Published in Cell Motil Cytoskeleton on March 01, 2003
Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structures. Am J Physiol Heart Circ Physiol (2006) 2.37
Zasp is required for the assembly of functional integrin adhesion sites. J Cell Biol (2007) 1.46
Shuttling of the chaperones Unc45b and Hsp90a between the A band and the Z line of the myofibril. J Cell Biol (2008) 1.24
Myocyte remodeling in response to hypertrophic stimuli requires nucleocytoplasmic shuttling of muscle LIM protein. J Mol Cell Cardiol (2009) 1.04
Towards standardization of RNA quality assessment using user-independent classifiers of microcapillary electrophoresis traces. Nucleic Acids Res (2005) 7.63
Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol (2004) 7.17
The LIM domain: from the cytoskeleton to the nucleus. Nat Rev Mol Cell Biol (2004) 4.40
Striated muscle cytoarchitecture: an intricate web of form and function. Annu Rev Cell Dev Biol (2002) 3.66
Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement. J Cell Biol (2005) 3.13
Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors. Dev Cell (2003) 2.28
The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res (2007) 2.07
Reference values for vastus lateralis fiber size and type in healthy subjects over 40 years old: a systematic review and metaanalysis. J Appl Physiol (1985) (2013) 2.02
The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion. J Biol Chem (2003) 1.97
The Rho/Rac-family guanine nucleotide exchange factor VAV-1 regulates rhythmic behaviors in C. elegans. Cell (2005) 1.93
Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling. J Cell Biol (2006) 1.83
Deciphering cellular states of innate tumor drug responses. Genome Biol (2006) 1.83
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
The road from systems biology to systems medicine. Pediatr Res (2013) 1.70
Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. Proc Natl Acad Sci U S A (2005) 1.67
Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers. J Biol Chem (2002) 1.62
A zyxin-mediated mechanism for actin stress fiber maintenance and repair. Dev Cell (2010) 1.62
Revolutionizing medicine in the 21st century through systems approaches. Biotechnol J (2012) 1.60
Targeted disruption of the murine zyxin gene. Mol Cell Biol (2003) 1.51
From the membrane to the nucleus and back again: bifunctional focal adhesion proteins. Curr Opin Cell Biol (2006) 1.47
Doing (F/L)PPPPs: EVH1 domains and their proline-rich partners in cell polarity and migration. Curr Opin Cell Biol (2002) 1.41
The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms. Nucleic Acids Res (2005) 1.39
HNF1alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP-1 and carbohydrate-response element-binding protein (ChREBP) activation. J Biol Chem (2007) 1.36
Analysis of PINCH function in Drosophila demonstrates its requirement in integrin-dependent cellular processes. Development (2003) 1.36
Application of 'omics technologies to biomarker discovery in inflammatory lung diseases. Eur Respir J (2013) 1.19
Characterization of RACK1 function in Drosophila development. Dev Dyn (2007) 1.16
'The 39 steps' in gene expression profiling: critical issues and proposed best practices for microarray experiments. Drug Discov Today (2005) 1.15
The integrin effector PINCH regulates JNK activity and epithelial migration in concert with Ras suppressor 1. J Cell Biol (2004) 1.15
Personalized respiratory medicine: exploring the horizon, addressing the issues. Summary of a BRN-AJRCCM workshop held in Barcelona on June 12, 2014. Am J Respir Crit Care Med (2015) 1.12
Supervillin modulation of focal adhesions involving TRIP6/ZRP-1. J Cell Biol (2006) 1.11
Opposing roles of zyxin/LPP ACTA repeats and the LIM domain region in cell-cell adhesion. J Biol Chem (2006) 1.11
Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators. Mol Biol Cell (2012) 1.10
Bridging the gap between systems biology and medicine. Genome Med (2009) 1.07
The beta-catenin pathway is activated in focal nodular hyperplasia but not in cirrhotic FNH-like nodules. J Hepatol (2008) 1.06
Protein subnetwork markers improve prediction of cancer outcome. Mol Syst Biol (2007) 1.05
The Drosophila muscle LIM protein, Mlp84B, cooperates with D-titin to maintain muscle structural integrity. J Cell Sci (2007) 1.05
The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function. J Exp Biol (2008) 1.01
LPP, a LIM protein highly expressed in smooth muscle. Am J Physiol Cell Physiol (2003) 0.99
Computational disease modeling - fact or fiction? BMC Syst Biol (2009) 0.98
A functional and regulatory network associated with PIP expression in human breast cancer. PLoS One (2009) 0.96
Mitochondria-cytoskeleton interaction: distribution of β-tubulins in cardiomyocytes and HL-1 cells. Biochim Biophys Acta (2011) 0.96
TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness. FASEB J (2008) 0.96
Scale relativity theory and integrative systems biology: 2. Macroscopic quantum-type mechanics. Prog Biophys Mol Biol (2007) 0.94
Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar. J Allergy Clin Immunol (2012) 0.93
Molecular characterization of the Caenorhabditis elegans ALP/Enigma gene alp-1. Dev Dyn (2006) 0.93
The LIM Protein Zyxin Binds CARP-1 and Promotes Apoptosis. Genes Cancer (2010) 0.93
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs. Cancer Res (2009) 0.92
Molecular and phylogenetic characterization of Zyx102, a Drosophila orthologue of the zyxin family that interacts with Drosophila Enabled. Gene (2003) 0.92
The ALP-Enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans. Mol Biol Cell (2009) 0.91
Characterization of a new human isoform of the enigma homolog family specifically expressed in skeletal muscle. Biochem Biophys Res Commun (2004) 0.91
Complementary DNA arrays identify CD63 tetraspanin and alpha3 integrin chain as differentially expressed in low and high metastatic human colon carcinoma cells. Lab Invest (2002) 0.91
Drug specific resistance to oxaliplatin is associated with apoptosis defect in a cellular model of colon carcinoma. FEBS Lett (2002) 0.89
P4 medicine needs P4 education. Curr Pharm Des (2014) 0.89
Lateral communication between stress fiber sarcomeres facilitates a local remodeling response. Biophys J (2012) 0.89
The cytoskeletal regulator zyxin is required for viability in Drosophila melanogaster. Anat Rec (Hoboken) (2010) 0.89
A novel role for keratin 17 in coordinating oncogenic transformation and cellular adhesion in Ewing sarcoma. Mol Cell Biol (2013) 0.89
The EWS/FLI Oncogene Drives Changes in Cellular Morphology, Adhesion, and Migration in Ewing Sarcoma. Genes Cancer (2012) 0.88
Gene expression profiling of human satellite cells during muscular aging using cDNA arrays. Gene (2003) 0.86
Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays. Genome Biol (2002) 0.85
Transcriptome analysis of two bovine muscles during ontogenesis. J Biochem (2003) 0.85
Transforming growth factor-beta1-modulated cerebral gene expression. J Cereb Blood Flow Metab (2002) 0.84
Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008). Mol Oncol (2008) 0.84
Integration of Myeloblastosis Associated Virus proviral sequences occurs in the vicinity of genes encoding signaling proteins and regulators of cell proliferation. Cell Commun Signal (2006) 0.83
LIM domains target actin regulators paxillin and zyxin to sites of stress fiber strain. PLoS One (2013) 0.83
Editorial: Systems biology and personalized medicine - the future is now. Biotechnol J (2012) 0.83
Loss of the serum response factor cofactor, cysteine-rich protein 1, attenuates neointima formation in the mouse. Arterioscler Thromb Vasc Biol (2010) 0.83
A crucial role for Ras suppressor-1 (RSU-1) revealed when PINCH and ILK binding is disrupted. J Cell Sci (2012) 0.83
The cytoskeleton-associated PDZ-LIM protein, ALP, acts on serum response factor activity to regulate muscle differentiation. Mol Biol Cell (2007) 0.83
A transgenic mouse model engineered to investigate human brain-derived neurotrophic factor in vivo. Transgenic Res (2007) 0.82
Systems medicine approaches for the definition of complex phenotypes in chronic diseases and ageing. From concept to implementation and policies. Curr Pharm Des (2014) 0.82
Expression of the gene encoding the LIM protein CRP2: a developmental profile. J Histochem Cytochem (2002) 0.82
Biochemical and transcriptomic analyses of two bovine skeletal muscles in Charolais bulls divergently selected for muscle growth. Meat Sci (2005) 0.81
Integrin-β5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor β. Cell Cycle (2013) 0.80
Elevated expression of the integrin-associated protein PINCH suppresses the defects of Drosophila melanogaster muscle hypercontraction mutants. PLoS Genet (2013) 0.80
M19 modulates skeletal muscle differentiation and insulin secretion in pancreatic β-cells through modulation of respiratory chain activity. PLoS One (2012) 0.80
Prediction of chronic lung allograft dysfunction: a systems medicine challenge. Eur Respir J (2014) 0.79
Prognostic significance of PINCH signalling in human pancreatic ductal adenocarcinoma. HPB (Oxford) (2010) 0.79
A prioritization analysis of disease association by data-mining of functional annotation of human genes. Genomics (2011) 0.79
Modifications in the myogenic program induced by in vivo and in vitro aging. Gene (2005) 0.78
alpha-Actinin links LPP, but not zyxin, to cadherin-based junctions. Biochem Biophys Res Commun (2008) 0.78
Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure. Environ Health Perspect (2016) 0.78
Matching gene expression with hypometabolism after cerebral ischemia in the nonhuman primate. J Cereb Blood Flow Metab (2002) 0.77
A systems medicine clinical platform for understanding and managing non- communicable diseases. Curr Pharm Des (2014) 0.77
Alternative usage of 5' exons in the chicken nerve growth factor gene: refined characterization of a weakly expressed gene. Gene (2004) 0.77
Fem1a is a mitochondrial protein up-regulated upon ischemia-reperfusion injury. FEBS Lett (2009) 0.76
Affinity analysis of differentially expressed genes in hepatocytes expressing HCV core genotype 1b or 3a. Biosystems (2013) 0.76
Functional Annotation: extracting functional and regulatory order from microarrays. Mol Syst Biol (2005) 0.76
Characterization of tissue expression and full-length coding sequence of a novel human gene mapping at 3q12.1 and transcribed in oligodendrocytes. Gene (2002) 0.76
Reference values for vastus lateralis fiber type proportion and fiber size. J Appl Physiol (1985) (2014) 0.75
Deletion of Drosophila muscle LIM protein decreases flight muscle stiffness and power generation. Am J Physiol Cell Physiol (2011) 0.75
Sex-linked recombination variation and distribution of disease-related genes. Gene (2005) 0.75
[The diversity of aging models]. Med Sci (Paris) (2012) 0.75
Nuclear translocation of the cytoskeleton-associated protein, smALP, upon induction of skeletal muscle differentiation. Biochem Biophys Res Commun (2011) 0.75