Published in Bioessays on March 01, 2003
Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis. Genome Dyn Stab (2008) 2.03
The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold. Proc Natl Acad Sci U S A (2004) 1.93
Three RNA cells for ribosomal lineages and three DNA viruses to replicate their genomes: a hypothesis for the origin of cellular domain. Proc Natl Acad Sci U S A (2006) 1.90
Nanoarchaea: representatives of a novel archaeal phylum or a fast-evolving euryarchaeal lineage related to Thermococcales? Genome Biol (2005) 1.60
Phylogenetic evidence for extensive lateral acquisition of cellular genes by Nucleocytoplasmic large DNA viruses. BMC Evol Biol (2008) 1.51
Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase. PLoS One (2010) 1.35
Cellular strategies for regulating DNA supercoiling: a single-molecule perspective. Cell (2010) 1.25
Phylogenomics of DNA topoisomerases: their origin and putative roles in the emergence of modern organisms. Nucleic Acids Res (2009) 1.25
BIN4, a novel component of the plant DNA topoisomerase VI complex, is required for endoreduplication in Arabidopsis. Plant Cell (2007) 1.23
RHL1 is an essential component of the plant DNA topoisomerase VI complex and is required for ploidy-dependent cell growth. Proc Natl Acad Sci U S A (2005) 1.17
Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target. PLoS One (2007) 1.17
A DNA topoisomerase IB in Thaumarchaeota testifies for the presence of this enzyme in the last common ancestor of Archaea and Eucarya. Biol Direct (2008) 1.13
The catalytically active tyrosine residues of both SPO11-1 and SPO11-2 are required for meiotic double-strand break induction in Arabidopsis. Plant Cell (2007) 1.08
The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks. Nucleic Acids Res (2011) 1.07
Inhibition of archaeal growth and DNA topoisomerase VI activities by the Hsp90 inhibitor radicicol. Nucleic Acids Res (2005) 1.03
The key DNA-binding residues in the C-terminal domain of Mycobacterium tuberculosis DNA gyrase A subunit (GyrA). Nucleic Acids Res (2006) 1.03
AromaDeg, a novel database for phylogenomics of aerobic bacterial degradation of aromatics. Database (Oxford) (2014) 1.02
Discovery of novel DNA gyrase inhibitors by high-throughput virtual screening. Antimicrob Agents Chemother (2007) 1.02
Meiotic association between Spo11 regulated by Rec102, Rec104 and Rec114. Nucleic Acids Res (2007) 0.99
Genomic context analysis in Archaea suggests previously unrecognized links between DNA replication and translation. Genome Biol (2008) 0.94
Gyrase B inhibitor impairs HIV-1 replication by targeting Hsp90 and the capsid protein. J Biol Chem (2010) 0.94
SUMO modification of DNA topoisomerase II: trying to get a CENse of it all. DNA Repair (Amst) (2009) 0.89
Structural basis for topoisomerase VI inhibition by the anti-Hsp90 drug radicicol. Nucleic Acids Res (2006) 0.88
DNA topoisomerase III from the hyperthermophilic archaeon Sulfolobus solfataricus with specific DNA cleavage activity. J Bacteriol (2003) 0.86
Meiotic recombination protein Rec12: functional conservation, crossover homeostasis and early crossover/non-crossover decision. Nucleic Acids Res (2010) 0.84
Distinct regions of the Escherichia coli ParC C-terminal domain are required for substrate discrimination by topoisomerase IV. J Mol Biol (2013) 0.83
Comparison of DNA decatenation by Escherichia coli topoisomerase IV and topoisomerase III: implications for non-equilibrium topology simplification. Nucleic Acids Res (2013) 0.83
Effects of ciprofloxacin-containing antimicrobial scaffolds on dental pulp stem cell viability-In vitro studies. Arch Oral Biol (2015) 0.81
Phylogenetic molecular function annotation. J Phys Conf Ser (2009) 0.81
Purification, folding, and characterization of Rec12 (Spo11) meiotic recombinase of fission yeast. Protein Expr Purif (2004) 0.79
DNA topoisomerase VIII: a novel subfamily of type IIB topoisomerases encoded by free or integrated plasmids in Archaea and Bacteria. Nucleic Acids Res (2014) 0.78
Binding of two DNA molecules by type II topoisomerases for decatenation. Nucleic Acids Res (2012) 0.77
Characterization of the DNA gyrase from the thermoacidophilic archaeon Thermoplasma acidophilum. J Bacteriol (2005) 0.75
Over-expression of Topoisomerase II Enhances Salt Stress Tolerance in Tobacco. Front Plant Sci (2016) 0.75
Topoisomerase 2 is dispensable for the replication and segregation of small yeast artificial chromosomes (YACs). PLoS One (2014) 0.75
Mesophilic Crenarchaeota: proposal for a third archaeal phylum, the Thaumarchaeota. Nat Rev Microbiol (2008) 5.31
The virophage as a unique parasite of the giant mimivirus. Nature (2008) 4.09
An alternative flavin-dependent mechanism for thymidylate synthesis. Science (2002) 3.82
Redefining viruses: lessons from Mimivirus. Nat Rev Microbiol (2008) 3.27
Insertion sequences in prokaryotic genomes. Curr Opin Microbiol (2006) 2.78
An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi. Mol Microbiol (2003) 2.75
Viruses of the Archaea: a unifying view. Nat Rev Microbiol (2006) 2.61
Archaeal phylogeny based on ribosomal proteins. Mol Biol Evol (2002) 1.92
Evolution of DNA polymerase families: evidences for multiple gene exchange between cellular and viral proteins. J Mol Evol (2002) 1.91
Archaeal phylogeny based on proteins of the transcription and translation machineries: tackling the Methanopyrus kandleri paradox. Genome Biol (2004) 1.71
Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea. Genome Biol (2009) 1.69
Phylogeny and evolution of the Archaea: one hundred genomes later. Curr Opin Microbiol (2011) 1.68
The struggle for life of the genome's selfish architects. Biol Direct (2011) 1.64
The archeoviruses. FEMS Microbiol Rev (2011) 1.62
Nanoarchaea: representatives of a novel archaeal phylum or a fast-evolving euryarchaeal lineage related to Thermococcales? Genome Biol (2005) 1.60
Pyrococcus genome comparison evidences chromosome shuffling-driven evolution. Nucleic Acids Res (2002) 1.58
A unique virus release mechanism in the Archaea. Proc Natl Acad Sci U S A (2009) 1.47
The role played by viruses in the evolution of their hosts: a view based on informational protein phylogenies. Res Microbiol (2003) 1.43
An emerging phylogenetic core of Archaea: phylogenies of transcription and translation machineries converge following addition of new genome sequences. BMC Evol Biol (2005) 1.42
A hidden reservoir of integrative elements is the major source of recently acquired foreign genes and ORFans in archaeal and bacterial genomes. Genome Biol (2009) 1.41
The origin of eukaryotes and their relationship with the Archaea: are we at a phylogenomic impasse? Nat Rev Microbiol (2010) 1.40
Identification of short 'eukaryotic' Okazaki fragments synthesized from a prokaryotic replication origin. EMBO Rep (2003) 1.39
An archaeal orthologue of the universal protein Kae1 is an iron metalloprotein which exhibits atypical DNA-binding properties and apurinic-endonuclease activity in vitro. Nucleic Acids Res (2007) 1.36
Four newly isolated fuselloviruses from extreme geothermal environments reveal unusual morphologies and a possible interviral recombination mechanism. Environ Microbiol (2009) 1.27
Construction of a shuttle vector for, and spheroplast transformation of, the hyperthermophilic archaeon Pyrococcus abyssi. Appl Environ Microbiol (2002) 1.26
NurA, a novel 5'-3' nuclease gene linked to rad50 and mre11 homologs of thermophilic Archaea. EMBO Rep (2002) 1.25
Casposons: a new superfamily of self-synthesizing DNA transposons at the origin of prokaryotic CRISPR-Cas immunity. BMC Biol (2014) 1.25
Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex. EMBO J (2008) 1.21
Widespread distribution of archaeal reverse gyrase in thermophilic bacteria suggests a complex history of vertical inheritance and lateral gene transfers. Archaea (2007) 1.19
Microviridae goes temperate: microvirus-related proviruses reside in the genomes of Bacteroidetes. PLoS One (2011) 1.18
Qri7/OSGEPL, the mitochondrial version of the universal Kae1/YgjD protein, is essential for mitochondrial genome maintenance. Nucleic Acids Res (2009) 1.17
On the last common ancestor and early evolution of eukaryotes: reconstructing the history of mitochondrial ribosomes. Res Microbiol (2010) 1.16
DNA bending, compaction and negative supercoiling by the architectural protein Sso7d of Sulfolobus solfataricus. Nucleic Acids Res (2002) 1.14
The Sulfolobus rod-shaped virus 2 encodes a prominent structural component of the unique virion release system in Archaea. Virology (2010) 1.13
A DNA topoisomerase IB in Thaumarchaeota testifies for the presence of this enzyme in the last common ancestor of Archaea and Eucarya. Biol Direct (2008) 1.13
Diversity of virus-host systems in hypersaline Lake Retba, Senegal. Environ Microbiol (2010) 1.12
Virus-like vesicles and extracellular DNA produced by hyperthermophilic archaea of the order Thermococcales. Res Microbiol (2008) 1.12
Comparative analysis of the mosaic genomes of tailed archaeal viruses and proviruses suggests common themes for virion architecture and assembly with tailed viruses of bacteria. J Mol Biol (2010) 1.12
The Mre11 protein interacts with both Rad50 and the HerA bipolar helicase and is recruited to DNA following gamma irradiation in the archaeon Sulfolobus acidocaldarius. BMC Mol Biol (2008) 1.10
Thermococcus gammatolerans sp. nov., a hyperthermophilic archaeon from a deep-sea hydrothermal vent that resists ionizing radiation. Int J Syst Evol Microbiol (2003) 1.07
The evolutionary history of archaeal MCM helicases: a case study of vertical evolution combined with hitchhiking of mobile genetic elements. Mol Biol Evol (2010) 1.07
Simple and elegant design of a virion egress structure in Archaea. Proc Natl Acad Sci U S A (2011) 1.04
Viral proteins functioning in organelles: a cryptic origin? Trends Microbiol (2005) 1.04
Two novel families of plasmids from hyperthermophilic archaea encoding new families of replication proteins. Nucleic Acids Res (2010) 1.04
Massive activation of archaeal defense genes during viral infection. J Virol (2013) 1.03
Plasmids, viruses and virus-like membrane vesicles from Thermococcales. Biochem Soc Trans (2011) 1.03
Global phylogenomic analysis disentangles the complex evolutionary history of DNA replication in archaea. Genome Biol Evol (2014) 1.03
In vitro biosynthesis of a universal t6A tRNA modification in Archaea and Eukarya. Nucleic Acids Res (2012) 1.03
Chimeric viruses blur the borders between the major groups of eukaryotic single-stranded DNA viruses. Nat Commun (2013) 1.02
Genomics and genetics of Sulfolobus islandicus LAL14/1, a model hyperthermophilic archaeon. Open Biol (2013) 1.02
Identification, purification, and characterization of an eukaryotic-like phosphopantetheine adenylyltransferase (coenzyme A biosynthetic pathway) in the hyperthermophilic archaeon Pyrococcus abyssi. J Biol Chem (2003) 1.01
Insights into dynamics of mobile genetic elements in hyperthermophilic environments from five new Thermococcus plasmids. PLoS One (2013) 1.01
Evidence for a Xer/dif system for chromosome resolution in archaea. PLoS Genet (2010) 1.01
Archaeal virus with exceptional virion architecture and the largest single-stranded DNA genome. Proc Natl Acad Sci U S A (2012) 1.01
Functional assignment of KEOPS/EKC complex subunits in the biosynthesis of the universal t6A tRNA modification. Nucleic Acids Res (2013) 0.99
Unification of the globally distributed spindle-shaped viruses of the Archaea. J Virol (2013) 0.99
Hyperthermophilic archaea produce membrane vesicles that can transfer DNA. Environ Microbiol Rep (2012) 0.98
Postcards from the edge: structural genomics of archaeal viruses. Adv Virus Res (2012) 0.98
Crenarchaeal CdvA forms double-helical filaments containing DNA and interacts with ESCRT-III-like CdvB. PLoS One (2011) 0.98
Molecular diversity of new Thermococcales isolates from a single area of hydrothermal deep-sea vents as revealed by randomly amplified polymorphic DNA fingerprinting and 16S rRNA gene sequence analysis. Appl Environ Microbiol (2004) 0.97
The rolling-circle plasmid pTN1 from the hyperthermophilic archaeon Thermococcus nautilus. Mol Microbiol (2007) 0.97
Structural insights into a new homodimeric self-activated GTPase family. EMBO Rep (2007) 0.97
Acidianus filamentous virus 1 coat proteins display a helical fold spanning the filamentous archaeal viruses lineage. Proc Natl Acad Sci U S A (2009) 0.97
Assessment of viral community functional potential from viral metagenomes may be hampered by contamination with cellular sequences. Open Biol (2013) 0.96
The universal Kae1 protein and the associated Bud32 kinase (PRPK), a mysterious protein couple probably essential for genome maintenance in Archaea and Eukarya. Biochem Soc Trans (2009) 0.95
The legacy of Carl Woese and Wolfram Zillig: from phylogeny to landmark discoveries. Nat Rev Microbiol (2013) 0.94
Crystal structure of AFV3-109, a highly conserved protein from crenarchaeal viruses. Virol J (2007) 0.94
Genomic context analysis in Archaea suggests previously unrecognized links between DNA replication and translation. Genome Biol (2008) 0.94
Genomewide and biochemical analyses of DNA-binding activity of Cdc6/Orc1 and Mcm proteins in Pyrococcus sp. Nucleic Acids Res (2007) 0.94
Genetic analysis of DNA repair in the hyperthermophilic archaeon, Thermococcus kodakaraensis. Genes Genet Syst (2010) 0.94
First insights into the entry process of hyperthermophilic archaeal viruses. J Virol (2013) 0.93
A highly divergent archaeo-eukaryotic primase from the Thermococcus nautilus plasmid, pTN2. Nucleic Acids Res (2014) 0.92
Dark matter in archaeal genomes: a rich source of novel mobile elements, defense systems and secretory complexes. Extremophiles (2014) 0.92
Novel archaeal plasmid pAH1 and its interactions with the lipothrixvirus AFV1. Mol Microbiol (2008) 0.90
Evolution of the Australian lungfish (Neoceratodus forsteri) genome: a major role for CR1 and L2 LINE elements. Mol Biol Evol (2012) 0.90
Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms. Structure (2008) 0.89
Physiological responses of the hyperthermophilic archaeon "Pyrococcus abyssi" to DNA damage caused by ionizing radiation. J Bacteriol (2003) 0.89
Automatic classification within families of transposable elements: application to the mariner Family. Gene (2009) 0.88
Extracellular membrane vesicles harbouring viral genomes. Environ Microbiol (2013) 0.87
Pharmacokinetics and Toxicity in Rats and Monkeys of coDbait: A Therapeutic Double-stranded DNA Oligonucleotide Conjugated to Cholesterol. Mol Ther Nucleic Acids (2012) 0.87
A thermodynamic model of the cooperative interaction between the archaeal transcription factor Ss-LrpB and its tripartite operator DNA. Gene (2013) 0.86
Viruses in acidic geothermal environments of the Kamchatka Peninsula. Res Microbiol (2008) 0.86
Membrane vesicles, nanopods and/or nanotubes produced by hyperthermophilic archaea of the genus Thermococcus. Biochem Soc Trans (2013) 0.85
A thaumarchaeal provirus testifies for an ancient association of tailed viruses with archaea. Biochem Soc Trans (2011) 0.85
Self-assembly of the general membrane-remodeling protein PVAP into sevenfold virus-associated pyramids. Proc Natl Acad Sci U S A (2014) 0.84
Inhibition of DNA damage repair by artificial activation of PARP with siDNA. Nucleic Acids Res (2013) 0.84
When DNA replication and protein synthesis come together. Trends Biochem Sci (2009) 0.84
Thermococcus nautili sp. nov., a hyperthermophilic archaeon isolated from a hydrothermal deep-sea vent. Int J Syst Evol Microbiol (2014) 0.84
Thermococcus marinus sp. nov. and Thermococcus radiotolerans sp. nov., two hyperthermophilic archaea from deep-sea hydrothermal vents that resist ionizing radiation. Extremophiles (2004) 0.84
Synthesis and biological evaluation of acridine derivatives as antimalarial agents. ChemMedChem (2012) 0.83
The origin of modern terrestrial life. HFSP J (2007) 0.83
The HSP90 and DNA topoisomerase VI inhibitor radicicol also inhibits human type II DNA topoisomerase. Biochem Pharmacol (2006) 0.82
RNA at 92 °C: the non-coding transcriptome of the hyperthermophilic archaeon Pyrococcus abyssi. RNA Biol (2013) 0.82
Living side by side with a virus: characterization of two novel plasmids from Thermococcus prieurii, a host for the spindle-shaped virus TPV1. Appl Environ Microbiol (2013) 0.81
Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes. Biochem J (2013) 0.80
The SF1 helicase encoded by the archaeal plasmid pTN2 of Thermococcus nautili. Extremophiles (2014) 0.80
Genome Sequence of a Hyperthermophilic Archaeon, Thermococcus nautili 30-1, That Produces Viral Vesicles. Genome Announc (2014) 0.78
[T4-type bacteriophages: ubiquitous components of the "dark matter" of the biosphere]. Med Sci (Paris) (2006) 0.78