EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: role of ROS accumulation, caspase-8 activation, and autophagy induction. J Cell Biochem (2013) 0.99

Resveratrol attenuates the anticancer efficacy of paclitaxel in human breast cancer cells in vitro and in vivo. Eur J Cancer (2010) 0.99

Efficient thermal deglycosylation of ginsenoside Rd and its contribution to the improved anticancer activity of ginseng. J Agric Food Chem (2013) 0.97

Increase in the free radical scavenging activities of American ginseng by heat processing and its safety evaluation. J Ethnopharmacol (2007) 0.97

Therapeutic potential of 20(S)-ginsenoside Rg(3) against streptozotocin-induced diabetic renal damage in rats. Eur J Pharmacol (2008) 0.96

Protective effects of morroniside isolated from Corni Fructus against renal damage in streptozotocin-induced diabetic rats. Biol Pharm Bull (2008) 0.95

Protective effect of sun ginseng against diabetic renal damage. Biol Pharm Bull (2006) 0.95

Role of cyclin B1/Cdc2 up-regulation in the development of mitotic prometaphase arrest in human breast cancer cells treated with nocodazole. PLoS One (2011) 0.95

Amelioration of diabetic nephropathy by dried Rehmanniae Radix (Di Huang) extract. Am J Chin Med (2004) 0.94

A study on the effects to diabetic nephropathy of Hachimi-jio-gan in rats. Nephron Exp Nephrol (2004) 0.94

Induction of a reversible, non-cytotoxic S-phase delay by resveratrol: implications for a mechanism of lifespan prolongation and cancer protection. Br J Pharmacol (2009) 0.92

Protective effect of heat-processed American ginseng against diabetic renal damage in rats. J Agric Food Chem (2007) 0.91

Mechanism of 2-methoxyestradiol-induced apoptosis and growth arrest in human breast cancer cells. Mol Carcinog (2009) 0.91

Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro. J Steroid Biochem Mol Biol (2006) 0.90

Hepatocyte tissue factor activates the coagulation cascade in mice. Blood (2013) 0.90

Beneficial effect of 17β-estradiol on hyperglycemia and islet β-cell functions in a streptozotocin-induced diabetic rat model. Toxicol Appl Pharmacol (2010) 0.90

Biochemical and molecular modeling studies of the O-methylation of various endogenous and exogenous catechol substrates catalyzed by recombinant human soluble and membrane-bound catechol-O-methyltransferases. Chem Res Toxicol (2007) 0.89

Protein disulfide isomerase is a multifunctional regulator of estrogenic status in target cells. J Steroid Biochem Mol Biol (2008) 0.89

Critical role of the JNK-p53-GADD45α apoptotic cascade in mediating oxidative cytotoxicity in hippocampal neurons. Br J Pharmacol (2011) 0.89

Rapid generation of mitochondrial superoxide induces mitochondrion-dependent but caspase-independent cell death in hippocampal neuronal cells that morphologically resembles necroptosis. Toxicol Appl Pharmacol (2012) 0.88

Long-term treatment with Hachimi-jio-gan attenuates kidney damage in spontaneously diabetic WBN/Kob rats. J Pharm Pharmacol (2005) 0.88

Pancreas-specific protein disulfide isomerase has a cell type-specific expression in various mouse tissues and is absent in human pancreatic adenocarcinoma cells: implications for its functions. J Mol Histol (2009) 0.87

Human pancreas-specific protein disulfide isomerase homolog (PDIp) is an intracellular estrogen-binding protein that modulates estrogen levels and actions in target cells. J Steroid Biochem Mol Biol (2009) 0.87

Human pancreas-specific protein disulfide-isomerase (PDIp) can function as a chaperone independently of its enzymatic activity by forming stable complexes with denatured substrate proteins. Biochem J (2010) 0.87

Suppression of T-cell response and prolongation of allograft survival in a rat model by tryptophan catabolites. Eur J Pharmacol (2009) 0.86

In vitro and in vivo estrogenic activity of chlorinated derivatives of bisphenol A. Toxicology (2005) 0.86

Protective effects of the Chinese prescription Hachimi-jio-gan against diabetic oxidative stress. J Pharm Pharmacol (2004) 0.86

The beneficial effects of morroniside on the inflammatory response and lipid metabolism in the liver of db/db mice. Biol Pharm Bull (2009) 0.85

Selective insensitivity of ZR-75-1 human breast cancer cells to 2-methoxyestradiol: evidence for type II 17beta-hydroxysteroid dehydrogenase as the underlying cause. Cancer Res (2005) 0.85

Comparison of the effects of Korean ginseng and heat-processed Korean ginseng on diabetic oxidative stress. Am J Chin Med (2008) 0.85

Critical role of cyclin B1/Cdc2 up-regulation in the induction of mitotic prometaphase arrest in human breast cancer cells treated with 2-methoxyestradiol. Biochim Biophys Acta (2012) 0.85

Structural basis for certain naturally occurring bioflavonoids to function as reducing co-substrates of cyclooxygenase I and II. PLoS One (2010) 0.84

Characterization of the estradiol-binding site structure of human protein disulfide isomerase (PDI). PLoS One (2011) 0.84

Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol. Cancer Res (2003) 0.84

NADPH-dependent metabolism of estrone by human liver microsomes. J Pharmacol Exp Ther (2002) 0.84

Strong activation of cyclooxygenase I and II catalytic activity by dietary bioflavonoids. J Lipid Res (2008) 0.84

Mechanism of dinitrochlorobenzene-induced dermatitis in mice: role of specific antibodies in pathogenesis. PLoS One (2009) 0.83

Stereospecificity in hydroxyl radical scavenging activities of four ginsenosides produced by heat processing. Bioorg Med Chem Lett (2006) 0.83

Prolongation of rat major histocompatibility complex-compatible cardiac allograft survival during pregnancy. J Heart Lung Transplant (2009) 0.83

Synthesis of 7alpha-substituted derivatives of 17beta-estradiol. Steroids (2006) 0.83

Renoprotective effects of Maillard reaction products generated during heat treatment of ginsenoside Re with leucine. Food Chem (2013) 0.82

Inhibition of human catechol-O-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee. J Steroid Biochem Mol Biol (2008) 0.82

Physiologic levels of 2-methoxyestradiol interfere with nongenomic signaling of 17beta-estradiol in human breast cancer cells. Clin Cancer Res (2006) 0.82

Ectoadenylate kinase and plasma membrane ATP synthase activities of human vascular endothelial cells. J Biol Chem (2006) 0.82

Preventive effect of 20(S)-ginsenoside Rg3 against lipopolysaccharide-induced hepatic and renal injury in rats. Free Radic Res (2007) 0.82

Synergism between the anticancer actions of 2-methoxyestradiol and microtubule-disrupting agents in human breast cancer. Cancer Res (2005) 0.82

Anticarcinogenic effects of products of heat-processed ginsenoside Re, a major constituent of ginseng berry, on human gastric cancer cells. J Agric Food Chem (2014) 0.81

Characterization of the estradiol-binding site structure of human pancreas-specific protein disulfide isomerase: indispensable role of the hydrogen bond between His278 and the estradiol 3-hydroxyl group. Biochemistry (2010) 0.81

Beneficial effect of 7-O-galloyl-D-sedoheptulose on oxidative stress and hepatic and renal changes in type 2 diabetic db/db mice. Eur J Pharmacol (2010) 0.81

Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies. J Pharm Pharmacol (2008) 0.81

Growth-stimulatory effect of resveratrol in human cancer cells. Mol Carcinog (2010) 0.81

Characterization of the oestrogenic activity of non-aromatic steroids: are there male-specific endogenous oestrogen receptor modulators? Br J Pharmacol (2009) 0.80

The protective role of Kangen-karyu against fructose-induced metabolic syndrome in a rat model. J Pharm Pharmacol (2007) 0.80

Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration. Brain Res (2012) 0.80

Inhibitory effects of ginseng sapogenins on the proliferation of triple negative breast cancer MDA-MB-231 cells. Bioorg Med Chem Lett (2014) 0.80

Human pancreas-specific protein disulfide isomerase homolog (PDIp) is redox-regulated through formation of an inter-subunit disulfide bond. Arch Biochem Biophys (2009) 0.80

Chemical synthesis and biochemical characterization of a biotinylated derivative of 17beta-estradiol with a long side chain covalently attached to its C-7alpha position. Steroids (2008) 0.79

Dendrobium moniliforme attenuates high-fat diet-induced renal damage in mice through the regulation of lipid-induced oxidative stress. Am J Chin Med (2012) 0.79

Kangen-karyu improves memory deficit caused by aging through normalization of neuro-plasticity-related signaling system and VEGF system in the brain. J Ethnopharmacol (2010) 0.79

Unique effect of the pregnancy hormone estriol on antigen-induced production of specific antibodies in female BALB/c mice. Steroids (2007) 0.79

NADPH-dependent formation of polar and nonpolar estrogen metabolites following incubations of 17 beta-estradiol with human liver microsomes. Drug Metab Dispos (2004) 0.78

Role of cyclin B1/Cdc2 in mediating Bcl-XL phosphorylation and apoptotic cell death following nocodazole-induced mitotic arrest. Mol Carcinog (2012) 0.78

Estriol has different effects from 17β-estradiol in modulating mouse splenocyte function under inflammatory conditions. J Immunotoxicol (2011) 0.78

Attenuating effects of wen-pi-tang treatment in rats with diabetic nephropathy. Am J Chin Med (2006) 0.78

Chinese prescription Kangen-karyu prevents dyslipidaemia and oxidative stress in mouse model of type 2 diabetes. J Pharm Pharmacol (2010) 0.78

Effect of clofibrate administration on the esterification and deesterification of steroid hormones by liver and extrahepatic tissues in rats. Biochem Pharmacol (2002) 0.78

Naturally-occurring estradiol-17beta-fatty acid esters, but not estradiol-17beta, preferentially induce mammary tumorigenesis in female rats: implications for an important role in human breast cancer. Toxicol Appl Pharmacol (2008) 0.77

Synthesis of novel estrogen receptor antagonists using metal-catalyzed coupling reactions and characterization of their biological activity. J Med Chem (2013) 0.77

Characterization of a novel human catechol-O-methyl-transferase mutant with triplet point mutations. Int J Mol Med (2008) 0.77