Published in Proc Natl Acad Sci U S A on February 21, 2003
The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPase. Microbiol Mol Biol Rev (2006) 2.79
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Crystal structure of a central stalk subunit C and reversible association/dissociation of vacuole-type ATPase. Proc Natl Acad Sci U S A (2003) 1.66
Regulation and isoform function of the V-ATPases. Biochemistry (2010) 1.57
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Dodecamer rotor ring defines H+/ATP ratio for ATP synthesis of prokaryotic V-ATPase from Thermus thermophilus. Proc Natl Acad Sci U S A (2007) 1.33
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Rotation scheme of V1-motor is different from that of F1-motor. Proc Natl Acad Sci U S A (2005) 1.28
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Structural and functional separation of the N- and C-terminal domains of the yeast V-ATPase subunit H. J Biol Chem (2005) 1.09
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Assembly and regulation of the yeast vacuolar H+-ATPase. J Bioenerg Biomembr (2003) 1.07
Definition of membrane topology and identification of residues important for transport in subunit a of the vacuolar ATPase. J Biol Chem (2011) 1.03
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Function and subunit interactions of the N-terminal domain of subunit a (Vph1p) of the yeast V-ATPase. J Biol Chem (2008) 0.97
Basic properties of rotary dynamics of the molecular motor Enterococcus hirae V1-ATPase. J Biol Chem (2013) 0.97
Voa1p functions in V-ATPase assembly in the yeast endoplasmic reticulum. Mol Biol Cell (2008) 0.96
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The insect plasma membrane H+ V-ATPase: intra-, inter-, and supramolecular aspects. J Bioenerg Biomembr (2003) 0.87
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Regulated assembly of vacuolar ATPase is increased during cluster disruption-induced maturation of dendritic cells through a phosphatidylinositol 3-kinase/mTOR-dependent pathway. J Biol Chem (2013) 0.87
Seventeen a-subunit isoforms of paramecium V-ATPase provide high specialization in localization and function. Mol Biol Cell (2005) 0.86
The tether connecting cytosolic (N terminus) and membrane (C terminus) domains of yeast V-ATPase subunit a (Vph1) is required for assembly of V0 subunit d. J Biol Chem (2009) 0.86
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F1 rotary motor of ATP synthase is driven by the torsionally-asymmetric drive shaft. Sci Rep (2016) 0.84
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Flexibility within the rotor and stators of the vacuolar H+-ATPase. PLoS One (2013) 0.83
Torque generation of Enterococcus hirae V-ATPase. J Biol Chem (2014) 0.82
Ligand-dependent structural changes in the V(1) ATPase from Manduca sexta. J Bioenerg Biomembr (2004) 0.82
PA1b inhibitor binding to subunits c and e of the vacuolar ATPase reveals its insecticidal mechanism. J Biol Chem (2014) 0.82
ATP synthase: from single molecule to human bioenergetics. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.82
Mechanism of inhibition of the V-type molecular motor by tributyltin chloride. Biophys J (2009) 0.81
Single-molecule analysis of inhibitory pausing states of V1-ATPase. J Biol Chem (2012) 0.81
The V-ATPase in Paramecium: functional specialization by multiple gene isoforms. Pflugers Arch (2008) 0.80
A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles. Nat Commun (2015) 0.80
Biological Nanomotors with a Revolution, Linear, or Rotation Motion Mechanism. Microbiol Mol Biol Rev (2016) 0.80
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F-subunit reinforces torque generation in V-ATPase. Eur Biophys J (2014) 0.80
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Molecular basis of ADP inhibition of vacuolar (V)-type ATPase/synthase. J Biol Chem (2013) 0.79
Structure and function of the vacuolar H+-ATPase: moving from low-resolution models to high-resolution structures. J Bioenerg Biomembr (2003) 0.79
Interaction of the Thermoplasma acidophilum A1A0-ATP synthase peripheral stalk with the catalytic domain. FEBS Lett (2009) 0.78
The d subunit plays a central role in human vacuolar H(+)-ATPases. J Bioenerg Biomembr (2008) 0.78
Close-up and genomic views of the yeast vacuolar H+-ATPase. J Bioenerg Biomembr (2005) 0.78
Rotation of artificial rotor axles in rotary molecular motors. Proc Natl Acad Sci U S A (2016) 0.77
Power Stroke Angular Velocity Profiles of Archaeal A-ATP Synthase Versus Thermophilic and Mesophilic F-ATP Synthase Molecular Motors. J Biol Chem (2016) 0.76
Vma8p-GFP fusions can be functionally incorporated into V-ATPase, suggesting structural flexibility at the top of V1. Int J Mol Sci (2011) 0.75
Investigation of endosome and lysosome biology by ultra pH-sensitive nanoprobes. Adv Drug Deliv Rev (2016) 0.75
Purification, crystallization and preliminary crystallographic analysis of the vacuole-type ATPase subunit E from Pyrococcus horikoshii OT3. Acta Crystallogr Sect F Struct Biol Cryst Commun (2004) 0.75
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Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase. Nature (2001) 5.63
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V-Type H+-ATPase/synthase from a thermophilic eubacterium, Thermus thermophilus. Subunit structure and operon. J Biol Chem (2000) 1.22
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Isolation of prokaryotic V0V1-ATPase from a thermophilic eubacterium Thermus thermophilus. J Biol Chem (1994) 0.97
Hysteretic inhibition of the bovine heart mitochondrial F1-ATPase is due to saturation of noncatalytic sites with ADP which blocks activation of the enzyme by ATP. J Biol Chem (1994) 0.91
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An expanded palette of genetically encoded Ca²⁺ indicators. Science (2011) 5.05
Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation. Cell (2007) 4.09
Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators. Proc Natl Acad Sci U S A (2009) 3.57
Mechanically driven ATP synthesis by F1-ATPase. Nature (2004) 3.45
Chemomechanical coupling in F1-ATPase revealed by simultaneous observation of nucleotide kinetics and rotation. Nat Struct Mol Biol (2004) 3.23
The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. Cell (2003) 2.89
Catalysis and rotation of F1 motor: cleavage of ATP at the catalytic site occurs in 1 ms before 40 degree substep rotation. Proc Natl Acad Sci U S A (2003) 2.65
High-speed atomic force microscopy reveals rotary catalysis of rotorless F₁-ATPase. Science (2011) 2.56
Highly coupled ATP synthesis by F1-ATPase single molecules. Nature (2005) 2.32
Prevalence of genital mycoplasmas and ureaplasmas in men younger than 40 years-of-age with acute epididymitis. Int J Urol (2011) 2.08
beta-Helix is a likely core structure of yeast prion Sup35 amyloid fibers. Biochem Biophys Res Commun (2004) 1.83
Escherichia coli phage-shock protein A (PspA) binds to membrane phospholipids and repairs proton leakage of the damaged membranes. Mol Microbiol (2007) 1.74
Crystal structure of a central stalk subunit C and reversible association/dissociation of vacuole-type ATPase. Proc Natl Acad Sci U S A (2003) 1.66
Phosphate release in F1-ATPase catalytic cycle follows ADP release. Nat Chem Biol (2010) 1.65
The role of Mycoplasma genitalium and Ureaplasma urealyticum biovar 2 in postgonococcal urethritis. Clin Infect Dis (2007) 1.64
Microfabricated arrays of femtoliter chambers allow single molecule enzymology. Nat Biotechnol (2005) 1.63
Cooperative three-step motions in catalytic subunits of F(1)-ATPase correlate with 80 degrees and 40 degrees substep rotations. Nat Struct Mol Biol (2008) 1.63
Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75. FEBS Lett (2002) 1.63
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F1-ATPase rotates by an asymmetric, sequential mechanism using all three catalytic subunits. Nat Struct Mol Biol (2007) 1.53
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Thermophilic ATP synthase has a decamer c-ring: indication of noninteger 10:3 H+/ATP ratio and permissive elastic coupling. Proc Natl Acad Sci U S A (2004) 1.48
Structure of the whole cytosolic region of ATP-dependent protease FtsH. Mol Cell (2006) 1.46
ATP-driven stepwise rotation of FoF1-ATP synthase. Proc Natl Acad Sci U S A (2005) 1.43
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One rotary mechanism for F1-ATPase over ATP concentrations from millimolar down to nanomolar. Biophys J (2004) 1.40
Axle-less F1-ATPase rotates in the correct direction. Science (2008) 1.36
GroEL mediates protein folding with a two successive timer mechanism. Mol Cell (2004) 1.36
Subunit arrangement in V-ATPase from Thermus thermophilus. J Biol Chem (2003) 1.36
F0F1-ATPase/synthase is geared to the synthesis mode by conformational rearrangement of epsilon subunit in response to proton motive force and ADP/ATP balance. J Biol Chem (2003) 1.36
Chemo-mechanical coupling in F(1)-ATPase revealed by catalytic site occupancy during catalysis. Biophys J (2010) 1.35
Convergence of cell cycle regulation and growth factor signals on GRASP65. J Biol Chem (2005) 1.35
The ATP-waiting conformation of rotating F1-ATPase revealed by single-pair fluorescence resonance energy transfer. Proc Natl Acad Sci U S A (2003) 1.34
Ca²⁺ regulation of mitochondrial ATP synthesis visualized at the single cell level. ACS Chem Biol (2011) 1.34
Hsp104 binds to yeast Sup35 prion fiber but needs other factor(s) to sever it. J Biol Chem (2004) 1.34
Dodecamer rotor ring defines H+/ATP ratio for ATP synthesis of prokaryotic V-ATPase from Thermus thermophilus. Proc Natl Acad Sci U S A (2007) 1.33
Mechanical modulation of catalytic power on F1-ATPase. Nat Chem Biol (2011) 1.33
Regulatory interplay between proton motive force, ADP, phosphate, and subunit epsilon in bacterial ATP synthase. J Biol Chem (2006) 1.32
Structures of the thermophilic F1-ATPase epsilon subunit suggesting ATP-regulated arm motion of its C-terminal domain in F1. Proc Natl Acad Sci U S A (2007) 1.30
Angiopoietin-like protein 2 is an important facilitator of inflammatory carcinogenesis and metastasis. Cancer Res (2011) 1.29
Rotation scheme of V1-motor is different from that of F1-motor. Proc Natl Acad Sci U S A (2005) 1.28
Evaluation of factors related to late recurrence--later than 10 years after the initial treatment--in primary breast cancer. Oncology (2013) 1.27
F(0) of ATP synthase is a rotary proton channel. Obligatory coupling of proton translocation with rotation of c-subunit ring. J Biol Chem (2002) 1.25
Fluctuation theorem applied to F1-ATPase. Phys Rev Lett (2010) 1.25
Correlation between the conformational states of F1-ATPase as determined from its crystal structure and single-molecule rotation. Proc Natl Acad Sci U S A (2008) 1.25
Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis. Cancer Res (2012) 1.23
Crystal structure of the native chaperonin complex from Thermus thermophilus revealed unexpected asymmetry at the cis-cavity. Structure (2004) 1.23
Structure of a central stalk subunit F of prokaryotic V-type ATPase/synthase from Thermus thermophilus. EMBO J (2005) 1.21
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BeF(x) stops the chaperonin cycle of GroEL-GroES and generates a complex with double folding chambers. J Biol Chem (2004) 1.16
Simple dark-field microscopy with nanometer spatial precision and microsecond temporal resolution. Biophys J (2010) 1.16
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The role of subunit epsilon in the catalysis and regulation of FOF1-ATP synthase. Biochim Biophys Acta (2006) 1.12
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Temperature-sensitive reaction intermediate of F1-ATPase. EMBO Rep (2007) 1.11
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Knockdown of DAPIT (diabetes-associated protein in insulin-sensitive tissue) results in loss of ATP synthase in mitochondria. J Biol Chem (2011) 1.08
Evaluation of multidrug efflux pump inhibitors by a new method using microfluidic channels. PLoS One (2011) 1.07
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