Published in J Immunol on March 01, 2003
Anaplasma phagocytophilum utilizes multiple host evasion mechanisms to thwart NADPH oxidase-mediated killing during neutrophil infection. Infect Immun (2004) 1.52
Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family. Physiol Rev (2013) 1.35
Voltage-gated proton channels find their dream job managing the respiratory burst in phagocytes. Physiology (Bethesda) (2010) 1.22
The pH dependence of NADPH oxidase in human eosinophils. J Physiol (2005) 1.19
Negative regulation of eosinophil recruitment to the lung by the chemokine monokine induced by IFN-gamma (Mig, CXCL9). Proc Natl Acad Sci U S A (2004) 1.18
Eosinophil granule proteins: form and function. J Biol Chem (2014) 1.10
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate inhibits degranulation of human leukocytes in vitro. Am J Respir Cell Mol Biol (2006) 1.07
Mechanisms of degranulation in neutrophils. Allergy Asthma Clin Immunol (2006) 1.02
Biodegradation of single-walled carbon nanotubes by eosinophil peroxidase. Small (2013) 1.01
CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism. Blood (2005) 0.91
Regulation of inflammation by Rac2 in immune complex-mediated acute lung injury. Am J Physiol Lung Cell Mol Physiol (2009) 0.86
Sputum analysis in diagnosis and management of obstructive airway diseases. Ther Clin Risk Manag (2005) 0.85
Proton channel HVCN1 is required for effector functions of mouse eosinophils. BMC Immunol (2013) 0.83
An essential role for Rab27a GTPase in eosinophil exocytosis. J Leukoc Biol (2013) 0.82
Nutritional supplements and plasma antioxidants in childhood asthma. Wien Klin Wochenschr (2013) 0.81
The tripeptide feG regulates the production of intracellular reactive oxygen species by neutrophils. J Inflamm (Lond) (2006) 0.77
Reactive Oxygen Species as Additional Determinants for Cytotoxicity of Clostridium difficile Toxins A and B. Toxins (Basel) (2016) 0.77
Agonist activation of f-actin-mediated eosinophil shape change and mediator release is dependent on Rac2. Int Arch Allergy Immunol (2011) 0.76
Regulation of immune responses by proton channels. Immunology (2014) 0.76
Chloride Channel 3 Channels in the Activation and Migration of Human Blood Eosinophils in Allergic Asthma. Am J Respir Cell Mol Biol (2015) 0.76
The intimate and controversial relationship between voltage-gated proton channels and the phagocyte NADPH oxidase. Immunol Rev (2016) 0.75
Dietary supplementation with two Lamiaceae herbs-(oregano and sage) modulates innate immunity parameters in Lumbricus terrestris. Pharmacognosy Res (2013) 0.75
Eosinophils in Autoimmune Diseases. Front Immunol (2017) 0.75
Contemporary management of chronic obstructive pulmonary disease: scientific review. JAMA (2003) 4.88
Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? The potential role of systemic inflammation in chronic obstructive pulmonary disease. Circulation (2003) 4.63
The relationship between reduced lung function and cardiovascular mortality: a population-based study and a systematic review of the literature. Chest (2005) 4.41
Eosinophils: biological properties and role in health and disease. Clin Exp Allergy (2008) 3.92
Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2004) 3.88
The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2008) 3.85
Prevalence of pulmonary embolism in acute exacerbations of COPD: a systematic review and metaanalysis. Chest (2008) 2.93
Club cell protein 16 and disease progression in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 2.82
Obesity is a risk factor for dyspnea but not for airflow obstruction. Arch Intern Med (2002) 2.36
Chronic obstructive pulmonary disease as a risk factor for cardiovascular morbidity and mortality. Proc Am Thorac Soc (2005) 2.17
Inhaled corticosteroids for chronic obstructive pulmonary disease. BMJ (2012) 2.04
The growing burden of chronic obstructive pulmonary disease and lung cancer in women: examining sex differences in cigarette smoke metabolism. Am J Respir Crit Care Med (2007) 2.04
The interactions between cigarette smoking and reduced lung function on systemic inflammation. Chest (2005) 1.91
The impact of follow-up physician visits on emergency readmissions for patients with asthma and chronic obstructive pulmonary disease: a population-based study. Am J Med (2002) 1.90
Pharmacological management to reduce exacerbations in adults with asthma: a systematic review and meta-analysis. JAMA (2004) 1.84
Connective tissue-activating peptide III: a novel blood biomarker for early lung cancer detection. J Clin Oncol (2009) 1.68
Low-dose inhaled corticosteroid therapy and risk of emergency department visits for asthma. Arch Intern Med (2002) 1.67
Arterial carbon dioxide tension on admission as a marker of in-hospital mortality in community-acquired pneumonia. Am J Med (2005) 1.64
Anaplasma phagocytophilum utilizes multiple host evasion mechanisms to thwart NADPH oxidase-mediated killing during neutrophil infection. Infect Immun (2004) 1.52
The complex relationship of serum adiponectin to COPD outcomes COPD and adiponectin. Chest (2012) 1.50
Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis. Respir Res (2006) 1.44
Cutting edge: human eosinophils regulate T cell subset selection through indoleamine 2,3-dioxygenase. J Immunol (2004) 1.42
Do chronic inhaled steroids alone or in combination with a bronchodilator prolong life in chronic obstructive pulmonary disease patients? Curr Opin Pulm Med (2007) 1.41
Inflammatory cells in asthma: mechanisms and implications for therapy. J Allergy Clin Immunol (2003) 1.41
Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction. Am J Physiol Lung Cell Mol Physiol (2008) 1.38
The risk of osteoporosis in Caucasian men and women with obstructive airways disease. Am J Med (2003) 1.36
Distribution of nitric oxide synthase in normal and cirrhotic human liver. Proc Natl Acad Sci U S A (2002) 1.33
Understanding exocytosis in immune and inflammatory cells: the molecular basis of mediator secretion. J Allergy Clin Immunol (2003) 1.33
The airway epithelium: more than just a structural barrier. Ther Adv Respir Dis (2011) 1.30
Eosinophil granules function extracellularly as receptor-mediated secretory organelles. Proc Natl Acad Sci U S A (2008) 1.30
Rac2 is critical for neutrophil primary granule exocytosis. Blood (2004) 1.26
Can universal access to health care eliminate health inequities between children of poor and nonpoor families?: A case study of childhood asthma in Alberta. Chest (2003) 1.23
Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2011) 1.23
Human eosinophils express and release IL-13 following CD28-dependent activation. J Leukoc Biol (2002) 1.21
Asthma and COPD among aboriginals in Alberta, Canada. Chest (2002) 1.17
Human versus mouse eosinophils: "that which we call an eosinophil, by any other name would stain as red". J Allergy Clin Immunol (2012) 1.16
The role of female hormones on lung function in chronic lung diseases. BMC Womens Health (2011) 1.16
The relationship between telomere length and mortality in chronic obstructive pulmonary disease (COPD). PLoS One (2012) 1.12
Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD). J Allergy Clin Immunol (2012) 1.12
The development of a sensitive and specific ELISA for mouse eosinophil peroxidase: assessment of eosinophil degranulation ex vivo and in models of human disease. J Immunol Methods (2011) 1.12
Management of asthma among community-based primary care physicians. J Asthma (2005) 1.12
Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing Cre recombinase exclusively in eosinophils. J Leukoc Biol (2013) 1.11
Progression of airway dysplasia and C-reactive protein in smokers at high risk of lung cancer. Am J Respir Crit Care Med (2005) 1.09
Chronic obstructive pulmonary disease: a novel risk factor for cardiovascular disease. Can J Physiol Pharmacol (2005) 1.08
The induction of eosinophil peroxidase release: improved methods of measurement and stimulation. J Immunol Methods (2004) 1.07
Systemic inflammation and mortality in chronic obstructive pulmonary disease. Can J Physiol Pharmacol (2007) 1.05
Translocation of the tetraspanin CD63 in association with human eosinophil mediator release. Blood (2002) 1.04
Effects of increased primary care access on process of care and health outcomes among patients with asthma who frequent emergency departments. Am J Med (2004) 1.01
The relationship between birth weight and childhood asthma: a population-based cohort study. Arch Pediatr Adolesc Med (2004) 1.01
Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor. J Immunol (2010) 1.01
Effects of inhaled corticosteroids on sputum cell counts in stable chronic obstructive pulmonary disease: a systematic review and a meta-analysis. BMC Pulm Med (2005) 1.01
Interleukin-6: a red herring or a real catch in COPD? Chest (2008) 1.00
Proteinase-activated receptor (PAR)-1 and -2 agonists induce mediator release from mast cells by pathways distinct from PAR-1 and PAR-2. J Pharmacol Exp Ther (2002) 0.99
Metabolomic profiling of asthma: diagnostic utility of urine nuclear magnetic resonance spectroscopy. J Allergy Clin Immunol (2011) 0.98
Virus-induced eosinophil mediator release requires antigen-presenting and CD4+ T cells. J Allergy Clin Immunol (2008) 0.98
Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase. J Immunol (2002) 0.98
Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line. Biochem Biophys Res Commun (2007) 0.97
Telomere length and chronic obstructive pulmonary disease: evidence of accelerated aging. J Am Geriatr Soc (2009) 0.95
Differential expression of spleen tyrosine kinase Syk isoforms in tissues: Effects of the microbial flora. Histochem Cell Biol (2006) 0.95
Eosinophils in human oral squamous carcinoma; role of prostaglandin D2. J Inflamm (Lond) (2013) 0.94
Sex-related differences in serum cotinine concentrations in daily cigarette smokers. Nicotine Tob Res (2008) 0.93
Surfactant protein D: a lung specific biomarker in COPD? Ther Adv Respir Dis (2008) 0.93
Epidemic of lung cancer in patients with HIV infection. Chest (2013) 0.92
Expression of eosinophil target SNAREs as potential cognate receptors for vesicle-associated membrane protein-2 in exocytosis. J Allergy Clin Immunol (2002) 0.92
What's new in asthma pathophysiology and immunopathology? Expert Rev Respir Med (2010) 0.92
Immunodetection of occult eosinophils in lung tissue biopsies may help predict survival in acute lung injury. Respir Res (2011) 0.92
The eosinophil as a therapeutic target in asthma: beginning of the end, or end of the beginning? Curr Opin Pharmacol (2003) 0.91
The determinants of poor respiratory health status in adults living with human immunodeficiency virus infection. AIDS Patient Care STDS (2014) 0.90
Impact of cancers and cardiovascular diseases in chronic obstructive pulmonary disease. Curr Opin Pulm Med (2008) 0.90
Effects of nocturnal noninvasive mechanical ventilation on heart rate variability of patients with advanced COPD. Chest (2007) 0.90
Histological microstructure of the claws of the African clawed frog, Xenopus laevis (Anura: Pipidae): implications for the evolution of claws in tetrapods. J Exp Zool B Mol Dev Evol (2007) 0.89
Metabolomic biomarkers in a model of asthma exacerbation: urine nuclear magnetic resonance. Am J Respir Crit Care Med (2008) 0.89
Endotoxin-induced translocation of interleukin-6 from lungs to the systemic circulation. Innate Immun (2009) 0.88
Circulating surfactant protein-D and the risk of cardiovascular morbidity and mortality. Eur Heart J (2011) 0.87
Changes in thymic regulatory T-cell maturation from birth to puberty: differences in atopic children. J Allergy Clin Immunol (2011) 0.87
Thymic indoleamine 2,3-dioxygenase-positive eosinophils in young children: potential role in maturation of the naive immune system. Am J Pathol (2009) 0.86
Corticosteroids and adrenoceptor agonists: the compliments for combination therapy in chronic airways diseases. Eur J Pharmacol (2006) 0.86
Regulation of inflammation by Rac2 in immune complex-mediated acute lung injury. Am J Physiol Lung Cell Mol Physiol (2009) 0.86
Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs (2006) 0.85
Can inhaled fluticasone alone or in combination with salmeterol reduce systemic inflammation in chronic obstructive pulmonary disease? Study protocol for a randomized controlled trial [NCT00120978]. BMC Pulm Med (2006) 0.85
Nitric oxide activates ATP-dependent K+ channels in human eosinophils. J Leukoc Biol (2002) 0.85
The effect of cationic charge on release of eosinophil mediators. J Allergy Clin Immunol (2008) 0.84
Pharmacotherapy for mortality reduction in chronic obstructive pulmonary disease. Proc Am Thorac Soc (2006) 0.83
The relationship of systemic inflammation to prior hospitalization in adult patients with cystic fibrosis. BMC Pulm Med (2012) 0.83
Neutrophil primary granule release and maximal superoxide generation depend on Rac2 in a common signalling pathway. Can J Physiol Pharmacol (2005) 0.83
The costs of implementing the 1999 Canadian Asthma Consensus Guidelines recommendation of asthma education and spirometry for the family physician. Can Respir J (2004) 0.83
An essential role for Rab27a GTPase in eosinophil exocytosis. J Leukoc Biol (2013) 0.82
Thinning bone and inhaled corticosteroid in COPD: what to do until there is definitive proof? Chest (2009) 0.82
Biomarkers in COPD: are we there yet? Chest (2008) 0.82
Dentin matrix protein-1 activates dental pulp fibroblasts. J Endod (2011) 0.82
Surfactant protein D and bronchial dysplasia in smokers at high risk of lung cancer. Chest (2008) 0.82
The relation of serum myeloperoxidase to disease progression and mortality in patients with chronic obstructive pulmonary disease (COPD). PLoS One (2013) 0.81
Systemic consequences of COPD. Ther Adv Respir Dis (2007) 0.81
A curious case of beta-blockers in chronic obstructive pulmonary disease. Arch Intern Med (2010) 0.80
Cyclin-dependent kinase 5 regulates degranulation in human eosinophils. Immunology (2015) 0.80
Mechanisms of eosinophil recruitment and activation. Curr Allergy Asthma Rep (2002) 0.79
Interleukin-12 inhibits eosinophil degranulation and migration but does not promote eosinophil apoptosis. Int Arch Allergy Immunol (2006) 0.79
Eosinophil function in allergic inflammation: from bone marrow to tissue response. Curr Allergy Asthma Rep (2004) 0.79
Extracellular 14-3-3 from human lung epithelial cells enhances MMP-1 expression. Mol Cell Biochem (2011) 0.79